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  • 1
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: p = 0.05); if two surgeons operated concurrently, THO could be performed 40 minutes quicker than THO or ILO performed by a single surgeon (p= 0.018). The mean initial intensive care unit stay was 2.9 days for ILO versus 1.7 days for THO (p= 0.014). The 30-day mortality was 5.1%; total in-hospital mortality was 7.1% with no difference for operation type. There were similar morbidity rates for the procedures. Kaplan-Meier survival analysis indicated no significant effect of surgical technique; there were no apparent advantages for either operation when patients were compared by tumor type or matched for stage. Hence THO is a valid alternative to ILO, particularly for stage II and III cancer.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 6 (1982), S. 596-601 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'étude de 114 sujets qui ont subi une vagotomie hypersélective permet de constater que les résultats sont satisfaisants lorsque l'opération a été pratiquée pour un ulcère duodénal (taux de récidive 5.8%, taux Visick III et IV 16%) mais qu'ils sont mauvais quand elle a été réalisée pour traiter l'ulcère prépylorique ou l'association ulcère gastrique et ulcère duodénal (taux de récidive 44%, taux Visick III et IV 62%). En conclusion la vagotomie hypersélective est l'opération de choix de l'ulcère duodénal mais ses résultats sont décevants quand elle concerne l'ulcère gastrique.
    Notes: Abstract A review of 114 patients following parietal cell vagotomy (PCV) is presented, showing a satisfactory result in duodenal ulcer patients (recurrence rate, 5.8%; Visick grade III and IV, 16%) but unsatisfactory results in patients with prepyloric or combined duodenal and gastric ulcers (recurrence rate, 44%; Visick grade III and IV, 62%). We conclude that parietal cell vagotomy is an excellent operation for duodenal ulcer, but it is unsatisfactory when there is evidence of past or present gastric ulceration.
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  • 3
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé On a utilisé chez 10 patients un manchon gonflable contrôlé à travers la peau et inséré autour du greffon pour changer le diamètre d'un shunt portacave en H. Gonfler le manchon diminue le diamètre du shunt en augmentant la pression porte ce qui réduit le débit du shunt. L'utilisation du shunt a été cliniquement décisive chez 3 des 7 patients ayant survécu à long terme. La réduction du diamètre du shunt a amélioré l'état clinique de 2 patients ayant une encéphalopathie, et la réouverture du shunt fermé par ce moyen a diminué l'ascite chez un troisième. Des modifications du débit porte après gonflage du manchon étaient toujours visibles à 6 mois par échographie et Doppler. On conclut qu'il faut continuer à expérimenter ce type de shunt portocave à débit variable.
    Abstract: Resumen Hemos desarrollado un manguito y reservorio de implantación subcutánea, el cual, mediante control percutáneo, permite modificar el diámetro de los “shunts” portacava en H; ha sido utilizado en 10 pacientes. Al inflar el manguito se comprime el injerto en H, con lo cual se aumenta la presión portal y se reduce el flujo a través del “shunt.” El uso del manguito ha sido de beneficio clínico en 3 de 7 sobrevivientes a largo plazo. La comprensión del “shunt” mejoró el estado clínico de 2 pacientes con encefalopatía, y su reapertura mejoró la ascitis en el tercer paciente. Estudios con ultrasonido duplex y ultrasonido profundo han demostrado una alteración en el flujo portal después de inflar el manguito a los 6 meses. Nuestra conclusión es que se justifica continuar desarrollando esta prótesis que permite establecer un “shunt” portacava en H controlado.
    Notes: Abstract A percutaneously-controlled inflatable cuff which can change the diameter of a portacaval H-graft has been developed and used in 10 patients. When inflated, the cuff narrows the H-graft to increase portal pressure and reduce shunting. Use of the cuff has been of clinical significance in 3 of 7 long-term surviving patients. Narrowing the shunt improved the clinical state in 2 patients with encephalopathy, and reopening a closed shunt improved ascites in the third patient. Duplex ultrasound and deep Doppler have demonstrated an alteration of hepatic portal blood flow following inflation of the cuff after 6 months. It is concluded that further development of this controlled portacaval H-graft is warranted.
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  • 4
    ISSN: 1573-2568
    Keywords: SPHINCTER OF ODDI DYSFUNCTION ; SMALL BOWEL MOTILITY
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Postcholecystectomy patients (N = 27) withsevere recurrent biliary-like pain who had no evidenceof organic disease were subdivided into those with andthose without objective evidence of sphincter of Oddi dysfunction (SOD) based on two separatecriteria: (1) clinical criteria — elevated liverfunction tests and/or amylase with pain, and/or adilated bile duct, and/or delayed drainage at ERCP (N =14, SOD classes I and II); and (2) abnormal biliary manometry(N = 19). Prolonged (24–48 hr) ambulant recordingof duodenojejunal motor activity was performed in allpatients and interdigestive small bowel motor activity compared between patient subgroups and ahealthy control group. Phase II motor abnormality wasmore frequent in patients with, compared to thosewithout, objective clinical criteria of SOD (7/14 vs0/13, P = 0.003). Phase III abnormality also tendedto be more frequent in these patients (7/14 vs 2/13, P= 0.06). In addition, both phase III (P = 0.03) andphase II (P = 0.03) motility index (MI) was higher inpatients with sphincter dyskinesia compared to controls;phase II MI was also higher in patients with sphincterstenosis (P = 0.005). Disturbances of small bowelinterdigestive motor activity are more prevalent in postcholecystectomy patients with, compared tothose without, objective evidence of SOD, and especiallyin patients with SO dyskinesia. Postcholecystectomy SODin some patients may thus represent a component of a more generalized intestinal motordisorder.
    Type of Medium: Electronic Resource
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  • 5
    Publication Date: 2017-06-14
    Description: Regulation of mRNA translation is a major control point for gene expression and is critical for life. Of central importance is the complex between cap-bound eukaryotic initiation factor 4E (eIF4E), eIF4G, and poly(A) tail-binding protein (PABP) that circularizes mRNAs, promoting translation and stability. This complex is often targeted to regulate...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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