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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 10 (1986), S. 802-802 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé On a utilisé chez 10 patients un manchon gonflable contrôlé à travers la peau et inséré autour du greffon pour changer le diamètre d'un shunt portacave en H. Gonfler le manchon diminue le diamètre du shunt en augmentant la pression porte ce qui réduit le débit du shunt. L'utilisation du shunt a été cliniquement décisive chez 3 des 7 patients ayant survécu à long terme. La réduction du diamètre du shunt a amélioré l'état clinique de 2 patients ayant une encéphalopathie, et la réouverture du shunt fermé par ce moyen a diminué l'ascite chez un troisième. Des modifications du débit porte après gonflage du manchon étaient toujours visibles à 6 mois par échographie et Doppler. On conclut qu'il faut continuer à expérimenter ce type de shunt portocave à débit variable.
    Abstract: Resumen Hemos desarrollado un manguito y reservorio de implantación subcutánea, el cual, mediante control percutáneo, permite modificar el diámetro de los “shunts” portacava en H; ha sido utilizado en 10 pacientes. Al inflar el manguito se comprime el injerto en H, con lo cual se aumenta la presión portal y se reduce el flujo a través del “shunt.” El uso del manguito ha sido de beneficio clínico en 3 de 7 sobrevivientes a largo plazo. La comprensión del “shunt” mejoró el estado clínico de 2 pacientes con encefalopatía, y su reapertura mejoró la ascitis en el tercer paciente. Estudios con ultrasonido duplex y ultrasonido profundo han demostrado una alteración en el flujo portal después de inflar el manguito a los 6 meses. Nuestra conclusión es que se justifica continuar desarrollando esta prótesis que permite establecer un “shunt” portacava en H controlado.
    Notes: Abstract A percutaneously-controlled inflatable cuff which can change the diameter of a portacaval H-graft has been developed and used in 10 patients. When inflated, the cuff narrows the H-graft to increase portal pressure and reduce shunting. Use of the cuff has been of clinical significance in 3 of 7 long-term surviving patients. Narrowing the shunt improved the clinical state in 2 patients with encephalopathy, and reopening a closed shunt improved ascites in the third patient. Duplex ultrasound and deep Doppler have demonstrated an alteration of hepatic portal blood flow following inflation of the cuff after 6 months. It is concluded that further development of this controlled portacaval H-graft is warranted.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 16 (1992), S. 139-140 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ultrasonic localization of parathyroid tissue has been attempted in 24 patients with hyperparathyroidism prior to surgical exploration of the neck. All 24 patients had biochemically proven hyperparathyroidism. Standard contact diagnostic ultrasound equipment fitted with a 5 MHz transducer was used, and transverse and longitudinal scans of the region of the thyroid gland were performed at 5 mm intervals. The normal anatomical structures identified were the lobes of the thyroid gland, trachea, common carotid arteries, and jugular veins. The longus colli muscle on each side was used as a major landmark. These structures define the site where most parathyroid glands are found in the neck. In 18 of the 24 patients the suspected parathyroid tumor was visualized preoperatively and confirmed at operation. The abnormal glands ranged in size from 5 to 12 mm in transverse diameter. In 3 patients false-positive diagnoses were made by ultrasound; at operation the abnormalities proved to be thyroid nodules protruding from the posterior surface of the thyroid gland. Ultrasonography is of little value in the presence of multinodular goiter. Three adenomas and 3 hyperplastic parathyroid glands greater than 5 mm in diameter were not identified. Localization of enlarged parathyroid glands by echography may be difficult when normal anatomical landmarks are altered by the presence of multinodular goiter or because of previous surgery. The sensitivity of this technique for identifying in the neck parathyroid glands larger than 5 mm in diameter was found to be 79.3% with 11.5% false-positive and 8.6% falsenegative results.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 3 (1979), S. 227-228 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 16 (1992), S. 716-717 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 2 (1978), S. 316-317 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Le cancer de la thyroïde est rare mais parfois la thyroïdectomie est préconisée uniquement pour l'éliminer formellement. Le but de cette étude a été de déterminer le rendement de l'analyse des cancers folliculaires par l'utilisation de la résonance magnétique de protons. La spectroscopie par résonance magnétique a été employée sur les tissus thyroïdes prélevés à partir de 98 pièces opératoires consécutives, comportant soit des nodules solitaires soit des tissus à prédominance nodulaire, et les résultats ont été comparés a ceux obtenus à partir des prélèvements. A été évaluée l'économie potentielle chez tous les patients ayant
    Abstract: Resumen El cáncer de la glándula tiroides es una entidad rara; sin embargo, muchas tiroidectomías continúan siendo realizadas simplemente para excluir el diagnóstico de malignidad. El propósito del presente estudio fue el de determinar los potencrales ahorros en costo asociados con el uso de resonancia magnética de protones para el estudio de neoplasmas foliculares. Se practicó espectrografía por resonancia magnética de protones en tejidos obtenidos, en el momento de la cirugía, de 98 nódulos solitarios consecutivos. También se practicaron biopsias con aguja fina de especímenes operatorios valorados por resonancia magnética y tales estudios fueron comparados con los logrados de los especímenes operatorios. Se hizo un estimativo de los potenciales ahorros en costos mediante la comparación de los datos de la resonancia magnética con las indicaciones para practicar cirugía y la patología en todos los pacients sometidos a tiroidectomía en un período de 10 años. La espectroscopia por resonancia magnética de protones fue capaz de distinguir entre un tejido tiroideo normal y un cáncer tiroideo invasivo con un grado de especificidad del 100%. Los adenomas folicular benignos caen en dos grupos: 44% con un patrón espectral comparable al de la tiroides normal, y 56% con un patrón espectral alterado más comparable al perfil de la resonancia magnética. La espectroscopia por resonancia magnetica de protones en biopsias con aguja fina reveló espectros similares a los de los tejidos del mismo paciente.
    Notes: Abstract Thyroid cancer is rare, but many thyroidectomies continue to be performed simply to exclude a diagnosis of malignancy. The purpose of this study was to determine the potential financial savings associated with the use of proton magnetic resonance analysis of follicular neoplasms. Proton magnetic resonance spectroscopy was performed on tissue obtained at the time of surgery from 98 consecutive solitary or dominant thyroid nodules. Fine-needle biopsies were also performed on operative specimens, and the tissues assessed by proton magnetic resonance; these spectra were then compared with those obtained from tissue specimens. An estimate of potential savings was obtained by comparing the magnetic resonance data with the indications for surgery and pathology on all patients having thyroidectomy over a 10-year period. Proton magnetic resonance spectroscopy was able to distinguish between normal thyroid tissue and invasive thyroid cancer with 100% specificity. Benign follicular adenomas fall into two groups: 44% having a spectral pattern comparable with normal thyroid, and the remaining 56% demonstrating an altered spectral pattern more comparable to the malignant magnetic resonance profile. Proton magnetic resonance spectroscopy on fine-needle biopsy specimens produced spectra similar to those from tissues from the same patient. From a fine-needle biopsy specimen, proton magnetic resonance spectroscopy can identify a group of benign follicular adenomas with spectral profiles akin to those of normal thyroid cells, thus avoiding the need for unnecessary surgical excision. The potential savings in one surgical unit alone were over $1 million in 10 years.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-7217
    Keywords: estrogen receptor ; menstrual cycle ; progesterone receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary There is controversy in the literature regarding the effects of endogenous hormones on estrogen receptors (ER) and progesterone receptors (PR) in young women with breast cancer. We studied 117 young women with primary breast cancer and assessed their breast biopsies for ER and PR. The women had a record of their last menstrual period prior to breast biopsy. The menstrual cycle was divided into four phases — early proliferative (days 1–7), late proliferative (days 8–15), early secretory (days 16–22), and late secretory (days 23–30). There were lower levels of both ER and PR in biopsies excised during the early secretory phase than in other phases of the cycle; early proliferative phase receptor positive medians of ER = 77 fmol/mg protein and PR = 467 fmol/mg protein fell to ER = 28 fmol/mg and PR = 128 fmol/mg protein in the early secretory phase.
    Type of Medium: Electronic Resource
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