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  • 1
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Entomology 46 (2001), S. 111-138 
    ISSN: 0066-4170
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Abstract St. Louis encephalitis virus was first identified as the cause of human disease in North America after a large urban epidemic in St. Louis, Missouri, during the summer of 1933. Since then, numerous outbreaks of St. Louis encephalitis have occurred throughout the continent. In south Florida, a 1990 epidemic lasted from August 1990 through January 1991 and resulted in 226 clinical cases and 11 deaths in 28 counties. This epidemic severely disrupted normal activities throughout the southern half of the state for 5 months and adversely impacted tourism in the affected region. The accurate forecasting of mosquito-borne arboviral epidemics will help minimize their impact on urban and rural population centers. Epidemic predictability would help focus control efforts and public education about epidemic risks, transmision patterns, and elements of personal protection that reduce the probability of arboviral infection. Research associated with arboviral outbreaks has provided an understanding of the strengths and weaknesses associated with epidemic prediction. The purpose of this paper is to review lessons from past arboviral epidemics and determine how these observations might aid our ability to predict and respond to future outbreaks.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science, Ltd
    Molecular microbiology 40 (2001), S. 0 
    ISSN: 1365-2958
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: DNA ligases join breaks in the phosphodiester backbone of DNA molecules and are used in many essential reactions within the cell. All DNA ligases follow the same reaction mechanism, but they may use either ATP or NAD+ as a cofactor. All Bacteria (eubacteria) contain NAD+-dependent DNA ligases, and the uniqueness of these enzymes to Bacteria makes them an attractive target for novel antibiotics. In addition to their NAD+-dependent enzymes, some Bacteria contain genes for putative ATP-dependent DNA ligases. The requirement for these different isozymes in Bacteria is unknown, but may be related to their utilization in different aspects of DNA metabolism. The putative ATP-dependent DNA ligases found in Bacteria are most closely related to proteins from Archaea and viruses. Phylogenetic analysis suggests that all NAD+-dependent DNA ligases are closely related, but the ATP-dependent enzymes have been acquired by Bacterial genomes on a number of separate occasions.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    Publikationsdatum: 2019-08-12
    Beschreibung: he Year of Polar Prediction (YOPP) is focused on a number of Special Observing Periods (SOPs) of two to three months’ duration in both the Northern and Southern Hemispheres. One feature of the SOPs is a program of enhanced radiosonde and buoy measurements contributing to assessments of how the extra observations support improved forecast skills. Another activity resulting from the SOPs is the YOPP Supersite Model Intercomparison Project (YOPPsiteMIP). The YOPPsiteMIP concept is unique compared to Climate Model Intercomparison Projects (CMIPs) because of (1) a focus on Numerical Weather Prediction (NWP) scales, processes and improvements, (2) the selection of polar, intensive, surface observing locations (YOPP Supersites) for which the NWP centers will create high-resolution model outputs and (3) special merged, observation outputs for the YOPP Supersites matched to the model outputs. These unique datasets of matched model time-step output and multi-variate high-frequency observations will enable detailed analysis of fast, small-scale processes. Example processes of interest are coupling mechanisms between the atmosphere, ocean, land and ice; cloud/precipitation micro- and macro-physics; the energy budgets over land, ocean and ice; and structure of the planetary boundary layer and the ocean mixed layer. The YOPPsiteMIP planning has focused so far on Arctic terrestrial YOPP Supersites, however, discussions are initiated on expanding the concept to selected Antarctic sites, as well as to ships and ice-stations in the Arctic Ocean. Preliminary results of the observation-model process-based evaluations at the YOPP Supersites relevant to environmental predictions ranging from weather to S2S scales will be presented.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Conference , notRev
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
    facet.materialart.
    Unbekannt
    JOHN WILEY & SONS LTD
    In:  EPIC3Quarterly Journal of the Royal Meteorological Society, JOHN WILEY & SONS LTD, 145(725), pp. 3846-3862, ISSN: 0035-9009
    Publikationsdatum: 2020-05-15
    Beschreibung: Recent studies have suggested that Arctic teleconnections affect the weather of the midlatitudes on time‐scales relevant for medium‐range weather forecasting. In this study, we use several numerical experimentation approaches with a state‐of‐the‐art global operational numerical weather prediction system to investigate this idea further. Focusing on boreal winter, we investigate whether the influence of the Arctic on midlatitude weather, and the impact of the current Arctic observing system on the skill of medium‐range weather forecasts in the midlatitudes is more pronounced in certain flow regimes. Using so‐called Observing System Experiments, we demonstrate that removing in situ or satellite observations from the data assimilation system, used to create the initial conditions for the forecasts, deteriorates midlatitude synoptic forecast skill in the medium‐range, particularly over northern Asia. This deterioration is largest during Scandinavian Blocking episodes, during which: (a) error growth is enhanced in the European‐Arctic, as a result of increased baroclinicity in the region, and (b) high‐amplitude planetary waves allow errors to propagate from the Arctic into midlatitudes. The important role played by Scandinavian Blocking, in modulating the influence of the Arctic on midlatitudes, is also corroborated in relaxation experiments, and through a diagnostic analysis of the ERA5 reanalysis and reforecasts.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
    Publikationsdatum: 2016-10-04
    Beschreibung: The Year of Polar Prediction (YOPP) is planned for mid-2017 to mid-2019, centred on 2018. Its goal is to enable a significant improvement in environmental prediction capabilities for the polar regions and beyond, by coordinating a period of intensive observing, modelling, prediction, verification, user-engagement and education activities. With a focus on time scales from hours to a season, YOPP is a major initiative of the World Meteorological Organization’s World Weather Research Programme (WWRP) and a key component of the Polar Prediction Project (PPP). YOPP is being planned and coordinated by the PPP Steering Group together with representatives from partners and other initiatives, including the World Climate Research Programme’s Polar Climate Predictability Initiative (PCPI). The objectives of YOPP are to: 1. Improve the existing polar observing system (enhanced coverage, higher-quality observations). 2. Gather additional observations through field programmes aimed at improving understanding of key polar processes. 3. Develop improved representation of key polar processes in (un)coupled models used for prediction. 4. Develop improved (coupled) data assimilation systems accounting for challenges in the polar regions such as sparseness of observational data. 5. Explore the predictability of the atmosphere-cryosphere-ocean system, with a focus on sea ice, on time scales from hours to a season. 6. Improve understanding of linkages between polar regions and lower latitudes, assess skill of models representing these linkages, and determine the impact of improved polar prediction on forecast skill in lower latitudes. 7. Improve verification of polar weather and environmental predictions to obtain better quantitative knowledge on model performance, and on the skill, especially for user- relevant parameters. 8. Identify various stakeholders and establish their decisionmaking needs with respect to weather, climate, ice, and related environmental services. 9. Assess the costs and benefits of using predictive information for a spectrum of users and services. 10. Provide training opportunities to generate a sound knowledge base (and its transfer across generations) on polar prediction related issues. YOPP is implemented in three distinct phases. During the YOPP Preparation Phase (2013 through to mid-2017) this Implementation Plan was developed, which includes key outcomes of consultations with partners at the YOPP Summit in July 2015. Plans will be further developed and refined through focused international workshops. There will be engagement with stakeholders and arrangement of funding, coordination of observations and modelling activities, and preparatory research. During the YOPP Core Phase (mid-2017 to mid-2019), four elements will be staged: intensive observing periods for both hemispheres, a complementary intensive modelling and prediction period, a period of enhanced monitoring of forecast use in decisionmaking including verification, and a special educational effort. Finally, during the YOPP Consolidation Phase (mid-2019 to 2022) the legacy of data, science and publications will be organized. The WWRP-PPP Steering Group provides endorsement throughout the YOPP phases for projects that contribute to YOPP. This process facilitates coordination and enhances visibility, communication, and networking.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Miscellaneous , notRev
    Format: application/pdf
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
    Publikationsdatum: 2017-01-27
    Beschreibung: Polar regions are experiencing rapid climate change, faster than elsewhere on Earth with consequences for the weather and sea ice. This change is opening up new possibilities for businesses such as tourism, shipping, fisheries and oil and gas extraction, but also bringing new risks to delicate polar environments. Effective weather and climate prediction is essential to managing these risks, however our ability to forecast polar environmental conditions over periods from days to decades ahead falls far behind our abilities in the mid-latitudes. In order to meet the growing societal need for young scientists trained in this area, a Polar Prediction School for early career scientists from around the world was held in April 2016.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
    Format: application/pdf
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
    Publikationsdatum: 2017-01-27
    Beschreibung: Recent decades have seen significant developments in climate prediction capabilities at seasonal-to-interannual timescales. However, until recently the potential of such systems to predict Arctic climate had rarely been assessed. This paper describes a multi-model predictability experiment which was run as part of the Arctic Predictability and Prediction On Seasonal to Interannual Timescales (APPOSITE) project. The main goal of APPOSITE was to quantify the timescales on which Arctic climate is predictable. In order to achieve this, a coordinated set of idealised initial-value predictability experiments, with seven general circulation models, was conducted. This was the first model intercomparison project designed to quantify the predictability of Arctic climate on seasonal to interannual timescales. Here we present a description of the archived data set (which is available at the British Atmospheric Data Centre), an assessment of Arctic sea ice extent and volume predictability estimates in these models, and an investigation into to what extent predictability is dependent on the initial state. The inclusion of additional models expands the range of sea ice volume and extent predictability estimates, demonstrating that there is model diversity in the potential to make seasonal-to-interannual timescale predictions. We also investigate whether sea ice forecasts started from extreme high and low sea ice initial states exhibit higher levels of potential predictability than forecasts started from close to the models' mean state, and find that the result depends on the metric. Although designed to address Arctic predictability, we describe the archived data here so that others can use this data set to assess the predictability of other regions and modes of climate variability on these timescales, such as the El Niño–Southern Oscillation.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
    Format: application/pdf
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
    Publikationsdatum: 2017-01-27
    Beschreibung: The Year of Polar Prediction (YOPP) has the mission to enable a significant improvement in environmental prediction capabilities for the polar regions and beyond, by coordinating a period of intensive observing, modelling, prediction, verification, user- engagement and education activities. The YOPP Core Phase will be from mid-2017 to mid-2019, flanked by a Preparation Phase and a Consolidation Phase. YOPP is a key component of the World Meteorological Organization – World Weather Research Programme (WMO-WWRP) Polar Prediction Project (PPP). The objectives of YOPP are to: 1. Improve the existing polar observing system (better coverage, higher-quality observations); 2. Gather additional observations through field programmes aimed at improving understanding of key polar processes; 3. Develop improved representation of key polar processes in coupled (and uncoupled) models used for prediction; 4. Develop improved (coupled) data assimilation systems accounting for challenges in the polar regions such as sparseness of observational data; 5. Explore the predictability of the atmosphere-cryosphere-ocean system, with a focus on sea ice, on time scales from days to seasons; 6. Improve understanding of linkages between polar regions and lower latitudes and assess skill of models representing these linkages; 7. Improve verification of polar weather and environmental predictions to obtain better quantitative knowledge on model performance, and on the skill, especially for user-relevant parameters; 8. Demonstrate the benefits of using predictive information for a spectrum of user types and services; 9. Provide training opportunities to generate a sound knowledge base (and its transfer across generations) on polar prediction related issues. The PPP Steering Group provides endorsement for projects that contribute to YOPP to enhance coordination, visibility, communication, and networking. This White Paper is based largely on the much more comprehensive YOPP Implementation Plan (WWRP/PPP No. 3 – 2014), but has an emphasis on Arctic observations.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , peerRev
    Format: application/pdf
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 9
    facet.materialart.
    Unbekannt
    Wiley
    In:  EPIC3Geophysical Research Letters, Wiley, ISSN: 0094-8276
    Publikationsdatum: 2016-02-29
    Beschreibung: Skillful sea ice forecasts from days to years ahead are becoming increasingly important for the operation and planning of human activities in the Arctic. Here we analyze the potential predictability of the Arctic sea ice edge in six climate models. We introduce the integrated ice-edge error (IIEE), a user-relevant verification metric defined as the area where the forecast and the “truth” disagree on the ice concentration being above or below 15%. The IIEE lends itself to decomposition into an absolute extent error, corresponding to the common sea ice extent error, and a misplacement error. We find that the often-neglected misplacement error makes up more than half of the climatological IIEE. In idealized forecast ensembles initialized on 1 July, the IIEE grows faster than the absolute extent error. This means that the Arctic sea ice edge is less predictable than sea ice extent, particularly in September, with implications for the potential skill of end-user relevant forecasts.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
    Format: application/pdf
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  • 10
    Publikationsdatum: 2016-02-02
    Beschreibung: The polar regions have been attracting more and more attention in recent years, fuelled by the perceptible impacts of anthropogenic climate change. Polar climate change provides new opportunities, such as shorter shipping routes between Europe and East Asia, but also new risks such as the potential for industrial accidents or emergencies in ice-covered seas. Here, it is argued that environmental prediction systems for the polar regions are less developed than elsewhere. There are many reasons for this situation, including the polar regions being (historically) lower priority, with less in situ observations, and with numerous local physical processes that are less well-represented by models. By contrasting the relative importance of different physical processes in polar and lower latitudes, the need for a dedicated polar prediction effort is illustrated. Research priorities are identified that will help to advance environmental polar prediction capabilities. Examples include an improvement of the polar observing system; the use of coupled atmosphere-sea ice-ocean models, even for short-term prediction; and insight into polar-lower latitude linkages and their role for forecasting. Given the enormity of some of the challenges ahead, in a harsh and remote environment such as the polar regions, it is argued that rapid progress will only be possible with a coordinated international effort. More specifically, it is proposed to hold a Year of Polar Prediction (YOPP) from mid-2017 to mid-2019 in which the international research and operational forecasting community will work together with stakeholders in a period of intensive observing, modelling, prediction, verification, user-engagement and educational activities.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
    Format: application/pdf
    Standort Signatur Einschränkungen Verfügbarkeit
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