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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 437 (2005), S. 1326-1329 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Images of Saturn's narrow and contorted F ring returned by the Cassini spacecraft have revealed phenomena not previously detected in any planetary ring system. The perturbing effect of the inner shepherding satellite, Prometheus, seems to introduce channels through the F ring and a ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature biotechnology 23 (2005), S. 1303-1307 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Chemical genomics aims to discover small molecules that affect biological processes through the perturbation of protein function. However, determining the protein targets of bioactive compounds remains a formidable challenge. We address this problem here through the creation of a natural ...
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Titan, the largest moon of Saturn, is the only satellite in the Solar System with a substantial atmosphere. The atmosphere is poorly understood and obscures the surface, leading to intense speculation about Titan's nature. Here we present observations of Titan from the imaging science ...
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The nervous system senses peripheral damage through nociceptive neurons that transmit a pain signal. TRPA1 is a member of the Transient Receptor Potential (TRP) family of ion channels and is expressed in nociceptive neurons. TRPA1 is activated by a variety of noxious stimuli, including cold ...
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 440 (2006), S. 1120-1121 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Two principal uncertainties in predicting climate change are the net effect of water in the climate system and the way in which water will be redistributed over the surface of the planet. On page 1179 of this issue, Treydte et al. present a reconstruction of precipitation in central Asia for ...
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  • 6
    Publication Date: 2017-07-21
    Description: Reproducible climate reconstructions of the Common Era (1 CE to present) are key to placing industrial-era warming into the context of natural climatic variability. Here we present a community-sourced database of temperature-sensitive proxy records from the PAGES2k initiative. The database gathers 692 records from 648 locations, including all continental regions and major ocean basins. The records are from trees, ice, sediment, corals, speleothems, documentary evidence, and other archives. They range in length from 50 to 2000 years, with a median of 547 years, while temporal resolution ranges from biweekly to centennial. Nearly half of the proxy time series are significantly correlated with HadCRUT4.2 surface temperature over the period 1850–2014. Global temperature composites show a remarkable degree of coherence between high- and low-resolution archives, with broadly similar patterns across archive types, terrestrial versus marine locations, and screening criteria. The database is suited to investigations of global and regional temperature variability over the Common Era, and is shared in the Linked Paleo Data (LiPD) format, including serializations in Matlab, R and Python.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Format: application/pdf
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  • 7
    Publication Date: 2022-05-25
    Description: © The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Climate of the Past 9 (2013): 1481-1493, doi:10.5194/cp-9-1481-2013.
    Description: We present a Bayesian model for estimating the parameters of the VS-Lite forward model of tree-ring width for a particular chronology and its local climatology. The scheme also provides information about the uncertainty of the parameter estimates, as well as the model error in representing the observed proxy time series. By inferring VS-Lite's parameters independently for synthetically generated ring-width series at several hundred sites across the United States, we show that the algorithm is skillful. We also infer optimal parameter values for modeling observed ring-width data at the same network of sites. The estimated parameter values covary in physical space, and their locations in multidimensional parameter space provide insight into the dominant climatic controls on modeled tree-ring growth at each site as well as the stability of those controls. The estimation procedure is useful for forward and inverse modeling studies using VS-Lite to quantify the full range of model uncertainty stemming from its parameterization.
    Description: This work was supported in part by an American Association of University Women Dissertation Fellowship and grants NSF ATM-0724802, NSF ATM-0902715, NSF DMS- 1204892, and NOAA NA060OAR4310115.
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/zip
    Format: application/pdf
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  • 8
    Publication Date: 2022-05-25
    Description: © The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Quaternary Science Reviews 76 (2013): 16-28, doi:10.1016/j.quascirev.2013.05.024.
    Description: A proxy system model may be defined as the complete set of forward and mechanistic processes by which the response of a sensor to environmental forcing is recorded and subsequently observed in a material archive. Proxy system modeling complements and sharpens signal interpretations based solely on statistical analyses and transformations; provides the basis for observing network optimization, hypothesis testing, and data-model comparisons for uncertainty estimation; and may be incorporated as weak but mechanistically-plausible constraints into paleoclimatic reconstruction algorithms. Following a review illustrating these applications, we recommend future research pathways, including development of intermediate proxy system models for important sensors, archives, and observations; linking proxy system models to climate system models; hypothesis development and evaluation; more realistic multi-archive, multi-observation network design; examination of proxy system behavior under extreme conditions; and generalized modeling of the total uncertainty in paleoclimate reconstructions derived from paleo-observations.
    Description: MNE and DMT were funded by NOAA/C2D2 grant NA10OAR4310115; SETW gratefully acknowledges support from an American Association of UniversityWomen Dissertation Fellowship. Work cited in this review was supported by NSF grants 0349356, 0724802 and 0902715, NOAA grants NA06OAR4310115 and NA08OAR4310682, and the University of Arizona’s Department of Geosciences and Institute of the Environment.
    Keywords: Forward modeling ; Observational network optimization ; Data-model comparison ; Hypothesis evaluation ; Reconstruction ; Uncertainty modeling
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
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  • 9
    Publication Date: 2022-05-25
    Description: © The Author(s), 2015. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Paleoceanography 30 (2015): 226–252, doi:10.1002/2014PA002717.
    Description: Most annually resolved climate reconstructions of the Common Era are based on terrestrial data, making it a challenge to independently assess how recent climate changes have affected the oceans. Here as part of the Past Global Changes Ocean2K project, we present four regionally calibrated and validated reconstructions of sea surface temperatures in the tropics, based on 57 published and publicly archived marine paleoclimate data sets derived exclusively from tropical coral archives. Validation exercises suggest that our reconstructions are interpretable for much of the past 400 years, depending on the availability of paleoclimate data within, and the reconstruction validation statistics for, each target region. Analysis of the trends in the data suggests that the Indian, western Pacific, and western Atlantic Ocean regions were cooling until modern warming began around the 1830s. The early 1800s were an exceptionally cool period in the Indo-Pacific region, likely due to multiple large tropical volcanic eruptions occurring in the early nineteenth century. Decadal-scale variability is a quasi-persistent feature of all basins. Twentieth century warming associated with greenhouse gas emissions is apparent in the Indian, West Pacific, and western Atlantic Oceans, but we find no evidence that either natural or anthropogenic forcings have altered El Niño–Southern Oscillation-related variance in tropical sea surface temperatures. Our marine-based regional paleoclimate reconstructions serve as benchmarks against which terrestrial reconstructions as well as climate model simulations can be compared and as a basis for studying the processes by which the tropical oceans mediate climate variability and change.
    Description: J.E.T. and K.J.A. acknowledge Woods Hole Oceanographic Institution for internal support. K.J.A. acknowledges the Frank and Lisina Hoch Endowed Fund at the Woods Hole Oceanographic Institution for support. N.J.A. is supported by an Australian Research Council QEII fellowship (DP110101161), and this research contributes to ARC Discovery Grant DP140102059. M.N.E. is supported by NSF/ATM0902794 and NSF/ATM0902715. J.Z. was supported by an Indian Ocean Marine Research Centre fellowship and an Honorary Research Fellowship by the University of the Witwatersrand. H.C.W. is supported by the Deutsche Forschungsgemeinschaft through DFG-Research Center/Cluster of Excellence “The Ocean in the Earth System” at the University of Bremen (MARUM Fellowship). C.G. acknowledges MARUM–Center for Marine Environmental Sciences for internal support. K.H.K. is supported by NOAA grant NA11OAR4310171.
    Keywords: Climate reconstruction ; Corals ; Paleoceanography ; Last millennium climate
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/msword
    Format: application/pdf
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  • 10
    Publication Date: 2020-02-06
    Description: The pre-industrial millennium is among the periods selected by the Paleoclimate Model Intercomparison Project (PMIP) for experiments contributing to the sixth phase of the Coupled Model Intercomparison Project (CMIP6) and the fourth phase of the PMIP (PMIP4). The past1000 transient simulations serve to investigate the response to (mainly) natural forcing under background conditions not too different from today, and to discriminate between forced and internally generated variability on interannual to centennial timescales. This paper describes the motivation and the experimental set-ups for the PMIP4-CMIP6 past1000 simulations, and discusses the forcing agents orbital, solar, volcanic, and land use/land cover changes, and variations in greenhouse gas concentrations. The past1000 simulations covering the pre-industrial millennium from 850 Common Era (CE) to 1849 CE have to be complemented by historical simulations (1850 to 2014 CE) following the CMIP6 protocol. The external forcings for the past1000 experiments have been adapted to provide a seamless transition across these time periods. Protocols for the past1000 simulations have been divided into three tiers. A default forcing data set has been defined for the Tier 1 (the CMIP6 past1000) experiment. However, the PMIP community has maintained the flexibility to conduct coordinated sensitivity experiments to explore uncertainty in forcing reconstructions as well as parameter uncertainty in dedicated Tier 2 simulations. Additional experiments (Tier 3) are defined to foster collaborative model experiments focusing on the early instrumental period and to extend the temporal range and the scope of the simulations. This paper outlines current and future research foci and common analyses for collaborative work between the PMIP and the observational communities (reconstructions, instrumental data).
    Type: Article , PeerReviewed
    Format: text
    Format: archive
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