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  • 1
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Neurobiology. ; Neurosciences. ; Electronic books.
    Description / Table of Contents: Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a collection of articles covering recent advances in the field of neurobiology. Topics covered include chromosome 22 deletion syndrome and schizophrenia; characterization of proteome of human cerebrospinal fluid; hormonal pathways regulating intermale and interfemale aggression; neuronal gap junctions; effects of genes and stress on the neurobiology of depression; quantitative imaging with teh MicroPET small-animal PET tomograph; understanding myelination through studying its evolution.
    Type of Medium: Online Resource
    Pages: 1 online resource (312 pages)
    Edition: 1st ed.
    ISBN: 9780080463520
    Series Statement: Issn Series ; v.Volume 73
    DDC: 573.8
    Language: English
    Note: Cover Page -- Contents -- Contributors -- Chapter 1: Chromosome 22 Deletion Syndrome And Schizophrenia -- I. Introduction -- II. 22q11DS: Mechanism of the Deletion -- III. 22q11DS: Clinical Phenotype -- IV. 22q11DS: Psychosis -- V. 22q11DS: Neuropathology -- VI. 22q11DS: Positional Cloning Schizophrenia Susceptibility Loci -- VII. 22q11DS: Murine Models -- VIII. Catechol-O-Methyltransferase -- IX. Conclusions -- References -- Chapter 2: Characterization of Proteome of Human Cerebrospinal Fluid -- I. Introduction -- II. Materials and Methods -- A. Collection of Human CSF by Lumbar Puncture and Exclusion Criteria -- B. CSF Sample Preparation and Fractionation with SDS-PAGE -- C. In-Gel Digestion -- D. Protein Identification Using LC Followed by LCQ-MS -- E. Protein Identification Using Off-Line SCX Chromatography Followed by LTQ-FT MS -- F. Data Processing and Analysis -- III. Results -- A. Proteins Identified by muLC-LCQ-MS/MS -- B. Proteins Identified by nanoLC-LTQ-FT MS/MS Following Off-Line SCX Separation -- C. Reexamination of Previously Identified Proteins -- D. Discussion -- Acknowledgments -- References -- Chapter 3: Hormonal Pathways Regulating Intermale And Interfemale Aggression -- I. Introduction -- A. Common Regulatory Concepts in Males and Females -- II. Females -- A. DHEA as a Neurosteroid -- III. Males -- A. Regulation in the Adult -- B. Neural Steroid Receptors -- IV. Hormonal Modulation of Serotonin Function -- V. Conclusions -- Acknowledgments -- References -- Chapter 4: Neuronal GAP Junctions: Expression, Function, And Implications For Behavior -- I. A Brief History of Gap Junctions -- II. Gap Junction Structure -- III. Gap Junctions in the Brain -- IV. Electrical Coupling in the Brain -- V. Properties and Function of Electrical Synapses -- VI. Modulation of Electrical Synapses and Gap-Junctional Coupling. , VII. Use-Dependent Plasticity -- VIII. Local Factors: Voltage, pH, and Calcium -- IX. Neurotransmitter and Second Messenger Modulation -- X. Concluding Remarks -- References -- Chapter 5: Effects of Genes and Stress on the Neurobiology of Depression -- I. Introduction -- II. Stress and Depression -- III. Genetics and Depression -- IV. Serotonergic System -- V. Candidate Gene Studies of the Serotonergic System -- A. Serotonin Transporter -- B. Serotonin Receptors -- C. Other Serotonin Receptors -- D. Tryptophan Hydroxylase -- VI. Current Stress and the Serotonergic System -- A. Early Life Stress and the Serotonergic System -- VII. Gene Stress Interaction -- VIII. Hypothalamic-Pituitary-Adrenocortical (HPA) Axis -- A. Genetics and the HPA Axis -- B. Early Life Stress and the HPA Axis -- IX. Noradrenergic System -- A. Genetics and the Noradrenergic System -- B. Current Stress and the Noradrenergic System -- C. Early Life Stress and the Noradrenergic System -- X. Dopaminergic System in Depression -- A. Genetics and the Dopaminergic System -- B. Current Stress and the Dopaminergic System -- C. Early Life Stress and the Dopaminergic System -- XI. GABAergic System -- A. Genetics and the GABAergic System -- B. Early Life Stress and the GABAergic System -- XII. Brain Derived Neurotrophic Factor -- A. Genetics and BDNF -- B. Current Stress and BDNF -- C. Early Life Stress and BDNF -- XIII. Conclusions -- References -- Chapter 6: Quantitative Imaging with the Micro-pet Small-Animal Pet Tomograph -- I. Introduction -- II. Setup and Calibration -- A. Scanner Setup -- B. Calibration -- C. Quality Control -- D. External Radioactivity Measurements -- E. Animal Positioning -- III. Physical Corrections -- A. Randoms -- B. Deadtime -- C. Attenuation -- D. Scatter -- E. Normalization -- F. Natural Background Radioactivity of LSO -- IV. Image Reconstruction. , V. Data Analysis -- A. Anatomical Segmentation and Image Registration -- B. Partial Volume Correction -- VI. Conclusions -- References -- Chapter 7: Understanding Myelination Through Studying Its Evolution -- I. Introduction -- II. Evidence that Glial Cells First Interacted with Large Axons in a "Nonmyelin" Relationship -- III. Myelin-like Sheaths in Invertebrates -- A. Morphological Considerations -- B. Physiological Properties of Invertebrate Myelinated Fibers -- C. Biochemical Properties of Invertebrate Myelinated Fibers -- D. Concluding Remarks on Invertebrate Fiber Myelination -- IV. Vertebrate Myelinated Nervous System -- A. Morphological Features -- B. Biochemical and Molecular Features of Vertebrate Myelin Sheaths -- C. Differentiation of Myelinating CNS and PNS Glial Cells -- V. Use of Comparative Myelin Studies to Understand CNS Regeneration -- A. Myelin Inhibition, a Historical Perspective -- B. Characterization of Regeneration Inhibitors in Mammals -- C. Phylogeny of CNS Regeneration -- D. Comparative Genomics of the Myelin Inhibitory Machinery -- E. CNS Regeneration Despite Myelin Inhibitors-Does the Immune System Make the Difference? -- F. Conclusion: Collision of Biological Necessity and Clinical Needs -- VI. Future Studies of Myelin Evolution -- Acknowledgments -- References -- Index -- Contents of Recent Volumes.
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  • 2
    Online Resource
    Online Resource
    London :Elsevier Science & Technology,
    Keywords: Neurobiology. ; Neurosciences. ; Electronic books.
    Description / Table of Contents: Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.
    Type of Medium: Online Resource
    Pages: 1 online resource (305 pages)
    Edition: 1st ed.
    ISBN: 9780080458311
    Series Statement: Issn Series ; v.Volume 63
    DDC: 573.8
    Language: English
    Note: front cover -- copyright -- table of contents -- contributors -- MAPPING NEURORECEPTORS AT WORK: ON THE DEFINITION AND INTERPRETATION OF BINDING POTENTIALS AFTER 20 YEARS OF PROGRESS -- I. Twenty Years of Progress -- II. Remaining Issues -- III. Solutions -- References 1 -- MITOCHONDRIAL DYSFUNCTION IN BIPOLAR DISORDER: FROM MAGNETIC RESONANCE SPECTROSCOPIC FINDINGS TO THEIR MOLECULAR MECHANISMS -- I. Introduction 2 -- II. Phosphorus-31 Magnetic Resonance Spectroscopy -- III. Near-Infrared Spectroscopy -- IV. Molecular Genetic Findings -- V. Roles of Mitochondrial Calcium Regulation -- VI. Conclusions -- References 2 -- LARGE-SCALE MICROARRAY STUDIES OF GENE EXPRESSION IN MULTIPLE REGIONS OF THE BRAIN IN SCHIZOPHRENIA AND ALZHEIMER'S DISEASE -- I. Introduction 3 -- II. Gene Expression Profiling Using Microarrays: Technologies Overview -- III. Postmortem Brains and Gene Expression Studies -- IV. Comparison of Gene Expression Profiles among Normal Brain Regions -- V. Gene Expression Profiles of Brain Regions in Alzheimer's Disease -- VI. Gene Expression Profiling in Schizophrenia -- VII. Future Perspectives -- References 3 -- REGULATION OF SEROTONIN 2C RECEPTOR PRE-mRNA EDITING BY SEROTONIN -- I. Introduction 4 -- II. Modification of RNA Sequences by RNA Editing via Hydrolytic Deaminations of Adenosines -- III. Enzymes Responsible for A-to-I Editing and Their Substrate Requirements -- IV. A-to-I Editing of the 5- HT2C Receptor Pre- mRNA -- V. Modulation of 5- HT2C Receptor Function by RNA Editing -- VI. 5- HT2C Pre- mRNA Editing Responses to Sustained Changes of Postsynaptic 5-HT2C Receptor Activation -- VII. 5- HT2C Pre- mRNA Editing in the Human Prefrontal Cortex and Alterations in Editing-Site Preferences in Brains of Subjects with Major Depression -- VIII. Conclusions and Future Directions -- References 4. , THE DOPAMINE HYPOTHESIS OF DRUG ADDICTION: HYPODOPAMINERGIC STATE -- I. Drug Addiction as a Brain Disease -- II. The Mesolimbic Dopamine System -- III. Behavioral Animal Models -- IV. Biochemical Studies -- V. Primate Studies -- VI. Conclusions -- Acknowledgments 5 -- References 5 -- HUMAN AND ANIMAL SPONGIFORM ENCEPHALOPATHIES ARE AUTOIMMUNE DISEASES: A NOVEL THEORY AND ITS SUPPORTING EVIDENCE -- I. Introduction 6 -- II. A New Theory on the Mechanism of Pathogenesis of Spongiform Encephalopathies (SEs) -- III. Supporting Evidence -- IV. Early Diagnosis, Treatment, and Prevention of Various SE Diseases -- V. Conclusions -- Acknowledgments 6 -- References 6 -- ADENOSINE AND BRAIN FUNCTION -- I. Introduction 7 -- II. Regulation of Brain Adenosine Levels in the Central Nervous System -- III. Adenosine Receptors -- IV. Functions of Adenosine Receptors -- V. Adenosine-Dopamine Interactions in Brain -- VI. Phenotypes of Knockout Mice -- VII. Adenosine Receptors and Protection against Ischemic and Excitotoxic Brain Injuries -- VIII. Adenosine A2A Receptors and Neurodegenerative Disorders -- IX. Adenosine Receptors and Psychiatric Disorders -- X. Adenosine and the Regulation of Sleep- Wake Cycles -- XI. Adenosine and Epilepsy -- XII. Adenosine and Pain -- Acknowledgments 7 -- References 7 -- Index -- Contents of Recent Volumes.
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  • 3
    Online Resource
    Online Resource
    La Vergne :Royal Society of Chemistry, The,
    Keywords: Nuclear magnetic resonance - Collected works. ; Electronic books.
    Description / Table of Contents: For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage.
    Type of Medium: Online Resource
    Pages: 1 online resource (364 pages)
    Edition: 1st ed.
    ISBN: 9781847553577
    Series Statement: Issn Series
    DDC: 016.538362
    Language: English
    Note: Nuclear Magnetic Resonance -- Contents -- Chapter 1 Nuclear Shielding -- 1 Introduction -- 2 Chemical Shift Scales -- 3 Basic Aspects of Nuclear Shielding -- A Magnetic Field-dependent Chemical Shifts -- B Developments in Theory -- 4 Calculations of Nuclear Shielding -- A Ab Initio Calculations -- B Semi-empirical Calculations -- 5 Transmissions of Shielding Effects within Molecules -- A Introduction -- B Inductive and Resonance Effects -- C Magnetic Anisotropy Effects -- D The Ring Current Effects -- E Electric Field Effects -- F Intramolecular Dispersion Forces -- G Steric Effects -- H Intramolecular Hydrogen-bonding -- I Isotope Shifts -- J Shielding Anisotropies -- 6 Shieldings of Particular Nuclear Species -- A Introduction -- B Proton Chemical Shifts -- C Carbon Chemical Shifts -- D Fluorine Chemical Shifts -- E Nitrogen Chemical Shifts -- F Chemical Shifts of Nuclei Other Than H, C, F, and N -- Chapter 2 Nuclear Spin-Spin Coupling -- 1 Introduction -- 2 Basic Theory -- A Ramsey's Equations -- B The Average Energy Approximation -- C Useful General Expressions -- D The Finite Perturbation Theory (FPT) -- E Coupling by π-Electrons -- F The Variation Method -- G SI Units -- 3 Recent Theoretical Work -- A Calculations on H2 or HD -- B Ab Initio Calculations of Coupling in Small Molecules -- C Semi-empirical Calculations -- D Theoretical Work on π-Electron Coupling -- E The Anisotropy of Electron-coupled Nuclear Spin Interactions -- F Solvent Effects on Coupling -- 4 Coupling of Directly Bonded Nuclei -- A Coupling between 13C and 1H -- B Coupling between 15N and 1H -- C Coupling between 31P and 1H -- D Coupling between 1H and Other Nuclei -- E 1J(13C13C)and 1J(13C14/15N) -- F Coupling between 13C and 31P -- G Coupling between 13C and 19F -- H 1J(13CM) where M is a Metal -- I Couplings to 19F, except 1J(19F31P) -- J Couplings between 31P and 19F. , K Other One-bond Couplings involving 31P -- 5 Coupling between Atoms Separated by Two Chemical Bonds, 2J -- A Geminal Proton-Proton Coupling across Carbon -- B Geminal Proton-Proton Coupling across Other Elements -- C 2J(13CCH) -- D Coupling of Other Elements to Hydrogen through Carbon -- E 2J(19FP19F) and 2J(19FPH) -- F 2J(19FM19F), where M is a Metal -- G 2J(19FC19F) -- H 2J(13CO31P) and 2J(13CC31P) -- I 2J(31PO31P) and 2J(31PS31P) -- J 2J(31PM31P), where M is a Metal -- K Other Two-bond Couplings -- 6 Coupling between Atoms Separated by Three Chemical Bonds, 3J -- A Coupling of Hydrogen Atoms through Two Carbon Atoms -- B 3J(HNCH) and 3J(HOCH) -- C 3J(13CCCH) -- D Coupling to Fluorine through Two Carbon Atoms. 3J(HCC19F), 3J(13CCC19F), and 3J(19FCC19F) -- E Three-bond Couplings involving 31P and 1H -- F Miscellaneous Three-bond Couplings -- 7 Coupling between Nuclei Separated by Four or More Chemical Bonds -- A Long-range Coupling between Protons -- Long-range H-H Coupling in Saturated Systems -- Long-range H-H Coupling in Unsaturated Systems -- B Long-range Couplings involving at least One Nucleus other than H -- Saturated Systems-Coupling between 1H and 19F -- Saturated Systems-Coupling between Other Nuclei -- Unsaturated Systems -- C 'Through-space' Coupling -- 8 Experimental Work of Significance for the Measurement or Interpretation of SpinSpin Coupling Constants -- A Multiple-resonance Experiments -- B Bandshape Analyses -- C Effects of Paramagnetic Materials -- D Other Experimental Techniques -- Chapter 3 Nuclear Spin Relaxation -- 1 Introduction -- 2 Nuclear Spin Relaxation in Gases -- A Introduction -- B Theoretical Developments -- C Diatomic Gases -- D Polyatomic Gases -- Pure Gases -- Stepped T1/ρ vs. ρ Plot -- CH4-O2 and CH4-NO Mixtures -- E Self-diffusion Measurements -- 3 Spin Relaxation in Liquids -- A Pure Liquids. , Molecular Rotation -- Studies of Anisotropic Rotation -- Relaxation by internal rotation of functional groups -- Relaxation in water -- Determination of nuclear quadrupole coupling constants -- Studies of Scalar Relaxation -- Relaxation in glasses and viscous liquids -- B Molecular Motion and Association in Mixtures of Liquids -- C Electrolyte Solutions -- Diamagnetic Solutions -- Paramagnetic Solutions -- D Studies of Critical Phenomena in Liquids -- E 13C Relaxation Studies -- F Methods for Selective Measurement of T1 and T2 -- 4 Spin-echo Experiments in Liquids -- A Self-diffusion Measurements -- B Spin-echo Studies of Fluid Flow -- C Carr-Purcell Spin-echo Experiments -- 5 Nuclear Spin Relaxation and Diffusion in Liquid Crystals -- A Thermotropic Liquid Crystals -- B Lyotropic Liquid Crystals -- 6 Spin Relaxation in Solids -- A N.M.R. Saturation in Solids -- B Nuclear Dipolar Relaxation -- C Relaxation by Rotational Motion -- D Spin-Lattice Relaxation by Spin-Rotational and Anisotropic Chemical Shielding Interactions -- E Spin-Lattice Relaxation due to Paramagnetic Impurities -- F Spin-Lattice Relaxation by Nuclear Quadrupole Interaction -- G Spin-Lattice Relaxation Time Measurements in Miscellaneous Solids -- Molecular Solids -- Ionic Solids -- Antiferromagnetic Solids -- Metallic Hydrides -- Hexagonal Ice -- Molecules Bound to Surfaces -- H Self-diffusion in Molecular Crystals -- I Ferroelectric Phase Transitions -- 7 Pulsed N.M.R. in Solids -- A Application of Multiple-pulse Experiments to Line-narrowing in Solids -- B Application of Multiple-pulse Experiments to the Study of Molecular Motion -- C Pulsed Double Nuclear Magnetic Resonance Experiments -- Chapter 4 Experimental Techniques -- 1 Introduction -- 2 The Magnet -- A Permanent Magnets -- B Electromagnets -- C Superconducting Magnets -- D Control of Homogeneity -- E Stability. , 3 Sensitivity -- 4 Frequency Generation -- A Single Resonance -- B Double Resonance -- Homonuclear -- Heteronuclear -- Noise -- Universal Shift Reference -- 5 The Probe -- A Single-coil Systems -- B Crossed-coil Systems -- C Double Resonance -- D Field-Frequency Lock -- E General Construction -- F Field Modulation -- G Variable-temperature Operation -- H Rapid Sample Spinning -- 6 The Preamplifier -- 7 The Receiver -- 8 Modulation Schemes -- 9 Computer Techniques -- 10 Pulsed Spectrometers -- 11 Measurement of Relaxation Times -- A Values of T1 -- C.W. Methods -- Pulse Methods -- B Values of T2 -- C.W. Methods -- Pulse Methods -- 12 Miscellaneous Topics -- A Stochastic Resonance -- B Fourier Difference Spectroscopy -- Chapter 5 Spectral Analysis -- 1 New Spin Systems Studied -- Analysis of N.M.R. Spectra of the Type [AMX]2 with J(XX') = 0 -- 2 New Methods of Tackling Known Spin Systems -- A Superoperator Direct Method Least-squares Analysis of N.M.R. Spectra -- B A Systematic Approach to the [AB]2, [AB]2MX, and Derived Systems -- C Use of Double Quantum Transitions -- Double Resonance: Perturbation of Double Quantum Transitions -- Effect of Double Irradiation (Tickling) of Single Quantum Transitions or Double Quantum Transitions in Systems Simplified by Double Resonance -- 3 Studies of Known Spin Systems -- A Systems involving Protons Only -- Aliphatic Systems -- Olefinic Systems -- Heterocyclic Systems -- Aromatic Systems -- B Compounds containing Fluorine -- 2,2'-, 3,3'-, and 4,4'-Dihalogenobiphenyl Compounds ABCD, ABCDX -- Pyridine Compounds -- Pentafluorophenol, (AM)2X -- Benzene, Naphthalene, Phenanthrene, and Biphenyl Compounds -- Tetrafluorodichlorocyclopropanes, [AX]2, A4 -- 1,1,2,2-Tetrafluoroethane [AMX]2 -- C Compounds containing Phosphorus -- Bis(dialkylphosphines) -- The [AMX18]2 System -- Tri-(3-furyl)phosphine, ABCX. , 1-Phospha-2,6-dioxacyclohexanes -- 1-Phospha-2,5-dioxa(diaza, dithia)cyclopentanes -- Bis-(5,5-dimethyl-1-phospha-2-oxo-6-thionocyclo-hexane) -- D Organometallic Compounds -- Triphenyl Group IV Element Lithium Compounds, [AB]2C -- Allenic Derivatives of Tin, Lead, and Mercury AB2X -- Cycloheptatrienyl Manganese Tricarbonyl Compounds, A[BCXY]2, ABCDEXYZ -- Aryl Derivatives of Mercury, [AB]2C, [AB]2X, [AB]2 -- 4 General Comments -- Books and Reviews -- Computer Programs -- Chapter 6 Bandshape Phenomena for Fluids -- 1 General Introduction -- A Current Developments -- B Coverage of the Report -- C Nomenclature, Notation, and Units -- D Reviews and Symposia -- 2 Experimental Features -- Miscellaneous -- 3 Exchange of Magnetic Sites -- A Theoretical Work -- B Examples of Intramolecular Exchange -- Hindered Internal Rotation -- Nitrogen Inversion -- Ring Inversion -- Phosphorus-containing Compounds -- Metal Complexes -- C Examples of Intermolecular Exchange -- Studies of Ligand Exchange (The Swift-Connick Approach) -- Other Studies of Intermolecular Exchange -- 4 Effects of Quadrupolar Nuclei -- A Theoretical Work -- B Resonance of Spin-½ nuclei Coupled to Quadrupolar Nuclei -- C N.M.R. Spectra of Quadrupolar Nuclei -- Nitrogen -- Other Nuclei -- D Effects of Magnetic Site Exchange on N.M.R. Spectra for Spin Systems containing Quadrupolar Nuclei -- 5 Relaxation Effects - Linewidths -- A Theoretical Work -- B Paramagnetic Effects -- C Gas-phase Studies -- D Miscellaneous Width Studies -- 6 Relaxation Effects-Saturation -- 7 Bandshapes in Multiple Resonance -- Cases including Exchange -- Chapter 7 Multiple Resonance -- 1 Introduction -- 2 Theory of Multiple Resonance -- 3 Double Resonance in the Presence of Chemical Exchange -- 4 Chemical Applications of Multiple-resonance Techniques -- Spin Decoupling -- Generalized Overhauser Effect -- INDOR. , Nuclear Overhauser Effect (NOE).
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  • 4
    Online Resource
    Online Resource
    La Vergne :Royal Society of Chemistry, The,
    Keywords: Nuclear magnetic resonance. ; Nuclear spin. ; Magnetic resonance. ; Electronic books.
    Description / Table of Contents: For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage.
    Type of Medium: Online Resource
    Pages: 1 online resource (458 pages)
    Edition: 1st ed.
    ISBN: 9781847553591
    Series Statement: Issn Series
    DDC: 016.538362;538.3;538/.3
    Language: English
    Note: NM9780851862729-FX001 -- NM9780851862729-FP001 -- NM9780851862729-FP003 -- NM9780851862729-FP005 -- NM9780851862729-FP017 -- NM9780851862729-FP023 -- NM9780851862729-00001 -- NM9780851862729-00050 -- NM9780851862729-00106 -- NM9780851862729-00156 -- NM9780851862729-00181 -- NM9780851862729-00223 -- NM9780851862729-00249 -- NM9780851862729-00279 -- NM9780851862729-00311 -- NM9780851862729-00342 -- NM9780851862729-00368 -- NM9780851862729-00378 -- NM9780851862729-00408.
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  • 5
    Online Resource
    Online Resource
    La Vergne :Royal Society of Chemistry, The,
    Keywords: Nuclear magnetic resonance - Collected works. ; Electronic books.
    Description / Table of Contents: For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage.
    Type of Medium: Online Resource
    Pages: 1 online resource (440 pages)
    Edition: 1st ed.
    ISBN: 9781847553584
    Series Statement: Issn Series
    DDC: 016.538362
    Language: English
    Note: Nuclear Magnetic Resonance -- Contents -- Chapter 1 Nuclear Shielding -- 1 Introduction -- 2 Basic Aspects of Nuclear Shielding -- A General Theory -- B Basic Physical Aspects -- 3 Calculations of Nuclear Shielding -- 4 Transmission of Shielding Effects within Molecules -- A Introduction -- B Inductive Effects -- C Resonance Effects -- D Magnetic Anisotropy Effects -- E Electric Field Effects -- F The Ring-current Effect -- G Van der Waals and Steric Effects -- H Intramolecular Hydrogen Bonding -- I Isotope Shifts -- 5 Shieldings of Particular Nuclear Species -- A Introduction -- B Carbon Chemical Shifts -- C Fluorine Chemical Shifts -- D Phosphorus Chemical Shifts -- E Nitrogen Chemical Shifts -- F Chemical Shifts of Nuclei Other than H,C,F,P, and N -- 6 Chemical Shift Anisotropy -- Chapter 2 Nuclear Spin-Spin Coupling -- 1 Introduction -- 2 Basic Theory: Notation and Abbreviations -- A Sum-Over-States Perturbation Theory (SOS) -- B Finite Perturbation Theory (FPT) -- C Semi-empirical Molecular Orbital Methods -- D Units -- 3 Theoretical Work -- A Calculations on H2 or HD -- B Ab Initio Calculations of Coupling in Small Molecules -- C Semi-empirical Calculations -- D π-Electron Coupling -- E Nuclear-spin and Electron-spin Coupling -- F Solvent Effects -- 4 Coupling of Directly Bonded Nuclei -- A Coupling in HD -- B Coupling between 13C and 1H -- C Coupling between 15N and 1H -- D Coupling between 31P and 1H -- E Coupling between 1H and Other Nuclei -- F 1J(13C,13C), 1J(l3C,15N), 1(11B,13C), and 1J(11B,11B) -- G Coupling between 13C and 31P -- H Coupling between 13C and 19F -- I Coupling between 13C and Metals -- J Coupling to 19F, except 1J(19F,31P) and 1J(19F,13C) -- K Coupling between 31P and 19F -- L Other One-Bond Couplings involving 31P -- 5 Coupling between Nuclei Separated by Two Chemical Bonds, 2J. , A Geminal Proton-Proton Coupling across Carbon -- B Geminal Proton-Proton Coupling across Other Elements -- C 2J(13CC1H) -- D Coupling of Other Nuclei to Protons via Carbon, 2J(XC1H) -- (i) X = 199Hg -- (ii) X = 11B and 27A1 -- (iii) X = 73Ge, 119,117Sn, and 207Pb -- (iv) X = 15,14N and 31P -- (v) X = 77Se -- (vi) X = 19F -- (vii)X = 183W and 19SPt -- E 2J(19FC19F) -- F 2J(13CC13C), 2J(31PC13C), and 2J(15NC13C) -- G 2J(31PN13C) and 2/(31PN31P) -- H 2J(31PM13C), where M is a metal -- I 2J(31PM31P), where M is a Metal -- J 2J(13CO13C) and 2J(31PO13C) -- K Other Two-bond Coupling Constants -- 6 Coupling between Nuclei Separated by Three Chemical Bonds, 3J -- A Coupling of Protons via Two Carbon Atoms -- B Three-bond Coupling of Protons via Other Atoms -- C Three-bond Coupling of Carbon to Protons -- D Three-bond Coupling of Other Nuclei to Protons via Two Carbon Atoms, 3J(XCC1H) -- (i) X = 15,14N -- (ii) X = 11B and 27A1 -- E Three-bond Coupling to Fluorine via Two Carbon Atoms, 3J(XCC19F) -- (i) X = 1H -- (ii) X = 19F -- (iii) X = 15N and 199Hg -- F Three-bond Couplings between Phosphorus and Hydrogen, 3J(31PXC1H) -- (i) X = O -- (ii) X = N -- (iii) X = S -- (iv) X = a Group IVB Element -- (v) X = Au and Pt -- G 3J(13CCC31P) and 3/(13CC031P) -- H 3J(13CCC13C) -- I 3J(199HgXC1H) -- J 3J(195PtXC1H), X = N, P, and As -- K Other Three-bond Coupling Constants -- 7 Coupling between Nuclei Separated by Four Chemical Bonds, 4J -- A 4J(1HCCC1H) -- B Other Four-bond (H,H) Couplings -- C Four-bond Coupling of 13C, 14N, and 31P to 1H via Carbon Atoms -- D Four-bond Coupling of Metals to Protons -- E 4J(1HCCC19F) and 4J(19FCCC19F) -- F Other Four-bond Couplings -- 8 Coupling between Nuclei Separated by Five Chemical Bonds, 5J -- A 5J(1HCCCC1H) -- B 5J(1HCCXC1H), X = N, O, and S -- C Five-bond Coupling of 1H to 19F -- D Other Five-bond Couplings. , 9 Coupling between Nuclei Separated by Six or More Chemical Bonds -- A 6J -- B 7J and 8J -- 10 Coupling in Aromatic Systems -- A (1H,1H) Coupling in Benzenoid Aromatic Systems -- B (1H,1H) Coupling in Heteroaromatic Systems -- C Coupling in Metal-Cyclopentadienyl Compounds -- D (1H,19F) Coupling in Aromatic Systems -- E (1H,13C) Coupling in Aromatic Systems -- F (1H,31P) Coupling in Aromatic Systems -- G Coupling of Protons to Other Nuclei in Aromatic Systems -- H (13C,15N) Coupling in Aromatic Systems -- I Other Couplings in Aromatic Systems -- 11 'Through-space' Coupling -- 12 Isotope Effects -- 13 Experimental Work of Significance for the Measurement or Interpretation of Spin-Spin Coupling Constants -- A Multiple-resonance Experiments -- B Bandshape Analyses -- C Effects of Paramagnetic Materials -- D Fourier-transform Experiments -- E Other Experimental Techniques -- Chapter 3 Nuclear Spin Relaxation -- 1 Introduction -- 2 Spin Relaxation in Gases -- A Introduction -- B Theoretical Developments -- C Diatomic Molecules -- D Polyatomic Molecules -- E Spin Diffusion Measurements -- 3 Spin Relaxation in Liquids -- A Introduction -- B Pure Liquids -- Linear Molecules -- Spherically Symmetric Molecules -- Axially Symmetric Molecules -- Asymmetric Molecules -- C Internal Rotation of Methyl Groups -- D Molecular Motion and Association in Mixtures of Liquids -- Molecular Rotation Studies -- Molecular Association Studies -- Aqueous Solutions of Non-electrolytes -- Hydrogen-bonded Systems -- E Ionic Solutions -- Diamagnetic Solutions -- Paramagnetic Solutions -- F Relaxation by Translational Diffusion -- G Spin-diffusion Measurements in Liquids -- H Transverse Relaxation and Spin-echo Studies -- Spin-echo Spectroscopy -- Selective Measurement of Transverse Relaxation Rates -- Chemical Exchange Studies -- I Models for Molecular Rotation. , J Studies of Critical Phenomena in Fluids -- K 13C Relaxation Studies -- Small Molecules -- Complex Molecules -- L 15N Relaxation Studies -- M 31P Relaxation Studies -- N Determination of Spin Interaction Constants from Spin-Relaxation Measurements -- Scalar Spin-Spin Coupling Constants -- Nuclear Quadrupole Coupling Constants -- Spin-Rotation Interaction Constants and Chemical Shielding Anisotropics -- O Miscellaneous Papers -- 4 Spin Relaxation in Liquid Crystals -- A Nematic Phases -- B Cholesteric Phases -- C Isotropic Phases -- D Spin-diffusion Studies -- 5 Spin Relaxation in Solids -- A Spin-Lattice Relaxation in the Rotating Frame and Dipolar Relaxation -- B Spin-Lattice Relaxation by Anisotropic Chemical Shielding Interaction -- C Spin-Lattice Relaxation by Spin-Rotation Interaction -- D Spin-Lattice Relaxation by Nuclear Quadrupole Interaction -- E Spin-Lattice Relaxation due to Paramagnetic Impurities -- F Investigations of Molecular Reorientation -- Molecular Solids -- Internal Rotation in Molecular Solids -- Internal Rotation in Ionic Solids -- Spin-Lattice Relaxation by Quantum Mechanical Rotation at Low Temperatures -- G Investigations of Self-diffusion -- General Developments -- Metals -- Metal Hydrides -- Ionic Crystals -- Molecular Crystals -- H Studies of Molecules Bound to Solid Surfaces -- I Ferroelectric Materials -- Chapter 4 Experimental Techniques -- 1 Introduction -- 2 Probes -- A Variable Temperature -- B High Pressure -- C High Field -- 3 Frequency Generation -- 4 Pulse-sequence Generation -- 5 Continuous-wave Spectroscopy -- A Double-resonance Techniques -- B 'Other' Nuclei -- C Use of Computers -- D Relaxation Measurements -- 6 High-resolution Fourier-transform Spectroscopy -- A Introduction -- B Fourier Spectrometers -- C Relaxation Measurements -- T1 -- Spin Echoes -- D Gated Double Resonance. , E Difference Spectroscopy -- 7 General Pulsed Spectroscopy -- A Introduction -- B Spectrometers -- C Relaxation Measurements in Liquids -- T1ρ -- Spin Echoes -- T1 -- D High-resolution Studies in Solids -- Chapter 5 Spectral Analysis -- 1 Introduction -- 2 New Methods of Studying Known Spin Systems -- A Proton Spin-echo N.M.R. Spectra of 2,2-Dichloro-1,1-difluoroethane: Sub-spectral Analysis -- B Spin Hamiltonian for Twofold Symmetry -- Matrix Elements of the Hamiltonian with Symmetrized Spin Operators -- Symmetry Properties of the | A,M > -- Basis Functions -- C Double-quantum Effects in the Spectrum of 2-Bromothiazole -- D The Direct Method Applied to Nuclear Magnetic Double Resonance -- 3 Known Spin Systems -- A AB-Based N.M.R. Systems: Choice of Bounds for θ in Trigonometric Forms of Co-factors in Mixed Wave-functions -- B Systems involving Protons Only -- Saturated Acyclic Systems -- (i) n-Propyl derivatives -- [AB]2C3 -- (ii) 2,2'-Dihalogenodiethyl ethers -- [AB]2 -- Saturated Cyclic Systems -- (i) 1,3-Dioxans -- AB, AMX, ABX, [AX]2 -- (ii) D-Aldopentapyranosyl derivatives -- ABX -- (iii) N-Substituted styreneimines -- ABX -- (iv) L-Azetidine-2-carboxylic acid (L-ACA) and N-acetyl-L-azetidine-2-carboxylic acid (N-A-L-ACA) -- ABCDE -- (v) 1,2,3-Substituted prolines -- ABCDEF -- Olefinic Compounds: Dichloropentenes -- ABCDE -- Unsaturated Five-membered Ring Compounds -- (i) 3,5-Disubstituted 1,2-dihydro-furans and -thiophens -- ABX, ABXY3, ABXY2, ABC -- (ii) Dimers of cyclopentadienyl compounds -- Sesquiterpenoids -- ABX{H} -- Aromatic Systems -- Aromatic substitution patterns -- Biologically important aromatic acids -- Benzocycloheptenes -- Carbanions and Ion Pairing -- [AM]2X, AMRX, [AX]2, AA'X -- Aryldi-t-butylmethanol -- Acridine and Five Monomethyl Derivatives -- 'ABCDX' -- Sulphur Heterocycles -- syn- and anti-2-Furanaldoximes. , C Compounds containing Fluorine.
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  • 6
    Online Resource
    Online Resource
    La Vergne :Royal Society of Chemistry, The,
    Keywords: Nuclear magnetic resonance - Collected works. ; Electronic books.
    Description / Table of Contents: For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage.
    Type of Medium: Online Resource
    Pages: 1 online resource (374 pages)
    Edition: 1st ed.
    ISBN: 9781847553614
    Series Statement: Issn Series
    DDC: 016.538362
    Language: English
    Note: Nuclear Magnetic Resonance -- Contents -- Chapter 1 Nuclear Shielding -- 1 Introduction -- 2 Basic Aspects of Nuclear Shielding -- A General Theory -- B Basic Physical Aspects -- 3 Calculations of Nuclear Shielding -- 4 Transmission of Shielding Effects within Molecules -- A Introduction -- B Inductive, Resonance, and General Substituent Effects -- C Electric Field Effects -- D Magnetic Anisotropy Effects -- E Ring-current Effects -- F van der Waals and Steric Effects -- G Intramolecular Hydrogen Bonding -- H Isotope Effects -- I Chemical Shift Anisotropy -- 5 Shieldings of Particular Nuclear Species -- A Introduction -- B Carbon Chemical Shifts -- C Fluorine Chemical Shifts -- D Phosphorus Chemical Shifts -- E Chemical Shifts of other Nuclei -- Chapter 2 Nuclear Spin-Spin Coupling -- 1 Introduction -- 2 Theoretical Work -- A Ab Initio Calculations -- B Semi-Empirical Calculations (Excluding Those on π-Electron Systems) -- C Semi-Empirical Calculations on π-Electron Systems -- D Calculations of Through-space Coupling -- E Other Topics of Theoretical Interest -- 3 Coupling of Directly-bonded Nuclei -- A Coupling to Hydrogen -- B Coupling to Elements of Groups IIIB and IVB -- C Coupling to Elements of Group VB -- D Coupling to Elements of Group VIB -- E Coupling to Elements of Group VIIB -- F Miscellaneous One-bond Couplings -- 4 Coupling between Nuclei Separated by Two Chemical Bonds, 2J -- A Geminal Proton-Proton Coupling -- B Two-bond Coupling of Other Nuclei to Protons -- C Two-bond Coupling to Carbon [Excluding 2J(13CXlH)] -- D Two-bond Coupling to Group VB Atoms -- E 2J(31PC19F) -- F Two-bond (19F,19F) Coupling -- G Miscellaneous Two-bond Couplings -- 5 Coupling between Nuclei Separated by Three Chemical Bonds, 3J -- A Vicinal Proton-Proton Coupling via Carbon, 2J(1HCC1H) -- B Three-bond Coupling of Protons via Other Atoms. , C Three-bond Coupling of Other Nuclei to Protons -- D Three-bond Coupling to Carbon -- E Three-bond Coupling to Phosphorus -- F Three-bond Coupling to Fluorine -- 6 Coupling between Nuclei Separated by Four Chemical Bonds, 4J -- A Proton-Proton Coupling via Carbon, 4J(1HCCC1H) -- B Four-bond Coupling of Protons via Other Atoms -- C Four-bond Coupling of Other Nuclei to Protons -- D Four-bond Coupling to Carbon -- E Four-bond Coupling to Fluorine -- 7 Coupling between Nuclei Separated by Five Chemical Bonds, 5J -- A Proton-Proton Coupling via Carbon, 5J(1HCCCC1H) -- B Five-bond Proton-Proton Coupling via Other Atoms -- C Five-bond Coupling of Other Nuclei to Protons -- D Five-bond Coupling to Carbon -- E Five-bond Coupling to Fluorine -- 8 Coupling between Nuclei Separated by Six Chemical Bonds, 6J -- 9 Coupling between Nuclei Separated by Seven Chemical Bonds, 7J -- 10 Coupling in π-Electron Systems -- A Homoaromatic Molecules -- B Heterocyclic Molecules -- C Annulenes -- D Linear Conjugated Systems -- 11 Through-space Coupling -- 12 Recent Experimental Advances -- Chapter 3 Nuclear Spin Relaxation in Fluids -- 1 Introduction -- 2 Theoretical Work -- 3 Relaxation Studies in Pure Liquids -- A Proton and Deuteron Relaxation -- B 13C Relaxation -- C Relaxation of Other Nuclei: 14N, 15N, 17O, 19F, 29Si, 77Se -- D Studies of Several Resonant Nuclei: 2H, 13C, 14N, 15N, ,19F -- 4 Relaxation Studies in Liquid Mixtures of Non-electrolytes -- A Proton and Deuteron Relaxation -- B 13C Relaxation -- C Studies of Several Resonant Nuclei: !H, 2H, 13C, 14N -- 5 Relaxation Studies in Electrolyte Solutions -- A Proton and Deuteron Relaxation -- B Relaxation of the Nuclei: 13C, 17O, 69Ga, 71Ga, 113Cd -- C Relaxation of Alkali-metal and Halogen Nuclei: 7Li, 23Na, 39K, 41K, 87Rb, 133Cs, 35C1, 79Br, 81Br -- 6 Relaxation Studies in Gas-Liquid Solutions. , 7 Relaxation Studies of Gases -- A Theoretical Work -- B Mono- and Di-atomic Gases -- C Polyatomic Gases -- Chapter 4 Experimental Techniques -- 1 Introduction -- 2 Diverse Applications of N.M.R. -- A General -- B Neutron Resonance and Diffraction -- C Image Formation by Zeugmatography -- 3 Temperature and Pressure Studies -- 4 Measurement of Relaxation Times -- A Systematic Errors -- B Quantization and Other Errors -- C Technique -- 5 Broad-line and Solid-state Spectroscopy -- 6 Instrumentation -- A Signal Processing -- B The Probe Area -- C The Transmitter -- D Modulation Control -- E Complete Spectrometers -- F Modification of Commercial Instruments -- 7 Miscellaneous -- Chapter 5 Spectral Analysis -- 1 Introduction -- 2 New Approaches to Known Spin Systems -- A [A]2X and ABX Systems -- B [AB]2 Systems. -- C The X-{A} indor Spectrum of the [AXn]2 Spin System -- D [[A]2Xn]2 and [ABXn]2 Spin Systems, with n = 1, 2 or 3 -- 3 More Examples of Known Spin Systems -- A Three-spin systems -- B Four-spin systems -- C Five-spin systems -- D Six-spin systems -- E Seven-spin systems -- F Eight-spin systems -- G Spin systems of nine nuclei or more -- 4 Conclusions -- Chapter 6 Bandshape Phenomena in Liquids -- 1 Introduction -- 2 General Theory -- 3 Exchange of Magnetic Sites -- A General Theory -- B Intramolecular Exchange Processes in Organic Molecules -- C Complex Rearrangements -- D Intermolecular Exchange Processes -- E Biochemical Applications -- 4 Relaxation Effects: Linewidths -- A Chemical Exchange Rates Determined by the Swift-Connick Approach -- B Linewidth Determinations in Paramagnetic Systems -- Chapter 7 Fourier Transform N.M.R. -- 1 Introduction -- 2 New Applications -- 3 Instrumentation -- A Multinuclear Spectrometers -- B Quadrature Phase Detection (QPD) -- C Solvent Elimination -- 4 Computer Simulation of Pulsed N.M.R. , A Multipulse Experiments -- B Diffusion and Field Gradient Effects -- 5 The Equivalence of Fourier and Continuous Wave Spectra -- 6 Correlation Spectroscopy -- 7 Hadamard Spectroscopy -- 8 Double Resonance in FT N.M.R. -- 9 The Measurement of Relaxation Times -- 10 Miscellaneous -- Chapter 8 Macromolecules -- 1 Introduction -- 2 Reviews -- 3 Synthetic Macromolecules -- A High-resolution 1H N.M.R. -- B Broadline N.M.R. -- C Spin-echo N.M.R. -- D 13C N.M.R. -- E Other Nuclei -- 4 Biological and Related Macromolecules -- A 1H N.M.R. of Synthetic Polypeptides -- B 1H N.M.R. of Proteins -- C 1H N.M.R. of Enzymes -- D 1H N.M.R. of Natural and Related Polypeptides and Polysaccharides -- E 1H N.M.R. of Polynucleotides -- F 13C N.M.R. -- G Other Nuclei -- 5 Small Molecules -- A 1H N.M.R.: Hydration -- B 1H N.M.R.: General Studies -- C 13C N.M.R. Studies -- D Other Nuclei -- Chapter 9 The Solid State -- 1 General Introduction -- 2 Half-integral Spins in Diamagnetic Solids -- A Introduction -- B Theoretical Aspects -- C Structural Studies (Broadline Techniques) -- D High Resolution in Solids -- E Motional Studies (Classical Regime) -- F Quantum Effects in Molecular Solids -- G N.M.R. Studies of Helium -- 3 Nuclei of Spin > -- 1/2 in Diamagnetic Solids -- A Introduction -- B 2H N.M.R. -- C The Halogen Nuclei -- D The Alkali-metal Nuclei -- E Transition-element Nuclei -- F Other Nuclei -- 4 Systems with Unpaired Electrons in the Absence of Magnetic Ordering -- A Non-metallic Paramagnetic Systems -- B Metals -- C Alloys and Intermetallic Systems -- D Hydrides -- E Semiconductors -- F One-dimensional Conductors -- 5 Ordered Magnetic Materials -- A Ferromagnetic Materials -- B Antiferromagnetic Materials -- C Ferrimagnetic Materials -- 6 New Techniques and Apparatus -- A Techniques -- B Data Analysis -- C Apparatus -- Chapter 10 Heterogeneous Systems. , 1 Introduction -- 2 Adsorption Studies -- A General -- B Cryogenic Studies -- C Zeolites -- 3 Polymers, Exchange Resins, and Gels -- 4 Protein Hydration -- 5 Cellular Systems -- 6 Membranes -- 7 Micellar Systems -- Chapter 11 Medium Effects on Chemical Shifts and Coupling Constants -- 1 Introduction -- 2 Non-specific Solvent Effects -- 3 Specific interactions with the Medium -- A General -- B Solvent Effects on Conformational Equilibria -- C The ASIS Effect -- D Hydrogen Bonding -- E Ionic Solutions -- F Micellar Systems -- 4 Shift Reagents -- A General -- B The Stoicheiometry of the Shift-reagent-Substrate Complex -- C Dipolar, Contact, and Complexation Shifts -- D Calculation of the Substrate-Shift Reagent Complex Geometry -- E Structural Assignments -- F Preferred Binding Sites -- Chapter 12 Oriented Molecules -- 1 Introduction -- 2 Structure Determination -- A Structures of Rigid Molecules -- B Corrections for Vibrational Motion -- C Molecules with Internal Motion -- 3 Determination of Indirect Couplings -- 4 Double-resonance Techniques -- 5 Order Parameters -- 6 Anisotropies in Indirect Couplings -- 7 Anisotropies in Chemical Shifts -- 8 Nuclear Quadrupole Coupling Constants -- Author Index.
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  • 7
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Serotonin. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (289 pages)
    Edition: 1st ed.
    ISBN: 9780080460765
    Series Statement: Issn Series
    Language: English
    Note: front cover -- copyright -- table of contents -- Preface -- SECTION I THE CHOLINERGIC SYSTEM -- PART I. INTRODUCTION -- I. Anatomy -- PART II. THE MUSCARINIC SYSTEM -- I. Anatomy -- II. Electrical Activity -- III. Interactions with Other Transmitters -- IV. Postsynaptic Cascades -- V. Other Topics -- PART III. THE NICOTINIC SYSTEM -- I. Microanatomy -- II. Functional Microanatomy -- III. Interactions with Other Transmitters -- IV. Learning -- V. Miscellaneous Topics -- Section I References -- Section I Further Reading -- SECTION II THE DOPAMINE SYSTEM -- Section II Further Reading -- Section II References -- IX. Miscellaneous Items -- VIII. Parkinson's Disease -- VII. Dopamine and Behavior -- VI. Dopamine and Learning -- V. Miscellaneous Items -- IV. Dopamine-Induced Signaling Cascades -- III. Interaction between Dopamine and other Transmitters -- II. Electrical Reactions -- I. Anatomy -- SECTION III THE NOREPINEPHRINE SYSTEM -- Section III Further Reading -- Section III References -- VIII. Miscellaneous Items -- VII. Memory and Learning (LTP) -- VI. Tropins and Cytokines -- V. Postsynaptic Cascades -- IV. Interactions with Other Transmitters -- III. Electrical Activity -- II. Functional Neuroanatomy -- I. Microanatomy -- SECTION IV THE ADRENALINE SYSTEM -- Section IV References -- SECTION V SEROTONIN SYSTEM -- Section V Further Readings -- Section V References -- VIII. Miscellaneous -- VII. Sleep -- VI. Serotonin and the Development of Neural Systems -- V. Serotonin and Synaptic Plasticity -- IV. Postsynaptic Cascades -- III. Interactions Between Serotonin and Other Neurotransmitter Systems -- II. Electrical Actions -- I. Anatomy -- SECTION VI CONCLUSION -- Section VI References -- Possibly Obscure Acronyms for some Readers -- index.
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  • 8
    Online Resource
    Online Resource
    La Vergne :Royal Society of Chemistry, The,
    Keywords: Organometallic compounds - Collected works. ; Electronic books.
    Description / Table of Contents: This Specialist Periodical Report aims to reflect the growing interest in the potential of organometallic chemistry.
    Type of Medium: Online Resource
    Pages: 1 online resource (539 pages)
    Edition: 1st ed.
    ISBN: 9781847553911
    Series Statement: Issn Series
    DDC: 547.05
    Language: English
    Note: Organometallic Chemistry -- Contents -- Chapter 1 Group I. The Alkali and Coinage Metals -- 1 Lithium -- Structural and Bonding Studies -- Polylithio-compounds -- Halogenocarbon Derivatives -- Some Organic Reactions -- 2 Sodium and Potassium -- 3 Copper, Silver, and Gold -- Copper and Silver π-Complexes -- σ-Bonded Organo-copper and -silver Compounds -- Gold -- Chapter 2 Group II. The Alkaline Earths and Zinc and its Congeners -- 1 Beryllium -- 2 Magnesium -- Preparation and Composition -- Reactions -- Inversions and Rearrangements -- Halogenocarbon Derivatives -- 3 Calcium, Strontium, and Barium -- 4 Zinc and Cadmium -- 5 Mercury -- Preparative Reactions -- Mercuration and Demercuration Reactions -- Other Reactions -- Carbene Precursors -- Chapter 3 Group III. Boron, Aluminium, Gallium, Indium, and Thallium -- 1 Introduction -- 2 Boron -- General -- Preparations -- Radical Reactions -- Mechanisms and Kinetics -- Preparative Reactions involving Radicals -- Non-radical Mechanisms and Kinetics -- Nucleophilic Displacements at Tetrahedral Boron Centres -- Displacement of the Alkyl Groups attached to Boranes -- Olefin Elimination and Addition -- Reactions of R3B -- Organic Reactions of R3B -- Hydrido-organoboranes -- Compounds containing Boron-Nitrogen Bonds -- Borinic and Boronic Acids and their Derivatives -- Synthesis -- Reactions -- Compounds containing Boron-Chalcogen Bonds -- Compounds containing Boron-Halogen Bonds -- 3 Aluminium -- Preparations and Reactions -- Structures, Bonding, and Exchange Reactions -- Organic Applications -- Mechanisms and Kinetics -- Various Reactions -- Transition-metal-Organoaluminium Systems -- 4 Gallium -- 5 Indium -- 6 Thallium -- Trialkylthalliums-R3T1 -- Dialkylthallium and Diarylthallium Compounds-R2T1X -- Monoalkylthallium and Monoarylthallium Compounds-RT1X2 -- Organic Reactions. , Thallium(i) Cyclopentadienides -- Chapter 4 Group III. The Carboranes -- Chapter 5 Group IV. The Silicon Group -- 1 Introduction -- 2 Formation of the Carbon-Metal Bond Synthesis -- Reactions of M-C Compounds -- 3 Cleavage of the Carbon-Metal Bond -- 4 Mechanistic Studies of Carbon-Metal Bond Cleavage -- Rearrangement Reactions involving the Silicon-Carbon Bond -- 5 Thermochemical, Spectroscopic, and Structural Studies -- 6 Cyclopentadienyl Derivatives of the Group IV Elements -- 7 Addition Reactions -- 8 Alkali-metal Derivatives R3MM' -- 9 Catenation -- 10 Carbenes and their Silicon Group Congeners -- 11 Mercury Derivatives -- 12 Free Radicals -- 13 Hydrides of Silicon and Germanium -- 14 Organotin Hydrides -- 15 Boron Derivatives -- 16 Nitrogen Derivatives -- Diazo-compounds -- Azides -- Addition Reactions -- Silazanes -- Aminosilanes -- 17 Phosphine, Arsine, and Stibine Derivatives -- 18 Silicon-Oxygen Compounds -- Alkoxysilanes and Siloxanes -- Rearrangements involving Compounds containing the Si-O Bond -- Silyl Esters -- Organosilicon Peroxides -- 19 Germanium-Oxygen Compounds -- 20 Tin-Oxygen Compounds -- 21 Sulphur Derivatives -- 22 Lead-Oxygen and Lead-Halogen Compounds -- 23 Halogen Exchange Reactions -- 24 Complexes of Silicon, Germanium, Tin, and Lead -- 25 Structural Determinations -- 26 Bonding in Group IV Organometallic Compounds -- Chapter 6 Metal Carbonyls -- 1 Introduction -- 2 Spectroscopic Studies -- 3 Preparation of Carbonyl Compounds -- 4 Hydrido(carbonyl)metal Complexes -- 5 Halogeno- and Azido-(carbonyl)metal Complexes -- Chapter 7 Organometallic Compounds containing Metal-Metal Bonds -- 1 Introduction -- 2 Compounds containing Transition Metal-Transition Metal Bonds -- Compounds containing Isolated Bonds and Bond Sequences -- Transition Metal Clusters. , 3 Compounds containing Bonds between Transition Metals and the Elements of Groups IB-VB -- Group IB -- Group IIB -- Group IIIB -- Boron -- Aluminium -- Indium and Thallium -- Group IV -- General Preparative Work -- The Nature of the Metal-Metal Bond -- Titanium Group -- Chromium Group -- Manganese Group -- Iron Group -- Cobalt Group -- Nickel Group -- Group V -- 4 Compounds containing Group IIB-Group IV Element Bonds -- Chapter 8 Substitution Reactions of Metal and Organo-metal Carbonyls with Group V and VI Donor Ligands -- 1 Introduction -- 2 General Papers on Metal Carbonyl Complexes -- 3 Group V -- 4 Group VI -- Complexes of Cr°, Mo° and W° -- Halogenocarbonyl Complexes of and IIMo WII -- Cyclopentadienyl Carbonyl Complexes of MoII and WII -- 5 Group VII -- Complexes of Mn° and Re0 -- Cyclopentadienyl Carbonyl Complexes of MnI -- Other Complexes of MnI and ReI -- 6 Group VIII: Fe, Ru, and Os -- Complexes of the Cluster Carbonyls -- Mononuclear Complexes of Fe° and Ru° -- Complexes containing the M2(CO)6 Unit (M = Fe or Ru) -- Cyclopentadienyl Carbonyl Complexes of FeII -- Other Complexes of FeII, RuII, and OsII -- 7 Group VIII: Co, Rh, and Ir -- Complexes of Co0, Rh°, and Ir° -- Complexes of Co1, Rh1, and Ir1 -- 8 Group VIII: Ni, Pd, and Pt -- 9 Copper -- Chapter 9 Carbene, Nitrene, and Related Complexes -- 1 Synthesis of Carbene Complexes -- 2 Structure and Bonding in Carbene Complexes -- 3 Reactions of Carbene Complexes -- 4 Nitrene Complexes -- Chapter 10 Complexes containing Metal-Carbon σ-Bonds -- 1 σ-Bonded Complexes -- Group IV -- Group V -- Group VI -- Group VII -- Group VIII -- Group I -- 2 Compounds Derived from Carbonylmetal Anions -- 3 Insertion Reactions -- Carbon Monoxide (and Decarbonylation Reactions) -- Sulphur Dioxide -- Olefins and Acetylenes -- Tetracyanoethylene -- Isocyanides -- 4 ortho-Metallation and Related Reactions. , Nitrogen Donors -- Phosphorus Donors -- Carbon Donors -- Sulphur Ligands -- 5 Formation of M-C σ-Bonds from Olefin or Diene Complexes -- 6 Cobaloximes, Cobalamins, and Related Compounds -- 7 Organic Derivatives of Schiff-base Complexes -- Chapter 11 Hydrocarbon-Metal π-Complexes -- 1 Bonding in Mono-olefin and Acetylene Complexes -- 2 Mono-olefin Complexes -- 3 Mono-olefin Chelate Complexes -- 4 Acetylene Complexes -- 5 Acyclic Conjugated Diolefin Complexes -- 6 Cyclic Conjugated Diolefin Complexes -- Cyclobutadiene Complexes -- Cyclopentadiene Complexes -- Complexes of Six- and Seven-membered Rings -- Complexes of Eight-membered Rings -- 7 Complexes of Chelating Unconjugated Diolefins -- 8 Cationic Metal-Olefin and -Acetylene Complexes -- 9 Complexes Derived from Allenes and from Trimethyl-enemethane -- 10 Complexes of Polycyclic Hydrocarbons -- Chapter 12 π-Allylic Complexes -- 1 General Developments -- 2 Tantalum -- 3 Iron, Ruthenium, and Osmium -- 4 Cobalt, Rhodium, and Iridium -- 5 Nickel, Palladium, and Platinum -- Chapter 13 π-Cyclopentadlenyl, Arene, and Related Compounds -- 1 Introduction -- 2 π-Cyclopentadienyl Complexes -- Features of General Interest -- Group IV -- Preparation of Complexes -- Other Studies -- Group V -- Group VI -- Preparation of Complexes -- Other Studies -- Group VII -- Group VIII: Fe, Ru, and Os -- Preparation of Complexes -- Other Studies -- Group VIII: Co, Rh, and Ir -- Group VIII: Ni, Pd, and Pt -- Preparation of Complexes -- Other Studies -- Other Metals -- 3 π-Arene Complexes -- Group VI -- Preparation of Complexes -- Other Studies -- Group VII -- Group VIII: Fe, Ru, and Os -- Group VIII: Co, Rh, and Ir -- Group VIII: Ni -- Uranium -- 4 Carborane Complexes -- The [B9C211]2- Ligand and Related Systems -- Other Carborane Ligands -- Theory of Bonding in Carborane Complexes -- 5 Complexes with Other Related Ligands. , Tris(pyrazolyl)borate Complexes -- Borabenzene Complexes -- Borazole Complexes -- Pyrrole and Pyrrolyl Complexes -- Thiophen Complexes -- Chapter 14 Substitution Reactions of Hydrocarbon-Metal π-Complexes -- 1 Introduction -- 2 Results of General Interest -- 3 Individual Systems -- OC6H6)Cr(CO)3 (Benchrotrene) -- [(Tropylium)Cr(CO)3]+ and Related Complexes -- (π-C5H5)Mn(CO)3 (Cymantrene) -- (π-C4H4)Fe(CO)3 -- (π-Diene)Fe(CO)3 Complexes -- [(π-C5H5)Fe(π-C6H6)]+ Complexes -- (π-CsHs)2Co and Derived (π-C5H5)Co(π-diene) Complexes -- Cobalt-Carbon Cluster Compounds -- 4 Chemistry of the Iron-group Metallocenes (Ferrocene, Ruthenocene, and Osmocene) -- General -- General Chemistry -- Proton N.M.R. Studies -- Stereochemistry of Ferrocenes -- Biferrocenyls and Bridged Ferrocenes (Ferro-cenophanes) -- Polymeric Ferrocene Derivatives -- Ferrocene Derivatives containing Heteroatoms -- Boron -- Silicon and Germanium -- Phosphorus and Arsenic -- Sulphur -- Transition Metals -- Ferricinium Salts -- Chapter 15 Oxidative-addition and Related Reactions -- 1 Niobium and Tantalum -- 2 Chromium, Molybdenum, and Tungsten -- 3 Iron, Ruthenium, and Osmium -- 4 Cobalt, Rhodium, and Iridium -- 5 Nickel, Palladium, and Platinum -- Chapter 16 Homogeneous Catalysis -- 1 General -- 2 Hydrogenation -- 3 Isomerization -- 4 Skeletal Rearrangements -- 5 Rearrangement of Strained Cycloalkanes -- 6 Hydroformylation and Related Reactions -- 7 Dimerization and Oligomerization -- 8 Oxidation -- 9 Synthesis -- Reduction of Dinitrogen -- Chapter 17 X-Ray and Electron Diffraction Studies of Organometallic Compounds -- 1 Introduction -- Coverage -- Symbols, Abbreviations, and Conventions -- 2 Main Table Listing Compounds and Structural Data -- 3 Cross-reference Lists -- Metal Listings -- Ligand Listings -- Author Index.
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  • 9
    Publication Date: 2018-02-16
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 10
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: High-mobility group box chromosomal protein 1 (HMGB1) is a protein with both intranuclear functions and extracellular cytokine-like effects. In this report, we study possible candidate receptors for HMGB1 on macrophages (Mφ) and define pathways activated by HMGB1 binding. Bone marrow Mφ were prepared from Dark Agouti (DA) rats and stimulated in vitro with HMGB1. The kinetics of tumour necrosis factor (TNF) production, NO production, activation of p38 mitogen-activated protein kinase (MAPK), p44/42 MAPK- and SAPK/JNK-signalling pathways, nuclear translocation of nuclear factor kappa B (NF-κB) and HMGB1-induced upregulation of major histocompatibility complex (MHC) class II and CD86 were analysed. Mφ from interleukin (IL)-1 receptor type I–/–, Toll-like receptor 2 (TLR2–/–) and RAGE–/– mice were used to investigate the role of these receptors in HMGB1 signalling. HMGB1 induced TNF and NO production by Mφ, phosphorylation of all investigated MAP kinase pathways and NF-κB translocation, and expression of MHC class II was increased. Mφ from RAGE–/– mice produced significantly lower amounts of TNF, IL-1β and IL-6, while IL-1RI–/– and TLR2–/– Mφ produced cytokine levels comparable with wildtype controls in response to HMGB1 stimulation. We conclude that HMGB1 has the potential to induce a proinflammatory phenotype in Mφ, with RAGE as the major activation-inducing receptor.
    Type of Medium: Electronic Resource
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