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  • 2020-2022  (8)
  • 1980-1984  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurocytology 10 (1981), S. 805-818 
    ISSN: 1573-7381
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A quantitative light microscopic analysis of the ventral grey matter in the lumbar spinal cord of homozygous nude (nu/nu) and heterozygous (nu/+) mice was performed to determine the possible contribution of lymphocytes to normal C.N.S. tissue. If lymphocytes were present in the neuropil, they could be mistaken for neuroglial cells. Athymic nude mice offer a good model, since they lack T-lymphocytes and symptoms of neurological involvement. Mean cell counts from 1 μm sections were tested by analysis of variance. There were no strain differences for the area and number of neurons. The total neuroglial cell count was also similar, but the number of oligodendrocytes decreased 28%, astrocytes increased 51% and microglia were unchanged in the nude compared with the heterozygous mouse. There were no qualitative differences at the ultrastructural level among the neuroglia of either strain. Either the genetic defect retards and alters neuroglial cell development, or some of the small, round dark nuclei belong to lymphocytes, which have earlier migrated into the C.N.S. parenchyma. Lymphocytes could then participate in a cell-mediated immune response with brain macrophages, which are thought to be primarily derived from mononuclear leukocytes.
    Type of Medium: Electronic Resource
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  • 2
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    In:  [Invited talk] In: DMG-University of Haifa Weekly Seminar Series, 02.11.2020, Online .
    Publication Date: 2021-07-07
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 3
    Publication Date: 2021-04-16
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 4
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    In:  [Talk] In: ASOF Meeting 2020, 28.09.- 30.09.2020, Online .
    Publication Date: 2021-07-12
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 5
    Publication Date: 2021-11-19
    Type: Conference or Workshop Item , NonPeerReviewed
    Format: text
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  • 6
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    In:  EPIC3EGU General Assembly 2020, 2020-05-04-2020-05-08Dissolved Neodymium Isotopes Trace Origin and Spatiotemporal Evolution of Modern Arctic Sea Ice
    Publication Date: 2021-07-27
    Description: The lifetime and thickness of Arctic sea ice have markedly decreased in the recent past. This affects Arctic marine ecosystems and the biological pump, given that sea ice acts as platform and transport medium of marine and atmospheric nutrients. At the same time sea ice reduces light penetration to the Arctic Ocean and restricts ocean/atmosphere exchange. In order to understand the ongoing changes and their implications, reconstructions of source regions and drift trajectories of Arctic sea ice are imperative. Automated ice tracking approaches based on satellite-derived sea-ice motion products (e.g. ICETrack) currently perform well in dense ice fields, but provide limited information at the ice edge or in poorly ice-covered areas. Radiogenic neodymium (Nd) isotopes (εNd) have the potential to serve as a chemical tracer of sea-ice provenance and thus may provide information beyond what can be expected from satellite-based assessments. This potential results from pronounced εNd differences between the distinct marine and riverine sources, which feed the surface waters of the different sea-ice formation regions. We present the first dissolved (〈 0.45 µm) Nd isotope and concentration data obtained from optically clean Arctic first- and multi-year sea ice (ice cores) collected from different ice floes across the Fram Strait during the RV POLARSTERN cruise PS85 in 2014. Our data confirm the preservation of the seawater εNdsignatures in sea ice despite low Nd concentrations (on average ~ 6 pmol/kg) resulting from efficient brine rejection. The large range in εNd signatures (~ -10 to -30) mirrors that of surface waters in various parts of the Arctic Ocean, indicating that differences between ice floes but also between various sections in an individual ice core reflect the origin and evolution of the sea ice over time. Most ice cores have εNd signatures of around -10, suggesting that the sea ice was formed in well-mixed waters in the central Arctic Ocean and transported directly to the Fram Strait via the Transpolar Drift. Some ice cores, however, also revealed highly unradiogenic signatures (εNd 〈 ~ -15) in their youngest (bottom) sections, which we attribute to incorporation of meltwater from Greenland into newly grown sea ice layers. Our new approach facilitates the reconstruction of the origin and spatiotemporal evolution of isolated sea-ice floes in the future Arctic.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 7
    Publication Date: 2021-07-21
    Description: The development of the South Asian monsoon (SAM) and Himalaya‐Tibetan Plateau uplift were closely intertwined with some studies suggesting that uplift initiated the monsoon whereas others link tectonics with monsoon‐controlled exhumation. Silicate weathering controls atmospheric CO2 on geological timescales resulting in a large potential for monsoon strength and the Himalayan orogeny to influence global climate but detailed records of SAM‐induced weathering on million year (Myr) timescales are lacking. Here, we present radiogenic Sr, Nd, and Pb isotope compositions of clay minerals produced by silicate weathering and transported to the central Bay of Bengal. The radiogenic isotope data exhibit a relatively small range and demonstrate a remarkably consistent mixture of sources dominated by Himalayan rocks and the Indo‐Burman ranges, which consist of sediments derived from the Himalayas. This suggests that the spatial pattern of regional weathering, which today is highest in the regions of strongest monsoon rains, has persisted in a similar form for the last 27 Myrs. A pronounced increase in primary clay mineral abundance (from 9% to 22%) coincident with global cooling 13.9 Myrs ago points to a shift in the weathering regime given that the clay provenance did not change dramatically. Relatively weaker chemical weathering intensity during the mid and late Miocene cooling suggests increased aridity and changes in the large scale atmospheric circulation in the SAM domain. The establishment of the dry winter monsoon season during the mid and late Miocene may have caused this shift in the weathering regime and can reconcile much of the contrasting evidence for SAM initiation.
    Description: Key Points: Relatively stable mixture of source rocks weathered to clays over the past 27 Myrs Pronounced increase in primary clay minerals occurred 13.9 Myrs ago Shift in weathering regime possibly result of winter monsoon dry season development
    Keywords: 551.3 ; Bay of Bengal ; clay minerals ; radiogenic Sr, Nd, Pb isotopes ; Silicate silicate weathering ; South Asian monsoon
    Type: article
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  • 8
    Publication Date: 2021-07-21
    Description: Tectonics and regional monsoon strength control weathering and erosion regimes of the watersheds feeding into the Bay of Bengal, which are important contributors to global climate evolution via carbon cycle feedbacks. The detailed mechanisms controlling the input of terrigenous clay to the Bay of Bengal on tectonic to orbital timescales are, however, not yet well understood. We produced orbital‐scale resolution geochemical records for International Ocean Discovery Program Site U1443 (southern Bay of Bengal) across five key climatic intervals of the middle to late Miocene (15.8–9.5 Ma). Our new radiogenic Sr, Nd, and Pb isotope time series of clays transported to the Ninetyeast Ridge suggest that the individual contributions from different erosional sources overall remained remarkably consistent during the Miocene despite major tectonic reorganizations in the Himalayas. On orbital timescales, however, high‐resolution data from the five investigated intervals show marked fluctuations of all three isotope systems. Interestingly, the variability was much higher within the Miocene Climatic Optimum (around 16–15 Ma) and across the major global cooling (~13.9–13.8 Ma) until ~13.5 Ma, than during younger time intervals. This change is attributed to a major restriction on the supply of High Himalayan erosion products due to migration of the peak precipitation area toward the frontal domains of the Himalayas and the Indo‐Burman Ranges. The transient excursions of the radiogenic isotope signals on orbital timescales most likely reflect climatically driven shifts in monsoon strength.
    Description: Key Points: A consistent mix of clay sources contributed to the Bay of Bengal throughout the middle to late Miocene A marked change in detrital Sr, Nd, and Pb isotope variability at 13.5 Ma was related to Miocene global cooling Transient orbital‐scale fluctuations in clay source most likely reflect changes in monsoon intensity
    Description: Deutsche Forschungsgemeinschaft (DFG) http://dx.doi.org/10.13039/501100001659
    Keywords: 551 ; Bay of Bengal ; IODP Site U1443 ; Miocene ; sediment provenance ; Himalayas ; weathering ; erosion
    Type: article
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  • 9
    Publication Date: 2021-10-01
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Format: application/pdf
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