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  • 1
    Keywords: Medical Microbiology ; Medical microbiology ; Microbiology ; Biomedical engineering ; Gastroenterology  ; Bacterial Infections prevention & control ; Biofilms
    Description / Table of Contents: Chapter 1 - An Introduction to Microbial Biofilm -- Chapter 2 - Biofilms: The Good and the Bad -- Chapter 3 - Biofilms in Human Health -- Chapter 4 - The Role of Biofilms in Originating, Mediating, and Proliferating Infectious Diseases -- Chapter 5 - Modern Methods in Microscopy for the Assessment of Biofilms -- Chapter 6 - Molecular Methods for the Assessment of Microbial Biofilms -- Chapter 7 - Biofilm Mediated Dental Diseases -- Chapter 8 - Biofilm Mediated Diseases of the Eye -- Chapter 9 - Biofilm mediated Diseases of the Ear, Nose, and Throat -- Chapter 10 - Biofilm mediated Diseases of Heart and Lungs -- Chapter 11 - Role of Biofilms in Medical Devices and Implants -- Chapter 12 - Biofilm Mediated Gastrointestinal Diseases -- Chapter 13 - Biofilm Mediated Urinary Tract Infections -- Chapter 14 - Biofilm Mediated Skin Infections -- Chapter 15 - Approaches Towards Microbial Biofilm Disruption by Natural Bioactive Agents -- Chapter 16 - Probiotics and Biofilm -- Chapter 17 - Probiotics to Counteract Biofilm-Associated Infections -- Chapter 18 - Biofilms and Antimicrobial Resistance -- Chapter 19 - Management of Inflammatory Bowel Disease by Probiotics Biofilm
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XVII, 311 p. 49 illus., 43 illus. in color)
    Edition: 1st ed. 2019
    ISBN: 9783030307578
    Series Statement: Springer eBooks
    Language: English
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  • 2
    Online Resource
    Online Resource
    Newark :John Wiley & Sons, Incorporated,
    Keywords: Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (360 pages)
    Edition: 1st ed.
    ISBN: 9781119891529
    Language: English
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  • 3
    Online Resource
    Online Resource
    Singapore :Springer Singapore Pte. Limited,
    Keywords: Plants-Effect of stress on-Congresses. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (507 pages)
    Edition: 1st ed.
    ISBN: 9789811506901
    Series Statement: Energy, Environment, and Sustainability Series
    Language: English
    Note: Intro -- Preface -- Contents -- Editors and Contributors -- 1 Molecular Approaches in Plant Biology and Environmental Challenges -- References -- 2 Promising Transcription Factors for Salt and Drought Tolerance in Plants -- 2.1 Introduction -- 2.2 Plant Growth During Drought and/or Salinity Stress -- 2.3 Plant Response Towards Stress -- 2.3.1 Stress Perception and Signal Transduction -- 2.3.2 Physiological, Biochemical and Molecular Responses to Drought and Salinity Stress -- 2.4 Transcription Factors: Potential Candidates for Enhancing Multiple Stress Tolerance -- 2.4.1 Transcriptional Regulatory Network Under Drought and Salinity Stress -- 2.4.2 Downstream Targets of Stress-Responsive Transcription Factors -- 2.4.3 Major Transcription Factor Families that Participate in Drought and Salinity Tolerance -- 2.5 Stress-Inducible Promoters: A Potential Tool to Develop Plants with Sustainable Stress Tolerance -- 2.6 Conclusions -- References -- 3 Role of Superoxide Dismutases (SODs) in Stress Tolerance in Plants -- 3.1 Introduction -- 3.2 Different Classes of SODs -- 3.2.1 Cu-ZnSODs -- 3.2.2 FeSODs -- 3.2.3 MnSODs -- 3.3 Evolution of SOD Isoforms -- 3.4 Role of SODs Under Abiotic Stress Conditions -- 3.4.1 Heat Stress -- 3.4.2 Drought Stress -- 3.4.3 Cold Stress -- 3.4.4 Salinity Stress -- 3.4.5 Heavy Metal Stress -- 3.5 Biotic Stress -- 3.6 Industrial Uses of SODs -- 3.6.1 Agriculture and Horticulture Uses -- 3.6.2 Human Health Benefits -- 3.6.3 Uses in Cosmetics -- 3.7 Conclusions -- References -- 4 Receptor-Like Kinases and Environmental Stress in Plants -- 4.1 Introduction -- 4.2 Origin of RLKs -- 4.3 Types of RLKs -- 4.4 Evolutionary Study of RLKs in Plant Lineages -- 4.5 Role of RLKs in Signal Transduction Pathways -- 4.5.1 Brassinosteroid Complexes Mediated Signaling -- 4.5.2 CLAVATA Complexes Mediated Signaling. , 4.6 Role of RLKs in Biotic Stress -- 4.7 Role of RLKs in Abiotic Stress -- 4.7.1 RLKs Against Drought Stress -- 4.7.2 RLKs Against Heat Stress -- 4.7.3 RLKs Against Salt Stress -- 4.7.4 RLKs Against Cold Stress -- 4.7.5 RLKs Against Metal Stress -- 4.7.6 RLKs Against Other Abiotic Stresses -- 4.8 Conclusion -- References -- 5 Role of Histone Acetyltransferases in Plant Abiotic Stress -- 5.1 Introduction -- 5.1.1 Types of HATs -- 5.2 Abiotic Stress and Epigenetics -- 5.2.1 Cold Stress -- 5.2.2 Heat Stress -- 5.2.3 Water Stress -- 5.2.4 Salt Stress -- 5.2.5 Nutritional Stress -- 5.2.6 Light Stress -- 5.3 Conclusion -- References -- 6 Function of Plant Heat Shock Transcription Factors in Abiotic Stress -- 6.1 Introduction -- 6.2 Structure of Plant Heat Shock Transcription Factors -- 6.3 Hsfs in Abiotic Stress Response -- 6.3.1 Heat Stress -- 6.3.2 Salt Stress -- 6.3.3 Drought Stress -- 6.3.4 Heavy Metal Stress -- 6.3.5 Cold/Chilling Stress -- 6.3.6 Anoxia Stress -- 6.4 Conclusion -- References -- 7 Mode of Communication Between Plants During Environmental Stress -- 7.1 Introduction -- 7.2 The Need of Communication in Plant -- 7.3 Different Mode of Communication -- 7.3.1 Communication via Mediator -- 7.3.2 Communication Without Mediator -- 7.4 Molecular Mechanism Underlying Plant Communications -- 7.5 Conclusion and Future Prospects -- References -- 8 Molecular Approaches for Combating Multiple Abiotic Stresses in Crops of Arid and Semi-arid Region -- 8.1 Introduction -- 8.2 Effect of Various Abiotic Stresses on Crop Plants -- 8.2.1 Drought -- 8.2.2 Salt Stress -- 8.2.3 High Temperature Stress -- 8.3 Common Effector Molecules and Signal Transduction Mechanism Under Multiple Abiotic Stresses -- 8.3.1 Plants Response to Individual and Interactive Abiotic Stress Condition -- 8.3.2 Physio-Biochemical Response of Plants to Various Abiotic Stress. , 8.3.3 Molecular Response of Plants to Various Abiotic Stresses -- 8.3.4 Plant Signal Transduction Mechanism Under the Influence of Abiotic Stresses -- 8.3.5 Gene Expression Regulation and Transcription Factors -- 8.4 Combating Abiotic Stresses Using Physiological and Biochemical Approaches -- 8.4.1 Role of Proline and Glycine Betaine -- 8.4.2 Role of Plant Antioxidants in Improving Plant Tolerance to Stress -- 8.4.3 Role of Mineral Nutrition and Management of Nutrient Supply -- 8.4.4 Role of Plant Growth Hormones -- 8.5 Combating Abiotic Stresses Using Molecular Approaches -- 8.5.1 Sequencing Based Approaches -- 8.5.2 Hybridization Based Approaches -- 8.5.3 Gene Inactivation-Based Approaches -- 8.5.4 Genome Editing Based Approaches -- 8.6 Conclusion -- References -- 9 Applications of Landscape Genetics to Study the Effect of Varying Landscapes and Environmental Challenges in Plant Populations -- 9.1 Introduction -- 9.1.1 Definition -- 9.2 Landscape Ecology: The Basics -- 9.2.1 Landscape -- 9.2.2 Effect of Landscapes on Genetic Processes -- 9.2.3 Population Dynamics and Dispersal -- 9.2.4 Influence of Landscapes on Genetic Variation -- 9.2.5 Gene Flow -- 9.3 Overview of Dna Types and Molecular Methods -- 9.3.1 Types of DNA -- 9.3.2 Molecular Methods -- 9.3.3 Measures of Genetic Diversity -- 9.3.4 Bayesian Clustering Methods -- 9.3.5 Barrier Detection Methods -- 9.4 Genomic Approaches in Landscape Genetics -- 9.5 Effect of Climate Change and Spatial Data Collection -- 9.6 Conclusion and Future Perspectives -- References -- 10 Arsenic in Rice Grain: Role of Transporters in Arsenic Accumulation -- 10.1 Introduction -- 10.2 Arsenic in Soil -- 10.3 Arsenic Toxicity -- 10.3.1 Human -- 10.3.2 Plant -- 10.4 Arsenic in Rice Grain -- 10.5 Arsenic Transport in Plant -- 10.5.1 Arsenite Transport -- 10.5.2 Arsenate Acquisition -- 10.5.3 Organo-Arsenic Transport. , 10.6 Arsenic Metabolism in Plant -- 10.7 Root to Shoot Translocation of as in Plant -- 10.8 Role of Transporters in Arsenic Uptake and Movement -- 10.8.1 Lsi -- 10.8.2 ABCC -- 10.8.3 NRAMP -- 10.8.4 MATE -- 10.9 Conclusions -- References -- 11 Metabolic Engineering of Stress Protectant Secondary Metabolites to Confer Abiotic Stress Tolerance in Plants -- 11.1 Introduction -- 11.2 Abiotic Stress Protectant Secondary Metabolites -- 11.2.1 Isoprenoids -- 11.2.2 Phenolics and Flavonoids -- 11.2.3 Carotenoids -- 11.3 Changes in Metabolic Pathways During Abiotic Stress -- 11.4 Metabolic Engineering of Secondary Metabolites -- 11.4.1 Manipulation of Isoprenoids -- 11.4.2 Manipulation of Flavonoids -- 11.4.3 Manipulation of Carotenoids -- 11.5 Conclusion -- References -- 12 An Update on Molecular Strategies of Transgenic Rice Tolerance to Abiotic Stresses -- 12.1 Introduction -- 12.2 Development of Transgenic Rice Tolerant to Various Abiotic Stresses -- 12.2.1 Development of Transgenic Rice for Salt Tolerance -- 12.2.2 Development of Transgenic Rice Tolerant to Drought Stress -- 12.2.3 Transgenic Rice Developed for Tolerance to Cold Stress -- 12.2.4 Transgenic Rice Developed for Tolerance to Heat Stress -- 12.3 Pleiotropic Effects of Transgenes for Multiple Stress Tolerance -- 12.4 Conclusion -- References -- 13 An Update on the Applications of CRISPR/Cas9 Technology in Tomato -- 13.1 Introduction -- 13.1.1 An Array of Cas9 Activities -- 13.2 Uses of CRISPR/Cas9 in Crop Improvement -- 13.2.1 Experimental -- 13.2.2 Applications -- 13.3 Conclusion -- References -- 14 Transgenic Approaches for Enhancement of Salinity Stress Tolerance in Plants -- 14.1 Introduction -- 14.2 Mechanisms of Salt Stress Response in Plants -- 14.2.1 Biphasic Response -- 14.2.2 Strategies to Combat Salt Stress in Plants. , 14.3 Genetic Engineering Approaches to Improve Salinity Stress Tolerance in Plants -- 14.3.1 Genes Involved in Direct Protection (Functional Proteins/Stress-Adaptive Compounds) -- 14.3.2 Genes for Regulatory Proteins and Signaling Intermediates -- 14.3.3 Genes for Ion Homeostasis -- 14.4 Conclusions and Future Perspective -- References -- 15 Genome Engineering in Rice: Applications, Advancements and Future Perspectives -- 15.1 Introduction -- 15.2 Gene Editing Tools: ZFN, TALEN & -- CRISPR-Cas System -- 15.3 Applications of Genome Editing in Rice Crop Improvement -- 15.4 Innovations in Genome Editing -- 15.5 The Need for Genome Editing and Its Social Acceptance -- 15.6 Conclusion and Future Perspective -- References -- 16 Secondary Metabolite Pathways in Medicinal Plants: Approaches in Reconstruction and Analysis -- 16.1 Introduction -- 16.2 Secondary Metabolites: Concept and Classification -- 16.2.1 Phenylpropanoids -- 16.2.2 Alkaloids -- 16.2.3 Terpenoids -- 16.3 Biosynthesis of Secondary Metabolite Is Under Tight Regulation -- 16.3.1 Abiotic and Biotic Effects -- 16.3.2 Other Regulatory Aspects -- 16.4 Gene Mining and Pathway Elucidation -- 16.4.1 Transcriptomics -- 16.4.2 Proteomics -- 16.4.3 Metabolomics -- 16.4.4 Bioinformatics Approaches -- 16.4.5 Systems Biology -- 16.5 Approaches for Functional Genomics -- 16.5.1 RNAi -- 16.5.2 VIGS -- 16.5.3 CRISPR-Cas9 System -- 16.6 Tools for Enhancement of Secondary Metabolites -- 16.6.1 Bioprocessing -- 16.6.2 Heterologous Production -- 16.6.3 Particle Bombardment Mediated Transformation -- 16.7 Conclusion -- References -- 17 Molecular Biology of Glandular Trichomes and Their Functions in Environmental Stresses -- 17.1 Introduction -- 17.2 Morphology and Classification of Glandular Trichomes -- 17.3 Glandular Trichomes as Source of Economically Important Natural Products. , 17.4 Role of Glandular Trichomes in Plant Biology.
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  • 4
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Ring formation (Chemistry). ; Electronic books.
    Description / Table of Contents: Pericyclic Reactions: A Mechanistic and Problem-Solving Approach provides complete and systematic coverage of pericyclic reactions for researchers and graduate students in organic chemistry and pharmacy programs. Drawing from their cumulative years of teaching in the area, the authors use a clear, problem-solving approach, supplemented with colorful figures and illustrative examples. Written in an accessible and engaging manner, this book covers electrocyclic reactions, sigmatropic reactions, cycloaddition reactions, 1,3-dipolar reactions, group transfer, and ene reactions. It offers an in-depth study of the basic principles of these topics, and devotes equal time to problems and their solutions to further explore those principles and aid reader understanding. Additional practice problems are provided for further study and course use. Comprehensive coverage of important topics such as 1,3 dipolar, pyrolytic, and cycloaddition reactions Problem-solving approach with clear figures and many worked and unworked problems Contents are applicable to advanced students and researchers in organic chemistry.
    Type of Medium: Online Resource
    Pages: 1 online resource (383 pages)
    Edition: 1st ed.
    ISBN: 9780128036693
    DDC: 547/.2
    Language: English
    Note: Front Cover -- Pericyclic Reactions -- Copyright -- To Our Families -- Contents -- Preface -- Chapter 1 - Pericyclic Reactions and Molecular Orbital Symmetry -- 1.1 CLASSIFICATION OF PERICYCLIC REACTIONS -- 1.2 MOLECULAR ORBITALS OF ALKENES AND CONJUGATED POLYENE SYSTEMS -- 1.3 MOLECULAR ORBITALS OF CONJUGATED IONS OR RADICALS -- 1.4 SYMMETRY PROPERTIES OF π OR σ-MOLECULAR ORBITALS -- 1.5 ANALYSIS OF PERICYCLIC REACTIONS -- FURTHER READING -- Chapter 2 - Electrocyclic Reactions -- 2.1 CONROTATORY AND DISROTATORY MODES -- 2.2 STEREOCHEMISTRY OF ELECTROCYCLIC REACTIONS -- 2.3 SELECTION RULES FOR ELECTROCYCLIC REACTIONS -- 2.4 ANALYSIS OF ELECTROCYCLIC REACTIONS -- 2.5 ELECTROCYCLIC REACTIONS OF IONIC SPECIES -- Chapter 3 - Sigmatropic Rearrangements -- 3.1 SUPRAFACIAL AND ANTARAFACIAL PROCESSES -- 3.2 ANALYSIS OF SIGMATROPIC REARRANGEMENTS OF HYDROGEN -- 3.3 ANALYSIS OF SIGMATROPIC REARRANGEMENTS OF ALKYL GROUP -- 3.4 [3,3] SIGMATROPIC REARRANGEMENTS -- 3.5 [5,5] SIGMATROPIC SHIFT -- 3.6 [2,3] SIGMATROPIC REARRANGEMENTS -- 3.7 PERIPATETIC CYCLOPROPANE BRIDGE: WALK REARRANGEMENTS -- 3.8 SIGMATROPIC REARRANGEMENTS INVOLVING IONIC TRANSITION STATES -- Chapter 4 - Cycloaddition Reactions -- 4.1 STEREOCHEMICAL MODES OF CYCLOADDITION -- 4.2 FEASIBILITY OF CYCLOADDITION REACTIONS -- 4.3 [2+2] CYCLOADDITIONS -- 4.4 [4+2] CYCLOADDITIONS -- 4.5 HIGHER CYCLOADDITIONS -- 4.6 CYCLOADDITION OF MULTIPLE COMPONENTS -- Chapter 5 - Cheletropic Reactions and 1,3-Dipolar Cycloadditions -- 5.1 CHELETROPIC REACTIONS -- 5.2 1,3-DIPOLAR CYCLOADDITIONS -- Chapter 6 - Group Transfer, Elimination, and Related Reactions -- 6.1 GROUP TRANSFER REACTIONS -- 6.2 ELIMINATION REACTIONS -- 6.3 DYOTROPIC REARRANGEMENTS -- 6.4 ENE REACTIONS -- 6.5 β-ELIMINATIONS INVOLVING CYCLIC TRANSITION STRUCTURES -- Chapter 7 - Unsolved Problems -- Appendix - Solution Manual -- Index.
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing AG,
    Keywords: Biofilms. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (318 pages)
    Edition: 1st ed.
    ISBN: 9783030307578
    Language: English
    Note: Intro -- Foreword -- Preface -- Contents -- Contributors -- Abbreviations -- 1 An Introduction to Microbial Biofilm -- 1.1 Introduction -- 1.1.1 Biofilm Growth and Development -- 1.1.2 Beneficial and Naturally Occurring Biofilms -- 1.1.3 The Harmful Effects of Biofilm Formation -- 1.1.4 Naturally Occurring Biofilms -- 1.1.5 Biofilms in Health and Medicine -- 1.1.6 Control of Biofilms -- 1.1.7 Biofilm and Antibiotic Resistance -- 1.1.8 The Future of Studying Biofilms -- References -- 2 Biofilms: The Good and the Bad -- 2.1 Introduction -- 2.2 Mechanism of Bacterial Biofilm Formation -- 2.2.1 The Conditioning Layer -- 2.2.2 Reversible Adhesion -- 2.2.3 Irreversible Adhesion -- 2.2.4 Micro-colony Formation and Three-Dimensional Growth -- 2.2.5 Biofilm Formation -- 2.2.6 Maturation and Dispersal -- 2.3 Applications of Biofilms -- 2.3.1 Biofilm Uses -- 2.3.2 Bioremediation -- 2.4 Oil Spills and Contaminated Groundwater -- 2.5 Microbial Leaching -- 2.6 Biofilm Reactors -- 2.7 Biofilms in Biosensors -- 2.8 Biofilm Integrated Nanofiber Display -- 2.9 The Harmful Effects of Biofilms -- 2.9.1 The Food and Dairy Industry -- 2.9.2 Aquaculture and the Sea Food Industry -- 2.9.3 The Brewing Industry -- 2.9.4 Bio-corrosion -- 2.9.5 The Medical Industry -- References -- 3 Biofilms in Human Health -- 3.1 Introduction -- 3.2 Biofilm Structure -- 3.3 Biofilm Development -- 3.3.1 Growth of Conditioning Film on Surface -- 3.3.2 Movement of Microorganisms Towards Surface -- 3.3.3 Adherence -- 3.3.4 Colonization for Development and Division of Microbe, Formation of Microcolony and Biofilms, Change in Genotype and Phenotype -- 3.3.5 Interaction of Microorganisms inside Biofilm -- 3.4 Antibiotics and Biofilms -- 3.5 Pathogenic Mechanisms -- 3.6 Biofilm and Human Diseases -- 3.6.1 Oral Cavity -- 3.6.2 Upper Airways -- 3.6.3 Lower Airways. , 3.6.4 Gastrointestinal and Urinary Tracts -- 3.6.5 Wounds -- 3.7 Main Characteristics of Biofilm Mediated Diseases -- References -- 4 The Role of Biofilm in Originating, Mediating, and Proliferating Infectious Diseases -- 4.1 Introduction -- 4.1.1 Biofilm Origination and Mediation -- 4.2 Indwelling Devices Where Microbes Frequently Cause Biofilms -- 4.3 Biofilm-Mediated Infectious Diseases -- 4.3.1 Barrett's Esophagus and Gastric Cancer -- 4.3.2 Endotracheal Tube Colonization and Ventilator-Associated Pneumonia -- 4.3.3 Cystic Fibrosis -- 4.3.4 Chronic Otitis Media -- 4.3.5 Dental Plaque -- 4.3.6 Urinary Tract and Catheter-Associated Infections -- 4.3.7 Skin Infections by Staphylococcus -- 4.3.8 Chronic Ulcers -- 4.3.9 Prosthetic Graft Infection -- 4.3.10 Healthcare-Associated Infections -- 4.4 Other Biofilm-Mediated Infections -- 4.5 Conclusion -- References -- 5 Modern Methods in Microscopy for the Assessment of Biofilms -- 5.1 Introduction -- 5.2 Diagnosis of Biofilm Infections -- 5.2.1 Routine Microbiological Examination -- 5.2.2 Different Microscopic Methods -- 5.3 Conclusion -- References -- 6 Molecular Methods for the Assessment of Microbial Biofilms -- 6.1 Introduction -- 6.2 Why Molecular Methods? -- 6.3 Different Methods Used to Assess Biofilm: Ergin (2017) -- 6.4 Next-Generation Sequencing Technology -- 6.4.1 Advantages of NGS -- 6.4.2 Utility of NGS in Clinical Microbiology: Deurenberg et al. (2016) -- 6.4.3 Workflow of NGS -- 6.4.4 Clinical Sample/Specimen -- 6.4.5 Nucleic Acids Sequencing -- 6.4.6 Sequence Data Analysis -- 6.4.7 Application of NGS -- 6.5 Polymerase Chain Reaction (PCR) -- 6.5.1 Advantage of PCR -- 6.5.2 Workflow of PCR -- 6.5.3 Procedure and General Protocol -- 6.5.4 1-1.8% Agarose Gel Electrophoresis -- 6.5.5 Application of PCR -- 6.6 DNA-DNA Hybridization -- 6.6.1 Principle of DNA-DNA Hybridization. , 6.6.2 Major Disadvantages -- 6.6.3 DDH Protocol and Procedure -- 6.6.4 Application of DNA-DNA Hybridization -- 6.7 Microarray Technology -- 6.7.1 Application of Microarray -- References -- 7 Biofilm-Mediated Dental Diseases -- 7.1 Introduction -- 7.2 Oral Flora -- 7.3 Development -- 7.4 Oral Microbiota: Beneficial Functions -- 7.5 Oral Niches -- 7.5.1 Tongue and Buccal Mucosa -- 7.5.2 Tooth Surface -- 7.5.3 Gingival Crevice and Its Epithelium -- 7.5.4 Dental Appliances and Prosthetics -- 7.6 Factors Modulating Microbial Growth -- 7.6.1 Anatomic Factors -- 7.6.2 Saliva -- 7.6.3 Gingival Crevicular Fluid -- 7.6.4 Microbial Factors -- 7.6.5 Environmental Factors -- 7.6.6 Miscellaneous -- 7.7 Nutrition -- 7.7.1 Host Resources -- 7.7.2 Microbial Resources -- 7.8 Dental Plaque -- 7.9 Dental Plaque and Caries -- 7.9.1 Caries Origin Hypothesis -- 7.10 Dental Plaque, Dental Calculus, and Periodontitis -- 7.10.1 Calculus -- 7.10.2 Classification of Periodontal Disease -- 7.10.3 Etiology of Periodontal Disease -- 7.11 The Systemic Connection of Oral Biofilms -- 7.12 Approaches for Control of Dental Biofilm -- 7.12.1 Conventional Treatment -- 7.12.2 Mechanical Plaque Control -- 7.12.3 Oral Irrigators (Mandal et al. 2017) -- 7.12.4 Chemical Plaque Control -- 7.12.5 Local Delivery of Drugs -- References -- 8 Biofilm-Mediated Diseases of the Eye -- 8.1 Introduction -- 8.2 Endophthalmitis -- 8.3 Contact Lens Associated Keratitis -- 8.4 Crystalline Keratopathy -- 8.5 Dry Eye -- 8.6 Ocular Implants and Biofilms -- 8.6.1 Conjunctival Plug -- 8.6.2 Scleral Buckles -- 8.6.3 Lacrimal Intubation Devices -- 8.6.4 Orbital Implants -- 8.6.5 Other Biomaterials Used in Ophthalmology -- 8.7 Prevention and Treatment of Biofilms -- References -- 9 Biofilm-Mediated Diseases of the Ear, Nose, and Throat (ENT) -- 9.1 Introduction -- 9.2 Chronic Rhino-sinusitis. , 9.3 Otitis Media with Effusion -- 9.4 Cholesteatoma -- 9.5 Adenotonsillitis -- 9.6 Biofilms in Ear, Nose, and Throat Implants and Prostheses -- 9.7 Treatment -- 9.8 Prevention -- 9.9 Conclusion -- References -- 10 Biofilm-Mediated Diseases of the Heart and Lungs -- 10.1 Introduction -- 10.2 Biofilms Related to Endotracheal Tubes and Ventilator-Associated Pneumonia -- 10.3 Biofilms in Cystic Fibrosis -- 10.4 Biofilms in Pulmonary Infections -- 10.5 Biofilms in Indwelling Vascular Catheters -- 10.6 Mechanical Heart Valve Biofilms -- 10.7 Biofilms in Infective Endocarditis -- 10.8 Biofilms in Atherosclerosis -- 10.9 Cardiovascular Implantable Electronic Devices -- 10.10 Conclusion -- References -- 11 The Role of Biofilms in Medical Devices and Implants -- 11.1 Introduction -- 11.2 Mechanism of Biofilm Formation -- 11.3 Prevention and Control of Biofilms -- 11.3.1 Cell Repellent and Non-adhesive Coatings -- 11.3.2 The Active Release of Antimicrobial Compounds and Biofilm Inhibitors -- 11.3.3 Antimicrobial Coatings with Tethered Biocides -- 11.3.4 Competitive Adherence by Benign Organisms -- 11.4 Biofilms and Healthcare-Associated Infections -- 11.4.1 Central Venous Catheters -- 11.4.2 Urinary Catheters -- 11.4.3 Ventilator-Associated Pneumonia and Endotracheal Tubes -- 11.4.4 Surgical Site Infection -- 11.4.5 Mechanical Heart Valves -- 11.4.6 Contact Lenses -- 11.4.7 Orthopedic Implants -- 11.4.8 Dental Implants -- 11.4.9 Breast Implants -- 11.5 Detection and Diagnosis of Bacterial Biofilms on Medical Devices -- 11.6 Preventive Measures for Biofilm Control and Future Perspectives -- 11.7 Conclusion -- References -- 12 Biofilm-mediated Gastrointestinal Diseases -- 12.1 Introduction -- 12.2 Esophagus -- 12.2.1 Gastroesophageal Reflux Disease and Barret's Esophagus -- 12.2.2 Carcinoma of the Esophagus -- 12.3 Stomach -- 12.3.1 Helicobacter pylori Infection. , 12.4 Intestines -- 12.4.1 Foodborne Bacterial Disease and Biofilm -- 12.4.2 Clostridium Difficile -- 12.4.3 Inflammatory Bowel Disease -- 12.4.4 Irritable Bowel Syndrome -- 12.4.5 Colorectal Malignancy -- References -- 13 Biofilm-Mediated Urinary Tract Infections -- 13.1 Infections in Urinary Tract -- 13.2 Pathogenesis of Biofilm-Mediated UTIs -- 13.2.1 Role of Biofilms in Recurrent UTIs -- 13.2.2 Role of Biofilm in ABU -- 13.2.3 Role of Biofilms in Catheter-Associated Infections -- 13.3 Microbial Factors Contributing to Biofilm Formation in Urinary Tract -- 13.3.1 Escherichia coli and Urinary Tract Infections -- 13.3.2 Proteus mirabilis and Urinary Tract Infections -- 13.3.3 Klebsiella pneumoniae and Urinary Tract Infections -- 13.3.4 Pseudomonas aeruginosa and Urinary Tract Infections -- 13.3.5 Miscellaneous Microorganisms and Urinary Tract Infections -- 13.4 Treatment and Prevention of Biofilm-Mediated UTIs -- 13.4.1 Antimicrobial Treatment of Biofilms -- 13.4.2 Newer Strategies -- 13.5 Future Prospects -- 13.5.1 Bladder Model -- 13.5.2 Urinary Tract Model -- 13.5.3 CAUTI Model -- 13.5.4 Meatus Model -- References -- 14 Biofilm-Mediated Skin Infections -- 14.1 Introduction -- 14.2 Role of Biofilm in Skin Infection -- 14.3 Biofilm Formation and Cell-to-Cell Communication -- 14.4 Pathogenesis and Types of Skin Infection Caused by Biofilms -- 14.4.1 Rosacea -- 14.4.2 Acne Vulgaris -- 14.4.3 Atopic Dermatitis -- 14.4.4 Cellulitis, Erythema Nosodum, and Erysipelas -- 14.4.5 Onychomycosis -- 14.4.6 Furuncles and Impetigo -- 14.4.7 Staphylococcal Scalded Skin Syndrome -- 14.4.8 Miliaria -- 14.4.9 Necrotizing Fasciitis -- 14.4.10 Pseudomonas Infections of the Skin -- 14.4.11 Paronychia -- 14.4.12 Chronic Non-healing Ulcers -- 14.4.13 Other Biofilm-Related Skin Infections -- 14.5 Conclusion -- References. , 15 Approaches Towards Microbial Biofilm Disruption by Natural Bioactive Agents.
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  • 6
    Online Resource
    Online Resource
    Milton :Taylor & Francis Group,
    Keywords: Phyllanthus. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (105 pages)
    Edition: 1st ed.
    ISBN: 9781000064742
    Series Statement: Phytochemical Investigations of Medicinal Plants Series
    DDC: 583.69
    Language: English
    Note: Cover -- Half Title -- Series Page -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Acknowledgments -- Authors -- List of Abbreviations and Units -- 1 Introduction: Phyllanthus-Ethno- and Phytopharmacological Review -- 1.1 Introduction -- 1.2 Traditional Uses and Medicinal Properties of Phyllanthus -- 1.3 Phytochemistry -- 1.4 Pharmacological Activity -- 1.5 Phytochemical Analysis -- 2 Screening of Phytochemicals in P. Amarus by HPLC-ESI-QTOF-MS/MS -- 2.1 Methods Used for Analysis -- 2.2 Plant Collection and Extraction -- 2.3 LC-MS Analysis of Phytochemicals -- 2.4 Qualitative Analysis -- 2.4.1 Hydroxybenzoic and Hydroxycinnamic Acid Derivatives -- 2.4.2 Flavonoids -- 2.4.3 Ellagic Acid and their Derivatives -- 2.4.4 Lignans -- 2.4.5 Other Compounds -- 2.5 Quantitative Analysis -- 2.6 Distribution of Bioactive Compounds -- 2.7 PCA of HPLC-ESI-QTOF-MS Fingerprints -- 3 Quantitative Analysis of Bioactive Compounds in Phyllanthus Species and its Herbal Formulations -- 3.1 Rationale for the Investigation -- 3.2 Sample Collection and Extraction -- 3.3 LC-MS Analysis -- 3.4 Quantitative Analysis of Bioactive Compounds -- 3.5 Quantification of  the 23 Components -- 3.6 Differentiation of Plants and Plant Parts -- 4 DART-TOF-MS Analysis of P. Amarus and Study of Geographical Variations -- 4.1 Direct Analysis in Real-Time Mass Spectrometry (DART-MS) -- 4.2 DART-MS Analysis -- 4.3 Chemical Fingerprints -- 4.4 Principal Component Analysis: Discrimination -- 4.5 Conclusion -- References -- Index.
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing AG,
    Keywords: Plant physiology. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (248 pages)
    Edition: 1st ed.
    ISBN: 9783319171579
    DDC: 572.8633
    Language: English
    Note: Intro -- Preface -- Contents -- Contributors -- Chapter 1: Expression Analysis and Genome Annotations with RNA Sequencing -- Introduction -- Sequencing Strategy -- Genome Sequencing -- mRNA Sequencing -- Read Mapping on Reference Sequences -- Pre-processing -- Read Mapping -- SNP Detecting from Genome Sequencing -- Digital Gene Expression Profiling by mRNA-Seq -- Mapping -- Assembly -- Expression Level Estimation and Correction -- Statistical Methods for Gene Expression Data -- Hierarchical Clustering -- Multivariate Analysis Methods -- Principal Component Analysis (PCA) and Correspondence Analysis (CA) -- Self-Organizing Maps and k-Means Clustering -- References -- Chapter 2: The Application of Next Generation Sequencing Techniques to Plant Epigenomics -- Introduction -- Major Findings in Plants -- Development of Genome-Wide Approaches -- Bisulfite-Seq Experiments -- Methods -- General Considerations -- Techniques for Assaying DNA Methylation in Plants Using NGS -- DNA Methylation -- ChIP-Seq -- Nucleosome Positioning -- Small RNA-Seq -- PART3: Analysis of Next Generation Sequencing Data for Epigenomics -- Computing Requirements for Data Analysis -- Quality Control -- Pre-alignment Filtering -- Alignment -- BS-Seq Alignment -- Methylation Calling -- Estimation of Conversion Efficiency -- Downstream Analysis -- Differential Methylation Analysis -- ChIP-Seq Analysis -- Web Services -- Post-Processing -- Peak Calling -- Higher-Level Analysis -- Nucleosome Positioning Analysis -- Small RNA-Seq Analyses -- Data Visualization -- References -- Chapter 3: Whole Genome Sequencing to Identify Genes and QTL in Rice -- Overview of Genetic Analysis for Identifying Genes -- Genetic Markers to Become Obsolete? -- Rice Genetic Resources at IBRC -- MutMap -- MutMap+ -- MutMap-Gap -- QTL-Seq -- SNP-Index -- Summary -- References. , Chapter 4: Variant Calling Using NGS Data in European Aspen (Populus tremula) -- Introduction -- Raw Reads Pre-processing (Step I) -- The Short-Read Alignment (Step II) -- Alignment Algorithms -- Mismatches Between Sample and Reference Genome -- Multiple Mapping -- Post-processing Alignment (Step III) -- Local Realignment Around Indels -- Mark Duplicates -- Base Quality Score Recalibration -- Variant and Genotype Calling (Step IV) -- Methods for Genotype Calling -- Software Tools for Variant Discovery and Genotyping -- SAMtools mpileup and BCFtools -- GATK UnifiedGenotyper -- SNVer -- GATK HaplotypeCaller -- Variant Filtration (Step V) -- Conclusion -- References -- Chapter 5: Leafy Spurge Genomics: A Model Perennial Weed to Investigate Development, Stress Responses, and Invasiveness -- Introduction -- Initial Forays into the Molecular Biology of Leafy Spurge -- Leafy Spurge Enters the Genomic Era -- Experimenting with Transcriptomics -- Outcomes Obtained Using the 23,000 Element Leafy Spurge/Cassava Microarrays -- BAC Library Construction: An Important Tool for Promoter Analysis and the First Step in Full Genome Sequencing -- Shotgun Sequencing of the Leafy Spurge Genome -- Mining Old Data and New -- References -- Chapter 6: Utilization of NGS and Proteomic-Based Approaches to Gain Insights on Cellular Responses to Singlet Oxygen and Improve Energy Yields for Bacterial Stress Adaptation -- Introduction -- Reactive Oxygen Species and Singlet Oxygen -- Sources of 1O2 -- 1O2 Production in Photosynthetic Organisms -- Energy Generation in R. sphaeroides -- Quenching of 1O2 by Carotenoids -- Transcriptional Response to 1O2 by R. sphaeroides -- Alternative Responses to 1O2 by Other Organisms -- Utilization of Next-Generation Sequencing (NGS) Technologies, Proteomic, and Metabolomic Approaches to Characterize Cellular Responses. , Investigations into the Cellular Response to 1O2 and Identification of the σE Regulon -- Coupling Insights to Improved Energy Generation -- References -- Chapter 7: Experimental Evolution and Next Generation Sequencing Illuminate the Evolutionary Trajectories of Microbes -- Introduction -- What Makes Microbes Attractive to Test Evolutionary Processes? -- Experimental Evolution and Mutation Accumulation Dynamics -- The Evolutionary Trajectories of Adaptive Mutations -- Convergent Evolution in Bacterial Experimental Populations -- Experimental Evolution Under Inefficient Natural Selection -- Concluding Remarks -- References -- Chapter 8: Plant Carbohydrate Active Enzyme (CAZyme) Repertoires: A Comparative Study -- Why Do We Study Plant Cell Walls? -- How CAZymes Are Related to Cell Wall Studies? -- What Are CAZymes and the CAZyDB? -- Existing Studies on Plant CAZyomes -- dbCAN: A HMM Database for Large-Scale Analysis of CAZymes -- CAZyome of Fully Sequenced Plants -- Phylogenetic Analysis Is Useful to the Study of the Function and Evolution of CAZymes -- Future Development -- References -- Chapter 9: Metagenomics of Plant-Microbe Interactions -- References -- Chapter 10: Genes and Trans-Factors Underlying Embryogenic Transition in Plant Soma-Cells -- In Vitro Regeneration of Plant Species -- Somatic Embryogenesis -- Initiation of Somatic Embryogenesis -- Somatic Embryogenesis Is Genotype/Explant Source Dependent -- Stress-Mediated Up-regulation of Phytohormone in SE -- Auxin -- Cytokinin -- Abscisic Acid (ABA) -- Gibberellins -- Ethylene -- Induced Cell-Fate For SE -- Cellular Morphology, Physiology and Histological Pattern -- Changes in Gene Expression -- Somatic Embryo Receptor Kinase (SERK) -- WUSCHEL (WUS) -- Baby Boom (BBM) Gene -- WRKY, AOX and Ca2+ -- Altered Cellular Homeostasis Is Essential for Soma Cell-to-­Embryo Transition. , Genomics of Somatic Embryogenesis -- References -- Chapter 11: Bioinformatics Tools to Analyze Proteome and Genome Data -- Introduction -- Bioinformatics Tool to Analyze Proteomics Data -- Bioinformatics Tool to Analyze Genomics Data -- Genomic Repositories -- Similarity Search and Sequence Alignment Tools -- Variation Related Databases -- Gene Prediction Tools -- Expression Profiling Tools -- Tools for Promoter Prediction -- Genome Annotation Tools -- References -- Chapter 12: High-Throughput Transcriptome Analysis of Plant Stress Responses -- Plant Stresses and Its Genetic Regulation -- Transcriptome Analysis Upon Stress Conditions -- Transcriptome De Novo Assembly -- Functional Annotation of Unigenes by BLASTx Against Protein Databases -- Functional Classification of Unigenes by Clusters of Orthologous Groups (COG), Gene Ontology (GO), and KEGG Pathway Enrichment -- Protein Coding Region Prediction (CDS) -- Digital Gene Expression Profiling -- Unigene Expression Difference Analysis -- References -- Chapter 13: CNV and Structural Variation in Plants: Prospects of NGS Approaches -- Copy Number Variation Is Part of Genome Structural Variation -- Diffusion of CNVs Within Genomes -- Mechanisms Leading to Variation in Number of Copies -- Do CNVs Have a Biological Meaning? -- Association to Phenotypes -- Evolutionary and Adaptive Value of CNVs -- NGS Approaches and Bioinformatic Tools for CNV Detection -- The Computational Problem -- NGS and the Main Techniques of CNV Discovery -- A Classification of NGS Technologies -- NGS Technologies vs. Computational Techniques -- Future Perspectives -- References -- Index.
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  • 8
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Metabolites. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (270 pages)
    Edition: 1st ed.
    ISBN: 9780443161599
    Series Statement: Developments in Applied Microbiology and Biotechnology Series
    DDC: 615.7
    Language: English
    Note: Front Cover -- Secondary Metabolites and Biotherapeutics -- Secondary Metabolites and Biotherapeutics -- Copyright -- Contents -- Contributors -- About the authors -- 1 - Introduction to plant secondary metabolites -- 1. Introduction -- 1.1 Alkaloids -- 1.2 Terpenes -- 1.3 Flavonoids -- 1.4 Saponins -- 1.5 Tannins -- 1.6 Phytosterols -- 1.7 Quinones -- 2. Conclusion -- References -- 2 - Identification and purification of plant secondary metabolite as medicinal raw materials -- 1. Introduction -- 2. Several classes of SM found in plants -- 3. Alkaloids -- 4. Compounds containing phenol -- 5. Terpenes -- 6. Techniques employed in the processes of extracting, isolating, and purifying bioactive compounds -- 6.1 Extraction with the assistance of ultrasound -- 6.2 Extraction with the help of microwave-assisted extraction -- 7. Use of different solvents in extracting the phenolic compounds -- 8. Extraction and purification methods for active molecules -- 9. Clarification of the structural components of the bioactive molecules -- 10. Infrared rays spectroscopy -- 11. UV-visible spectroscopy -- 12. The use of mass spectrometry in the identification of chemical compounds -- 13. NMR spectroscopy -- 14. Antioxidant components from plants -- 15. Antimicrobial properties of compound derived from plants -- 16. Examination of phytochemicals -- 17. Secondary metabolites' contributions to pharmacological activity -- 18. Conclusion -- References -- 3 - Biochemical characterization of plant secondary metabolites -- 1. Introduction -- 2. Secondary metabolites -- 3. Therapeutic uses of secondary metabolites -- 3.1 Cardiovascular disorders -- 3.2 Cancer -- 3.3 Parasitic diseases -- 3.4 Neurodegenerative disorders -- 3.5 Diabetes mellitus -- 4. Synthesis of plant secondary metabolites -- 5. Isolation and purification of secondary metabolites. , 5.1 Thin-layer chromatography -- 5.2 High-performance thin layer liquid chromatography -- 5.3 High-performance liquid chromatography -- 5.4 Gas chromatography -- 5.5 Column chromatography -- 5.6 Gel permeation chromatography -- 5.7 Affinity chromatography -- 6. Qualitative assessment of plant extract or secondary metabolites -- 7. Spectroscopy techniques for structural characterization of SMs -- 7.1 UV-visible spectroscopy -- 7.2 Infrared spectroscopy -- 7.3 Fluorescence -- 7.4 Mass spectroscopy -- 7.5 Nuclear magnetic resonance -- 7.6 X-ray diffraction -- 8. Miscellaneous methods -- 8.1 Immunoassay -- 9. Dilemma-primary metabolite or secondary metabolite? -- 10. Dereplication databases -- 11. Pharmacodynamic and pharmacokinetic characterization of SMs -- 11.1 In vitro studies -- 11.2 In vivo studies -- 11.3 In situ model -- 11.4 In silico studies -- 12. Toxicological characterization of SMs -- 13. Conclusion -- References -- 4 - Production of secondary metabolites from medicinal plants through tissue culture -- 1. Introduction -- 2. Medicinal plant -- 3. Secondary metabolite -- 4. Types of secondary metabolites -- 4.1 Phenolics -- 4.2 Alkaloid -- 4.3 Saponin -- 4.4 Terpene -- 4.5 Lipid -- 4.6 Carbohydrate -- 5. Production of secondary metabolites through plant tissue culture -- 6. Methods of secondary metabolites production -- 7. Conventional methods -- 8. Nonconventional methods -- 9. Genetic engineering using microbes -- 10. Precursor feeding -- 11. Biotransformation -- 12. Metabolic engineering -- 13. Conclusion and future perspectives -- References -- 5 - Role of endophytes in the production of secondary metabolites -- 1. Introduction -- 2. Types of endophytes -- 2.1 Bacterial endophytes -- 2.2 Fungal endophytes -- 3. Interaction of endophytes with the host plant -- 4. Production of the secondary metabolites by endophytes. , 5. Biosynthesis of secondary metabolites -- 6. Conclusion and future prospect -- References -- 6 - Trends in secondary metabolites production from plant sources -- 1. Introduction -- 2. Recent developments in the process of producing secondary metabolites -- 3. Secondary metabolites production derived from medicinal plants by using tissue cultures -- 4. Recent developments in secondary metabolites production by higher plants -- 5. Production of secondary metabolites using organ cultures -- 6. The addition of a precursor to help improve the secondary metabolites production -- 7. Elicitation of products developed in vitro -- 8. Secondary metabolites source-hairy root cultures -- 9. Using hairy root culture with the purpose of secondary metabolites production by means of genetic manipulation -- 10. Endophytes play an important part in the in vitro secondary metabolites production -- 11. Increasing production of secondary metabolites via scaling of bioreactors -- 12. Immobilization increasing the accumulation of secondary metabolites on a larger scale -- 13. Tissue cultures production responsible for interesting pharmaceutical products -- 14. Taxol -- 15. Morphine and codeine -- 16. Diosgenin -- 17. l-DOPA -- 18. Capsaicin -- 19. Camptothecin -- 20. Berberine -- 21. The metabolic pathway engineering and generation of secondary metabolites -- 22. Engineering yeast metabolic pathways to produce plant secondary metabolites -- 23. Yeast's contribution to the production of flavonoids -- 24. Yeast is responsible for the production of terpenoids -- 25. Yeast's role in the production of alkaloids derived from plants -- 26. Conclusion -- References -- 7 - Elicitation of secondary metabolites from plants -- 1. Introduction -- 2. Classification of elicitors -- 2.1 Biotic elicitors -- 2.2 Abiotic elicitors -- 2.2.1 Hormonal elicitors -- 2.2.1.1 Jasmonic acid. , 2.2.1.1 Jasmonic acid -- 2.2.1.2 Salicylic acid -- 2.2.1.2 Salicylic acid -- 2.2.1.3 Hormones of a different kind -- 2.2.1.3 Hormones of a different kind -- 2.2.1.4 Brassinosteroids -- 2.2.1.4 Brassinosteroids -- 2.2.1.5 Abscisic acid -- 2.2.1.5 Abscisic acid -- 2.2.1.6 SM auxins -- 2.2.1.6 SM auxins -- 2.2.2 Inorganic elicitors (chemical) -- 2.2.2.1 Heavy metals -- 2.2.2.1 Heavy metals -- 2.2.2.2 Effects of undernourishment and toxic metals on root exudate secretion -- 2.2.2.2 Effects of undernourishment and toxic metals on root exudate secretion -- 2.2.3 Elicitors of a physical nature -- 2.2.3.1 Radiation from UV-B rays -- 2.2.3.1 Radiation from UV-B rays -- 2.2.3.2 Salt concentration -- 2.2.3.2 Salt concentration -- 2.2.3.3 The strain of a drought -- 2.2.3.3 The strain of a drought -- 2.2.3.4 Stress caused by heat -- 2.2.3.4 Stress caused by heat -- 3. Mechanism of elicitation in plant cells -- 4. Elicitors that are being used at the present time -- 5. New methods to boost SM production depending on the elicitor signaling pathways -- 6. Summary and remarks -- References -- 8 - Genetic manipulation for secondary metabolite production -- 1. Introduction -- 2. Genes involved in the biosynthesis -- 3. Genes that act as regulators -- 4. Genes involved in the production of indole alkaloids -- 5. Regulatory genes involving indole alkaloids -- 6. Isoquinoline alkaloids -- 7. Pyrrolidine alkaloids and tropane alkaloids -- 8. Terpenoids -- 9. Carotenoids -- 10. Benzoic acid derivatives -- 11. Cyanogenic glucosides -- 12. Stilbene phytoalexins are introduced in transgeneic plants -- 13. Plant protection and plant breeding use of the phytoalexin technology -- 14. Modification of secondary plant metabolism to produce functional food -- 15. Disease resistance is achieved through engineering phytoalexin pathways -- 16. Final thoughts and summaries -- References. , 9 - Scaling up of secondary metabolite production -- 1. Introduction -- 2. Production of secondary metabolites -- 3. Use of organized cultures and metabolic engineering for secondary metabolite production -- 4. Application of hairy roots in secondary metabolites production -- 5. Metabolite engineering in secondary metabolite production -- 6. Engineering considerations in large-scale production of biomass -- 7. Strategies to improve productivity -- 7.1 Screening and selection, medium optimization -- 7.2 Scale-up of plant cell suspension culture: Features of plant cell culture in bioreactors -- 7.3 Application of different bioreactors in secondary metabolites production -- 7.4 Differentiated cells -- 7.5 Immobilized cells -- 7.6 Elicitation -- 7.7 Metabolic engineering -- 7.8 Examples of plant genes in plants or plant cells -- 7.9 Microbial genes in plants or plant cells -- 7.10 Plant genes in microorganisms -- 8. Conclusion -- 9. Future perspective -- References -- Further reading -- 10 - Metabolic engineering and production of secondary metabolites -- 1. Introduction -- 2. Secondary metabolites -- 2.1 Terpenes -- 2.1.1 Diterpenes -- 2.1.2 Triterpenes (C30) -- 2.1.3 Tetraterpenes (C40) -- 2.1.4 Polyterpenes (C5) -- 2.1.4.1 Creation of terpenes -- 2.1.4.1 Creation of terpenes -- 2.2 Phenolics -- 2.2.1 Flavanoinds -- 2.2.2 Flavonols -- 2.2.3 Isoflavonoides -- 2.2.4 Isoflavone coumarins -- 2.2.5 Furano-coumarins -- 2.3 Nonflavonoids -- 2.3.1 Hydroxycinnamates -- 2.4 Alkaloids -- 2.4.1 Alkaloids of quinolizidine -- 2.4.2 Alliinins -- 3. Metabolic engineering -- 3.1 Metabolic engineering for plant secondary metabolites production -- 4. Secondary metabolite production pathways -- 4.1 Shikimic-acid (shikimate) pathway -- 4.2 Malonic-acid (malonate/acetate) pathway -- 4.3 Methylerythritol-phosphate pathway. , 4.4 Agrobacterium: A unique metabolic engineer of plant.
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  • 9
    Online Resource
    Online Resource
    Milton :Taylor & Francis Group,
    Keywords: Food. ; Electronic books.
    Description / Table of Contents: Rapid industrialization and intensive increase in agricultural activities has decreased the soil quality, fertility, thereby adversely impacting environment, which is a serious concern globally. This book will be covering various roles of biological as well as physico-chemical management technologies for environment sustainability.
    Type of Medium: Online Resource
    Pages: 1 online resource (385 pages)
    Edition: 1st ed.
    ISBN: 9781000735956
    DDC: 363.705
    Language: English
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  • 10
    Online Resource
    Online Resource
    Singapore :Springer Singapore Pte. Limited,
    Keywords: Environmental engineering. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (271 pages)
    Edition: 1st ed.
    ISBN: 9789811568879
    Series Statement: Lecture Notes in Civil Engineering Series ; v.93
    DDC: 628
    Language: English
    Note: Intro -- Contents -- About the Editors -- Design and Simulation of Vertical Handover Algorithm for Intelligent Transport System Using Analytic Hierarchy Process -- 1 Introduction -- 2 Analytic Hierarchy Process -- 3 Design Methodology of Vertical Handover -- 4 Simulation Results for Voice Application -- 5 Conclusion -- References -- Particulate Matter Emission Assessment and Future Outlook Through Air Dispersion Model for Sustainable Development Planning in an Inland City in Central Maharashtra, India -- 1 Introduction -- 1.1 Study Area -- 2 Methodology -- 2.1 Emission Inventory -- 2.2 Dispersion Modelling -- 2.3 Ambient Air Quality Monitoring at Receptor -- 3 Result -- 3.1 Emission Inventory -- 3.2 Disperssion Modelling -- 3.3 Monitoring -- 4 Discussion -- 4.1 Point Source Mitigation Action Plan -- 4.2 Area Sources -- 4.3 Line Sources -- 5 Conclusion -- References -- Assessment on Prevention of Groundwater Contamination -- 1 Introduction -- 2 Illustrations -- 2.1 Groundwater: Its Contamination, Pollution, and Its Prevention in India. By Kunjlata Lal, Assistant Professor, Dept. of Education Ranchi Women's College, Ranchi, Jharkhand [5] -- 2.2 Groundwater Arsenic Contamination in Bangladesh: Causes, Effects, and Remediation -- 2.3 Groundwater Pollution and Remediation -- 2.4 Contamination of Groundwater Systems in the US and Canada by Enteric Pathogens, 1990-2013 -- 2.5 Drastic Approach to Controlling Groundwater Pollution -- 2.6 Possible Methods of Preventing Groundwater Contamination at Landfill Sites -- Case Studies from Nepal -- 3 Conclusion -- References -- Sensitivity Study on the Classical Biofilm Model Using a Simplified Solution Method -- 1 Introduction -- 2 Objective -- 2.1 Materials and Methods -- 2.2 Results and Discussion -- 3 Conclusions -- References -- Risk of Extinction of Species in an Ecological System: Estimation and Analysis. , 1 Introduction -- 2 Joint Probability Distribution of Prey-Predator in a Two Dimensional Ecological Model -- 3 Derivation of Joint Probability Distribution -- 3.1 Marginal Distribution of Prey -- 4 Derivation of Difference Equation for Persistence Time of Prey -- 5 Application to Predator-Prey Models -- 6 Result and Discussion -- References -- An Experimental Study on Integrated Power-Free Shock Electrodialysis for Desalination -- 1 Introduction -- 2 Objectives -- 3 Materials and Methodology -- 3.1 Constituents of Synthetic Seawater -- 3.2 Desalinator Setup -- 3.3 Power Generator Setup -- 3.4 Experimental Procedure -- 4 Results and Discussions -- 4.1 Effect of Time and Voltage on the Electrodialysis Process -- 4.2 Effect of Voltage on % Removal of TDS -- 4.3 Effect of Voltage on EC Reduction -- 4.4 Power Consumption at Different Voltage -- 4.5 Optimization of Electrodialysis Process Using Response Surface Methodology (RSM) -- 4.6 Experimental Procedure for Optimization -- 4.7 Summary of Responses for Synthetic Seawater Sample -- 4.8 Electrodialysis on Synthetic Seawater at Different NaCl Molar Concentration -- 4.9 Results of Power Generation -- 5 Conclusion -- References -- Brassica Juncea (L.) Czern. (Indian Mustard): A Potential Candidate for the Phytoremediation of Mercury from Soil -- 1 Introduction -- 2 Materials and Method -- 3 Results and Discussion -- 3.1 Hg Concentration in Plant's Tissues (Root, Stem, and Leaf) -- 3.2 Volatilization of Hg from Hg-Treated Blank Soil at 30th, 60th, and 90th Day of Exposure -- 4 Conclusions -- References -- Stabilization of Expansive Soil Using Saw Dust -- 1 Introduction -- 2 Objectives of Study -- 3 Expansive Soil -- 4 Laboratory Studies -- 4.1 Standard Proctor Compaction Test -- 5 Results and Discussion -- 5.1 Effect of Saw Dust on Proctor Compaction Tests. , 5.2 Effect of Saw Dust on Atterberg's Limits of Soil -- 5.3 Effect of Saw Dust on Plasticity Index -- 5.4 Effect of Saw Dust on CBR Tests Result -- 5.5 Effect of Saw Dust on Direct Shear Test -- 6 Conclusion -- References -- Analysing the Influence of Groundwater Exploitation on Its Quality in Kolkata -- 1 Introduction -- 2 Location of the Study Area -- 3 Methodology -- 4 Results and Discussion -- 5 Conclusions -- References -- Efficacy Evaluation of Conventional Water Treatment Process and THMs Modeling in Drinking Water of Five Cities in India -- 1 Introduction -- 2 Material and Methods -- 2.1 Sample Collection -- 2.2 Analytical Methods -- 2.3 Predictive Modeling Approaches of THMs -- 3 Result and Discussion -- 3.1 Water Quality Status and Distribution of THMs Precursors -- 3.2 Efficacy Evaluation of Existing Treatment System for Removal of THMs Precursors -- 3.3 Modeling of THMs Formation Using SVM -- 3.4 Validation of SVM Model -- 4 Conclusion -- References -- Study of Water Quality Index to Ascertain the Suitability of Surface Water for Domestic Purposes -- 1 Introduction -- 2 Materials and Methods -- 3 Theoretical Analysis -- 4 Results and Discussion -- 5 Conclusion -- References -- Evaluation of Anthropogenic-Driven Water Pollution Effects in an Urban Freshwater Resource Using Integration Pollution Index Method -- 1 Introduction -- 2 Study Area -- 3 Materials and Methods -- 4 Results and Discussions -- 5 Conclusion -- References -- Improved Sequential Approach for Hybrid Bioleaching of Metals from E-Waste -- 1 Introduction -- 2 Materials and Methods -- 2.1 E-Waste Collection and Processing -- 2.2 Bacteria and Culture Conditions -- 2.3 Biological Oxidation of Ferrous Iron -- 2.4 Hybrid Bioleaching -- 2.5 Analytical Procedure -- 3 Results and Discussion. , 3.1 Metallic Content and Surface Morphology of Comminuted PCB Before and After Hybrid Bioleaching -- 3.2 Variation in Fe2+ and Fe3+ Concentrations, pH, and ORP Before and After PCB Addition -- 3.3 Metal Extraction Following Sequential Approach for Hybrid Bioleaching -- 4 Conclusions -- References -- Green Energy Based Low Cost Smart Indoor Air Quality Monitoring and Purifying System -- 1 Introduction -- 2 Literature Review -- 2.1 Existing Works -- 3 Principle of Working -- 3.1 Monitoring Unit -- 3.2 Control Unit -- 4 Results and Discussions -- 5 Conclusion -- References -- Degradation of Phenol Using Batch-Fluidization Process by Transition Metal Impregnated Red Mud as Modified Catalyst in Heterogeneous Fenton Process -- 1 Introduction -- 2 Materials and Methods -- 3 Preparation of N-RM and RM-Co Catalyst -- 4 Experimental Set-up -- 5 Results and Discussion -- 5.1 N-RM and RM-Co Characterization -- 6 Degradation Study -- 7 Conclusions -- References -- Application of Low-Cost Air Quality Monitoring Sensor to Assess the Exposure of Ambient Air Pollution Due to PM2.5 and PM10 -- 1 Introduction -- 2 Materials and Methods -- 2.1 The Design of the Study and Sites -- 2.2 Low-Cost Monitoring Solution -- 2.3 Data Collection, Extraction, and Processing -- 3 Results -- 3.1 Validation Experiment -- 3.2 Spatial Variation -- 3.3 Diurnal Variation -- 3.4 Temporal Variation -- 3.5 Most Exposed Zone -- 4 Discussion -- 5 Conclusion -- References -- Estimation of Greenhouse Gases in the Ambient Air -- 1 Introduction -- 1.1 Emission from Wastewater Treatment Plant (WWTP) -- 1.2 Emission from Irrigated Rice Fields (IRF) -- 1.3 Emission from Constructed Wetlands (CWs) -- 2 Methodology -- 2.1 Wastewater Treatment Plant (WWTP) -- 2.2 Irrigated Rice Fields (IRF) -- 2.3 Constructed Wetlands (CWs) -- 3 Result and Discussion -- 3.1 Action Plan -- 4 Conclusion -- References. , Indoor Air Pollution at Restaurant Kitchen in Delhi NCR -- 1 Introduction -- 2 Methodology -- 3 Result and Discussion -- 4 Conclusion -- References -- Determination of SCS Runoff Curve Number and Landuse Characteristics of Khowai River Catchment, Tripura, India -- 1 Introduction -- 2 Methods -- 3 Results and Discussion -- 4 Conclusion -- References -- Degradation of Plastics Causing Pollution Using Bacteria for Improvement of Freshwater Fish Cultivation -- 1 Introduction -- 2 Materials and Methods -- 3 Summary and Conclusion -- References -- Assessment and MLR Modeling of Traffic Noise at Major Urban Roads of Residential and Commercial Areas of Surat City -- 1 Introduction -- 2 Materials and Methodology -- 3 Data Analysis and Results -- 3.1 Bhatar Road (Flexible Pavement) -- 3.2 Swami Vivekananda Marg (Flexible Pavement) -- 3.3 Big Bazaar-Vesu Road (Rigid Pavement) -- 4 Model Developments -- 4.1 For All Three Roads -- 5 Results and Discussion -- 6 Conclusion and Recommendations -- References -- A Review on the Advanced Techniques Used for the Capturing and Storage of CO2 from Fossil Fuel Power Plants -- 1 Introduction -- 2 Emissions of CO2 from Fossil Fuel Power Plant -- 3 Cost and Efficiency -- 4 Conclusion -- References -- Assessment and Characterization of Air Pollution Due to Vehicular Emission Considering the AQI and LOS of Various Roadways in Kolkata -- 1 Introduction -- 2 Literature Review -- 2.1 Data Collection -- 2.2 Factor Analysis -- 2.3 Principle Component Analysis -- 2.4 Model Development Using Ordered Logit Model -- 2.5 Case Study: (Amherst Street) -- 3 Conclusion -- References -- Advent of Graphene Oxide and Carbon Nanotubes in Removal of Heavy Metals from Water: A Review -- 1 Introduction -- 2 Carbon Nanotubes -- 3 Graphene Oxide -- 4 Conclusion -- References. , Removal of Arsenic V+ contaminant by Fixed Bed Column Study by Graphene Oxide Manganese Iron (GO-Mn-Fe) Nano Composite-Coated Sand.
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