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  • Arabian Sea  (1)
  • Inositol 1,4,5-triphosphate  (1)
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  • 1
    Publication Date: 2024-01-30
    Description: 〈title xmlns:mml="http://www.w3.org/1998/Math/MathML"〉Abstract〈/title〉〈p xmlns:mml="http://www.w3.org/1998/Math/MathML" xml:lang="en"〉Marine heatwaves are known to have a detrimental impact on marine ecosystems, yet predicting when and where they will occur remains a challenge. Here, using a large ensemble of initialized predictions from an Earth System Model, we demonstrate skill in predictions of summer marine heatwaves over large marine ecosystems in the Arabian Sea seven months ahead. Retrospective forecasts of summer (June to August) marine heatwaves initialized in the preceding winter (November) outperform predictions based on observed frequencies. These predictions benefit from initialization during winters of medium to strong El Niño conditions, which have an impact on marine heatwave characteristics in the Arabian Sea. Our probabilistic predictions target spatial characteristics of marine heatwaves that are specifically useful for fisheries management, as we demonstrate using an example of Indian oil sardine (〈italic〉Sardinella longiceps〈/italic〉).〈/p〉
    Description: Plain Language Summary: Marine heatwaves (MHWs) are prolonged extreme events associated with exceptionally high ocean water temperatures. Such events impose heat stress on marine life, and thus predicting such events is beneficial for management applications. In this work we show that the occurrence of MHWs in summer in the Arabian Sea can be skilfully predicted seven month in advance. Our prediction system benefits from the information of sea surface temperature anomalies in the eastern Pacific Ocean in the preceding winter, among other aspects. Our predictions suggest potential for using climate information in fisheries management in this region.〈/p〉
    Description: Key Points: 〈list list-type="bullet"〉 〈list-item〉 〈p xml:lang="en"〉Summer marine heatwaves in the Arabian Sea are predictable seven months in advance〈/p〉〈/list-item〉 〈list-item〉 〈p xml:lang="en"〉The prediction skill in summer is mainly associated with a preceding El Niño event in winter〈/p〉〈/list-item〉 〈list-item〉 〈p xml:lang="en"〉Probabilistic predictions of Arabian Sea area under heatwave can be tailored to benefit fisheries〈/p〉〈/list-item〉 〈/list〉 〈/p〉
    Description: DFG
    Description: Universität Hamburg http://dx.doi.org/10.13039/501100005711
    Description: Cedars‐Sinai Medical Center http://dx.doi.org/10.13039/100013015
    Description: Marine Institute http://dx.doi.org/10.13039/501100001627
    Description: Copernicus Climate Change Service
    Description: Aigéin, Aeráid, agus athrú Atlantaigh
    Description: EU
    Description: http://dx.doi.org/10.7289/V5SQ8XB5
    Description: http://hdl.handle.net/hdl:21.14106/f2fdc61b13828ed5284f4e4ab41e63f8a84c6e52
    Description: http://hdl.handle.net/hdl:21.14106/27e73ed39cd59d2033e018a494e342383db53a0b
    Keywords: ddc:551.46 ; Arabian Sea ; marine heatwaves
    Language: English
    Type: doc-type:article
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 430 (1995), S. 954-963 
    ISSN: 1432-2013
    Keywords: Ca2+ influx ; Inositol 1,4,5-triphosphate ; Ca2+-activated Cl− current ; Xenopus oocyte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The relationship between capacitative Ca2+ influx and activation of Ca2+-dependent Cl− channels was monitored in intactXenopus oocytes following stimulation of 5-hydroxytryptamine (5-HT) receptors, through the activity of Ca2+-dependent Cl− channels using the double-electrode voltage-clamp technique. Under voltage-clamp conditions, 5-HT evoked a rapid transient inward current followed by a slowly developing secondary inward current. The secondary current reflected depletion-activated Ca2+ entry. Hyperpolarising pulses evoked sustained Ca2+-dependent Cl− currents when applied during the transient inward current, but evoked hump-like currents which inactivated rapidly when applied during the secondary inward current. Hump currents arose from Ca2+ entering through the depletion-activated pathway. The hump currents inactivated with hyperpolarising pulses at 〈5-s intervals, and recovered monoexponentially with a time constant of around 8 s. Currents in response to hyperpolarising pulses during the transient current did not inactivate, suggesting that inactivation was associated with Ca2+ entry. When Ca2+ release evoked by inositol 1,4,5-triphosphate [Ins(1,4,5)P 3] was prevented by heparin injection, hyperpolarising pulses during Ca2+ ionophore application also generated hump currents that were dependent on external Ca2+, inactivated and recovered from inactivation with a similar time course as the humps following 5-HT treatment. Pretreatment with the Ca2+ adenosine 5′-triphosphatase (Ca2+ATPase) inhibitor thapsigargin reduced the rate of rise of the hump current, increased the time-to-peak of the current and slowed the rate of decay. Pharmacological interventions to disrupt the cytoskeleton reduced the amplitude of the hump current. It is suggested that, following hyperpolarisation in the presence of Ca2+ entry, the ensuing Ca2+ influx interacts with Cl− channels in a way that might reflect both Ca2+ inhibition of Ca2+ entry and clustering of Cl− channels in the plasma membrane.
    Type of Medium: Electronic Resource
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