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  • 1
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Analytical chemistry 51 (1979), S. 311-313 
    ISSN: 1520-6882
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 16 (1981), S. 0 
    ISSN: 1600-0765
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Sulcular penetration patterns of phenytoin (PHT) and albumin (BSA), in New Zealand white rabbits, were followed through the sulcular lining tissue, overlying gingiva, interposed connective tissue, proximating periosteum and blood over 180 minutes. The time course study revealed that a steady-state uptake of both molecules from the sulcus into the sulcular lining tissue was reached approximately 60 minutes after local tracer application. It was also found that PHT, after penetrating the sulcular lining tissue, was maintained at higher levels in gingiva than in other adjacent tissues while BSA levels were found highest in periosteum. Kinetic studies of these tissues demonstrated that sulcular tissue had a greater capacity for PHT than BSA and that uptake by this tissue had a capacity-limited characteristic. The other adjacent tissues and blood also showed capacity-limited characteristics probably reflecting uptake by the sulcular tissues. BSA degradation or PHT metabolism did not occur in any of these tissues or in serum.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 51 (1981), S. 0 
    ISSN: 1399-3054
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Notizen: The ability of intact primary roots of corn (Zea mays L. Bear Hybrid WF 9 × 38) to adapt to growth-inhibitory concentrations of auxin was studied using a highly sensitive position sensor transducer to measure growth. The timing, concentration dependence and temperature dependence of adaptation were studied as well as the time course of loss of adaptation upon removal of auxin. The rate of root elongation is inhibited 80% within 40 min after application of 10−7M IAA. Within 90 min growth rate begins to recover. For concentrations of IAA equal to or greater than 10−7M, recovery of growth rate (adaptation) is incomplete. Corn roots show a similar pattern of adaptation to the synthetic auxins NAA and 2,4-D. The Q10 for adaptation is high (3.2) and comparable to that for root growth (3.3). Upon removal of exogenous IAA, loss of adaptation occurs with full sensitivity to the hormone regained within 20 min.Based on the auxin specificity and the Q10 for adaptation it is concluded that adaptation occurs neither by a change in the auxin degradation capacity of the root nor by a diffusional redistribution of applied auxin. It is suggested that adaptation involves metabolic processes, perhaps a metabolically dependent alteration of the number or affinity of auxin binding sites.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 6 (1979), S. 0 
    ISSN: 1574-6968
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 11 (1981), S. 0 
    ISSN: 1574-6968
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Cancer chemotherapy and pharmacology 4 (1980), S. 263-266 
    ISSN: 1432-0843
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We have confirmed that doxorubicin induces irreversible changes in the nucleolar ultrastructure of myocardial cells of rats. Similar changes were not caused by an equal dose of the synthetic analogue, 5-iminodaunomycin. These results combined with previous and current comparative tests with this analogue, doxorubicin, and daunomycin suggest that 5-iminodaunomycin may serve as a less cardiotoxic anthracycline derivative.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Planta 148 (1980), S. 510-512 
    ISSN: 1432-2048
    Schlagwort(e): Auxin ; Cell wall pH ; Growth (roots) ; Proton flux and growth ; Root growth ; Zea
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract At concentrations inhibitory to the elongation of corn (Zea mays L.) roots, the auxins, indole-3-acetic acid (IAA) and α-naphthaleneacetic acid (α-NAA), cause an increase in the pH of the bathing medium; this increase occurs with an average latent period shorter than the latent period for the inhibitory effect of these auxins on elongation. Indole-2-carboxylic acid, an inactive structural analogue of IAA, and β-naphthaleneacetic acid, an inactive analogue of α-NAA, affect neither growth nor the pH of the medium. Since acid pH is known to promote and basic pH to inhibit root elongation, the data are consistent with the hypothesis that hormone-induced modification of cell-wall pH plays a role in the control of elongation of roots, as has been proposed for elongation of stems and coleoptiles.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
    ISSN: 1432-2048
    Schlagwort(e): Allium ; Calcium and gravitropism ; Morphactin ; Naphthylphthalamic acid ; Pisum (gravitropism) ; 2,3,5-Triiodobenzoic acid ; Zea (gravitropism)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Primary roots of maize (Zea mays L.) and pea (Pisum sativum L.) exhibit strong positive gravitropism. In both species, gravistimulation induces polar movement of calcium across the root tip from the upper side to the lower side. Roots of onion (Allium cepa L.) are not responsive to gravity and gravistimulation induces little or no polar movement of calcium across the root tip. Treatment of maize or pea roots with inhibitors of auxin transport (morphactin, naphthylphthalamic acid, 2,3,5-triiodobenzoic acid) prevents both gravitropism and gravity-induced polar movement of calcium across the root tip. The results indicate that calcium movement and auxin movement are closely linked in roots and that gravity-induced redistribution of calcium across the root cap may play an important role in the development of gravitropic curvature.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Planta 157 (1983), S. 150-157 
    ISSN: 1432-2048
    Schlagwort(e): Abscisic acid and root growth ; Acid efflux and root growth ; Aminoethoxyvinylglycine ; Gravitropism (root) ; Phaseic acid ; Pisum (root growth) ; Root growth (hormones) ; Zea (root growth)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Using an auxanometer and time-lapse cinematography we have studied the timing of abscisic acid (ABA) effects on elongation, gravitropic curvature, and hydrogen-ion efflux in several cultivars of maize (Zea mays L.). The effect of high concentrations (e.g. 0.1 mM) of ABA on root elongation is triphasic, including 1) a period of promotion lasting approximately 12 h, 2) a subsequent period of increasing inhibition lasting approximately 12h, and 3) gradual recovery to a rate within approximately 80% of the control rate. With lower concentrations of ABA (e.g. 0.1 μM) only the transient promotive phase is seen. Abscisic acid enhances ethylene biosynthesis in roots of maize but suppression of ethylene biosynthesis does not prevent the long-term inhibitory action of ABA on growth. Application of ABA (0.1 mM) to the upper surface of horizontally placed roots accelerates positive gravitropism. Application of ABA to the lower surface retards gravitropism and in some cases causes the roots to curve upward against the direction of gravity. These observations are consistent with our finding that the initial effect of ABA on root elongation is stimulatory. Since root gravitropism is rapid enough to be completed within the stimulatory phase of ABA action, the data argue against hypotheses of gravitropism based upon accumulation of ABA to inhibitory levels on the lower side of a hirizontal root.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Planta 136 (1977), S. 97-102 
    ISSN: 1432-2048
    Schlagwort(e): Acid growth ; Auxin ; Ethylene ; Fusicoccin ; Growth inhibition ; Lens ; Root growth
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Both acid pH (4.0) and fusicoccin (FC) strongly stimulate root elongation in intact lentil (Lens culinaris Med.) seedlings. FC-induced elongation is apparently mediated by FC-enhanced H+ secretion since the toxin induces massive secretion of H+ in these roots after a latent period of less than 5 min. Auxin (indole-3-acetic acid) strongly inhibits elongation in control roots as well as acid-induced and FC-induced root elongation. Treatment of apical root segments with auxin causes only a slight apparent uptake of H+ and has no inhibitory effect on FC-induced H+ secretion, whether the hormone is given before or after the toxin. Auxin induces ethylene production in excised roots of lentil but the latent period is at least 30 min while inhibition of root elongation by IAA is maximal within 30 min. It is concluded that the inhibitory action of auxin on acid-and fusicoccin-induced root elongation is a direct effect, independent of auxin-induced ethylene production or auxin-mediated modification of cell-wall pH.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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