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  • 1990-1994  (7)
  • 1994  (4)
  • 1991  (3)
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  • 1990-1994  (7)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Techniques in immuno-electron microscopy (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 21 (1994), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Normal skin was cryoprotected by submerging it in a mixture of 30% dimethylformamide (DMF) in PBS or RPMI. Subsequently it was frozen in liquid propane gas. Cryosubstitution was carried out at −90°C by using methanol to which uranyl acetate or osmium tetroxide were added. The tissue was embedded in either Lowicryl K4M at −40°C or in Epon at +60°C. The- tissue was evaluated by its overall preservation of ultras-tructural details and by its labeling intensity alter incubation with either anti-clesmoglein or anti-type VII collagen monoclonal antibodies. The mixture of DMF and PBS caused an electron-dense precipitate within the cell. The overall morphology was better in Epon-embedded material than in K4M-embedclecl material. However, the labeling was best in K4M material. Regardless of whether the tissue was embedded in Epon or K4M, the addition of osmium tetroxide markedly reduced the degree of labeling.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1994.tb00708.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Congenital self-healing reticulohistiocytosis – A benign Langerhans cell disease (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 21 (1994), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An-11-day old girl was seen with brownish nodular lesions scattered over (he body with emphasis on the face and seal). Several lesions had started lo involute. Tissue was studied by histopathology, immunohistopathology, routine electron microscopy, and immuno-electron microscopy using cryosubstitution and embedding in K4M. Immunohistopathology revealed that the cells of the dermal infiltrate were Langerhans cells. They expressed Leu 6 and HLA-DR. On routine electron microscopy no Birbeck granules were (bund in the dermal cells. Birbeck granules in epidermal Langerhans cells were deformed and often situated next to laminated dense bodies. The latter expressed Leu 6 and HLA-DR. on immuno-electron microscopy. It was concluded that congenital self-healing reticulohistiocytosis is a benign Langerhans cell disease in which Birbeck granules are transformed to laminated dense bodies and possibly degraded by lysosomal enzymes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1994.tb00692.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Larval fish production in the tidal River Elbe 1985–1986 (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 38 (1991), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: In 1985 and 1986 ichthyoplankton composition was studied during seven sampling series at 37 stations along the tidal Elbe and its tributary rivers between Hamburg harbour and the North Sea. The highest larval density was observed in May and April. No, or very few, larvae occurred from late summer to early spring. Smelt (59% on average of all samples) and twaite shad (20%) dominate in the freshwater region. Herring/sprat (17%) dominate in the estuary. All major spawning grounds are located along the southern shore. Smelt spawn further upstream 1 month earlier than twaite shad. Three percent of all larvae found were flounder. Most of them occurred upstream from the estuary in the R. Este and in other tributary rivers. It is not clear whether flounders are able to spawn in freshwater. Attention is drawn to the fact that an unknown but probably very high percentage of the ichthyoplankton is entrained by local power plants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.1991.tb03622.x
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  • 4
    Electronic Resource
    Electronic Resource
    Avoidance of oxygen-poor zones by fish in the Elbe River (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of applied ichthyology 7 (1991), S. 0 
    Details
    ISSN: 1439-0426
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: For three selected weeks in July, August, and October 1985, catches from anchor net vessels at ten stations along the tidal Elbe River (northern Germany) were analyzed and related to oxygen conditions in the river. The oxygen concentrations decreased from an average of 6.6 ml/L in the estuary to an average of 1.4 mg/L upstream. Fish were found to be concentrated downstream from the low-oxygen zone and at the entrance to a shallow side arm of the main stream. Highest catches of eel were made where oxygen levels were in the range of 1.2–3 mg/L, highest catches of flounder at 3–4 mg/L, and highest catches of juvenile and adult smelt in areas with more than 5 mgO2/L. Such a situation enables fishermen to make extraordinarily high catches. It is concluded that despite high levels of toxicants, the tidal Elbe still offers living conditions adequate for the mass of fish species as long as there is a sufficient supply of oxygen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0426.1991.tb00524.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Medikamentöse Strategien bei unter Antidepressiva therapierefraktären Depressionen (1991)
    Springer
    Journal of molecular medicine 69 (1991), S. 413-415 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01647417
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  • 6
    Electronic Resource
    Electronic Resource
    Negative symptoms in schizophrenia: considerations for clinical trials (1994)
    Springer
    Psychopharmacology 115 (1994), S. 221-228 
    Details
    ISSN: 1432-2072
    Keywords: Schizophrenia ; negative symptoms ; clinical trials ; psychiatric status rating scales ; neuroleptics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There is little agreement about the methodology of clinical trials of antipsychotic drugs in patients with negative symptoms. A literature review revealed wide variation in experimental design, rating scales and study duration. This reflects differing views as to the definition and response to treatment of negative symptoms. Some degree of standardization would improve comparability of studies and aid the development of new compounds. Patients included in such studies should have displayed negative symptoms for at least 6 months. Depressive symptoms, positive schizophrenic symptoms and extrapyramidal signs may all influence or be confused with negative symptoms and may respond to treatment; they should be at a low level at baseline and should be measured during the study period. Studies should last at least 8 weeks. Several scales are available for measuring negative symptoms and are reviewed; a global impression score should be used additionally.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02244775
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  • 7
    Electronic Resource
    Electronic Resource
    Doubly-differential ionization cross sections of positron impact on argon (1994)
    Springer
    Hyperfine interactions 89 (1994), S. 133-140 
    Details
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We report the first measurement of doubly-differential ionization cross sections for positron impact on argon atoms. Energy- and angle-resolved measurements of ejected electrons in time correlation with the produced and detected ions have been performed. Corresponding measurements with incident electrons were made for comparison. With positrons and electrons as primary particles of 100 eV energy and ejected electrons of 15 eV, our measurements were extended over electron-emission angles from 0
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02064503
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