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  • 11
    Electronic Resource
    Electronic Resource
    Carboxypeptidase M as a marker of macrophage maturation (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Immunological reviews 161 (1998), S. 0 
    Details
    ISSN: 1600-065X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary: During terminal maturation of blood monocytes (MO) into macrophages (MAC), a multitude of phenotypic and functional changes occur: cells increase in size and enhance their capacity for phagocytosis and tumor cytotoxicity, but decrease their ability for T-lymphocyte stimulation. The pattern of secreted cytokines is shifted as is the profile of surface antigens. The identity of the MAC maturation-associated antigen MAX.1/ MAX.11 with carboxypeptidase M (CPM), a phosphoinositollinked endopeptidase, was recently described, CPM is able to process a multitude of different substrates, among them immunologically important peptides such as bradykinin, anaphylatoxins and enkephalins. It was previously shown to be expressed in placenta, lung and kidney. CPM as detected by MAX. 1/11 shows a strong expression on MO-derived MAC in vitro and on MAC in vivo accompanying T-lymphocyte activation such as during allogeneic transplant rejection or allergic alveolitis. In contrast, its expression is suppressed on MAC by some types of tumor cells, A synchronous expression of CPM together with MAC cytotoxic function makes a functional relationship very well possible. However, the biological importance of CPM expression on MAC in vivo is difficult to predict, since a wide range of biologically active peptides are substrates for CPM, and the relevance for most of those peptides to be processed by CPM during an immune reaction is only poorly understood at present.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-065X.1998.tb01576.x
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    Paper (German National Licenses)
    Fulltext
  • 12
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    Isotope analysis and heat flow measurements of Maria S. Merian cruise MSM21/4 on the western Svalbard margin (2014)
    PANGAEA
    In:  Supplement to: Berndt, Christian; Feseker, Tomas; Treude, Tina; Krastel, Sebastian; Liebetrau, Volker; Niemann, Helge; Bertics, Victoria J; Dumke, Ines; Dünnbier, Karolin; Ferre, Benedicte; Graves, Carolyn; Gross, Felix; Hissmann, Karen; Hühnerbach, Veit; Krause, Stefan; Lieser, Kathrin; Schauer, Jürgen; Steinle, Lea (2014): Temporal constraints on hydrate-controlled methane seepage off Svalbard. Published Online January 2 2014, Science, https://doi.org/10.1126/science.1246298
    Details
    Publication Date: 2023-03-03
    Description: Methane hydrate is an ice-like substance that is stable at high-pressure and low temperature in continental margin sediments. Since the discovery of a large number of gas flares at the landward termination of the gas hydrate stability zone off Svalbard, there has been concern that warming bottom waters have started to dissociate large amounts of gas hydrate and that the resulting methane release may possibly accelerate global warming. Here, we can corroborate that hydrates play a role in the observed seepage of gas, but we present evidence that seepage off Svalbard has been ongoing for at least three thousand years and that seasonal fluctuations of 1-2°C in the bottom-water temperature cause periodic gas hydrate formation and dissociation, which focus seepage at the observed sites.
    Keywords: Center for Marine Environmental Sciences; GEOMAR; Helmholtz Centre for Ocean Research Kiel; MARUM
    Type: Dataset
    Format: application/zip, 29 datasets
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    DATA PANGAEA
  • 13
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    Solid phase geochemistry of sediments from ROV push cores during Pourquoi Pas ? cruise INDEX2016, Hydrothermal Vent Outlet in the Kairei Field (2021)
    PANGAEA
    Details
    Publication Date: 2023-04-24
    Description: Deep-sea sediment samples were taken from the (wider) Kairei hydrothermal field area (25°S, 70°E) as well as a remote site (26°S, 71°E) in the Indian Ocean during the INDEX cruise 2016 with the N/O Pourquoi pas? (Ifremer, France). Push core samples from different areas of the Kairei vent field, as well as a sample from the remote site (~200 km south-east from the Kairei), were recovered with the help of the ROV VICTOR 6000 (Ifremer, France). All subsampling steps were carried out shipboard at 4 °C. With sterile syringes (nozzles removed) 3 ml of 2 cm layers of sediment were transferred into sterile falcon tubes for DNA extraction and stored at –80 °C. The remaining sediment was cut into 2 cm slices, freeze-dried, and partially milled to 〈75 mm for geochemical analyses. The sediment was analyzed for carbon chemistry, i.e. total organic carbon (TOC) and total inorganic carbon (TIC) with routine standard methods (IR-detection after combustion, ISO 10694, LECO CS 230 analyzer). Elemental composition of Kairei sediments was estimated by the accredited Actlab Laboratories, Canada (Multimethod mix called Ultratrace 3 program, using INAA, 4-Acid Digestion, ICP-OES, and ICP-MS). Sediments from the remote station were analyzed by routine WD-XRF after fusion with Li-Metaborate/Li-Bromide (XRF spectrometers Philips PW 2400 und Philips PW 1480).
    Keywords: 16S rRNA gene tags; Aluminium oxide; Area/locality; Calcium oxide; Carbon, carbonate; Carbon, organic; Carbon, total; Depth, bottom/max; DEPTH, sediment/rock; Depth, top/min; Element Analyser CS, LECO CS 230; Event label; geochemistry of porewaters; hydrothermal vent; INDEX2016; INDEX2016_12ROV; INDEX2016_20ROV; Indian Ocean; Iron oxide, Fe2O3; Kairei field; Magnesium oxide; Manganese oxide; metalliferous sediments; Phosphorus pentoxide; Potassium oxide; Pourquoi Pas ? (2005); Sample code/label; Silicon dioxide; Sodium oxide; Sulfur, total; Titanium dioxide; VICTOR; Victor6000 ROV
    Type: Dataset
    Format: text/tab-separated-values, 628 data points
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    DATA PANGAEA
  • 14
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    Porewater geochemistry of sediments from ROV push cores during Pourquoi Pas ? cruise INDEX2016, Hydrothermal Vent Outlet in the Kairei Field (2021)
    PANGAEA
    Details
    Publication Date: 2023-03-02
    Description: Deep-sea sediment samples were taken from the (wider) Kairei hydrothermal field area (25°S, 70°E) as well as a remote site (26°S, 71°E) in the Indian Ocean during the INDEX cruise 2016 with the N/O Pourquoi pas? (Ifremer, France). Push core samples from different areas of the Kairei vent field, as well as a sample from the remote site (~200 km south-east from the Kairei), were recovered with the help of the ROV VICTOR 6000 (Ifremer, France). All subsampling steps were carried out shipboard at 4 °C. Porewater from push cores was extracted with rhizons (CSS, 5 cm Rhizosphere Research Products B.V., Netherlands) at a resolution of 2-3 cm, fixed with 1% HNO3 for trace element analyses and stored at 4 °C. With sterile syringes (nozzles removed) 3 ml of 2 cm layers of sediment were transferred into sterile falcon tubes for DNA extraction and stored at –80 °C. Concentrations of minor and trace elements Li, Al, Rb, Cs, Sr, Ba, V, Mn, Fe, Co, Ni, Cu, Zn, Ag, Cd, Tl, Pb, In, Sn, Sb, Bi, W, Mo, U, Au, As, and L were determined by highresolution ICP-SF-MS (Element XR, Thermo Scientific) after 25-fold dilution and spiking with Y and Re for internal standardization using appropriate mass resolution settings.
    Keywords: 16S rRNA gene tags; Aluminium; Antimony; Area/locality; Arsenic; Barium; Cadmium; Caesium; Cerium; Cobalt; Copper; DEPTH, sediment/rock; Europium; Event label; geochemistry of porewaters; hydrothermal vent; ICP-OES; ICP-SF-MS, Thermo Scientific, Element XR; INDEX2016; INDEX2016_12ROV; INDEX2016_20ROV; Indian Ocean; Ion chromatography; Iron; Kairei field; Lanthanum; Lead; Manganese; metalliferous sediments; Molybdenum; Neodymium; Nickel; Nitrate; Pourquoi Pas ? (2005); Praseodymium; Samarium; Sample code/label; Silica, dissolved; Silver; Thallium; Tin; Tungsten; Uranium; Vanadium; VICTOR; Victor6000 ROV; Zinc
    Type: Dataset
    Format: text/tab-separated-values, 942 data points
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    DATA PANGAEA
  • 15
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    U-Th isotope systematics and light stable isotope data of carbonate enriched sediments at MASOX and HyBIS sites (methane seepage off Svalbard) from JAGO dives during cruise Maria S. Merian MSM21/4 (2014)
    PANGAEA
    Details
    Publication Date: 2024-02-02
    Keywords: Age, dated; Age, error; Age model; Calculated; Carbonates; Depth, bottom/max; DEPTH, sediment/rock; Depth, top/min; Description; Error, absolute; Event label; JAGO; Latitude of event; Location; Longitude of event; Maria S. Merian; Mass spectrometer, Finnigan, MAT 253; MC-ICP-MS, isotope dilution; MSM21/4; MSM21/4_579-1; MSM21/4_597-1; non-silicates, total; North Greenland Sea; Sample code/label; Sample mass; Submersible JAGO; Thorium-230/Thorium-232 activity ratio; Thorium-230/Uranium-234 activity ratio; Thorium-232; Uranium-234/Uranium-238 activity ratio; Uranium-234/Uranium-238 activity ratio, error, absolute; Uranium-238; Uranium-238/Thorium-232 activity ratio; X-ray diffractometry (Philips PW1710); δ13C, carbonate; δ18O, carbonate
    Type: Dataset
    Format: text/tab-separated-values, 119 data points
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    DATA PANGAEA
  • 16
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    U-Th isotope systematics and light stable isotope data of carbonate enriched sediments at MASOX site (methane seepage off Svalbard) at sediment core MSM21/4_657-1 (2014)
    PANGAEA
    Details
    Publication Date: 2024-02-02
    Keywords: Age, dated; Age, error; Age model; Calculated; Carbonates; Depth, bottom/max; DEPTH, sediment/rock; Depth, top/min; Description; Error, absolute; GC; Gravity corer; Location; Maria S. Merian; Mass spectrometer, Finnigan, MAT 253; MC-ICP-MS, isotope dilution; MSM21/4; MSM21/4_657-1; non-silicates, total; North Greenland Sea; Sample code/label; Sample mass; Thorium-230/Thorium-232 activity ratio; Thorium-230/Uranium-234 activity ratio; Thorium-232; Uranium-234/Uranium-238 activity ratio; Uranium-234/Uranium-238 activity ratio, error, absolute; Uranium-238; Uranium-238/Thorium-232 activity ratio; X-ray diffractometry (Philips PW1710); δ13C, carbonate; δ18O, carbonate
    Type: Dataset
    Format: text/tab-separated-values, 281 data points
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    DATA PANGAEA
  • 17
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    Geochemical data from in-situ peeper sampling MSM21/4_647-1 (2019)
    PANGAEA
    Details
    Publication Date: 2024-02-02
    Description: Six peepers were deployed by the German submersible Jago in sediment of the methane seep area off northwestern Svalbard at the gas hydrate stability limit. Peeper 1 and 2 were deployed in a sulfur bacteria mat, Peeper 3 and 4 were in a siboglinid (pogonophoran) worm field, and Peeper 5 and 6 were at a gas vent. The distance between the three groups was about 1 meter. After 10 days incubation, peeper were retrieved and porewater solutes were measured in the peeper samples.
    Keywords: Alkalinity, total; Bromide; Chamber number; Chloride; DEPTH, sediment/rock; Geochemistry; Hydrogen sulfide; JAGO; Maria S. Merian; Methane; MSM21/4; MSM21/4_647-1; North Greenland Sea; Number; sediment porewater; Submersible JAGO; Sulfate; Svalbard
    Type: Dataset
    Format: text/tab-separated-values, 321 data points
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    DATA PANGAEA
  • 18
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    Geochemical and geomicrobiological data from gravity core MSM21/4_657-1 (2019)
    PANGAEA
    Details
    Publication Date: 2024-02-02
    Description: This gravity corer was taken in the methane seep area off northwestern Svalbard at the gas hydrate stability limit. Sediment was sampled to determine solutes of sediment porewater, sediment wet and dry parameters and microbial activity (sulfate reduction and anaerobic oxidation of methane).
    Keywords: Alkalinity, total; Ammonium; Bromide; Calcium carbonate; Carbon, inorganic, total; Carbon, organic, total; Carbon, total; Carbon/Nitrogen ratio; Chloride; Density; DEPTH, sediment/rock; GC; Geochemistry; Gravity corer; hydrates; Hydrogen sulfide; Maria S. Merian; Methane; Methane, oxidation rate, anaerobic; methane oxidation; MSM21/4; MSM21/4_657-1; Nitrite; Nitrogen, organic; North Greenland Sea; Porosity; Sulfate; Sulfate reduction rate; Sulfur, total; Svalbard; δ18O
    Type: Dataset
    Format: text/tab-separated-values, 289 data points
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  • 19
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    Marine ammonification and carbonic anhydrase activity induce rapid calcium carbonate precipitation (2018)
    Elsevier
    In:  Geochimica et Cosmochimica Acta, 243 . pp. 116-132.
    Details
    Publication Date: 2021-02-08
    Description: During Earth’s history, precipitation of calcium carbonate by heterotrophic microbes has substantially contributed to the genesis of copious amounts of carbonate sediment and its subsequent lithification. Previous work identified the microbial sulfur and nitrogen cycle as principal pathways involved in the formation of marine calcium carbonate deposits. While substantial knowledge exists for the importance of the sulfur cycle, specifically sulfate reduction, with regard to carbonate formation, information about carbonate genesis connected to the microbial nitrogen cycle is dissatisfactory. In addition to the established pathways for carbonate mineral formation, also the potential of microbial carbonic anhydrase, a carbonate-relevant, zinc-containing enzyme, is receiving currently increased attention. However, also in this field knowledge is scarce and fragmentary. Here we demonstrate microbial carbonate precipitation as a direct result of the interplay between the microbial nitrogen cycle and a microbially produced enzyme. Using Alcanivorax borkumensis as a model organism, our experiments depict precipitation of a peloidal carbonate matrix within days to weeks, induced by simultaneous ammonification and extracellular carbonic anhydrase activity. The precipitates show similar morphology, mineralogy, δ44/40Ca, and δ88/86Sr to analogs of modern carbonate peloids. The obtained Sr/Ca partition coefficient DSr showed no clear deviation from inorganic carbonate phases, indicating that microbially mediated carbonate precipitation, indeed, follows the principles of physico-chemical precipitation. The observed relative enrichment of the precipitates in zinc might help to constrain zinc variations in natural carbonate archives. Our study demonstrates that ammonification, due to intense microbial organic matter degradation, and carbonic anhydrase may play a substantial role for calcium carbonate precipitation in paleo- and recent shallow marine environments.
    Type: Article , PeerReviewed
    Format: text
    DOI: 10.1016/j.gca.2018.09.018
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    OceanRep: Article in a Scientific Journal - peer-reviewed
  • 20
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    Anaerobic microbial activity affects earliest diagenetic pathways of bivalve shells (2018)
    International Association of Sedimentologists
    In:  Sedimentology, 65 (4). pp. 1390-1411.
    Details
    Publication Date: 2021-02-08
    Description: The earliest diagenetic post-mortem exposure of biogenic carbonates at the sea floor and in the uppermost sediment column results in the colonization of hard-part surfaces by bacterial communities. Some of the metabolic redox processes related to these communities have the potential to alter carbonate shell properties, and hence affect earliest diagenetic pathways with significant consequences for archive data. During a three-month in vitro study, shell subsamples of the ocean quahog Arctica islandica (Linnaeus, 1767) were incubated in natural anoxic sediment slurries and bacterial culture medium of the heterotrophic Shewanella sediminisHAW-EB3. Bulk analyses of the liquid media from the Shewanella sediminis incubation revealed an over ten-fold increase in total alkalinity, dissolved inorganic carbon and ΩAragonite, and the alteration of the Mg/Ca, Mg/Sr and Sr/Ca ratios relative to control incubations without cultures. Ion ratios were most affected in the incubation with anoxic sediment, depicting a 25% decrease in Mg/Ca relative to the control. Shell sample surfaces that were exposed to both incubations displayed visible surface dissolution features, and an 8 wt% loss in calcium content. No such alteration features were detected in control shells. Apparently, alteration of shell carbonate properties was induced by microbially driven decomposition of shell intercrystalline organic constituents and subsequent opening of pathways for pore fluid-crystal exchange. This study illustrates the potential influence of benthic bacterial metabolism on biogenic carbonate archives during the initial stages of diagenetic alteration within a relatively short experimental duration of only three months. These results suggest that foremost the biological effect of bacterial cation adsorption on divalent cation ratios has the potential to complicate proxy interpretation. Results shown here highlight the necessity to consider bacterial metabolic activities in marine sediments for the interpretation of palaeo-environmental proxies from shell carbonate archives.
    Type: Article , PeerReviewed
    Format: text
    DOI: 10.1111/sed.12428
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    OceanRep: Article in a Scientific Journal - peer-reviewed
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