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  • 1
    Digitale Medien
    Digitale Medien
    Embryonic Expression of Fgf-6 Is Restricted to the Skeletal Muscle Lineage
    Amsterdam : Elsevier
    Developmental Biology 158 (1993), S. 549-554 
    Details
    ISSN: 0012-1606
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1006/dbio.1993.1212
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  • 2
    Digitale Medien
    Digitale Medien
    The effects of inositol trisphosphates and inositol tetrakisphosphate on Ca^2^+ release and Cl^- current pattern in the Xenopus laevis oocyte
    Amsterdam : Elsevier
    Experimental Cell Research 192 (1991), S. 352-365 
    Details
    ISSN: 0014-4827
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1016/0014-4827(91)90052-V
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  • 3
    Digitale Medien
    Digitale Medien
    Helical CT anatomy of pancreatic arteries (1996)
    Springer
    Abdominal imaging 21 (1996), S. 517-521 
    Details
    ISSN: 1432-0509
    Schlagwort(e): Key words: Pancreas, anatomy—Pancreas, computed tomography—Computed tomography, helical technology.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract. Background: To assess the frequency of visualization of pancreatic arteries in the arterial phase of helical computed tomography (CT). Methods: The visibility of pancreatic and peripancreatic arteries in helical CT images was evaluated in 20 consecutive patients who had no evidence of pancreatic disease. CT examinations were performed by using a continuously rotating CT scanner and intravenous injection of contrast media. The scans were taken 35 s after the start of injection and with a table speed of 3 mm/s. Images were reconstructed in 3-mm section increments. Results: Frequently visualized arteries were the gastroduodenal, anterior and posterior superior pancreaticoduodenal, and right gastroepiploic arteries. Infrequently visualized arteries were the dorsal pancreatic, pancreatica magna, caudal pancreatic, transverse pancreatic, and common, anterior, and posterior inferior pancreaticoduodenal arteries. Conclusion: Helical CT enabled us to recognize small pancreatic arteries, and the evaluation of these arteries should be considered in the staging of pancreatic carcinoma.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002619900117
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  • 4
    Digitale Medien
    Digitale Medien
    T2-weighted MR imaging for hepatic hemangiomas: comparison of breath-hold and non-breath-hold turbo spin-echo pulse sequences with phased-array multicoil (1998)
    Springer
    Abdominal imaging 23 (1998), S. 422-426 
    Details
    ISSN: 1432-0509
    Schlagwort(e): Key words: Angioma, gastrointestinal tract—Liver, MR—Liver neoplasms, MR—Magnetic resonance (MR), comparative studies—Magnetic resonance (MR), technique.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract. Background: We compared T2-weighted and heavily T2-weighted breath-hold turbo spin-echo (TSE) sequences with T2-weighted non-breath-hold TSE sequence to evaluate hepatic hemangiomas on magnetic resonance (MR) with a phased-array multicoil. Methods: Twenty-two patients with 27 hemangiomas were studied at 1.0-T scanner by using T2-weighted and heavily T2-weighted breath-hold TSE sequences (18 s each) and non-breath-hold T2-weighted TSE sequences with use of a phased-array multicoil. Images were quantitatively analyzed for tumor-to-liver signal-difference-to-noise ratios (SD/Ns) and tumor-to-liver signal intensity ratios (T/Ls) and qualitatively analyzed for tumor conspicuity and motion-induced image artifacts. Results: Quantitatively, T2-weighted breath-hold TSE images showed the highest SD/Ns among the three sequences, although the differences from the heavily T2-weighted breath-hold TSE sequence and the T2-weighted non-breath-hold TSE sequence were not statistically significant (p= 0.61 and 0.06, respectively). Heavily T2-weighted breath-hold TSE images showed the highest T/Ls among the three sequences. The differences from the T2-weighted breath-hold TSE sequence and the T2-weighted non-breath-hold TSE sequence were statistically significant (p 〈 0.001). Qualitatively, breath-hold TSE images were superior to non-breath-hold TSE images in terms of tumor conspicuity (p 〈 0.01) and motion artifacts (p 〈 0.01). Conclusion: T2-weighted breath-hold TSE sequence is superior to T2-weighted non-breath-hold TSE sequence in the evaluation of hepatic hemangiomas on MR with a phased-array multicoil.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002619900372
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  • 5
    Digitale Medien
    Digitale Medien
    Hepatic abnormalities related to blood flow: evaluation with dual-phase helical CT (1999)
    Springer
    Abdominal imaging 24 (1999), S. 340-356 
    Details
    ISSN: 1432-0509
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002619900512
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  • 6
    Digitale Medien
    Digitale Medien
    Neoplasms containing normal hepatic vessels: imaging features (2000)
    Springer
    Abdominal imaging 25 (2000), S. 602-606 
    Details
    ISSN: 1432-0509
    Schlagwort(e): Key words: Liver-neoplasms—CT-liver—Neoplasms— Liver-vessels.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Background: We investigated the incidence and imaging features of hepatic neoplasms containing normal hepatic vessels. Methods: Among 3183 patients with various hepatic neoplasms, we found nine patients with normal hepatic vessels traversing hepatic neoplasms. The presence of mass effect on the vessel traversing hepatic neoplasms was evaluated. Other suggestive findings of neoplasms such as altered hepatic contour, portal vein thrombosis, mass effect on extratumoral vessel, and bile duct dilatation were analyzed. Results: Thirteen hepatic vessels (nine hepatic veins and four portal veins) extended through hepatic neoplasms in nine patients. Undisturbed hepatic vessels within the neoplasms were found in five patients with either primary or metastatic hepatic neoplasm. In one patient with undisturbed hepatic vessels within the neoplasm, there were no associated abnormal findings such as biliary dilatation, change of hepatic contour, or any changes involving the vessels external to neoplasms. Conclusion: Although rare, various primary and secondary hepatic neoplasms can have normal hepatic vessels passing through them without mass effect. However, correct diagnosis in most neoplasms would be possible with careful examination of associated findings. RID="" ID="" 〈E5〉Correspondence to:〈/E5〉 J. K. Han
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1107/s002610000049
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  • 7
    Digitale Medien
    Digitale Medien
    Detection of pancreatic adenocarcinoma: relative value of arterial and late phases of spiral CT (1997)
    Springer
    Abdominal imaging 22 (1997), S. 199 -203 
    Details
    ISSN: 1432-0509
    Schlagwort(e): Key words: Computed tomography, technology—Pancreas, CT—Pancreatic adenocarcinoma, CT.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract. Background: Spiral computed tomography (CT) allows the pancreas to be imaged during peak contrast levels owing to the capability of fast data acquisition. The objective of this study was to evaluate the relative value of the arterial and late phases of spiral CT for detecting pancreatic adenocarcinomas. Methods: Twenty-two patients with pathologically proved pancreatic adenocarcinomas underwent two-phase spiral CT. The CT scans were performed with 5 mm collimation and 5 mm/s table speed. Images during the arterial and late phases were obtained at 30- and 180-second delays, respectively. The images of the arterial phase were compared with those of the late phase in terms of tumor conspicuity from surrounding pancreatic parenchyma and tumor detectability by means of a 3-point grading system: 1 (poor), 2 (fair), and 3 (good). Results: In terms of tumor conspicuity from surrounding pancreatic parenchyma, 16 lesions (73%) were good, 5 lesions (23%) were fair, and 1 lesion (4%) was poor during the arterial phase, whereas 6 lesions (27%) were good, 9 lesions (41%) were fair, and 7 lesions (32%) were poor during the late phase (p= 0.0007). The arterial phase was superior to the late phase in 16 patients (73%) and equal in 6 patients (27%). For tumor detectability, 18 lesions (82%) were good, 3 lesions (14%) were fair, and 1 lesion (4%) was poor during the arterial phase, whereas 10 lesions (45%) were good, 7 lesions (32%) were fair, and 5 lesions (23%) were poor during the late phase (p= 0.0033). For detectability, the arterial phase was superior to the late phase in 14 patients (64%) and equal in 8 patients (36%). Conclusion: The arterial phase of spiral CT is superior to the late phase, which is equivalent to conventional CT for detecting pancreatic adenocarcinoma.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002619900172
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  • 8
    Digitale Medien
    Digitale Medien
    Dysplastic nodules of the liver: imaging findings (1999)
    Springer
    Abdominal imaging 24 (1999), S. 250-257 
    Details
    ISSN: 1432-0509
    Schlagwort(e): Key words: Liver—Neoplasms—US—CT—MR.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Background: To verify characteristic features of hepatic dysplastic nodules at different imaging modalities. Methods: Twenty-eight patients with 37 dysplastic nodules of the liver (0.8–3.0 cm) underwent sonography (28 patients), computed tomography (CT; 24 patients), magnetic resonance (MR; 11 patients), and angiography (12 patients). Each nodule was analyzed for echogenicity, attenuation, signal intensity, and vascularity. Results: Echogenicity of nodules was high in 16 (43%), homogeneous in two (6%), and low in 19 (51%) of 37 nodules. Attenuation of nodules was high in one (7%), homogeneous in four (26%), and low in 10 (67%) of 15 nodules on the arterial-phase CT images; homogeneous in five (33%) and low in 10 (67%) of 15 nodules on the portal-phase CT images; and high in four (17%), homogeneous in six (26%), and low in 13 (57%) of 23 nodules on the delayed-phase CT images. Signal intensity of nodules was high in 15 (94%) and homogeneous in one (6%) of 16 nodules on T1-weighted MR images and was homogeneous in seven (44%) and low in nine (56%) of 16 nodules on T2-weighted MR images. Vascularity of nodules was avascular in 14 (88%) and slightly vascular in two (12%) of 16 nodules. Conclusions: Hepatic dysplastic nodules show diverse imaging characteristics with different imaging techniques; however, common imaging findings of hepatic dysplastic nodules are low echo, low attenuation, and high, low, or homogeneous intensity on T1- and T2-weighted MR, and avascularity.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002619900490
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  • 9
    Digitale Medien
    Digitale Medien
    Gastric adenoma with atypical appearance: findings on double-contrast barium study with histopathologic correlation (2000)
    Springer
    Abdominal imaging 25 (2000), S. 124-128 
    Details
    ISSN: 1432-0509
    Schlagwort(e): Key words: Stomach—Atypical—Adenoma—Depressed—Flat—Double-contrast barium study.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Background: To describe the radiologic findings of nonpolypoid gastric adenomas and to correlate them with pathologic findings. Methods: During a 9-year period, we reviewed 49 pure gastric adenomas in 43 patients with positive radiologic findings. Of these adenomas, seven with atypical polypoid appearance were retrospectively included in the study. We reviewed these findings with double-contrast barium study and correlated them with the pathologic findings. Results: Of seven nonpolypoid adenomas, four were depressed and three were flat at pathologic examination. All were diagnosed as early gastric carcinoma (five as type IIc, one as type IIb, one as type IIa + IIc) in upper gastrointestinal series. Three were located in the gastric angle, two in the lower body, and two in the antrum. Size ranged from 10 mm to approximately 25 mm (mean = 15 mm). Six lesions had nodular surface and five had convergency of the mucosal folds. A shallow depressed area was seen in six lesions. Conclusions: A considerable proportion of gastric adenomas presents as a depressed or flat lesion on double-contrast barium study because of histologic characteristics of decreased subjacent mucosa. Because the nonpolypoid adenoma has a greater potentional for malignancy, more precaution is needed during the follow-up of this uncommon lesion.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002619910029
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  • 10
    Digitale Medien
    Digitale Medien
    Preoperative evaluation of Klatskin tumor: accuracy of spiral CT in determining vascular invasion as a sign of unresectability (2000)
    Springer
    Abdominal imaging 25 (2000), S. 500-507 
    Details
    ISSN: 1432-0509
    Schlagwort(e): Key words: Bile ducts—Bile ducts, CT—Bile ducts, neoplasm.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Background: To assess the accuracy of spiral computed tomography (CT) in predicting the resectability of Klatskin tumor as determined by vascular invasion. Methods: Twenty-one consecutive patients with Klatskin tumor who had undergone laparotomy were included in this study. The preoperative thin-section (5-mm-thick) spiral CT scans of these patients were assessed for the surgical resectability of tumor by evaluating the vascular invasion. The criterion for vascular invasion indicating unresectability was the tumoral invasion of the proper hepatic artery or main portal vein or simultaneous invasion of one side of the hepatic artery and the other side of the portal vein. Results: All nine patients with tumors thought to be unresectable on the basis of CT findings had tumors that were unresectable at surgery (positive predictive value, 100%). Of 12 patients with tumors thought to be resectable, six had resectable tumors (negative predictive value, 50%). Spiral CT failed to detect small hepatic metastasis (n= 1), lymph node metastasis (n= 1), extensive tumor (n= 2) and variation of bile duct (n= 2), which precluded surgical resection. Conclusion: Spiral CT is a reliable method for detecting vascular invasion and unresectable tumors. However, it has limitations in detecting variations of the bile duct or the intraductal extent of tumor.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1107/s002610000081
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