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  • 1
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    Imaging seismic wave-fields with AlpArray and neighboring European networks (2021)
    Springer Berlin Heidelberg
    Details
    Publication Date: 2024-02-28
    Description: The AlpArray experiment and the deployment of Swath-D together with the dense permanent network in Italy allow for detailed imaging of the spatio-temporal imaging complexity of seismic wave-fields within the greater Alpine region. The distance of any point within the area to the nearest station is less than 30 km, resulting in an average inter-station distance of about 45 km. With a much denser deployment in a smaller region of the Alps (320 km in length and 140 km wide), the Swath-D network possesses an average inter-station distance of about 15 km. We show that seismogram sections with a spatial sampling of less than 5 km can be obtained using recordings of these regional arrays for just a single event. Multiply reflected body waves can be observed for up to 2 h after source time. In addition, we provide and describe animations of long-period seismic wave-fields using recordings of about 1300–1600 broadband stations for six representative earthquakes. These illustrate the considerable spatio-temporal variability of the wave-field’s properties at a high lateral resolution. Within denser station distributions like those provided by Swath-D, even shorter period body and surface wave features can be recovered. The decrease of the horizontal wavelength from P to S to surface waves, deviations from spherically symmetric wavefronts, and the capability to detect multi-orbit arrivals are demonstrated qualitatively by the presented wave-field animations, which are a valuable tool for educational, quality control, and research purposes. We note that the information content of the acquired datasets can only be adequately explored by application of appropriate quantitative methods accounting for the considerable complexity of the seismic wave-fields as revealed by the now available station configuration.
    Description: Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659
    Description: Christian-Albrechts-Universität zu Kiel (3094)
    Keywords: ddc:551.22 ; Seismology ; Wave-fields ; Animations ; Alps ; AlpArray ; Swath-D
    Language: English
    Type: doc-type:article
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    CITATION GEO-LEO
  • 2
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    Aftershock seismicity of the 27 February 2010 Mw 8.8 Maule earthquake rupture zone (2012)
    Elsevier
    In:  Earth and Planetary Science Letters, 317-318 . pp. 413-425.
    Details
    Publication Date: 2016-06-22
    Description: On 27 February 2010 the Mw 8.8 Maule earthquake in Central Chile ruptured a seismic gap where significant strain had accumulated since 1835. Shortly after the mainshock a dense network of temporary seismic stations was installed along the whole rupture zone in order to capture the aftershock activity. Here, we present the aftershock distribution and first motion polarity focal mechanisms based on automatic detection algorithms and picking engines. By processing the seismic data between 15 March and 30 September 2010 from stations from IRIS, IPGP, GFZ and University of Liverpool we determined 20,205 hypocentres with magnitudes Mw between 1 and 5.5. Seismic activity occurs in six groups: 1.) Normal faulting outer rise events 2.) A shallow group of plate interface seismicity apparent at 25–35 km depth and 50–120 km distance to the trench with some variations between profiles. Along strike, the aftershocks occur largely within the zone of coseismic slip but extend ~ 50 km further north, and with predominantly shallowly dipping thrust mechanisms. Along dip, the events are either within the zone of coseismic slip, or downdip from it, depending on the coseismic slip model used. 3.) A third band of seismicity is observed further downdip at 40–50 km depth and further inland at 150–160 km trench perpendicular distance, with mostly shallow dipping (~ 28°) thrust focal mechanisms indicating rupture of the plate interface significantly downdip of the coseismic rupture, and presumably above the intersection of the continental Moho with the plate interface. 4.) A deep group of intermediate depth events between 80 and 120 km depth is present north of 36°S. Within the Maule segment, a large portion of events during the inter-seismic phase originated from this depth range. 5.) The magmatic arc exhibits a small amount of crustal seismicity but does not appear to show significantly enhanced activity after the Mw 8.8 Maule 2010 earthquake. 6.) Pronounced crustal aftershock activity with mainly normal faulting mechanisms is found in the region of Pichilemu (~ 34.5°S). These crustal events occur in a ~ 30 km wide region with sharp inclined boundaries and oriented oblique to the trench. The best-located events describe a plane dipping to the southwest, consistent with one of the focal planes of the large normal-faulting aftershock (Mw = 6.9) on 11 March 2010.
    Type: Article , PeerReviewed
    Format: text
    DOI: 10.1016/j.epsl.2011.11.034
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    OceanRep: Article in a Scientific Journal - peer-reviewed
  • 3
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    A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis (2015)
    Oxford University Press
    Details
    Publication Date: 2015-10-23
    Description: Aims Retention of low-density lipoprotein (LDL) cholesterol beneath the arterial endothelium initiates an inflammatory response culminating in atherosclerosis. Since the overlying endothelium is healthy and intact early on, it is likely that LDL passes through endothelial cells by transcytosis. However, technical challenges have made confirming this notion and elucidating the mechanisms of transcytosis difficult. We developed a novel assay for measuring LDL transcytosis in real time across coronary endothelial cell monolayers; we used this approach to identify the receptor involved. Methods and results Murine aortas were perfused ex vivo with LDL and dextran of a smaller molecular radius. LDL (but not dextran) accumulated under the endothelium, indicating that LDL transcytosis occurs in intact vessels. We then confirmed that LDL transcytosis occurs in vitro using human coronary artery endothelial cells. An assay was developed to quantify transcytosis of DiI-LDL in real time using total internal reflection fluorescence microscopy. DiI-LDL transcytosis was inhibited by excess unlabelled LDL, while degradation of the LDL receptor by PCSK9 had no effect. Instead, LDL colocalized partially with the scavenger receptor SR-BI and overexpression of SR-BI increased LDL transcytosis; knockdown by siRNA significantly reduced it. Excess HDL, the canonical SR-BI ligand, significantly decreased LDL transcytosis. Aortas from SR-BI -deficient mice were perfused ex vivo with LDL and accumulated significantly less sub-endothelial LDL compared with wild-type littermates. Conclusion We developed an assay to quantify LDL transcytosis across endothelial cells and discovered an unexpected role for SR-BI. Elucidating the mechanisms of LDL transcytosis may identify novel targets for the prevention or therapy of atherosclerosis.
    Print ISSN: 0008-6363
    Electronic ISSN: 1755-3245
    Topics: Medicine
    Published by Oxford University Press
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  • 4
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    Shear wave splitting and shear wave splitting tomography of the southern Puna plateau (2014)
    Oxford University Press
    Details
    Publication Date: 2014-08-30
    Description: We have investigated the seismic anisotropy beneath the Central Andean southern Puna plateau by applying shear wave splitting analysis and shear wave splitting tomography to local S waves and teleseismic SKS, SKKS and PKS phases. Overall, a very complex pattern of fast directions throughout the southern Puna plateau region and a circular pattern of fast directions around the region of the giant Cerro Galan ignimbrite complex are observed. In general, teleseismic lag times are much greater than those for local events which are interpreted to reflect a significant amount of sub and inner slab anisotropy. The complex pattern observed from shear wave splitting analysis alone is the result of a complex 3-D anisotropic structure under the southern Puna plateau. Our application of shear wave splitting tomography provides a 3-D model of anisotropy in the southern Puna plateau that shows different patterns depending on the driving mechanism of upper-mantle flow and seismic anisotropy. The trench parallel a -axes in the continental lithosphere above the slab east of 68W may be related to deformation of the overriding continental lithosphere since it is under compressive stresses which are orthogonal to the trench. The more complex pattern below the Cerro Galan ignimbrite complex and above the slab is interpreted to reflect delamination of continental lithosphere and upwelling of hot asthenosphere. The a -axes beneath the Cerro Galan, Cerro Blanco and Carachi Pampa volcanic centres at 100 km depth show some weak evidence for vertically orientated fast directions, which could be due to vertical asthenospheric flow around a delaminated block. Additionally, our splitting tomographic model shows that there is a significant amount of seismic anisotropy beneath the slab. The subslab mantle west of 68W shows roughly trench parallel horizontal a -axes that are probably driven by slab roll back and the relatively small coupling between the Nazca slab and the underlying mantle. In contrast, the subslab region (i.e. depths greater than 200 km) east of 68W shows a circular pattern of a -axes centred on a region with small strength of anisotropy (Cerro Galan and its eastern edge) which suggest the dominant mechanism is a combination of slab roll back and flow driven by an overlying abnormally heated slab or possibly a slab gap. There seems to be some evidence for vertical flow below the slab at depths of 200–400 km driven by the abnormally heated slab or slab gap. This cannot be resolved by the tomographic inversion due to the lack of ray crossings in the subslab mantle.
    Keywords: Seismology
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 5
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    Endothelial LSP1 Modulates Extravascular Neutrophil Chemotaxis by Regulating Nonhematopoietic Vascular PECAM-1 Expression [INNATE IMMUNITY AND INFLAMMATION] (2015)
    The American Association of Immunologists (AAI)
    Details
    Publication Date: 2015-08-22
    Description: During inflammation, leukocyte–endothelial cell interactions generate molecular signals that regulate cell functions. The Ca 2+ - and F-actin–binding leukocyte-specific protein 1 (LSP1) expressed in leukocytes and nonhematopoietic endothelial cells is pivotal in regulating microvascular permeability and leukocyte recruitment. However, cell-specific function of LSP1 during leukocyte recruitment remains elusive. Using intravital microscopy of cremasteric microvasculature of chimeric LSP1-deficient mice, we show that not neutrophil but endothelial LSP1 regulates neutrophil transendothelial migration and extravascular directionality without affecting the speed of neutrophil migration in tissue in response to CXCL2 chemokine gradient. The expression of PECAM-1–sensitive α 6 β 1 integrins on the surface of transmigrated neutrophils was blunted in mice deficient in endothelial LSP1. Functional blocking studies in vivo and in vitro elucidated that α 6 β 1 integrins orchestrated extravascular directionality but not the speed of neutrophil migration. In LSP1-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils. Similarly, LSP1-targeted small interfering RNA silencing in murine endothelial cells mitigated mRNA and protein expression of PECAM-1, but not ICAM-1 or VCAM-1. Overexpression of LSP1 in endothelial cells upregulated PECAM-1 expression. Furthermore, the expression of transcription factor GATA-2 that regulates endothelial PECAM-1 expression was blunted in LSP1-deficient or LSP1-silenced endothelial cells. The present study unravels endothelial LSP1 as a novel cell-specific regulator of integrin α 6 β 1 -dependent neutrophil extravascular chemotactic function in vivo, effective through GATA-2–dependent transcriptional regulation of endothelial PECAM-1 expression.
    Print ISSN: 0022-1767
    Electronic ISSN: 1550-6606
    Topics: Medicine
    Published by The American Association of Immunologists (AAI)
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  • 6
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    Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis (2015)
    The American Physiological Society (APS)
    Details
    Publication Date: 2015-07-02
    Description: Obesity is associated with inflammation and immune cell recruitment to adipose tissue, muscle and intima of atherosclerotic blood vessels. Obesity and hyperlipidemia are also associated with tissue insulin resistance and can compromise insulin delivery to muscle. The muscle/fat microvascular endothelium mediates insulin delivery and facilitates monocyte transmigration, yet its contribution to the consequences of hyperlipidemia is poorly understood. Using primary endothelial cells from human adipose tissue microvasculature (HAMEC), we investigated the effects of physiological levels of fatty acids on endothelial inflammation and function. Expression of cytokines and adhesion molecules was measured by RT-qPCR. Signaling pathways were evaluated by pharmacological manipulation and immunoblotting. Surface expression of adhesion molecules was determined by immunohistochemistry. THP1 monocyte interaction with HAMEC was measured by cell adhesion and migration across transwells. Insulin transcytosis was measured by total internal reflection fluorescence microscopy. Palmitate, but not palmitoleate, elevated the expression of IL-6, IL-8, TLR2 (Toll-like receptor 2), and intercellular adhesion molecule 1 (ICAM-1). HAMEC had markedly low fatty acid uptake and oxidation, and CD36 inhibition did not reverse the palmitate-induced expression of adhesion molecules, suggesting that inflammation did not arise from palmitate uptake/metabolism. Instead, inhibition of TLR4 to NF-B signaling blunted palmitate-induced ICAM-1 expression. Importantly, palmitate-induced surface expression of ICAM-1 promoted monocyte binding and transmigration. Conversely, palmitate reduced insulin transcytosis, an effect reversed by TLR4 inhibition. In summary, palmitate activates inflammatory pathways in primary microvascular endothelial cells, impairing insulin transport and increasing monocyte transmigration. This behavior may contribute in vivo to reduced tissue insulin action and enhanced tissue infiltration by immune cells.
    Print ISSN: 0193-1849
    Electronic ISSN: 1522-1555
    Topics: Medicine
    Published by The American Physiological Society (APS)
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  • 7
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    BRAVOSEIS: Geophysical investigation of rifting and volcanism in the Bransfield strait, Antarctica (2020)
    In:  EPIC3Journal of South American Earth Sciences, 104, pp. 102834, ISSN: 08959811
    Details
    Publication Date: 2020-09-15
    Description: The Bransfield Basin is a back-arc basin located in Western Antarctica between the South Shetland Islands and Antarctic Peninsula. Although the subduction of the Phoenix plate under the South Shetland block has ceased, extension continues through a combination of slab rollback and transtensional motions between the Scotia and Antarctic plates. This process has created a continental rift in the basin, interleaved with volcanic islands and seamounts, which may be near the transition from rifting to seafloor spreading. In the framework of the BRAVOSEIS project (2017–2020), we deployed a dense amphibious seismic network in the Bransfield Strait comprising 15 land stations and 24 ocean-bottom seismometers, as well as a network of 6 moored hydrophones; and acquired marine geophysics data including multibeam bathymetry, sub-bottom profiler, gravity & mag-netics, multi-channel seismics, and seismic refraction data. The experiment has collected a unique, high quality, and multifaceted geophysical data set in the Central Bransfield Basin, with a special focus on Orca and Humpback seamounts. Preliminary results confirm that the Bransfield region has slab-related intermediate depth seismicity, with earthquake characteristics suggesting distributed extension across the rift. Gravity and magnetic highs delineate a segmented rift with along-axis variations that are consistent with increased accumulated strain to the northeast. Orca volcano shows evidences of an active caldera and magma accumulation at shallow depths, while Humpback volcano has evolved past the caldera stage and is currently dominated by rifting structures. These differences suggest that volcanic evolution is influenced by the position along the rift. Although a lot of analysis remains, these results provide useful constraints on the structure and dynamics of the Bransfield rift and asso-ciated volcanoes.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 8
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    Seismic structure of the lithosphere beneath NW Namibia: Impact of the Tristan da Cunha mantle plume (2017)
    Wiley
    In:  EPIC3Geochemistry Geophysics Geosystems, Wiley, 18(1), pp. 125-141, ISSN: 1525-2027
    Details
    Publication Date: 2017-03-20
    Description: Northwestern Namibia, at the landfall of the Walvis Ridge, was affected by the Tristan da Cunha mantle plume during continental rupture between Africa and South America, as evidenced by the presence of the Etendeka continental flood basalts. Here we use data from a passive-source seismological network to investigate the upper mantle structure and to elucidate the Cretaceous mantle plume-lithosphere interaction. Receiver functions reveal an interface associated with a negative velocity contrast within the lithosphere at an average depth of 80 km. We interpret this interface as the relic of the lithosphereasthenosphere boundary (LAB) formed during the Mesozoic by interaction of the Tristan da Cunha plume head with the pre-existing lithosphere. The velocity contrast might be explained by stagnated and ‘‘frozen’’ melts beneath an intensively depleted and dehydrated peridotitic mantle. The present-day LAB is poorly visible with converted waves, indicating a gradual impedance contrast. Beneath much of the study area, converted phases of the 410 and 660 km mantle transition zone discontinuities arrive 1.5 s earlier than in the landward plume-unaffected continental interior, suggesting high velocities in the upper mantle caused by a thick lithosphere. This indicates that after lithospheric thinning during continental breakup, the lithosphere has increased in thickness during the last 132 Myr. Thermal cooling of the continental lithosphere alone cannot produce the lithospheric thickness required here. We propose that the remnant plume material, which has a higher seismic velocity than the ambient mantle due to melt depletion and dehydration, significantly contributed to the thickening of the mantle lithosphere.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 9
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    Structure of the Crust and Mantle Lithosphere underneath NW Namibia Revealed by the WALPASS Seismic Experiment (2013)
    In:  EPIC3American Geophysical Union, Fall Meeting 2013, 2013-12-09-2013-12-13AGU Fall Meeting Abstracts, pp. G2678
    Details
    Publication Date: 2014-12-11
    Description: The amphibian Walvis Ridge Passive-Source Seismic Experiment (WALPASS) have been operated for a period of two years from 2010 to 2012 in the area where the Walvis Ridge intersects the continental margin of northwestern Namibia. The deployment was intended to study the lithospheric and upper mantle structure in the ocean-continent transition area beneath the passive continental margin. The main idea is to find seismic anomalies related to the postulated hotspot track from the continent to the ocean along the Walvis Ridge that links the Etendeka continental flood-basalt province to the Tristan da Cunha hotspot in the mid Atlantic ocean. This could provide clues of the role of plume-lithosphere interaction during the continental break-up. We present here seismic structures of the crustal and mantle lithosphere in this geophysically little studied region using seismic methods including P and S receiver functions and shear wave splitting. The average crustal thickness in the continental Namibia is ~35 km with a relatively low Vp/Vs ratio of 1.7. Underneath the NE extension of the Walvis Ridge the crust is the thickest (45 km) with a high Vp/Vs ratio (〉1.80). The thick crust and high Vp/Vs ratio beneath the Walvis Ridge are consistent with high Vp derived by controlled source seismics, implying a magmatic underplating. A low velocity zone in the mantle is observed at depths of 60-120 km, possibly representing the base of the lithosphere. The P-to-S converted phases at the 410 and 660 km discontinuities arrive 2-3 s earlier, indicating higher upper mantle velocities (+5%). Seismic anisotropy in the mantle derived by the SKS splitting exhibits a pattern of the plume and plate interaction.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 10
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    Geophysical exploration of the land fall of the Tristan da Cunha plume in northern Namibia (2012)
    In:  EPIC346th Brazilian Geoligical Congress, Santos, Brazil, 2012-09-30-2012-10-05
    Details
    Publication Date: 2019-07-16
    Description: Passive continental margins offer the unique opportunity to study the processes involved in continental extension and break up and the role of hot-spot related magmatism. Several geophysical experiments (Seismics, Magnetotellurics and Seismology) were therefore carried out 2011 and 2012 in northern Namibia to image crust and upper mantle at the landfall of the Walvis Ridge. The aim of these studies is to shed light on the present-day structure of this area to understand the dynamics of the breakup of Pangaea and the processes involved. First results of the seismic part of the project show anomalous velocity structures and reflective properties in the mid- and lower crust. The lower crust (onshore) is characterized by an unusual high velocity body which might be associated with magmatic processes of the plume continent interaction. The distribution of the upper mantle wave propagation velocities shows a rather complex, very inhomogeneous pattern. Onshore magnetotelluric (MT) data were acquired at 167 sites in a ~140 km wide and ~260 km long corridor from the Atlantic Ocean through the Kaoko Mobile Belt onto the Congo Craton. The data are generally of excellent quality. A first inspection of magnetotelluric and vertical magnetic transfer functions indicates significant three-dimensional (3-D) structures in the crust and upper mantle, particularly in the Western Kaoko Zone in the vicinity of prominent shear zones. The seismological team operates a passive-source seismic experiment for two years onshore/offshore NW Namibia. The seismic network consists of 28 land-based and 12 ocean-bottom stations covering an area of 400km x 800km. Different seismic methods, such as body wave and surface wave tomography, receiver function, shear wave splitting, etc, will be used to image the seismic anomalies in the upper mantle and to map the thickness of the crust and mantle lithosphere in this ocean-continental transition area. The aim is to find the mantle deformation styles related to the plume-lithosphere interaction along the Walvis Ridge.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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