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  • 1
    Online Resource
    Online Resource
    Champaign, Ill : Project Gutenberg
    Keywords: Gordon, Adam Lindsay 1833-1870 Gordon, Adam Lindsay 1833-1870 ; Gordon, Adam Lindsay ; Frontier and pioneer life Poetry ; Australia ; Electronic books ; Frontier and pioneer life Poetry ; Electronic books ; English literature ; Australia Poetry ; Australia ; Australia Poetry ; Electronic books. ; English literature. ; English literature ; English literature ; Electronic books Poetry
    Type of Medium: Online Resource
    ISBN: 058501230X , 9780585012308
    Series Statement: EBSCOhost eBook Collection
    Language: English
    Note: Access may be limited to NetLibrary affiliated libraries , Mode of access: World Wide Web.
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  • 2
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To evaluate the clinical usefulness of Doppler analysis of the uterine artery velocity waveform in the prediction of pre-eclampsia and its associated complications of intrauterine growth retardation and perinatal death.Design Quantitative systematic review of observational diagnostic studies using online searching of the MEDLINE database coupled with scanning of the bibliographies of primary and review articles including known unpublished studies.Material Twenty-seven studies involving 12,994 subjects stratified into population subgroups at low and high risk of developing pre-eclampsia and its complications.Outcome measures The outcome measures studied were: 1. the development of pre-eclampsia; 2. intrauterine growth retardation; and 3. perinatal death. The main meta-analyses were the flow velocity waveform ratio ± diastolic notch derived by transabdominal Doppler ultrasound as the measurement parameter. The analyses were conducted using likelihood ratio as a measure of diagnostic accuracy. A likelihood ratio of 1 indicates that the test has no predictive value for the outcome. Prediction for the outcome event is considered conclusive with likelihood ratios of 〉 10 or 〈 0.1 for a positive and negative test result, respectively. Moderate prediction can be achieved with likelihood ratios of 5–10 and 0.1–0.2 whereas likelihood ratios values of 1–5 and 0.2–1 would generate only minimal prediction.Results In the low risk population a positive test result, predicted pre-eclampsia with a pooled likelihood ratio of 6.4 (95% CI 5.7–7.1), while a negative test result had a pooled likelihood ratio of 0.7 (95% CI 0.6–0.8). For intrauterine growth retardation the pooled likelihood ratio was 3.6 (95% CI 3.2–4.0) for a positive test result and 0.8 (95% CI 0.8–0.9) for a negative test result. Using perinatal death as outcome measure, the pooled likelihood ratio was 1.8 (95% CI 1.2–2.9) for a positive test result and 0.9 (95% CI 0.8–1.1) for a negative test result. In the high risk population a positive test result predicted pre-eclampsia with a pooled likelihood ratio of 2.8 (95% CI 2.3–3.4), while a negative test had a likelihood ratio of 0.8 (95% CI 0.7–0.9). For intrauterine growth retardation the pooled likelihood ratio was 2.7 (95% CI 2.1–3.4) for a positive test result and 0.7 (95% CI 0.6–0.9) for a negative result. For perinatal death the pooled likelihood ratio was 4.0 (95% CI 2.4–6.6) for a positive test result and 0.6 (95% CI 0.4–0.9) for a negative result.Conclusion Uterine artery Doppler flow velocity has limited diagnostic accuracy in predicting preeclampsia, intrauterine growth retardation and perinatal death.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 106 (1999), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To evaluate the diagnostic prediction of intrapartum umbilical artery Doppler velocimetry for adverse perinatal outcomes using systematic quantitative overview of the available literature.Design Online searching of MEDLINE database (January 1966–September 1997), scanning of bibliography of known primary and review articles, review of recent journal issues and that from personal files. Study selection, assessment of study quality and data extraction were all performed in duplicate under masked conditions.Participants 2700 women (unselected, low, high, and combined low and high obstetric risk populations) included in eight studies selected for meta-analyses.Main outcome measures Likelihood ratios (LRs) for positive and negative test results were generated for the following outcome measures: Apgar scores 〈 7 at 1 and 5 minute following delivery, small for gestational age fetus; intrapartum fetal heart rate abnormality, umbilical arterial acidosis at delivery; and caesarean section for fetal distress.Results For Apgar score 〈 7 at 1 minute following delivery, the pooled LR was 2.5 (95% CI1.7–3.7) for a positive test and 1.0 (95% CI 0.9–1.1) for a negative test result. A positive test predicted an Apgar score 〈 7 at 5 minute following delivery with a pooled LR of 1.3 (95% CI 0.4–4.1) while a negative test had a pooled LR of 1 0 (95% CI 0.8–1.2). For the prediction of a small for gestational age fetus, the pooled LR was 3.4 (95% CI 2.3–5.1) for a positive test and 0.9 (95% CI 0.8–1.0) for a negative test. The prediction for fetal heart rate abnormality during labour was similarly disappointing: the pooled LR for a positive test result was 1.4 (95% CI 0.9–1.2) whereas a negative test result generated a pooled LR of 0.9 (95% CI 0.9–1 e0). With umbilical acidosis at delivery, the pooled LR was 1.6 (95% CI 1.1–2.5) for a positive test and 1.1 (95% CI 1.0–1.2) for a negative test. The LRs for the prediction of caesarean section for fetal distress were 4.1 (95% CI 2.7–6.2) for a positive test result and 0.9 (95% CI 0.8–1.0) for a negative test result.Conclusion Intrapartum umbilical artery Doppler velocimetry is a poor predictor of adverse perinatal outcomes.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Afro-Arabian mammalian communities underwent a marked transition near the Oligocene/Miocene boundary at approximately 24 million years (Myr) ago. Although it is well documented that the endemic paenungulate taxa were replaced by migrants from the Northern Hemisphere, the timing and evolutionary ...
    Type of Medium: Electronic Resource
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  • 5
    Unknown
    Champaign, Ill : Project Gutenberg
    Keywords: English literature., lcsh
    ISBN: 0-585-01230-X
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  • 6
    Publication Date: 2015-01-24
    Description: Logging experiments with the laboratory-information management system ISPyB (Information System for Protein crystallography Beamlines) enhances the automation of small-angle X-ray scattering of biological macromolecules in solution (BioSAXS) experiments. The ISPyB interface provides immediate user-oriented online feedback and enables data cross-checking and downstream analysis. To optimize data quality and completeness, ISPyBB (ISPyB for BioSAXS) makes it simple for users to compare the results from new measurements with previous acquisitions from the same day or earlier experiments in order to maximize the ability to collect all data required in a single synchrotron visit. The graphical user interface (GUI) of ISPyBB has been designed to guide users in the preparation of an experiment. The input of sample information and the ability to outline the experimental aims in advance provides feedback on the number of measurements required, calculation of expected sample volumes and time needed to collect the data: all of this information aids the users to better prepare for their trip to the synchrotron. A prototype version of the ISPyBB database is now available at the European Synchrotron Radiation Facility (ESRF) beamline BM29 and is already greatly appreciated by academic users and industrial clients. It will soon be available at the PETRA III beamline P12 and the Diamond Light Source beamlines I22 and B21.
    Print ISSN: 0907-4449
    Electronic ISSN: 1399-0047
    Topics: Chemistry and Pharmacology , Geosciences , Physics
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