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  • 1
    Online Resource
    Online Resource
    Newark :John Wiley & Sons, Incorporated,
    Keywords: Drift. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (401 pages)
    Edition: 1st ed.
    ISBN: 9781118652589
    Series Statement: The Cryosphere Science Series
    DDC: 551.31/4
    Language: English
    Note: Cover -- Title Page -- Copyright -- Contents -- Acknowledgements -- Chapter 1 Glacigenic Diamictons - A Rationale for Study -- Chapter 2 A Brief History of Till Research and Developing Nomenclature -- Chapter 3 Till - When is it an Inappropriate Term? -- Chapter 4 Glacigenic Diamictons: A Strategy for Field Description and Analysis -- 4.1 Diamicton -- 4.2 (Glacigenic) Melange -- 4.3 Physics of Material Behaviour -- 4.4 Typical Structures -- 4.5 Clast Macrofabrics and Microfabrics -- Chapter 5 Subglacial Sedimentary Processes: Origins of Till Matrix and Terminal Grade -- Chapter 6 Subglacial Sedimentary Processes: Modern Observations on Till Evolution -- 6.1 Lodgement, Lee-Side Cavity Filling and Ploughing -- 6.2 Deformation -- 6.3 Soft-Bed Sliding (Ice Keel Ploughing), Meltwater Drainage and Ice-Bed Decoupling -- 6.4 Melt-Out -- 6.5 Glacitectonite Production, Rafting and Cannibalisation -- Chapter 7 Subglacial Sedimentary Processes: Laboratory and Modelling Experiments on Till Evolution -- Chapter 8 Measuring Strain Signatures in Glacial Deposits -- Chapter 9 The Geological Record: Products of Lodgement, Cavity Fill and the Boulder Pavement Problem -- 9.1 Introduction - Repositioning Field Studies and Experimental Reductionism -- 9.2 Lodgement -- 9.3 Clast (Boulder) Pavements -- 9.4 Lee-side Cavity Fills -- Chapter 10 The Geological Record: Deforming Bed Deposits -- Chapter 11 The Geological Record: Sliding Bed Deposits -- Chapter 12 The Geological Record: Impacts of Pressurised Water (Clastic Dykes) -- Chapter 13 The Geological Record: Melt-out Till -- Chapter 14 The Geological Record: Glacitectonite -- Chapter 15 Glacial Diamictons Unrelated to Subglacial Processes -- Chapter 16 Till Spatial Mosaics, Temporal Variability and Architecture -- Chapter 17 Concluding Remarks: The Case for a Simplified Nomenclature -- References -- Index -- EULA.
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  • 2
    Online Resource
    Online Resource
    Oxford :Taylor & Francis Group,
    Keywords: Glaciology. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (544 pages)
    Edition: 1st ed.
    ISBN: 9781444119169
    DDC: 551.315
    Language: English
    Note: Cover -- Title Page -- Copyright Page -- Table of Contents -- Preface -- List of Contributors -- Acknowledgements -- Chapter 1 Introduction to glacial landsystems -- 1.1 Landsystems -- 1.2 Glacial Landsystems -- 1.3 Aims and Scope of this Book -- Chapter 2 Ice-Marginal Terrestrial Landsystems: Active Temperate Glacier Margins -- 2.1 Introduction -- 2.2 Landform-Sediment Assemblages in Active Temperate Glacier Forelands -- 2.3 Ancient Records of Active Temperate Glacier Margins -- 2.4 Conclusion -- Chapter 3 Ice-Marginal Terrestrial Landsystems: Sub-Polar Glacier Margins of the Canadian and Greenland High Arctic -- 3.1 Introduction -- 3.2 Sub-Polar Glaciers in the Canadian and Greenland High Arctic -- 3.3 Glacial Geology and Geomorphology -- 3.4 Overlaps With Other Glacigenic Landsystems -- 3.5 Conclusion -- Chapter 4 Ice-Marginal Terrestrial Landsystems: Svalbard Polythermal Glaciers -- 4.1 Introduction and Rationale -- 4.2 Structural Glaciological Controls on Debris Entrainment and Transport -- 4.3 Geomorphology and Sedimentology of Receding Svalbard Glaciers -- 4.4 A Landsystem Model for Svalbard Glaciers -- 4.5 Application of the Model to Pleistocene Moraine Complexes -- 4.6 Conclusions -- Chapter 5 Ice-Marginal Terrestrial Landsystems: Polar-Continental Glacier Margins -- 5.1 Introduction -- 5.2 Polar Ice-Marginal Environments -- 5.3 Ice Margins in Low-Relief Landscapes -- 5.4 Ice-Contact Landforms and Sediments -- 5.5 Ice Margins in High-Relief Areas -- 5.6 Towards a Depositional Model -- Chapter 6 Ice-Marginal Terrestrial Landsystems: Southern Laurentide Ice Sheet Margin -- 6.1 Introduction -- 6.2 Physical Setting and Timing of Glaciation -- 6.3 Methods -- 6.4 Mapping and Classification of the Data -- 6.5 Landsystems of the Southern Laurentide Ice Sheet -- 6.6 Discussion -- 6.7 Conclusions. , Chapter 7 Ice-Marginal Terrestrial Landsystems: Northern Laurentide and Innuitian Ice Sheet Margins -- 7.1 Introduction -- 7.2 The Region and Its General Glacial Landscape -- 7.3 Glacial Landscape Zones -- 7.4 General Interpretation -- 7.5 Constraints on Interpretation of Glacial Landforms and Deposits in the Continuous Permafrost Zone -- 7.6 Process-Form Relationships: Towards a Landsystem Model for the Permafrost Zone -- 7.7 Discussion and Conclusion -- Chapter 8 Ice-Marginal Terrestrial Landsystems: Southern Scandinavian Ice Sheet Margin -- 8.1 Introduction -- 8.2 Glacial History -- 8.3 Regional Geology and Glacial Landsystems -- 8.4 Distribution of Glacial Landforms and Glacitectonic Styles -- 8.5 Structures Developed in Response to Subglacial Deformation -- 8.6 Structural Style of Subglacial Shear Zones -- 8.7 Ductile Shear Zone Structures -- 8.8 Brittle Shear Zone Structures -- 8.9 Glacifluvial Outwash, Ice-Marginal Valleys and Lakes -- 8.10 Glacial Landsystems of the Northern European Plains -- 8.11 Conclusions -- 8.12 Summary - Landform-Sediment Associations of the Southern Scandinavian Ice Sheet -- Chapter 9 Palaeo-Ice Stream Landsystem -- 9.1 Introduction and Rationale -- 9.2 Significance of Palaeo-Ice Streams -- 9.3 Hypotheses of Palaeo-Ice Stream Locations -- 9.4 Problems in Identifying Palaeo-Ice Streams -- 9.5 Characteristics of Existing Ice Streams -- 9.6 Geomorphological Criteria of Ice-Stream Activity -- 9.7 A Landsystem Model for Palaeo-Ice Streams -- 9.8 Application of Landsystem Models -- 9.9 Conclusion -- Chapter 10 Supraglacial Landsystems in Lowland Terrain -- 10.1 Introduction -- 10.2 Landforms -- 10.3 The Supraglacial Landsystem Model -- Chapter 11 Surging Glacier Landsystem -- 11.1 Introduction and Rationale -- 11.2 Geomorphology and Sedimentology of Contemporary Surging Glaciers. , 11.3 Summary of the Landsystems Model for Surging Glaciers -- 11.4 Application of the Surging Glacier Landsystem -- 11.5 Conclusion -- Chapter 12 Subaquatic Landsystems: Continental Margins -- 12.1 The Continental Shelf System -- 12.2 The Continental Slope and Adjoining Deep-Sea System -- 12.3 Summary -- Chapter 13 Subaquatic Landsystems: Fjords -- 13.1 Introduction -- 13.2 Sedimentary Processes and External Forces -- 13.3 Geomorphology and Depositional Systems -- 13.4 Modelling Fjord Landsystems -- 13.5 Conclusion -- Chapter 14 Subaquatic Landsystems: Large Proglacial Lakes -- 14.1 Introduction -- 14.2 Controls on Formation and Extent of Proglacial Lakes -- 14.3 The Sedimentary Record of Large Proglacial Lakes -- 14.4 Summary of Development of Large Proglacial Lakes -- Chapter 15 Glaciated Valley Landsystems -- 15.1 Introduction -- 15.2 Sediment Sources -- 15.3 Sediment Transport Pathways -- 15.4 Dynamics of Debris-Covered Glaciers -- 15.5 Landsystems of Glacial Deposition -- 15.6 Rock Glaciers -- 15.7 Landsystems of Proglacial Deposition -- 15.8 Proglacial Aeolian Landsystems -- 15.9 Ice- and Moraine-Dammed Lakes -- 15.10 Glaciated Valley Landsystems: Synthesis -- 15.11 Changes in Landsystem Distribution Over Space and Time -- 15.12 Conclusions -- Chapter 16 Plateau Icefield Landsystems -- 16.1 Introduction and rationale -- 16.2 Area Altitude Relationship for Plateau Icefields -- 16.3 Contemporary Plateau Icefields -- 16.4 Dynamics of Plateau Icefields -- 16.5 The Plateau Icefield Landsystem -- 16.6 Impact of Plateau Ice on Reconstructed Equilibrium Line Altitudes -- 16.7 Discussion -- 16.8 Conclusions -- Chapter 17 Paraglacial Landsystems -- 17.1 Introduction -- 17.2 Paraglacial Landsystems -- 17.3 Paraglacial Rock Slope Landsystems -- 17.4 Paraglacial Drift-Mantled Slope Landsystems -- 17.5 Paraglacial Modification of Glacier Forelands. , 17.6 Paraglacial Alluvial Landsystems -- 17.7 Paraglacial Sedimentation in Lakes -- 17.8 Paraglacial Coastal Landsystems -- 17.9 Paraglacial Landsystems and Postglacial Landscape Change -- 17.10 Implications for Glacial Landsystems -- References -- Index.
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  • 3
    Online Resource
    Online Resource
    Oxford :Taylor & Francis Group,
    Keywords: Glaciers. ; Electronic books.
    Description / Table of Contents: A new edition of the classic textbook for all students of glaciation.
    Type of Medium: Online Resource
    Pages: 1 online resource (817 pages)
    Edition: 2nd ed.
    ISBN: 9781444128390
    DDC: 551.31
    Language: English
    Note: Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface to the First Edition -- Preface to the Second Edition -- Acknowledgements -- Part One Glaciers -- 1 Introduction -- 1.1 Glacier systems -- 1.1.1 Mass balance -- 1.1.2 Meltwater -- 1.1.3 Glacier motion -- 1.1.4 Glaciers and sea-level change -- 1.1.5 Erosion and debris transport -- 1.1.6 Glacial sediments, landforms and landscapes -- 1.2 Glacier morphology -- 1.2.1 Ice sheets and ice caps -- 1.2.2 Glaciers constrained by topography -- 1.2.3 Ice shelves -- 1.3 Present distribution of glaciers -- 1.3.1 Influence of latitude and altitude -- 1.3.2 Influence of aspect, relief and distance from a moisture source -- 1.4 Past distribution of glaciers -- 1.4.1 'Icehouse' and 'greenhouse' worlds -- 1.4.2 Cenozoic glaciation -- 2 Snow, Ice and Climate -- 2.1 Introduction -- 2.2 Surface energy balance -- 2.2.1 Changes of state and temperature -- 2.2.2 Shortwave radiation -- 2.2.3 Longwave radiation -- 2.2.4 Sensible and latent heat: turbulent fluxes -- 2.2.5 Energy supplied by rain -- 2.2.6 Why is glacier ice blue? -- 2.3 Ice temperature -- 2.3.1 The melting point of ice -- 2.3.2 Controls on ice temperature -- 2.3.3 Thermal structure of glaciers and ice sheets -- 2.4 Processes of accumulation and ablation -- 2.4.1 Snow and ice accumulation -- 2.4.2 Transformation of snow to ice -- 2.4.3 Melting of snow and ice -- 2.4.4 Sublimation and evaporation -- 2.4.5 The influence of debris cover -- 2.5 Mass balance -- 2.5.1 Definitions -- 2.5.2 Measurement of mass balance -- 2.5.3 Annual mass balance cycles -- 2.5.4 Mass balance gradients -- 2.5.5 The equilibrium line -- 2.5.6 Glaciation levels or glaciation thresholds -- 2.5.7 Glacier sensitivity to climate change -- 2.6 Glacier-climate interactions -- 2.6.1 Effects of glaciers and ice sheets on the atmosphere -- 2.7 Ice cores. , 2.7.1 Ice coring programmes -- 2.7.2 Stable isotopes -- 2.7.3 Ancient atmospheres: the gas content of glacier ice -- 2.7.4 Solutes and particulates -- 3 Glacier Hydrology -- 3.1 Introduction -- 3.2 Basic concepts -- 3.2.1 Water sources and routing -- 3.2.2 Hydraulic potential -- 3.2.3 Resistance to flow -- 3.2.4 Channel wall processes: melting, freezing and ice deformation -- 3.3 Supraglacial and englacial drainage -- 3.3.1 Supraglacial water storage and drainage -- 3.3.2 Englacial drainage -- 3.4 Subglacial drainage -- 3.4.1 Subglacial channels -- 3.4.2 Water films -- 3.4.3 Linked cavity systems -- 3.4.4 Groundwater flow -- 3.4.5 Water at the ice-sediment interface -- 3.5 Glacial hydrological systems -- 3.5.1 Temperate glaciers -- 3.5.2 Polythermal glaciers -- 3.5.3 Modelling glacial hydrological systems -- 3.6 Proglacial runoff -- 3.6.1 Seasonal and shorter-term cycles -- 3.6.2 Runoff and climate change -- 3.7 Glacial lakes and outburst floods -- 3.7.1 Introduction -- 3.7.2 Moraine-dammed lakes -- 3.7.3 Ice-dammed lakes -- 3.7.4 Icelandic subglacial lakes -- 3.7.5 Estimating GLOF magnitudes -- 3.8 Life in glaciers -- 3.8.1 Supraglacial ecosystems -- 3.8.2 Subglacial ecosystems -- 3.9 Glacier hydrochemistry -- 3.9.1 Overview -- 3.9.2 Snow chemistry -- 3.9.3 Chemical weathering processes -- 3.9.4 Subglacial chemical weathering -- 3.9.5 Proglacial environments -- 3.9.6 Rates of chemical erosion -- 4 Processes of Glacier Motion -- 4.1 Introduction -- 4.2 Stress and strain -- 4.2.1 Stress -- 4.2.2 Strain -- 4.2.3 Rheology: stress-strain relationships -- 4.2.4 Force balance in glaciers -- 4.3 Deformation of ice -- 4.3.1 Glen's Flow Law -- 4.3.2 Crystal fabric, impurities and water content -- 4.3.3 Ice creep velocities -- 4.4 Sliding -- 4.4.1 Frozen beds -- 4.4.2 Sliding of wet-based ice -- 4.4.3 Glacier-bed friction -- 4.4.4 The role of water. , 4.5 Deformable beds -- 4.5.1 The Boulton-Hindmarsh model -- 4.5.2 Laboratory testing of subglacial tills -- 4.5.3 Direct observations of deformable glacier beds -- 4.5.4 Rheology of subglacial till -- 4.6 Rates of basal motion -- 4.6.1 'Sliding laws' -- 4.6.2 Local and non-local controls on ice velocity -- 4.7 Crevasses and other structures: strain made visible -- 4.7.1 Crevasses -- 4.7.2 Crevasse patterns -- 4.7.3 Layering, foliation and related structures -- 5 Glacier Dynamics -- 5.1 Introduction -- 5.2 Understanding glacier dynamics -- 5.2.1 Balance velocities -- 5.2.2 Deviations from the balance velocity -- 5.2.3 Changes in ice thickness: continuity -- 5.2.4 Thermodynamics -- 5.3 Glacier models -- 5.3.1 Overview -- 5.3.2 Equilibrium glacier profiles -- 5.3.3 Time-evolving glacier models -- 5.4 Dynamics of valley glaciers -- 5.4.1 Intra-annual velocity variations -- 5.4.2 Multi-annual variations -- 5.5 Calving glaciers -- 5.5.1 Flow of calving glaciers -- 5.5.2 Calving processes -- 5.5.3 'Calving laws' -- 5.5.4 Advance and retreat of calving glaciers -- 5.6 Ice shelves -- 5.6.1 Mass balance of ice shelves -- 5.6.2 Flow of ice shelves -- 5.6.3 Ice shelf break-up -- 5.7 Glacier surges -- 5.7.1 Overview -- 5.7.2 Distribution of surging glaciers -- 5.7.3 Temperate glacier surges -- 5.7.4 Polythermal surging glaciers -- 5.7.5 Surge mechanisms -- 6 The Greenland and Antarctic Ice Sheets -- 6.1 Introduction -- 6.2 The Greenland Ice Sheet -- 6.2.1 Overview -- 6.2.2 Climate and surface mass balance -- 6.2.3 Ice sheet flow -- 6.2.4 Ice streams and outlet glaciers -- 6.3 The Antarctic Ice Sheet -- 6.3.1 Overview -- 6.3.2 Climate and mass balance -- 6.3.3 Flow of inland ice -- 6.3.4 Ice streams -- 6.3.5 Hydrology and subglacial lakes -- 6.3.6 Ice stream stagnation and reactivation -- 6.3.7 Stability of the West Antarctic Ice Sheet. , 7 Glaciers and Sea-Level Change -- 7.1 Introduction -- 7.2 Causes of sea-level change -- 7.2.1 Overview -- 7.2.2 Glacio-eustasy and global ice volume -- 7.2.3 Glacio-isostasy and ice sheet loading -- 7.3 Sea-level change over glacial-interglacial cycles -- 7.3.1 Ice sheet fluctuations and eustatic sea-level change -- 7.3.2 Sea-level histories in glaciated regions -- 7.4 Glaciers and recent sea-level change -- 7.4.1 Recorded sea-level change -- 7.4.2 Global glacier mass balance -- 7.5 Future sea-level change -- 7.5.1 IPCC climate and sea-level projections -- 7.5.2 Predicting the glacial contribution to sea-level change -- Part Two Glaciation -- 8 Erosional Processes, Forms and Landscapes -- 8.1 Introduction -- 8.2 Subglacial erosion -- 8.2.1 Rock fracture: general principles -- 8.2.2 Abrasion -- 8.2.3 Quarrying -- 8.2.4 Erosion beneath cold ice -- 8.2.5 Erosion of soft beds -- 8.3 Small-scale erosional forms -- 8.3.1 Striae and polished surfaces -- 8.3.2 Rat tails -- 8.3.3 Chattermarks, gouges and fractures -- 8.3.4 P-forms -- 8.4 Intermediate-scale erosional forms -- 8.4.1 Roches moutonnées -- 8.4.2 Whalebacks and rock drumlins -- 8.4.3 Crag and tails -- 8.4.4 Channels -- 8.5 Large-scale erosional landforms -- 8.5.1 Rock basins and overdeepenings -- 8.5.2 Basins and overdeepenings in soft sediments -- 8.5.3 Troughs and fjords -- 8.5.4 Cirques -- 8.5.5 Strandflats -- 8.6 Landscapes of glacial erosion -- 8.6.1 Areal scouring -- 8.6.2 Selective linear erosion -- 8.6.3 Landscapes of little or no glacial erosion -- 8.6.4 Alpine landscapes -- 8.6.5 Cirque landscapes -- 8.6.6 Continent-scale patterns of erosion -- 9 Debris Entrainment and Transport -- 9.1 Introduction -- 9.2 Approaches to the study of glacial sediments -- 9.2.1 The glacial debris cascade -- 9.2.2 Spatial hierarchies of sediments and landforms -- 9.3 Glacial debris entrainment. , 9.3.1 Supraglacial debris entrainment -- 9.3.2 Incorporation of debris into basal ice -- 9.4 Debris transport and release -- 9.4.1 Subglacial transport -- 9.4.2 High-level debris transport -- 9.4.3 Glacifluvial transport -- 9.5 Effects of transport on debris -- 9.5.1 Granulometry -- 9.5.2 Clast morphology -- 9.5.3 Particle micromorphology -- 10 Glacigenic Sediments and Depositional Processes -- 10.1 Introduction -- 10.2 Sediment description and classification -- 10.2.1 Sediment description -- 10.2.2 Deformation structures -- 10.2.3 Primary and secondary deposits -- 10.3 Primary glacigenic deposits (till) -- 10.3.1 Overview -- 10.3.2 Processes of subglacial till formation -- 10.3.3 Glacitectonite -- 10.3.4 Subglacial traction till -- 10.4 Glacifluvial deposits -- 10.4.1 Terminology and classification of glacifluvial sediments -- 10.4.2 Plane bed deposits -- 10.4.3 Ripple cross-laminated facies -- 10.4.4 Dunes -- 10.4.5 Antidunes -- 10.4.6 Scour and minor channel fills -- 10.4.7 Gravel sheets -- 10.4.8 Silt and mud drapes -- 10.4.9 Hyperconcentrated flow deposits -- 10.5 Gravitational mass movement deposits and syn-sedimentary deformation structures -- 10.5.1 Overview -- 10.5.2 Fall deposits -- 10.5.3 Slide and slump deposits -- 10.5.4 Debris (sediment-gravity) flow deposits -- 10.5.5 Turbidites -- 10.5.6 Clastic dykes and hydrofracture fills -- 10.6 Glacimarine and glacilacustrine deposits -- 10.6.1 Water body characteristics and sediment influx -- 10.6.2 Depositional processes -- 10.6.3 Varves and other glacilacustrine overflow/interflow deposits -- 10.6.4 Laminated glacimarine sediments -- 10.6.5 Ice-rafted debris and undermelt deposits -- 10.6.6 Iceberg grounding structures and sediments -- 10.6.7 Fossiliferous deposits and biogenic oozes -- 10.7 Winnowing structures (lags, coquinas and boulder pavements) -- 11 Sediment-Landform Associations. , 11.1 Introduction.
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  • 4
    Keywords: Geology and Palaeontology ; glacial landforms ; Aufsatzsammlung ; Glazialmorphologie ; Glazialmorphologie
    Type of Medium: Book
    Pages: XVI, 526 S. , Ill., graph. Darst.
    ISBN: 0471940437
    Series Statement: International Geomorphology Series
    DDC: 551.41
    RVK:
    RVK:
    RVK:
    Language: English
    Note: Literaturverz. S. [475] - 516
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  • 5
    Book
    Book
    London : Arnold
    Keywords: Glaciers ; Glaciers ; Glaciology ; Glaciers ; Glacial landforms ; Glaciology ; Vergletscherung ; Gletscher ; Glaziologie
    Type of Medium: Book
    Pages: VII, 734 S , Ill., graph. Darst., Kt , 28 cm
    ISBN: 0340653035 , 0340584319 , 0470236515 , 0470236507
    DDC: 551.31
    RVK:
    RVK:
    RVK:
    Language: English
    Note: Literaturverz. S. [631] - 716 , Literaturverz. S. [631] - 716
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  • 6
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: SummaryStrains of Pseudomonas aeruginosa initially isolated from patients with cystic fibrosis (CF) often express a smooth lipopolysaccharide (LPS) containing many long O side-chain antigens, but once a chronic infection is established, strains recovered from these patients express little or no LPS O antigen. The genetic basis for this loss of O antigen expression by P. aeruginosa CF isolates is unknown. We report here that 20 CF isoiates of P. aeruginosa, 13 of which are LPS-rough, were each capable of expressing serogroup 011 antigen when provided with the rfb iocus from P. aeruginosa serogroup 011 strain PA103 on the recombinant plasmid pLPS2. Eight of the thirteen LPS-rough isolates co-expressed another, presumably endogenous, O antigen when they contained pLPS2. Different subcloned regions of pLPS2 complemented distinct strains to restore endogenous O antigen expression. These data suggest that the loss of O antigen expression by P. aeruginosa CF isolates results from alterations specific to the rfb region, and is not due to mutations involving other loci or ancillary LPS genes.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 57 (2001), S. 987-988 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The reaction of ethoxycarbonylpyrrole-2-thiocarboxamide with sodium hydroxide affords the known title compound, C5H6N2S, whose structure shows a three-dimensional hydrogen-bonded lattice.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Identification of the genes underlying complex phenotypes and the definition of the evolutionary forces that have shaped eukaryotic genomes are among the current challenges in molecular genetics. Variation in gene copy number is increasingly recognized as a source of inter-individual ...
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 57 (2001), S. m509-m510 
    ISSN: 1600-5368
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The ions of the title compound, (C8H20N)[NiCl3(C18H15P)], both lie on the threefold rotation axes along the body diagonal vectors of a cubic unit cell in the space group Pb\overline 3 (equivalent to Pa\overline 3, No. 205, with h and k indices interchanged). The Ni atom within the anion is tetrahedrally coordinated to three symmetry-related Cl atoms and the P atom. The cation is disordered.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 213 (2002), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Invasion of epithelial cells represents a potential pathogenic mechanism for Pseudomonas aeruginosa. We explored the role of mitogen-activated protein kinase kinases (MEK 1/2) and the extracellular signal-regulated kinases (ERK 1/2) in P. aeruginosa invasion. Treatment of corneal epithelial cells with MEK inhibitors, PD98059 (20 μM) or UO126 (100 μM), reduced P. aeruginosa invasion by ∼60% without affecting bacterial association with the cells (P=0.0001). UO124, a negative control for UO126, had no effect on bacterial internalization. Infection of cells with an internalization-defective flhA mutant of P. aeruginosa was associated with less ERK 1/2 tyrosine phosphorylation than infection with wild-type invasive P. aeruginosa. An ERK-2 inhibitor, 5-iodotubercidin (20 μM), reduced P. aeruginosa invasion by ∼40% (P=0.035). Together, these data suggest that P. aeruginosa internalization by epithelial cells involves a pathway(s) that includes MEK and ERK signaling proteins.
    Type of Medium: Electronic Resource
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