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  • 1
    Keywords: Forschungsbericht
    Type of Medium: Online Resource
    Pages: Online-Ressource (39 S., 13 MB) , Ill., graph. Darst
    Language: German , English
    Note: Förderkennzeichen BMBF 03G0564C. - Verbund-Nr. 01018235. - Dt. Titel: Instrumente zur Quantifizierung des Energie- und Fluidflusses in Gashydrat führenden Sedimenten. - Text teilw. dt., teilw. engl. - Literaturverz. Bl. 21 , Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden , Auch als gedr. Ausg. vorh , Systemvoraussetzungen: Acrobat reader.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Molecular and cellular biochemistry 120 (1993), S. 81-85 
    ISSN: 1573-4919
    Keywords: neutrophils ; nifedipine ; superoxide ; chemotaxis ; phagocytosis ; NADPH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Administration of nifedipine to mice over a period of six months caused a significant (p〈0.05) decrease in neutrophilic functions viz superoxide generation, coupled to NADPH oxidase activity as well as NADPH production by HMP shunt. Properties like chemotaxis and phagocytosis showed a similar decrease. From this study, it is seen that nifedipine causes neutrophil functional abrogation which is therefore an apparent concern for the prolonged usage of the drug. However, relevance of the mouse model to clinical situation needs further investigation.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Molecular and cellular biochemistry 160-161 (1996), S. 283-288 
    ISSN: 1573-4919
    Keywords: oxidative stress ; superoxide dismutase ; glutathione peroxidase ; catalase ; lipid peroxidation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Earlier we reported that probucol treatment subsequent to the induction of diabetes can prevent diabetes-associated changes in myocardial antioxidants as well as function at 8 weeks. In this study, we examined the efficacy of probucol in the reversal of diabetes induced myocardial changes. Rats were made diabetic with a single injection of streptozotocin (65 mg/kg, i.v.). After 4 weeks of induction of diabetes, a group of animals was treated on alternate days with probucol (10 mg/kg i.p.), a known lipid lowering agent with antioxidant properties. At 8 weeks, there was a significant drop in the left ventricle (LVSP) and aortic systolic pressures (ASP) in the diabetic group. Hearts from these animals showed an increase in the thiobarbituric acid reacting substances (TBARS), indicating increased lipid peroxidation. This was accompanied by a decrease in the myocardial antioxidant enzymes activities, superoxide dismutase (SOD) and glutathione peroxidase (GSHPx). Myocardial catalase activity in the diabetic group was higher. In the diabetic + probucol group both LVSP and ASP showed significant recovery. This was also accompanied by an improvement in SOD and GSHPx activities and there was further increase in the catalase activity. Levels of the TBARS were decreased in this group. These data provide evidence that diabetic cardiomyopathy is associated with an antioxidant deficit which can be reversed with probucol treatment. Improved cardiac function with probucol may be due to the recovery of antioxidants in the heart.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Basic research in cardiology 87 (1992), S. 512-518 
    ISSN: 1435-1803
    Keywords: Adrenergic changes cardiomyopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Natural history of myocardial dysfunction due to chronic contractile deficit consists of physiological and pathophysiological adaptations culminating in congestive heart failure. Among the mechanisms considered is the combination of compensatory as well as the harmful overcompensatory role of the adrenergic system during the genesis of a congestive heart failure “spiral” due to the chronic treatment with adriamycin. Refractoriness of this spiral to various inotropic agents may involve reduced sympathetic support of the myocardium, structural loss of contractile elements and abnormalities of the Ca2+ metabolism.
    Type of Medium: Electronic Resource
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  • 5
    Publication Date: 2020-02-06
    Description: On the basis of heat-flow measurements, seismic mapping, and sediment pore-water analysis, we demonstrate widespread and efficient ventilation of the 18–22 Ma oceanic crust of the northeast equatorial Pacific Ocean. Recharge and discharge appear to be associated with basement outcrops, including seamounts and north-south–trending faults, along which sediment cover thins out and volcanic rocks are exposed. Low-temperature hydrothermal circulation through the volcanic crust leads to the reduction of heat flow through overlying sediments, with measured heat-flow values that are well below those expected from conductive cooling curves for lithosphere of this age. Typically, dissolved pore-water oxygen decreases from the sediment surface downward, reaching minimum values at mid-depth and rising again in the lower part of the cores investigated, clearly indicating oxygen-rich seawater circulation through the oceanic crust underneath the sediments. If the residence time of the circulating fluids in the upper crust is short or the fluid flux is large, oxic conditions may be preserved, and oxygen can diffuse upwards into the sediments. This process, leading to widespread oxic conditions in the near-basement sediments, may cause the oxidation of residual reduced material stored in the deeper sediments, resulting in downward fluxes of the reaction products into the basement and from there back into the oceans. Considering the widespread existence of this type of off-axis ventilation, the net effect of the resulting return flow of reaction products on biogeochemical cycles and element fluxes (e.g., carbon and nitrogen) may be very large.
    Type: Article , PeerReviewed
    Format: text
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  • 6
    Publication Date: 2019-10-24
    Description: We report on newly discovered mud volcanoes located at ∼4500 m water depth ∼90 km west of the deformation front of the accretionary wedge of the Gulf of Cadiz, and thus outside of their typical geotectonic environment. Seismic data suggest that fluid flow is mediated by a 〉400-km-long strike-slip fault marking the transcurrent plate boundary between Africa and Eurasia. Geochemical data (Cl, B, Sr, 87Sr/86Sr, δ18O, δD) reveal that fluids originate in oceanic crust older than 140 Ma. On their rise to the surface, these fluids receive strong geochemical signals from recrystallization of Upper Jurassic carbonates and clay-mineral dehydration in younger terrigeneous units. At present, reports of mud volcanoes in similar deep-sea settings are rare, but given that the large area of transform-type plate boundaries has been barely investigated, such pathways of fluid discharge may provide an important, yet unappreciated link between the deeply buried oceanic crust and the deep ocean.
    Type: Article , PeerReviewed
    Format: text
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  • 7
    Publication Date: 2020-04-22
    Description: The main objective of cruise M146 was the discovery and documentation of inferred fluid venting sites at Henry Seamount, an extinct 126 Ma old volcano located 40 km to the southeast of El Hierro island. Evidence of recent fluid discharge at this seamount was provided by rock and shell samples from a reconnaissance dredging campaign during METEOR cruise M66/1. Such discharge could reflect hydrothermal circulation of seawater through the old oceanic crust, a globally important process. This type of circulation requires basement outcrops through the impermeable sediment cover, which can be provided by seamounts and island flanks. To achieve the goals, we carried out a hydroacoustic survey of Henry Seamount using the ship's multibeam echosounder and PARASOUND system, and mapped an area of 31 km² in detail during seven AUV dives. About 600 km of reflection seismic profiles were shot across the seamount and its vicinity to reveal sub-bottom structures and basement outcrops. As a potential tracer for fluid discharge or recharge sites, the heat flow in the area was determined by more than 50 measurements along four profiles using a heat flow probe. During seven TV sled surveys we explored the seafloor on the top and flanks of Henry Seamount, and logged temperature, turbidity and geochemical potential of the bottom water. Five gravity cores and 13 grabs provided samples of sediment, shells and other biota, and revealed conspicuous basaltic ash and lapilli layers. Our data show that surprisingly large areas of the seamount are covered with Abyssogena clam shells, testifying widespread past fluid discharge, even though this is not reflected in the heat flow data. Oxydation-reduction potential (ORP) anomalies in the bottom water indicate that in some areas fluids are still discharging.
    Type: Report , NonPeerReviewed
    Format: text
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  • 8
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    Royal Astronomical Society, DGG
    In:  Geophysical Journal International, 152 (3). pp. 688-698.
    Publication Date: 2015-01-28
    Description: New geophysical data have become available from shipborne and satellite measurements allowing a re-evaluation of the largely unknown junction of the Arctic spreading centre and the northeastern Siberian continental margin where the transpolar mid-ocean Gakkel Ridge abuts against the continental slope of the Laptev Sea. Based on multichannel seismic reflection and gravity data, this sediment-covered spreading axis can be traced to the continental rise where it is cut-off by a transcurrent fault. Further continuation of the extensional axis into the continental slope can be attributed to two asymmetric grabens, which terminate against the prominent Khatanga–Lomonosov Fracture. Remnants of hydrothermal fauna and high heat-flow values of approximately 100 mW m−2 documented around these grabens in the up-slope area are typical for an oceanic spreading axis. Thus we consider these grabens to be morphotectonic termination of the global Atlantic–Arctic spreading system with plate motions shifting to the Khatanga–Lomonosov Fracture. The high heat flow and the distribution of earthquake epicentres allow us to assume that the present-day divergent plate tectonic boundary passes from the Gakkel Ridge to the eastern part of Laptev Sea with an offset of initial rifting along the Bel'kov–Svyatoi Nos Rift to the projected prolongation of the buried spreading axis by 140–150 km.
    Type: Article , PeerReviewed
    Format: text
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  • 9
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    GeoForschungsZentrum
    In:  [Talk] In: Sonderkolloquium "Geotechnologien", GeoForschungsZentrum Potsdam, 09.-10.06.2005, Potsdam . Continental margins - earth's focal points of usage and hazard potential ; pp. 100-105 .
    Publication Date: 2012-07-06
    Type: Conference or Workshop Item , NonPeerReviewed
    Format: text
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  • 10
    Publication Date: 2021-01-20
    Description: R/V Meteor cruise M162 was conducted as a systematic continuation of ongoing work dedicated to understand if and howfluid flow through crust and sedimentscontinues along transform-type plate boundaries and fracture zones away from mid-ocean ridges and continental margins. Central target was the Gloria Fault in the central Northeast Atlantic. Previous findings along the eastern continuation of the Gloria Fault revealed fault-controlled fluid advection and mud volcanism along strike-slip faults in the Horseshoe Abyssal Plain and the Gulf of Cadiz, where fluid geochemistry revealed the admixture of fluids from deeply buried oceanic crust and oldest sediments on top of it. TheGloria Fault itselfis an old, reactivated, and seismically active oceanic fracture zone. During M162 a systematic survey along the main trace of the Gloria Fault between the Azores Plateau and the Madeira-Tore Rise was carried out, including sub-bottom profiler surveys, heat flow transects, gravity corer sampling, as well as video-guided CTD and multicorer deployments. In accordance to recently recorded seismic activity along the fault, there isevidence for tectonic motion both in sub-bottom profiler records and sediment cores. Heat flow measurements revealed values significantly elevated above the background in many places, predominantly along the main fault trace and other active faults.Ina number of placesfluid geochemistry revealed enhanced diagenetic processes in the sediments, implying the potential relation to upward-directed fluid flow. In summary, cruise M162revealed the first complementary data set on heat flow and fluid geochemistry along an oceanic fault zone, which will further our understanding on themes like the alteration of oceanic lithosphere and crust-ocean element exchange.
    Type: Report , NonPeerReviewed
    Format: text
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