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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of human genetics 32 (1987), S. 83-89 
    ISSN: 1435-232X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The genetic polymorphism of serum group-specific component (Gc) was studied in two Chinese (Han) populations using isoelectric focusing followed by immunofixation. Six common and seven rare variant phenotypes were observed among 155 samples from Beijing and 256 samples from Guangzhou. The frequencies for the common alleles,Gc * 1F,Gc * 1S, andGc * 2, were 0.4774, 0.2000, and 0.3065, respectively, for Beijing, and 0.4316, 0.2891, and 0.2734, respectively, for Guangzhou. Only the frequency ofGc * 1S showed a statistically significant difference between the two localities. The rare Gc variants observed were: Gc 1A3, Gc 1A8, Gc 1C18 and Gc 2A4. Furthermore, two new rare Gc variants were detected and named Gc 1C50 and Gc 2A19.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Journal of human genetics 31 (1986), S. 263-271 
    ISSN: 1435-232X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Genetic polymorphisms of the complement components C6 and C7 in two Chinese populations (Beijing and Guangzhou) were investigated, using isoelectric focusing and immunoblotting technique. Three common and four rare allotypes of C6 were observed, and one of the rare allotypes was considered to be a new variant. Ten different patterns of C7 observed were classified into three homozygous and seven heterozygous phenotypes, indicating occurrence of four common and a new variant alleles. The new variants of C6 and C7 detected were designated as C6 B21 and C7 6, respectively. There was no statistically significant difference for C6 and C7 allele frequencies between the Beijing and the Guangzhou populations except forC7 *4. TheC7 *4 frequency was shown to be significantly higher in Beijing than in Guangzhou. No significant positive association between C6 and C7 alleles was found.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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