ISSN:
1435-232X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The genetic polymorphism of serum group-specific component (Gc) was studied in two Chinese (Han) populations using isoelectric focusing followed by immunofixation. Six common and seven rare variant phenotypes were observed among 155 samples from Beijing and 256 samples from Guangzhou. The frequencies for the common alleles,Gc * 1F,Gc * 1S, andGc * 2, were 0.4774, 0.2000, and 0.3065, respectively, for Beijing, and 0.4316, 0.2891, and 0.2734, respectively, for Guangzhou. Only the frequency ofGc * 1S showed a statistically significant difference between the two localities. The rare Gc variants observed were: Gc 1A3, Gc 1A8, Gc 1C18 and Gc 2A4. Furthermore, two new rare Gc variants were detected and named Gc 1C50 and Gc 2A19.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01893161
