ISSN:
1435-232X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Genetic polymorphisms of the complement components C6 and C7 in two Chinese populations (Beijing and Guangzhou) were investigated, using isoelectric focusing and immunoblotting technique. Three common and four rare allotypes of C6 were observed, and one of the rare allotypes was considered to be a new variant. Ten different patterns of C7 observed were classified into three homozygous and seven heterozygous phenotypes, indicating occurrence of four common and a new variant alleles. The new variants of C6 and C7 detected were designated as C6 B21 and C7 6, respectively. There was no statistically significant difference for C6 and C7 allele frequencies between the Beijing and the Guangzhou populations except forC7 *4. TheC7 *4 frequency was shown to be significantly higher in Beijing than in Guangzhou. No significant positive association between C6 and C7 alleles was found.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01870757
