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  • 1
    Publication Date: 2016-02-06
    Description: We prove a variety of results describing the diagonals of tuples of commuting hermitian operators in type II $_1$ factors. These results, motivated by work of Arveson and Kadison, are generalizations of the classical Schur–Horn theorem to the infinite-dimensional, multivariable setting. Our description of these possible diagonals uses a natural generalization of the classical notion of majorization. In the special case when both the given tuple and the desired diagonal have finite joint spectrum, our results are complete. When the tuples do not have finite joint spectrum, we are able to prove strong approximate results. Unlike the single variable case, the multivariable case presents several surprises and we point out obstructions to extending our complete description in the finite spectrum case to the general case. We also discuss the problem of characterizing diagonals of commuting tuples in ${\mathcal B}({\mathcal H})$ and give approximate characterizations in this case as well.
    Print ISSN: 0024-6115
    Electronic ISSN: 1460-244X
    Topics: Mathematics
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  • 2
    Publication Date: 2016-10-26
    Description: Epigenetic memory, in particular DNA methylation, is established during development in differentiating cells and must be erased to create naïve (induced) pluripotent stem cells. The ten-eleven translocation (TET) enzymes can catalyze the oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and further oxidized derivatives, thereby actively removing this memory. Nevertheless, the...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 3
    Publication Date: 2018-12-04
    Description: Cells that contain an abnormal number of chromosomes are called aneuploid. High rates of aneuploidy in cancer are correlated with an increased frequency of chromosome missegregation, termed chromosomal instability (CIN). Both high levels of aneuploidy and CIN are associated with cancers that are resistant to treatment. Although aneuploidy and CIN are typically detrimental to cell growth, they can aid in adaptation to selective pressures. Here, we induced extremely high rates of chromosome missegregation in yeast to determine how cells adapt to CIN over time. We found that adaptation to CIN occurs initially through many different individual chromosomal aneuploidies. Interestingly, the adapted yeast strains acquire complex karyotypes with specific subsets of the beneficial aneuploid chromosomes. These complex aneuploidy patterns are governed by synthetic genetic interactions between individual chromosomal abnormalities, which we refer to as chromosome copy number interactions (CCNIs). Given enough time, distinct karyotypic patterns in separate yeast populations converge on a refined complex aneuploid state. Surprisingly, some chromosomal aneuploidies that provided an advantage early on in adaptation are eventually lost due to negative CCNIs with even more beneficial aneuploid chromosome combinations. Together, our results show how cells adapt by obtaining specific complex aneuploid karyotypes in the presence of CIN.
    Print ISSN: 0890-9369
    Topics: Biology
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  • 4
    Publication Date: 2021-09-21
    Description: We present an analysis of annual and seasonal mean characteristics of the Indian Ocean circulation and water masses from 16 global ocean-sea-ice model simulations that follow the Coordinated Ocean-ice Reference Experiments (CORE) interannual protocol (CORE-II). All simulations show a similar large-scale tropical current system, but with differences in the Equatorial Undercurrent. Most CORE-II models simulate the structure of the Cross Equatorial Cell (CEC) in the Indian Ocean. We uncover a previously unidentified secondary pathway of northward cross-equatorial transport along 75 °E, thus complementing the pathway near the Somali Coast. This secondary pathway is most prominent in the models which represent topography realistically, thus suggesting a need for realistic bathymetry in climate models. When probing the water mass structure in the upper ocean, we find that the salinity profiles are closer to observations in geopotential (level) models than in isopycnal models. More generally, we find that biases are model dependent, thus suggesting a grouping into model lineage, formulation of the surface boundary, vertical coordinate and surface salinity restoring. Refinement in model horizontal resolution (one degree versus ¼ degree) does not significantly improve simulations, though there are some marginal improvements in the salinity and barrier layer results. The results in turn suggest that a focus on improving physical parameterizations (e.g. boundary layer processes) may offer more near-term advances in Indian Ocean simulations than refined grid resolution.
    Description: Published
    Description: 4A. Oceanografia e clima
    Description: JCR Journal
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 5
    Publication Date: 2022-05-26
    Description: Author Posting. © The Oceanography Society, 2016. This article is posted here by permission of The Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 29, no. 2 (2016): 14–17, doi:10.5670/oceanog.2016.34.
    Description: The Bay of Bengal has a surprisingly large influence on the world. It nurtures the South Asian summer monsoon, a tremendous ocean-atmosphere-land phenomenon that delivers freshwater to more than a third of the human population on this planet. During summer, southwesterly winds gather moisture from the ocean and carry it deep inland over the Indian subcontinent, bringing welcome rains to a parched land. During winter, the winds reverse to northeasterly, and the ocean circulation responds by dispersing the terrestrial freshwater runoff concentrated in the northern part of the bay. This freshwater impacts the ocean’s structure, circulation, and biogeochemistry in numerous ways and, through modification of sea surface temperature, feeds back to influence air-sea fluxes. Because the atmosphere obtains its moisture and heat for convection from the ocean, the interplay between ocean and atmosphere is crucial for the development and sustenance of the monsoon.
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 6
    Publication Date: 2022-05-26
    Description: Author Posting. © The Oceanography Society, 2016. This article is posted here by permission of The Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 29, no. 2 (2016): 50–61, doi:10.5670/oceanog.2016.38.
    Description: Upper-ocean turbulent heat fluxes in the Bay of Bengal and the Arctic Ocean drive regional monsoons and sea ice melt, respectively, important issues of societal interest. In both cases, accurate prediction of these heat transports depends on proper representation of the small-scale structure of vertical stratification, which in turn is created by a host of complex submesoscale processes. Though half a world apart and having dramatically different temperatures, there are surprising similarities between the two: both have (1) very fresh surface layers that are largely decoupled from the ocean below by a sharp halocline barrier, (2) evidence of interleaving lateral and vertical gradients that set upper-ocean stratification, and (3) vertical turbulent heat fluxes within the upper ocean that respond sensitively to these structures. However, there are clear differences in each ocean’s horizontal scales of variability, suggesting that despite similar background states, the sharpening and evolution of mesoscale gradients at convergence zones plays out quite differently. Here, we conduct a qualitative and statistical comparison of these two seas, with the goal of bringing to light fundamental underlying dynamics that will hopefully improve the accuracy of forecast models in both parts of the world.
    Description: We gratefully acknowledge support from the Office of Naval Research, the National Science Foundation, and the Ocean Mixing and Monsoon (OMM) program of the Monsoon Mission of India.
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 7
    Publication Date: 2022-05-26
    Description: Author Posting. © American Meteorological Society, 2019. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Climate 32(2), (2019): 549-573. doi: 10.1175/JCLI-D-18-0413.1.
    Description: Time series of surface meteorology and air–sea fluxes from the northern Bay of Bengal are analyzed, quantifying annual and seasonal means, variability, and the potential for surface fluxes to contribute significantly to variability in surface temperature and salinity. Strong signals were associated with solar insolation and its modulation by cloud cover, and, in the 5- to 50-day range, with intraseasonal oscillations (ISOs). The northeast (NE) monsoon (DJF) was typically cloud free, with strong latent heat loss and several moderate wind events, and had the only seasonal mean ocean heat loss. The spring intermonsoon (MAM) was cloud free and had light winds and the strongest ocean heating. Strong ISOs and Tropical Cyclone Komen were seen in the southwest (SW) monsoon (JJA), when 65% of the 2.2-m total rain fell, and oceanic mean heating was small. The fall intermonsoon (SON) initially had moderate convective systems and mean ocean heating, with a transition to drier winds and mean ocean heat loss in the last month. Observed surface freshwater flux applied to a layer of the observed thickness produced drops in salinity with timing and magnitude similar to the initial drops in salinity in the summer monsoon, but did not reproduce the salinity variability of the fall intermonsoon. Observed surface heat flux has the potential to cause the temperature trends of the different seasons, but uncertainty in how shortwave radiation is absorbed in the upper ocean limits quantifying the role of surface forcing in the evolution of mixed layer temperature.
    Description: The deployment of the Woods Hole Oceanographic Institution (WHOI) mooring and RW and JTF were supported by the U.S. Office of Naval Research, Grant N00014-13-1-0453. DS acknowledges support from the Ministry of Earth Sciences under India’s National Monsoon Mission. HS acknowledges support from the Office of Naval Research Grants N00014-13-1-0453 and N00014-17-12398. The deployment of the WHOI mooring was done by RV Sagar Nidhi and the recovery by RV Sagar Kanya; the help of the crew and science parties is gratefully acknowledged as is the ongoing support at NIOT in Chennai and by other colleagues in India of this mooring work. The work of the staff of the WHOI Upper Ocean Process Group in the design, building, deployment, and recovery of the mooring and in processing the data is gratefully acknowledged. The software for the wavelet analysis was provided by Torrence and Compo (1998). Feedback on the paper by Dr. Amit Tandon and two anonymous reviewers is gratefully acknowledged. This paper is dedicated to Dr. Frank Bradley.
    Description: 2019-06-28
    Keywords: Atmosphere-ocean interaction ; Monsoons ; Air-sea interaction ; Surface fluxes
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 8
    Publication Date: 2022-05-26
    Description: Author Posting. © The Oceanography Society, 2016. This article is posted here by permission of The Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 29, no. 2 (2016): 214–221, doi:10.5670/oceanog.2016.53.
    Description: The Bay of Bengal (BoB), a semi-enclosed basin in the northern Indian Ocean, is a complex region with large freshwater inputs and strong vertical stratification that result in a shallow, spatially variable mixed layer. With the exception of shortwave insolation, the air-sea heat exchange occurs at the sea surface and is vertically redistributed by mixing and advection. Strongly stratified, shallow mixed layers inhibit vertical mixing, and the penetration of solar radiation through the base of the mixed layer can lead to redistribution of upper-ocean heat. This paper compiles observations of hyperspectral downwelling irradiance (Ed) from 67 profiles collected during six research cruises in the BoB that span a broad range of regions and seasons between 2009 and 2014. We report attenuation length scales computed using double and single exponential models and quantify the penetration of radiative flux below the mixed layer depth (Qpen). We then evaluate estimates of Qpen obtained from published chlorophyll-based models and compare them to our observations. We find that the largest penetrative heat flux (up to 40% of the incident Ed) occurs near 16°N where the mixed layers are shallow and the water is optically clear.
    Description: AAL acknowledges funding of the Ocean Mixing and Monsoon (OMM) and SATellite Coastal and Oceanographic REsearch (SATCORE) programs by the Ministry of Earth Sciences, government of India. MMO was supported by the Office of Naval Researchfunded Coastal and Submesoscale Process Studies for Air-Sea Interactions Regional Initiative (ASIRI) in the Bay of Bengal.
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 9
    Publication Date: 2022-05-26
    Description: Author Posting. © The Oceanography Society, 2016. This article is posted here by permission of The Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 29, no. 2 (2016): 134–145, doi:10.5670/oceanog.2016.46.
    Description: The structure and variability of upper-ocean properties in the Bay of Bengal (BoB) modulate air-sea interactions, which profoundly influence the pattern and intensity of monsoonal precipitation across the Indian subcontinent. In turn, the bay receives a massive amount of freshwater through river input at its boundaries and from heavy local rainfall, leading to a salinity-stratified surface ocean and shallow mixed layers. Small-scale oceanographic processes that drive variability in near-surface BoB waters complicate the tight coupling between ocean and atmosphere implicit in this seasonal feedback. Unraveling these ocean dynamics and their impact on air-sea interactions is critical to improving the forecasting of intraseasonal variability in the southwest monsoon. To that end, we deployed a wave-powered, rapidly profiling system capable of measuring the structure and variability of the upper 100 m of the BoB. The evolution of upper-ocean structure along the trajectory of the instrument’s roughly two-week drift, along with direct estimates of vertical fluxes of salt and heat, permit assessment of the contributions of various phenomena to temporal and spatial variability in the surface mixed layer depth. Further, these observations suggest that the particular “barrier-layer” stratification found in the BoB may decrease the influence of the wind on mixing processes in the interior, thus isolating the upper ocean from the interior below, and tightening its coupling to the atmosphere above.
    Description: This work was accomplished with Office of Naval Research support under the umbrella of the Air-Sea Interactions Regional Initiative (ASIRI). AJL was specifically supported by ONR Grant N00014-13-1-0489.
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 10
    Publication Date: 2022-05-26
    Description: Author Posting. © The Oceanography Society, 2016. This article is posted here by permission of The Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 29, no. 2 (2016): 242–253, doi:10.5670/oceanog.2016.56.
    Description: Because the monsoon strongly affects India, there is a clear need for indigenous expertise in advancing the science that underlies monsoon prediction. The safety of marine transport in the tropics relies on accurate atmospheric and ocean environment predictions on weekly and longer time scales in the Indian Ocean. This need to better forecast the monsoon motivates the United States to advance basic research and support training of early career US scientists in tropical oceanography. Earlier Indian field campaigns and modeling studies indicated that an improved understanding of the interactions between the upper ocean and the atmosphere in the Bay of Bengal at finer spatial and temporal scales could lead to improved intraseasonal monsoon forecasts. The joint US Air-Sea Interactions Regional Initiative (ASIRI) and the Indian Ocean Mixing and Monsoon (OMM) program studied these interactions, resulting in scientific advances described by articles in this special issue of Oceanography. In addition to these scientific advances, and while also developing long-lasting collaborations and building indigenous Indian capability, a key component of these programs is training early career scientists from India and the United States. Training has been focusing on fine-scale and mixing studies of the upper ocean, air-sea interactions, and marine mammal research. Advanced methods in instrumentation, autonomous robotic platforms, experimental design, data analysis, and modeling have been emphasized. Students and scientists from India and the United States at all levels have been participating in joint cruises on Indian and US research vessels and in training participants in modern tools and methods at summer schools, at focused research workshops, and during research visits. Such activities are building new indigenous capability in India, training a new cadre of US scientists well versed in monsoon air-sea interaction, and forging strong links between Indian and US oceanographic institutions.
    Description: We are grateful for the support of the administration of NARA
    Repository Name: Woods Hole Open Access Server
    Type: Article
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