Schlagwort(e):
Electronic books.
Materialart:
Online-Ressource
Seiten:
1 online resource (264 pages)
Ausgabe:
1st ed.
ISBN:
9781536188554
Serie:
Advances in Chemistry Research Series
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=6382627
Sprache:
Englisch
Anmerkung:
Intro -- Contents -- Preface -- Chapter 1 -- Water-in-Oil Microemulsions: An Overview -- Abstract -- 1. Introduction -- 2. Historical Background -- 3. Properties -- 3.1. Definition -- 3.2. Components -- 3.2.1. Water -- 3.2.2. Oil -- 3.2.3. Surfactants -- 3.2.4. Cosurfactants -- 3.3. Formation Theories -- 4. Characterization -- 4.1. Phase Diagrams -- 4.2. Physical-Chemical Methods -- 5. Applications -- 5.1. Electroanalysis -- 5.2. Organic and Inorganic Electrosynthesis -- 5.3. Pharmaceuticals and Cosmetics -- 5.4. Food Applications -- 5.5. Miscellaneous -- 6. Surfactant-Free Water-in-Oil Microemulsions -- 6.1. Components -- 6.2. Formation Theory -- 6.3. Application in Electroanalysis -- Conclusion -- References -- Chapter 2 -- Understanding and Resolving the Manifested Resistance to Azoles -- Abstract -- 1. Introduction -- 2. Resistance to Azole Compounds -- 2.1. Molecular Basis of Azole Action Mechanism -- 2.2. Target Site Modulation Driven Attenuated Functioning of Azoles -- 2.3. Resistance Mechanisms of Azoles -- 2.3.1. Azole Import -- 2.3.2. ERG11 Mutation -- 2.3.3. Erg11 Overexpression -- 2.3.4. Variations in Ergosterol Bio-formation -- 2.3.5. Azole Efflux -- 2.3.6. Sterol Import -- 2.3.7. Biofilms -- 2.3.8. Genetic Abnormalities -- 2.3.9. Heat-Shock Proteins -- 3. Resistance Mechanisms Functional in Clinical Drugs -- 4. Prominent Applications of Azole Compounds -- 4.1. Antimicrobial Action -- 4.2. Pharmacokinetics of Azoles -- 4.3. Anti-inflammatory Action of Azoles -- 4.4. Azoles for Cancer Treatment -- 4.5. Azoles for the Treatment of Dermatophytosis -- 4.6. Peptide-Azole Conjugate: A Potential Agent against Cryptococcosis -- 4.7. Agricultural Significance of Azoles -- 4.8. Aminoisoxazoles as Potent Tryptophan 2,3-Dioxygenase 2 (TDO2) Inhibitors -- 4.9. Stereochemistry Dictated Antiangiogenic and Antifungal Actions of Itraconazole.
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4.10. Potential Antimicrobial Isopropanol-Conjugated Carbazoles as Dual Targeting Enterococcus Faecalis Inhibitors -- 4.11. Special Study on Medicinal Aspects of Azoles -- Conclusion and Future Directions -- References -- Chapter 3 -- Total Syntheses of Biologically Active Natural Products Directed Toward Drug Discovery -- Abstract -- Introduction -- Total Synthesis of Lipid-Related Compound -- Total Synthesis of Shizostatin, a Potent Squalene Synthase Inhibitor -- Total Synthesis of Plaunotol, an Antibacterial Agent against Helicobacter Pylori -- Total Synthesis of Plaunotol via Suzuki-Miyaura Coupling -- Total Synthesis of Plaunotol via Wittig reaction -- Synthesis of Plaunotol Thiourea Derivatives and Their Antibacterial Activities against H. Pylori -- Total Synthesis of Alutacenoic Acids A and B, a Potent Factor XIIIa Inhibitors -- Total Synthesis of Lissoclinolide via Regioselective 5-Exo Lactonization -- Total Synthesis of Cyclic Depsipeptide Antibiotics -- Total Synthesis of Globomycin, a Signal Peptidase II Inhibitor -- Retrosynthetic of Analysis of Globomycin -- Synthesis of Fragment A and B -- Synthesis of Fragment C -- Synthesis of Globomycin via Macrolactonization -- Antibacterial Activities of Globomaicin Analogues -- Total Synthesis of Pleofungin A, a Potent Inositol Phosphorylceramide Synthase Inhibitor -- Retrosynthetic of Analysis of Pleofungin A -- Synthesis of Tetrapeptide Component 2-23 -- Synthesis of Hexapeptide Component -- Synthesis of Pleofungin A via Macrocyclization -- Total Synthesis of Nitrogen Containing Heterocyclic Natural Products -- Total Synthesis of Benzastatin E -- Synthesis of Benzastatin E via Diastereoselective Grignard Addition -- Total Synthesis of Virantmycin -- Hypothetical Biosynthetic Pathway from Benzastatin to Virantmycin.
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Stereospecific Rearrangement from Indoline to Tetrahydroquinoline Skeleton Based on Biosynthetic Hypothesis -- Total Synthesis of (-)-Virantmycin via the Ring Expansion Rearrangement -- Total Synthesis of Phaeosphaeride Family -- Structure Elucidation of Phaeosphaeride A, an Inhibitor of STAT3 -- Total Synthesis of (-)-Phaeosphaeride A -- Synthesis of (-)-Phaeosphaeride B by a Biomimetic Conversion -- Synthesis of the Proposed Structure of Paraphaeosphaeride C -- Total Synthesis of Epoxy- -Lactam Natural Product -- Total Synthesis of Epolactaene, a Nuritogenic Agent -- Retrosynthetic Analysisi of Epolactaene -- Development of Diastereoselective Aldol Reaction between -alkoxy aldeyde and Malonate Ester -- Synthesis of the Left Part of Epolactaene -- Synthesis of Wittig Reagent -- Completion of the Total Synthesis of Epolactaene -- Total Synthesis of L-755,807, a Nuritogenic Agent -- Initial Stereochemical Consideration of L-755,807 -- Retrosynthetic Analysis of L-755,807 -- Development of Diastereoselective Darzens Condensation -- Synthesis of Phosphonate 4-25 via Darzens Condensation -- Synthesis of Side-Chain Segment of L-755,807 -- Completion of the Total Synthesis of L-755,807 -- Amyloid Aggregation Inhibitory Activity of the Synthetic Compounds -- Conclusion -- References -- Biographical Sketch -- Chapter 4 -- Methanol to Gasoline: A Sustainable Transport Fuel -- Abstract -- 1. Introduction -- 1.1. The U.S. Methanol Market -- 1.2. Global Marketing and Production Methanol -- 1.3. Methanol Manufacturing in Iran -- 2. Methanol Synthesis Catalysts from Gas Synthesis -- 3. Methanol Properties -- 4. Methanol Applications -- 5. The Methanol to Olefins Process -- 6. The Methanol to Gasoline Process -- Conclusion -- References -- Contents of Earlier Volumes -- Index -- Blank Page -- Blank Page.
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