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  • Blackwell Publishing Ltd  (5)
  • International Union of Crystallography (IUCr)  (1)
  • 2000-2004  (1)
  • 1990-1994  (5)
Document type
Publisher
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Techniques in immuno-electron microscopy (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 21 (1994), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Normal skin was cryoprotected by submerging it in a mixture of 30% dimethylformamide (DMF) in PBS or RPMI. Subsequently it was frozen in liquid propane gas. Cryosubstitution was carried out at −90°C by using methanol to which uranyl acetate or osmium tetroxide were added. The tissue was embedded in either Lowicryl K4M at −40°C or in Epon at +60°C. The- tissue was evaluated by its overall preservation of ultras-tructural details and by its labeling intensity alter incubation with either anti-clesmoglein or anti-type VII collagen monoclonal antibodies. The mixture of DMF and PBS caused an electron-dense precipitate within the cell. The overall morphology was better in Epon-embedded material than in K4M-embedclecl material. However, the labeling was best in K4M material. Regardless of whether the tissue was embedded in Epon or K4M, the addition of osmium tetroxide markedly reduced the degree of labeling.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1994.tb00708.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Possible association between loudness dependence of auditory evoked potentials and tryptophan hydroxylase-alleles in alcoholics (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Addiction biology 5 (2000), S. 0 
    Details
    ISSN: 1369-1600
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The serotonergic neurotransmission was suggested to play an important role in the aetiology of alcoholism. This study explores the association between tryptophan hydroxylase (TPH)-alleles and Loudness Dependence of Auditory Evoked N1/P2 Potentials (LDAEP). The TPH is the rate-limiting biosynthetic enzyme in serotonergic pathway. The LDAEP is one of the best validated non-invasive indicators for serotonergic neurotransmission. A sample of 54 alcoholics was recruited. N1/P2 potentials were evoked by five different sound intensities. A dipole source analysis using BESA (brain electric signal topography) was performed and intensity dependence was computed. The TPH intron 7 polymorphism was determined by using PCR in DNA samples. There was a weak but significant association between low LDAEP and the L-TPH allele. No influence from an individual's history of alcohol dependence or a positive family history of alcohol dependence on LDAEP was found. The weak but significant relationship found between L-TPH-allele and high serotonergic neurotransmission may contribute to a more detailed neurobiological characterization of alcohol dependents using functional and genetic parameters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1369-1600.2000.tb00194.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Congenital self-healing reticulohistiocytosis – A benign Langerhans cell disease (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 21 (1994), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An-11-day old girl was seen with brownish nodular lesions scattered over (he body with emphasis on the face and seal). Several lesions had started lo involute. Tissue was studied by histopathology, immunohistopathology, routine electron microscopy, and immuno-electron microscopy using cryosubstitution and embedding in K4M. Immunohistopathology revealed that the cells of the dermal infiltrate were Langerhans cells. They expressed Leu 6 and HLA-DR. On routine electron microscopy no Birbeck granules were (bund in the dermal cells. Birbeck granules in epidermal Langerhans cells were deformed and often situated next to laminated dense bodies. The latter expressed Leu 6 and HLA-DR. on immuno-electron microscopy. It was concluded that congenital self-healing reticulohistiocytosis is a benign Langerhans cell disease in which Birbeck granules are transformed to laminated dense bodies and possibly degraded by lysosomal enzymes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1994.tb00692.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Larval fish production in the tidal River Elbe 1985–1986 (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 38 (1991), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: In 1985 and 1986 ichthyoplankton composition was studied during seven sampling series at 37 stations along the tidal Elbe and its tributary rivers between Hamburg harbour and the North Sea. The highest larval density was observed in May and April. No, or very few, larvae occurred from late summer to early spring. Smelt (59% on average of all samples) and twaite shad (20%) dominate in the freshwater region. Herring/sprat (17%) dominate in the estuary. All major spawning grounds are located along the southern shore. Smelt spawn further upstream 1 month earlier than twaite shad. Three percent of all larvae found were flounder. Most of them occurred upstream from the estuary in the R. Este and in other tributary rivers. It is not clear whether flounders are able to spawn in freshwater. Attention is drawn to the fact that an unknown but probably very high percentage of the ichthyoplankton is entrained by local power plants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.1991.tb03622.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Avoidance of oxygen-poor zones by fish in the Elbe River (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of applied ichthyology 7 (1991), S. 0 
    Details
    ISSN: 1439-0426
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: For three selected weeks in July, August, and October 1985, catches from anchor net vessels at ten stations along the tidal Elbe River (northern Germany) were analyzed and related to oxygen conditions in the river. The oxygen concentrations decreased from an average of 6.6 ml/L in the estuary to an average of 1.4 mg/L upstream. Fish were found to be concentrated downstream from the low-oxygen zone and at the entrance to a shallow side arm of the main stream. Highest catches of eel were made where oxygen levels were in the range of 1.2–3 mg/L, highest catches of flounder at 3–4 mg/L, and highest catches of juvenile and adult smelt in areas with more than 5 mgO2/L. Such a situation enables fishermen to make extraordinarily high catches. It is concluded that despite high levels of toxicants, the tidal Elbe still offers living conditions adequate for the mass of fish species as long as there is a sufficient supply of oxygen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0426.1991.tb00524.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Profile structure refinement of SrCl2.2D2O by neutron powder diffraction (1993)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 49 (1993), S. 944-946 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270192011806
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    Paper (German National Licenses)
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