Beschreibung: Cruise POS500 “LISA” with R/V Poseidon studied the western Ligurian Margin off Southern France, an area in the northeastern part of the western Mediterranean Sea characterized by its active tectonism and frequent mass wasting. The region near the Var estuary close to the city of Nice is particularly suited for landslide research because it represents a natural laboratority where it is possible to study a series of trigger processes of geological and anthropogenic origin. The aim of this MARUM expedition was to: i. Study fresh water seepage in the marine Nice airport landslide and adjacent stable plateau in 15-50 m water depth using water sampling, CTD and geochemistry; ii. Recover and deploy a number of observatories that monitor, pressure, temperature, tilt and seismicity; iii. Run an AUV micro-bathymetric survey with MARUM AUV SEAL5000 to complement existing multibeam maps; and iv. Acquire additional high-resolution seismic reflection profiles to unravel the complex architecture of the Nice slope and Var delta. In a period of approximately two weeks, we acquired valuable geophysical information that helps to understand the evolution of this portion of the Ligurian Margin and further to support an active Amphibious Drilling proposal submitted to ICDP and IODP. We could also show that heavy spring rainfall plus melt water from the French Maritime Alps supplied sufficient hydraulic forcing to push Var aquifer groundwaters to seep into the marine deposits and water column. Freshening was strongest in the 1979 Nice landslide scar, but was also found at the outer edge of the shelf. Recovery and redeployment of various observatory prototypes worked well, both for the MARUM MeBo seafloor drillstring tolos and independent piezometers. Observatory data have yet to be evaluated. In addition, geochemical analyses of bottom waters and pore waters was deferred to shore-based laboratorios except for salinity estimates using a refractometer. Seismic processing was started onboard, but is largely taking place post-cruise at University Bremen.