ISSN:
1440-1681
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
1. The effect of treatment with 9α-fluorocortisol (9aFF), a steroid which causes hypertension in sheep, was examined in sheep with ACTH-induced hypertension.2. ACTH treatment alone increased mean arterial pressure (MAP), plasma Na concentration, water intake and urine volume and decreased plasma K concentration.3. 9αFF treatment, for 3 days during continuing ACTH administration, did not change blood pressure but increased heart rate, water intake and urine volume and decreased urinary K excretion.4. As 9αFF did not cause a further increment in blood pressure in sheep with ACTH-induced hypertension it is possible that both ACTH and 9αFF may produce hypertension by similar mechanisms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1440-1681.1985.tb00912.x