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Microbiology A triclosan-resistant bacterial enzyme (2000)

Heath, Richard J. ; Rock, Charles O.

[s.l.] : Macmillan Magazines Ltd.

Nature 406 (2000), S. 145-146

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] Triclosan is an antimicrobial agent that is widely used in a variety of consumer products and acts by inhibiting one of the highly conserved enzymes (enoyl-ACP reductase, or FabI) of bacterial fatty-acid biosynthesis. But several key pathogenic bacteria do not possess FabI, and here we describe ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/35018162

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