In:
Prenatal Diagnosis, Wiley, Vol. 12, No. 5 ( 1992-05), p. 347-355
Abstract:
Cytogenetic data from the United States NICHD collaborative study of chorionic villus sampling (CVS) were used to evaluate the clinical significance of chorionic mosaicism. The 10 754 patients with normal cytogenetic results were compared wtih 108 patients (1.0 per cent) with placental mosaicism and 181 patients (1.6 per cent) with pseudomosaicism. Of the pregnancies intended to continue, the pregnancy loss rate was significantly greater in patients with placental mosaicism than in the cytogenetically normal cohort (8.6 vs. 3.4 per cent, p 〈 0.05). However, there was no difference in the frequencies of abruptio placenta, preterm labour or delivery, small‐for‐gestational‐age newborns, pregnancy‐induced hypertension, or neonates with Apgar scores less than 7.
Type of Medium:
Online Resource
ISSN:
0197-3851
,
1097-0223
DOI:
10.1002/pd.1970120504
Language:
English
Publisher:
Wiley
Publication Date:
1992
detail.hit.zdb_id:
1491217-X