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  • Wiley  (27)
  • 1
    Online-Ressource
    Online-Ressource
    Wiley ; 2018
    In:  Journal of Food Science Vol. 83, No. 6 ( 2018-06), p. 1740-1747
    In: Journal of Food Science, Wiley, Vol. 83, No. 6 ( 2018-06), p. 1740-1747
    Kurzfassung: Nano cellulose is attracting great interest in food and nutraceutical fields and also provides a potential additive to develop functional meat products such as low fat sausage. Here, we compared 1 wt% aqueous dispersion of cellulose nanofiber (CNF) and its palm oil Pickering emulsion (CPOE) at the ratio of 1:1 (water: oil, v:v) for being fat alternatives replacing 30% and 50% of the original fat of the emulsified sausage. Replacing fat by CPOE and CNF resulted in lower fat content, lower cooking loss and higher moisture content and higher lightness values ( P ≤ 0.05) at both fat levels. Textural analysis indicated that the products formulated with CPOE showed higher hardness, springiness, chewiness and the texture was enhanced by the addition of CNF, especially when 30% fat was substituted. Compared with the full‐fat control, the sausages formulated with CPOE became more elastic and compact, especially by the incorporation of CNF according to the rheology and scanning electron microscope results. The reformulated products with CPOE and CNF at the 30% level showed higher sensory scores ( P ≤ 0.05) while at the 50% level produced comparable quality to the control, but no significant differences were found in the overall acceptability. In summary, CNF and its Pickering emulsion provide the potential as potential fat alternatives for developing low fat meat products. Practical Applications Cellulose nanofibers present a variety of distinguishing properties, such as large surface area, great stability and high strength. The ability to stabilize emulsions and good biocompatibility enlarge its application in food. In this study, we attempted to use cellulose nanofibers and its palm oil Pickering emulsion as fat substitutes to partly replace the original fat of pork emulsified sausages, hoping to provide some basic information for using cellulose nanofibers and its Pickering emulsion as fat substitute to high fiber, low fat meat products.
    Materialart: Online-Ressource
    ISSN: 0022-1147 , 1750-3841
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2018
    ZDB Id: 2006705-7
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    Online-Ressource
    Online-Ressource
    Wiley ; 2018
    In:  Journal of Texture Studies Vol. 49, No. 3 ( 2018-06), p. 300-308
    In: Journal of Texture Studies, Wiley, Vol. 49, No. 3 ( 2018-06), p. 300-308
    Kurzfassung: It is a challenge for producers to looking for excellent filler to satisfy the required qualities of high grade meat products such as Harbin red sausage in China. Four collagen superfine powders (CSPs) from pig skin with different heating pretreatments, named as T0 (non‐heating), T1 (at 60C for 20 min), T2 (at 80C for 20 min), T3 (at 120C for 10 min), respectively, at various concentrations (1, 3, 5 wt %) were added to the sausage and their impact on sausage properties was investigated. Rheological results showed that addition of CSPs especially T2 increased the elastic modulus ( G ′) of sausage, indicating the enhanced stabilization of meat batter due to formation of a coherent protein network. Furthermore, as the content of CSPs increased, the values of hardness, springiness, cohesiveness, and chewiness of the CSP‐added sausages increased from texture profile analysis. Meantime, it was observed that appropriate preheating (i.e., lower than 80C for 20 min) benefited the texture profile of the sausages. With adding these CSPs, the cooking loss decreased, the values of L * and a * decreased while b * value of the sausages increased. SEM images illustrated that the CSP‐added sausage was more compact and homogenous compared to the control. Also, the organoleptic evaluation results showed that the sensory properties of Harbin red sausage added CSP were the same as the control group. In conclusion, CSPs provide the potential to be used as a filler and textural modifier available for Harbin red sausage. Practical applications Pig skin has cheap price, and easy to get. Pig skin‐derived CSPs provide the potential to be used as a good filler and textured modifier available for high quality meat products, including Harbin red sausage.
    Materialart: Online-Ressource
    ISSN: 0022-4901 , 1745-4603
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2018
    ZDB Id: 2176283-1
    SSG: 15,3
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    In: ChemInform, Wiley, Vol. 36, No. 38 ( 2005-09-20)
    Materialart: Online-Ressource
    ISSN: 0931-7597 , 1522-2667
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2005
    ZDB Id: 2110203-X
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
    In: ESC Heart Failure, Wiley
    Kurzfassung: The combination of haemoglobin, albumin, lymphocytes, and platelets (HALP) is a new metric used to assess patient prognosis in many diseases. This study aimed to assess the relationship between HALP and short‐ and long‐term mortality in patients with heart failure. Methods and results This retrospective cohort study included adult patients with heart failure who were hospitalized between 2019 and 2021. The primary outcomes were 1‐month mortality and 1‐year mortality. The multivariable logistic regression analysis was used to evaluate the association between HALP and the risk of mortality. Stratified analyses were conducted based on New York Heart Association functional classification (NYHA) stage (II/III, IV) and left ventricular ejection fraction (LVEF, 〈 50%, ≥50%). The area under the receiver operating characteristic curve (AUC) was used to evaluate the ability of HALP, prognostic nutritional index (PNI), C‐reactive protein (CRP), and the Meta‐Analysis Global Group in Chronic Heart Failure (MAGGIC‐HF) risk score in predicting mortality in patients with heart failure. A total of 730 patients with heart failure were included, of whom 61 (8.36%) died within 1 month and 77 (10.55%) died within 1 year. High HALP scores were associated with a reduced risk of 1‐month mortality (odds ratio (OR) = 0.978, 95% confidence interval (CI): 0.963–0.992, P  = 0.003) and 1‐year mortality (OR = 0.987, 95% CI: 0.977–0.997, P  = 0.009) in patients with heart failure. In patients with different NYHA stages or LVEF levels, high HALP scores were correlated with a reduced risk of 1‐year mortality in patients with NYHA stage II/III (OR = 0.978, 95% CI: 0.957–1.000, P  = 0.045) or LVEF ≥50% (OR = 0.970, 95% CI: 0.945–0.996, P  = 0.024). The AUC for HALP, PNI, CRP, and MAGGIC‐HF to predict 1‐year mortality in patients with heart failure were 0.677 (95% CI: 0.619–0.735), 0.666 (95% CI: 0.608–0.723), 0.638 (95% CI: 0.572–0.704), and 0.654 (95% CI: 0.591–0.717), respectively. Conclusions HALP may be a potential marker for predicting mortality in patients with heart failure. Further exploration based on HALP may yield better clinical predictors of prognosis in patients with heart failure.
    Materialart: Online-Ressource
    ISSN: 2055-5822 , 2055-5822
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2024
    ZDB Id: 2814355-3
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
    Online-Ressource
    Online-Ressource
    Wiley ; 2007
    In:  ChemInform Vol. 38, No. 47 ( 2007-11-20)
    In: ChemInform, Wiley, Vol. 38, No. 47 ( 2007-11-20)
    Materialart: Online-Ressource
    ISSN: 0931-7597 , 1522-2667
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2007
    ZDB Id: 2110203-X
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
    In: Human Brain Mapping, Wiley, Vol. 42, No. 15 ( 2021-10-15), p. 5154-5169
    Kurzfassung: Anorexia nervosa (AN) is a complex psychiatric disorder with poorly understood etiology. Numerous voxel‐based morphometry (VBM) and resting‐state functional imaging studies have provided strong evidence of abnormal brain structure and intrinsic and functional activities in AN, but with inconsistent conclusions. Herein, a whole‐brain meta‐analysis was conducted on VBM (660 patients with AN, and 740 controls) and resting‐state functional imaging (425 patients with AN, and 461 controls) studies that measured differences in the gray matter volume (GMV) and intrinsic functional activity between patients with AN and healthy controls (HCs). Overall, patients with AN displayed decreased GMV in the bilateral median cingulate cortex (extending to the bilateral anterior and posterior cingulate cortex), and left middle occipital gyrus (extending to the left inferior parietal lobe). In resting‐state functional imaging studies, patients with AN displayed decreased resting‐state functional activity in the bilateral anterior cingulate cortex and bilateral median cingulate cortex, and increased resting‐state functional activity in the right parahippocampal gyrus. This multimodal meta‐analysis identified reductions of gray matter and functional activity in the anterior and median cingulate in patients with AN, which contributes to further understanding of the pathophysiology of AN.
    Materialart: Online-Ressource
    ISSN: 1065-9471 , 1097-0193
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2021
    ZDB Id: 1492703-2
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
    Online-Ressource
    Online-Ressource
    Wiley ; 2021
    In:  Journal of Neuroscience Research Vol. 99, No. 3 ( 2021-03), p. 858-871
    In: Journal of Neuroscience Research, Wiley, Vol. 99, No. 3 ( 2021-03), p. 858-871
    Kurzfassung: Traditional repetitive transcranial magnetic stimulation can only produce a significant but weak effect on the cortex while theta burst stimulation (TBS), a patterned accelerated form of stimulation, can produce a stronger poststimulation effect, which may improve decision‐making abilities. We designed a comparative assessment of the effect of intermittent TBS (iTBS), 20 Hz, in two risk decision‐making tasks on healthy controls. Participants were randomized and assigned to the iTBS ( n  = 29), 20 Hz ( n  = 29), or sham ( n  = 29) groups. The effects of the different methods of left dorsolateral prefrontal cortex stimulation on risk decision‐making functions were compared based on subjects’ performance in the Game of Dice Task (GDT) and Risky Gains Task (RGT). The main indicators were positive and negative feedback utilization rates of GDT and RGT. Both iTBS and 20 Hz stimulation resulted in significant improvements upon negative feedback in the GDT, with increases in safe options and reductions in risky options; iTBS stimulation increased subjects’ use of positive feedback in the GDT and RGT (all p   〈  0.05). Furthermore, the iTBS group had a stronger feedback risk reduction effect than the 20 Hz or sham group following RGT negative feedback ( p   〈  0.05). Individuals would integrate positive and negative information more efficiently, leading to them making rational choices after excitatory transcranial magnetic stimulation. Moreover, iTBS has a stronger risk reduction effect following negative feedback than the 20Hz stimulation did. In summary, iTBS might have clinical value in decision promotion.
    Materialart: Online-Ressource
    ISSN: 0360-4012 , 1097-4547
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2021
    ZDB Id: 1474904-X
    SSG: 12
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
    In: The FASEB Journal, Wiley, Vol. 23, No. S1 ( 2009-04)
    Materialart: Online-Ressource
    ISSN: 0892-6638 , 1530-6860
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2009
    ZDB Id: 1468876-1
    SSG: 12
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 9
    In: Annals of Neurology, Wiley, Vol. 94, No. 4 ( 2023-10), p. 672-683
    Kurzfassung: Emerging pathological evidence suggests that there is an association between glymphatic dysfunction and the progression of Parkinson's disease (PD). However, the clinical evidence of this association remains lacking. Methods In this study, the index for diffusion tensor image analysis along the perivascular space (ALPS index) was calculated to evaluate glymphatic function. Results Overall, 289 patients with PD were enrolled in the cross‐sectional study. The ALPS index was found to be negatively correlated with age, disease severity, and dyskinesia. In the longitudinal study, the information on a total of 95 PD patients with 5‐year follow‐up examinations was collected from the Parkinson's Progression Marker Initiative, 33 of which were classified into the low ALPS index group, and all others were classified into the mid‐high ALPS index group based on the first tertile of the baseline ALPS index. The results of longitudinal regression indicated that there was a significant main group effect on autonomic dysfunction, as well as on activities of daily living. In addition, the low ALPS index group had faster deterioration in MDS‐UPDRS part III and part II, Symbol Digit Modalities Test and Hopkins Verbal Learning Test. Path analysis showed that ALPS index acted as a significant mediator between tTau/ Aβ 1‐42 and cognitive change in the Symbol Digit Modalities Test score at year 4 and year 5. Interpretation The ALPS index, an neuroimaging marker of glymphatic function, is correlated with PD disease severity, motor symptoms, and autonomic function, and is predictive of faster deterioration in motor symptoms and cognitive function. Additionally, glymphatic function may mediate the pathological role of toxic protein in cognitive decline. ANN NEUROL 2023;94:672–683
    Materialart: Online-Ressource
    ISSN: 0364-5134 , 1531-8249
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2023
    ZDB Id: 2037912-2
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 10
    In: genesis, Wiley, Vol. 56, No. 4 ( 2018-04)
    Kurzfassung: Placental development is a complex and highly controlled process during which trophoblast stem cells differentiate to various trophoblast subtypes. The early embryonic death of systemic gene knockout models hampers the investigation of these genes that might play important roles during placentation. A trophoblast specific Cre mouse model would be of great help for dissecting out the potential roles of these genes during placental development. For this purpose, we generate a transgenic mouse with the Cre recombinase inserted into the endogenous locus of Elf5 gene that is expressed specifically in placental trophoblast cells. To analyze the specificity and efficiency of Cre recombinase activity in Elf5‐Cre mice, we mated Elf5‐Cre mice with Rosa26 mT/mG reporter mice, and found that Elf5‐Cre transgene is expressed specifically in the trophoectoderm as early as embryonic day 4.5 (E4.5). By E12.5, the activity of Elf5‐Cre transgene was detected exclusively in all derivatives of trophoblast lineages, including spongiotrophoblast, giant cells, and labyrinth trophoblasts. In addition, Elf5‐Cre transgene was also active during spermatogenesis, from spermatids to mature sperms, which is consistent with the endogenous Elf5 expression in testis. Collectively, our results provide a unique tool to delete specific genes selectively and efficiently in trophoblast lineage during placentation.
    Materialart: Online-Ressource
    ISSN: 1526-954X , 1526-968X
    URL: Issue
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2018
    ZDB Id: 2019664-7
    SSG: 12
    Standort Signatur Einschränkungen Verfügbarkeit
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