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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 84 (1998), S. 5811-5813 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: This communication describes the diffusion of sulfur into Ga1−xAlxAs layers having various amounts of Al content. GaS and As in a weight ratio of 2:1 were used as the diffusion source. The GaS diffusion source was carefully selected via x-ray diffraction analysis. Sulfur diffusion was carried out in a sealed quartz ampoule at a temperature of 820 °C and in ambient arsenic at a vapor pressure of 1 atm. Ga1−xAlxAs layers of various x values were grown by liquid phase epitaxy. The Al content indicated by x was in the range of 0–0.3. For x values of 0, 0.08, 0.2, and 0.3, the surface concentrations and diffusion coefficients were found to be 1.0×1018, 3.8×1017, 2.0×1017, and 1.4×1011 cm−3, and 3.5×10−13, 2.0×10−12, 3.5×10−12, and 5.5×10−12 cm2/s, respectively. The carrier concentration profiles from the experimental results agree well with the theoretical profiles, which were calculated with the complementary error function solution. The activation energies of the diffusion coefficient in GaAs and Ga0.7Al0.3As were found to be about 4.7 and 2.5 eV, respectively. A smooth diffusion of sulfur was observed to occur without causing any surface damage. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 61 (1987), S. 4479-4483 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: This paper contains experimental results on the population of the 21S atom of HeI in the discharge plasma of a He+Xe gas mixture. The population measurement was made by the laser-induced fluorescence method with the laser light tuned to the HeI line of 5016 A(21S-31P). The fluorescence intensity of HeI lines was measured as a function of the mixture ratio of Xe to He gas. As the Xe gas was mixed, the fluorescence intensity was significantly reduced at pressures ranging from 0.2 to 1 Torr. Further, an increment of the discharge current made the population of the 21S atom increase more remarkably in the Xe-mixed gas than in the pure He. These behaviors were considered using the measured temperature and density of the electrons, and it was concluded that at 1-Torr the Penning collision of the 21S atom with Xe was effective and dominated the behavior of the 21S atom.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Melbourne, Australia : Blackwell Science Pty
    The @island arc 13 (2004), S. 0 
    ISSN: 1440-1738
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Abstract  The Upper Cenozoic sedimentary sequences drilled at Sites 1150 and 1151, Ocean Drilling Program Leg 186, enabled establishment of radiolarian zonation and calibration of the age of bioevents in the forearc area of the northern Japan Islands. The sequences were divided into nine zones from the Pleistocene Botryostrobus aquilonaris Zone to the Upper Miocene Lipmanella redondoensis Zone at Site 1150, and 11 zones from the Pleistocene Stylatractus universus Zone to the Middle Miocene Dendrospyris? sakaii Zone at Site 1151. These zones correlate successfully with the studied sequences of many of deep-sea cores in the Northwest Pacific Ocean and with some sections of onshore Japan. Of 67 important radiolarian bioevents recognized during the study, 29 Pleistocene to Upper Miocene events were directly tied to the geomagnetic polarity time scale through the well-defined paleomagnetic polarity records, and 21 Upper Miocene events were calibrated based on the diatom biostratigraphy. Of these events, 24 geographically widespread events were selected to test synchroneity and usefulness as time-horizons within the mid-to-high latitude of the Northwest Pacific, involving eight other offshore and onshore sections. Examination showed that most of the zonal boundary events are synchronous within the considered region, and that many diachronous events, most of which are eliminated from the zonal scheme, are unreliable events linked to rare and sporadic occurrences of the species. Radiolarian biostratigraphy of the studied cores clearly indicates three major hiatuses in the Middle Pleistocene, Late Miocene and late Middle Miocene. The latter two hiatuses can be correlated to two global oceanic hiatuses, NH6 and NH3, respectively.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Melbourne, Australia : Blackwell Science Pty
    The @island arc 14 (2005), S. 0 
    ISSN: 1440-1738
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1440-1738
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Abstract  Shipboard and shore-based investigation on siliceous and calcareous microfossil biostratigraphy, magneto-stratigraphy and tephrostratigraphy identified numerous datum events from the sedimentary sequences of Sites 1150 and 1151 drilled on the forearc basin of northern Japan by the Ocean Drilling Program Leg 186. Some 83 datum events were selected to construct new age–depth models for the sites. Based on the reliable magneto-stratigraphy from the Pleistocene to the Upper Miocene, which were correlated to the standard geomagnetic polarity timescale, and on excellent records of diatom and radiolarian biostratigraphy throughout the sequences, the shipboard age model was revised. Major revisions referred to stratigraphic position of the Miocene–Pliocene boundary that has been shifted more than 200 m downward in each sequence. The age–depth relations of the forearc sites represent drastic changes in the sedimentation rate—extremely high (40 cm/k.y. on average) in the Early Pliocene and low (less than 2 cm/k.y. on average) in the Middle Miocene—and several hiatuses exist throughout the sequence. The drastic changes can be related mostly to changes in diatom sedimentation and the tectonics of the Japanese Island Arc. Local ages for some foraminiferal, calcareous nannofossil and radiolarian bioevents are estimated from the age–depth models at each site. These newly calibrated bioevents and biozones as well as established diatom biostratigraphy are incorporated into the updated magneto-biochronologic timescale, which will contribute to an improvement in biochronologic accuracy of Neogene sediments in northern Japan and adjacent areas.
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 2013-02-27
    Description: Enhanced dihydropyridine receptor calcium channel activity restores muscle strength in JP45/CASQ1 double knockout mice Nature Communications 4, 1541 (2013). doi:10.1038/ncomms2496 Authors: Barbara Mosca, Osvaldo Delbono, Maria Laura Messi, Leda Bergamelli, Zhong-Min Wang, Mirko Vukcevic, Ruben Lopez, Susan Treves, Miyuki Nishi, Hiroshi Takeshima, Cecilia Paolini, Marta Martini, Giorgio Rispoli, Feliciano Protasi & Francesco Zorzato
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2017-08-12
    Description: Aberrant Zn2+ homeostasis is associated with dysregulated intracellular Ca2+ release, resulting in chronic heart failure. In the failing heart a small population of cardiac ryanodine receptors (RyR2) displays sub-conductance-state gating leading to Ca2+ leakage from sarcoplasmic reticulum (SR) stores, which impairs cardiac contractility. Previous evidence suggests contribution of RyR2-independent Ca2+ leakage through an uncharacterized mechanism. We sought to examine the role of Zn2+ in shaping intracellular Ca2+ release in cardiac muscle. Cardiac SR vesicles prepared from sheep or mouse ventricular tissue were incorporated into phospholipid bilayers under voltage-clamp conditions, and the direct action of Zn2+ on RyR2 channel function was examined. Under diastolic conditions, the addition of pathophysiological concentrations of Zn2+ (≥2 nm) caused dysregulated RyR2-channel openings. Our data also revealed that RyR2 channels are not the only SR Ca2+-permeable channels regulated by Zn2+. Elevating the cytosolic Zn2+ concentration to 1 nm increased the activity of the transmembrane protein mitsugumin 23 (MG23). The current amplitude of the MG23 full-open state was consistent with that previously reported for RyR2 sub-conductance gating, suggesting that in heart failure in which Zn2+ levels are elevated, RyR2 channels do not gate in a sub-conductance state, but rather MG23-gating becomes more apparent. We also show that in H9C2 cells exposed to ischemic conditions, intracellular Zn2+ levels are elevated, coinciding with increased MG23 expression. In conclusion, these data suggest that dysregulated Zn2+ homeostasis alters the function of both RyR2 and MG23 and that both ion channels play a key role in diastolic SR Ca2+ leakage.
    Print ISSN: 0021-9258
    Electronic ISSN: 1083-351X
    Topics: Biology , Chemistry and Pharmacology
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