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  • 1
    Electronic Resource
    Electronic Resource
    Weight reduction and salt restriction in hypertension: Effects on blood pressure and intracellular electrolytes (1986)
    Springer
    Journal of molecular medicine 64 (1986), S. 1183-1185 
    Details
    ISSN: 1432-1440
    Keywords: Salt restriction ; Weight reduction ; Hypertension ; Intracellular electrolytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 16 essential hypertensives on a program of energy restriction (800 kcal/day) with and without simultaneous salt restriction, the effects on blood pressure and intracellular Na+ and Ca2+ in red blood cells were studied. A decrease in blood pressure and intracellular free Na+ and Ca2+ was only observed in the cases of simultaneous energy and salt restriction. The beneficial effect of weight reduction in hypertension thus depends on a diminished salt intake and is probably mediated by changes in intracellular free Ca2+.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01728458
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cellular calcium metabolism in primary hypertension (1987)
    Springer
    Journal of molecular medicine 65 (1987), S. 155-160 
    Details
    ISSN: 1432-1440
    Keywords: Hypertension ; Ca2+
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Several disturbances of cellular Ca2+ metabolism have been described in essential hypertension and in the spontaneously hypertensive rat. Possibly the elevation of intracellular free Ca2+ concentration in arterial smooth muscle cells is one important step in the pathogenesis of primary hypertension. In most studies a decreased energy-dependent Ca2+ transport has been proposed as a mechanism. However, disturbances in cellular Ca2+ metabolism, which can be exclusively ascribed to essential hypertension, have not yet been found. The cause of altered cellular Ca2+ transport in primary hypertension may either be a genetically determined defect of membrane transport or a still-unidentified humoral factor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01728224
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Treatment of resistant hypertension by phlebotomy (1985)
    Springer
    Journal of molecular medicine 63 (1985), S. 762-764 
    Details
    ISSN: 1432-1440
    Keywords: Phlebotomy ; Hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 15 essential hypertensives resistant against a standard triple combination of antihypertensive drugs phlebotomy was performed. Mean arterial pressure was lowered from 140.1±12.2 mm Hg to 123.8±14.9 mm Hg after 14 days. No serious side effects were observed. The duration of the hypoptensive effect of phlebotomy was about 4 weeks. Phlebotomy can be used in addition to drug treatment in resistant essential hypertension.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01733828
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    Paper (German National Licenses)
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