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  • 1
    Electronic Resource
    Electronic Resource
    A decadal climate variation in the tropical Atlantic Ocean from thermodynamic air-sea interactions (1997)
    [s.l.] : Nature Publishing Group
    Nature 385 (1997), S. 516-518 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In some respects, the tropical Atlantic Ocean is similar to the tropical Pacific, having, for example, an equatorial cold tongue of sea surface temperature just south of the Equator, and the northeasterly and southeasterly trade winds converging in the Inter-tropical Convergence Zone (ITCZ) north ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/385516a0
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The cause of the fragile relationship between the Pacific El Niño and the Atlantic Niño (2006)
    [s.l.] : Nature Publishing Group
    Nature 443 (2006), S. 324-328 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] El Niño, the most prominent climate fluctuation at seasonal-to-interannual timescales, has long been known to have a remote impact on climate variability in the tropical Atlantic Ocean, but a robust influence is found only in the northern tropical Atlantic region. Fluctuations in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature05053
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Synthesis and characterization of polycarbonates based on bisphenol S by melt transesterification (1997)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 35 (1997), S. 2453-2460 
    Details
    ISSN: 0887-624X
    Keywords: polycarbonate, bisphenol S ; melt transesterification ; diphenyl carbonate ; oxyethylene ; inherent viscosity ; solubility ; tensile strength ; contact angle ; DSC ; TGA ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Several sulfone-containing polycarbonates, having inherent viscosity 0.25-0.30 dL g-1 in N,N-dimethylformamide (DMF), were prepared by melt polycondensation of diphenyl carbonate (DPC) with various aromatic and aliphatic diols, in the presence of zinc acetate as transesterification catalyst. The polycarbonates were examined with IR spectra, inherent viscosity, solubility, tensile strength, contact angle, DSC and TGA. Almost all polymers were soluble in DMF, pyridine, N-methyl pyrrolidinone (NMP), THF, phenol and dimethylsulfoxide (DMSO), partially soluble in nitrobenzene, but insoluble in acetone. Polycarbonate with introduced ether linkages leads to enhanced flexibility and elongation strength. The contact angle of the polycarbonate based on bisphenol S was found in the range 42-80°, smaller than that of polycarbonates based on bisphenol AF and bisphenol A. The wettability of polycarbonate films based on bisphenol S remarkably increased with increasing oxyethylene unit in polymer chain. The smaller values of Td of PC-3-PC-7 than of PC-1 is attributed to the flexible ether linkage. The thermal stability of a brominated aromatic polycarbonate (PC-2) is less than that of the unbrominated one (PC-1). The brominated aromatic polycarbonate (PC-2) has good flame retardency, as indicated by the large limiting oxygen index 56. © 1997 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 35: 2453-2460, 1997
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
  • 4
    Electronic Resource
    Electronic Resource
    Light microscopy of the pineal organ of two primitive lizards, Platyurus platyurus and Hemidactylus frenatus (1983)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 206 (1983), S. 283-288 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1092060306
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    Paper (German National Licenses)
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  • 5
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    Enhanced warming over the global subtropical western boundary currents (2012)
    Nature Publishing Group
    In:  Nature Climate Change, 2 . pp. 161-166.
    Details
    Publication Date: 2019-09-23
    Description: Subtropical western boundary currents are warm, fast-flowing currents that form on the western side of ocean basins. They carry warm tropical water to the mid-latitudes and vent large amounts of heat and moisture to the atmosphere along their paths, affecting atmospheric jet streams and mid-latitude storms, as well as ocean carbon uptake1, 2, 3, 4. The possibility that these highly energetic currents might change under greenhouse-gas forcing has raised significant concerns5, 6, 7, but detecting such changes is challenging owing to limited observations. Here, using reconstructed sea surface temperature datasets and century-long ocean and atmosphere reanalysis products, we find that the post-1900 surface ocean warming rate over the path of these currents is two to three times faster than the global mean surface ocean warming rate. The accelerated warming is associated with a synchronous poleward shift and/or intensification of global subtropical western boundary currents in conjunction with a systematic change in winds over both hemispheres. This enhanced warming may reduce the ability of the oceans to absorb anthropogenic carbon dioxide over these regions. However, uncertainties in detection and attribution of these warming trends remain, pointing to a need for a long-term monitoring network of the global western boundary currents and their extensions.
    Type: Article , PeerReviewed
    Format: text
    Format: text
    DOI: 10.1038/NCLIMATE1353
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    OceanRep: Article in a Scientific Journal - peer-reviewed
  • 6
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    Heteronemin is a novel c-Met/STAT3 inhibitor against advanced prostate cancer cells (2016)
    Wiley-Blackwell
    In: Prostate
    Details
    Publication Date: 2016-07-16
    Description: BACKGROUND Prostate cancer is one of the most prevalent cancers in men worldwide. Aberrant activation of c-Met/signal transducer and activator of transcription-3 (STAT3) signaling is involved in prostate carcinogenesis, underscoring the demand for developing c-Met/STAT3-targeting drugs. Thus, we first utilized virtual screening strategy to identify STAT3-inhibiting marine compound, heteronemin, and then validated the STAT3-inhibiting function of heteronemin in prostate cancer cells. METHODS Human prostate cancer LNCaP, DU145, and PC-3 cell lines were treated with heteronemin for 24 hr, then the cell viability was evaluated by MTT assay. Flow cytometry was performed to analyze the apoptosis in heteronemin-treated cells. Western blot and quantitative real-time PCR were executed to further confirm the c-Met/STAT3 signaling inhibition by heteronemin in DU145 and PC-3 cells. RESULTS In this study, we employed the virtual screening strategy to identify heteronemin, a spongean sesterterpene, as a potential STAT3 inhibitor from Taiwan marine drugs library. Application of heteronemin potently suppressed the viability and anchorage-independent growth of human prostate cancer cells. Besides, heteronemin induced apoptosis in prostate cancer cells by activation of both intrinsic (caspase-9) and extrinsic (caspase-8) apoptotic pathways. By luciferase assay and expression analysis, it was confirmed that heteronemin inhibited the phosphorylation of c-Met/src/STAT3 signaling axis, STAT3-driven luciferase activities and expression of STAT3-regulated genes including Bcl-xL, Bcl-2, and Cyclin D1. Finally, heteronemin effectively antagonized the hepatocyte growth factor (HGF)-stimulated c-Met/STAT3 activation as well as the proliferation and colonies formation in refractory prostate cancer cells. CONCLUSIONS These findings suggest that heteronemin may constitute a novel c-Met/STAT3-targeting agent for prostate cancer. Prostate © 2016 Wiley Periodicals, Inc.
    Print ISSN: 0270-4137
    Electronic ISSN: 1097-0045
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 7
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    Preparation and magnetic properties of CoWO4 nanocrystals (2012)
    Wiley-Blackwell
    Details
    Publication Date: 2012-07-05
    Description: Cobalt tungstate (CoWO 4 ) nanocrystals with an average size of 20–50 nm were synthesized via a template- or surfactant-free hydrothermal route. The crystal structure and morphology of the as-synthesized CoWO 4 sample were characterized by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. Magnetic measurements on the as-synthesized CoWO 4 nanocrystals indicate a Néel temperature ( T N ) of ∼40 K. This lower T N may be a result of the nanostructured particles that reduce the exchange coupling. The new synthetic route presented in this paper has potential applications to fabricate other metal tungstates (MWO 4 ) materials.
    Print ISSN: 0232-1300
    Electronic ISSN: 1521-4079
    Topics: Geosciences , Physics
    Published by Wiley-Blackwell
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