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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 20 (2004), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Our previous data based on an imaging study suggested that, in cat area 17, the representations of cardinal orientations overlap less than the representation of their nearby angles. The purpose of this study was to further investigate the underlying single-cell properties. Optical imaging was performed first to map the cortical regions corresponding to the four principal contours, the two cardinals and the two obliques. The cortical region activated by a principal orientation but not by the +10° or −10° neighbouring angles, namely the area with optically relative independent orientation selectivity (RIOS), was mapped together with the regions that overlapped with the +10° and/or −10° neighbouring angles (non-RIOS). Electrode penetrations were targeted to the RIOS and non-RIOS regions in each of the four orientations. A comparison between the RIOS and the non-RIOS regions documented a significantly higher percentage of cells with the orientation preference of the cardinal orientations in the cardinal RIOS region than that seen in the other regions. Additionally, the difference in the tuning width of cells between the RIOS and non-RIOS in the cardinal region was significantly larger than the difference between the RIOS and non-RIOS in the oblique region. The cells in the cardinal RIOS region were tuned more sharply and the cells in cardinal non-RIOS region more broadly than the oblique RIOS and/or the non-RIOS region, which showed no significant difference. These data strongly suggest the existence of functional segregation in the region corresponding to the cardinal contours.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    International journal of dermatology 43 (2004), S. 0 
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 13-year-old female presented complaining of swelling of the skin and purplish red papules and nodules on her left leg. These lesions had been present from early childhood and had slowly enlarged, increased in number, and become more verrucous. At the age of 8 years, one of the nodules had been excised by laser, but recurrence was noted within a few months. There was occasional pain and bleeding from the lesion. Physical examination revealed a group of several well-circumscribed, hyperkeratotic, blue-red, vascular plaques arranged linearly along the inside aspect of her left lower extremity, ranging in size from 0.5 to 4.0 cm in diameter (〈link href="#f1"〉Fig. 1). Smaller, discrete satellite nodules with a similar appearance were noted in the vicinity.〈figure xml:id="f1"〉1〈mediaResource alt="image" href="urn:x-wiley:00119059:IJD2261:IJD_2261_f1"/〉Blue-red, hyperkeratotic vascular plaques arranged linearly along the left lower extremityHistopathologic examination showed hyperproliferation and hyperkeratosis of the epidermis. The superficial dermis showed multiple, thin-walled, dilated blood-filled spaces (〈link href="#f2"〉Fig. 2). Similar spaces were present in the lower dermis and subcutaneous tissue. A diagnosis of verrucous hemangioma was made.〈figure xml:id="f2"〉2〈mediaResource alt="image" href="urn:x-wiley:00119059:IJD2261:IJD_2261_f2"/〉Dermatohistopathology revealing hyperproliferation and hyperkeratosis of the epidermis, and multiple dilated blood-filled spaces in the dermis and subcutaneous tissue (hematoxylin and eosin, ×20)
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    International journal of dermatology 43 (2004), S. 0 
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
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