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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 20 (2004), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Our previous data based on an imaging study suggested that, in cat area 17, the representations of cardinal orientations overlap less than the representation of their nearby angles. The purpose of this study was to further investigate the underlying single-cell properties. Optical imaging was performed first to map the cortical regions corresponding to the four principal contours, the two cardinals and the two obliques. The cortical region activated by a principal orientation but not by the +10° or −10° neighbouring angles, namely the area with optically relative independent orientation selectivity (RIOS), was mapped together with the regions that overlapped with the +10° and/or −10° neighbouring angles (non-RIOS). Electrode penetrations were targeted to the RIOS and non-RIOS regions in each of the four orientations. A comparison between the RIOS and the non-RIOS regions documented a significantly higher percentage of cells with the orientation preference of the cardinal orientations in the cardinal RIOS region than that seen in the other regions. Additionally, the difference in the tuning width of cells between the RIOS and non-RIOS in the cardinal region was significantly larger than the difference between the RIOS and non-RIOS in the oblique region. The cells in the cardinal RIOS region were tuned more sharply and the cells in cardinal non-RIOS region more broadly than the oblique RIOS and/or the non-RIOS region, which showed no significant difference. These data strongly suggest the existence of functional segregation in the region corresponding to the cardinal contours.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    International journal of dermatology 43 (2004), S. 0 
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    International journal of dermatology 43 (2004), S. 0 
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 13-year-old female presented complaining of swelling of the skin and purplish red papules and nodules on her left leg. These lesions had been present from early childhood and had slowly enlarged, increased in number, and become more verrucous. At the age of 8 years, one of the nodules had been excised by laser, but recurrence was noted within a few months. There was occasional pain and bleeding from the lesion. Physical examination revealed a group of several well-circumscribed, hyperkeratotic, blue-red, vascular plaques arranged linearly along the inside aspect of her left lower extremity, ranging in size from 0.5 to 4.0 cm in diameter (〈link href="#f1"〉Fig. 1). Smaller, discrete satellite nodules with a similar appearance were noted in the vicinity.〈figure xml:id="f1"〉1〈mediaResource alt="image" href="urn:x-wiley:00119059:IJD2261:IJD_2261_f1"/〉Blue-red, hyperkeratotic vascular plaques arranged linearly along the left lower extremityHistopathologic examination showed hyperproliferation and hyperkeratosis of the epidermis. The superficial dermis showed multiple, thin-walled, dilated blood-filled spaces (〈link href="#f2"〉Fig. 2). Similar spaces were present in the lower dermis and subcutaneous tissue. A diagnosis of verrucous hemangioma was made.〈figure xml:id="f2"〉2〈mediaResource alt="image" href="urn:x-wiley:00119059:IJD2261:IJD_2261_f2"/〉Dermatohistopathology revealing hyperproliferation and hyperkeratosis of the epidermis, and multiple dilated blood-filled spaces in the dermis and subcutaneous tissue (hematoxylin and eosin, ×20)
    Type of Medium: Electronic Resource
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  • 4
    Publication Date: 2016-03-29
    Description: Background. To demonstrate the clinical features, diagnosis, and treatment of nonsteroidal anti-inflammatory drug- (NSAID-) induced diaphragm disease (DD). Methods. A literature search between January 1973 and August 2015 was undertaken. The clinical data of patients with NSAID-induced DD were recorded and analyzed. Results. 159 patients were included. The ratio of male to female was 1 : 2.3; the mean age was years. The most common clinical manifestations were gastrointestinal bleeding and obstruction. 121 (84%) patients took traditional NSAIDs. The durations of NSAIDs use ranged from 2 to 300 months. A majority (59.7%) of DD were seen in the small bowel, were seen secondly in the colon (30.2%), and were mainly located in the ileum (57.9%) and right colon (91.7%), respectively. 80% of patients had multiple diaphragms. 41.5% of small bowel DD were diagnosed preoperatively by capsule endoscopy and/or double-balloon enteroscopy, 52.1% at laparotomy. Nearly 75% of patients underwent surgery, endoscopic balloon dilation was performed in 22 patients, and NSAIDs were withdrawn in 53 patients. Conclusions. NSAID-induced DD is relatively rare. The small bowel is most commonly involved. Preoperative diagnosis of small bowel DD is relatively difficult. Discontinuation of the NSAIDs is recommended, surgical resection is the main treatment presently, and endoscopic balloon dilation should be considered as an alternative therapy.
    Print ISSN: 1687-6121
    Electronic ISSN: 1687-630X
    Topics: Medicine
    Published by Hindawi
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  • 5
    Publication Date: 2016-05-27
    Description: A novel enhancement method of global brightness modulation and local contrast enhancement combined with the improved fuzzy set theory is proposed for color image contrast enhancement. The proposed method consists of three stages. Firstly, putting forward nonlinear global brightness mapping model adjusts dynamic range of images for luminance component of color space. Secondly, membership function is established in stages to adjust local contrast of image details nonlinearly based on fuzzy set theory. Finally, the enhanced images are transformed from color space into color space. The experiments further show that the proposed method has the shortest processing time, the highest AIC values, and the least NIQE values among the other four conventional methods. It has excellent effect, which can enhance the global brightness and local contrast, and advance visibility of low illumination images.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
    Published by Hindawi
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  • 6
    Publication Date: 2014-06-23
    Description: To ensure low failure and high reliability of fiber optic current transducers (FOCTs), it is urgent to study methods of condition monitoring and fault diagnosis in FOCT. Faults in FOCT have statistical characteristics. With the analyzing of time domain and frequency domain features in fiber optic current transformers’ measurement data, we establish correspondence between the physical characteristics of key components in transformer and data features and then build diagnostic analysis model based on Allan variance. According to the Allan variance calculation results, we can diagnose fiber optic current transformer’s health state and realize faults location. Experiment results show that diagnostic methods based on Allan variance are accurate and effective to identify fault features.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
    Published by Hindawi
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  • 7
    Publication Date: 2012-10-23
    Description: A two-way coupling algorithm for wave-current interaction is developed and implemented into a nearshore circulation model to investigate the effects of fully wave-current interaction on irregular wave transformation over an elliptic shoal. The wave field is simulated by a spectral wave model WABED, and the wave-induced current is solved by a quasi-three-dimensional model WINCM. The surface roller effects are represented in the formulation of surface stress, and the roller characteristics are solved by a roller evolution model. The proposed two-way coupling algorithm can describe both the generation of wave-induced current and the current-induced wave transformation, which is more physically reasonable than the one-way approaches. The model test with a laboratory experiment shows that wave-induced currents have an important influence on the wave transformation, for example, the wave energy defocusing due to the strong jet-like current along the centerline of the shoal. It is revealed that the accuracy of simulated wave field can be significantly improved by taking into account the two-way wave-current interaction.
    Print ISSN: 1110-757X
    Electronic ISSN: 1687-0042
    Topics: Mathematics
    Published by Hindawi
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  • 8
    Publication Date: 2014-04-29
    Description: The two-body interception problem with an upper-bounded tangent impulse for the interceptor on an elliptic parking orbit to collide with a nonmaneuvering target on a hyperbolic orbit is studied. Firstly, four special initial true anomalies whose velocity vectors are parallel to either of the lines of asymptotes for the target hyperbolic orbit are obtained by using Newton-Raphson method. For different impulse points, the solution-existence ranges of the target true anomaly for any conic transfer are discussed in detail. Then, the time-of-flight equation is solved by the secant method for a single-variable piecewise function about the target true anomaly. Considering the sphere of influence of the Earth and the upper bound on the fuel, all feasible solutions are obtained for different impulse points. Finally, a numerical example is provided to apply the proposed technique for all feasible solutions and the global minimum-time solution with initial coasting time.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
    Published by Hindawi
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  • 9
    Publication Date: 2015-05-29
    Description: Substance P (SP) contributes to bone formation by stimulating the proliferation and differentiation of bone marrow stromal cells (BMSCs); however, the possible involved effect of SP on apoptosis induced by serum deprivation (SD) in BMSCs is unclear. To explore the potential protective effect of SP and its mechanism, we investigated the relationships among SP, apoptosis induced by SD, and Wnt signaling in BMSCs. SP exhibited a protective effect, as indicated by a reduction in the apoptotic rate, nuclear condensation, caspase-3 and caspase-9 activation, and the ratio of Bax/Bcl-2 that was observed after 24 h of SD. This protective effect was blocked by the inhibition of Wnt signaling or antagonism of the NK-1 receptor. Moreover, SP promoted the mRNA and protein expression of Wnt signaling molecules such as β-catenin, p-GSK-3β, c-myc, and cyclin D1 in addition to the nuclear translocation of β-catenin, indicating that active Wnt signaling is involved in SP inhibition of apoptosis. Our results revealed that mediated by the NK-1 receptor, SP exerts an inhibitory effect on serum deprivation induced apoptosis in BMSCs that is related to the activation of canonical Wnt signaling.
    Electronic ISSN: 1687-9678
    Topics: Medicine
    Published by Hindawi
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  • 10
    Publication Date: 2014-12-25
    Description: A biglucoside (BG) was synthesized with glucose and epichlorohydrin as raw materials. The inhibition of BG against montmorillonite swelling was investigated by various methods including montmorillonite linear expansion test, mud ball immersing test, thermogravimetric analysis, and scanning electron microscopy. The results show that the BG has good inhibition ability to the hydration swelling and dispersion of montmorillonite. Under the same condition, the linear expansion ratio of montmorillonite in BG solution is much lower than that of MEG. The particle distribution measurement, thermogravimetric analysis, FT-IR, and scanning electron microscopy results all prove the efficient inhibition of BG.
    Print ISSN: 2090-9063
    Topics: Chemistry and Pharmacology
    Published by Hindawi
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