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  • 1
    Electronic Resource
    Electronic Resource
    Reconstructing the Diversification of α-Esterases: Comparing the Gene Clusters of Drosophila buzzatii and D. melanogaster (2000)
    Springer
    Journal of molecular evolution 51 (2000), S. 149-160 
    Details
    ISSN: 1432-1432
    Keywords: Key words:Drosophila— Gene duplications — Carboxyl/cholinesterases — Phylogeny — Tertiary structure — Evolutionary rates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. A cluster composed of 10 active α-esterase genes and a pseudogene is distributed over 60 kb in the Drosophila melanogaster genome. This paper describes the corresponding cluster in Drosophila buzzatii, whose lineage diverged from that of D. melanogaster when the subgenera Drosophila and Sophophora diverged about 50 Mya. With three exceptions we find that the composition of the cluster is conserved in the two lineages. The location of αE1 in D. melanogaster differs from that of its nearest relative in D. buzzatii, and αE4 has duplicated independently in the two lineages. The nature of these differences indicates that a mechanism exists whereby copies of genes can be placed in opposite orientation and nonadjacent positions within a gene cluster, although this does not seem to be a feature of earlier events in the cluster's evolution. The rates of amino acid change are not significantly different between orthologs, but the rates differ sevenfold among paralogs, indicating that very different selective forces are acting on the genes of the cluster. Mapping of sequence differences onto a model of the tertiary structure of the enzymes indicates that motifs contributing to substrate binding and catalysis have changed radically in the αE4s and suggest that this subgroup of α-esterases may be evolving into a substantially different functional niche.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002390010075
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A large deep freshwater lake beneath the ice of central East Antarctica (1996)
    [s.l.] : Nature Publishing Group
    Nature 381 (1996), S. 684-686 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The satellite ERS-1, launched in 1991, was the first to be specifically programmed for altimetric surveys of large polar ice sheets. An analysis of the initial fast delivery data gave mean surface elevations every 6.7km along the satellite track2. These defined areas of level ice, which roughly ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/381684a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Hoyle on ice (1981)
    [s.l.] : Nature Publishing Group
    Nature 293 (1981), S. 169-170 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN my research-student days, a colleague with literary ambitions threw his draft thesis on nuclear physics out of the window and settled down to write real fiction instead, although without much success. Fred Hoyle, in contrast, has succeeded in producing outstanding work in both astrophysics and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/293169b0
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  • 4
    Electronic Resource
    Electronic Resource
    Contrasts in Vostok core : changes in climate or ice volume? (1985)
    [s.l.] : Nature Publishing Group
    Nature 316 (1985), S. 578-579 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] CORES from the major ice sheets provide fossil samples of the Earth's atmosphere and yield information on past climates and the mechanisms of glaciation. But obtaining such cores has never been easy, and a really long record has proved elusive. Now Soviet engineers have drilled an ice core of high ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/316578a0
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  • 5
    Electronic Resource
    Electronic Resource
    Regime of the Filchner–Ronne ice shelves, Antarctica (1983)
    [s.l.] : Nature Publishing Group
    Nature 302 (1983), S. 582-586 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Seismic, radio-echo, TWERLE balloon and oceanographic data of the Filchner-Ronne ice shelves are analysed. A large thin area in the central Ronne Ice Shelf is found to differ from the morphology of the Ross and Filchner ice shelves. This area is partly filled by basal saline ice, which can be ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/302582a0
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