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  • 1
    Online Resource
    Online Resource
    Oxford :Oxford University Press, Incorporated,
    Keywords: Stochastic processes. ; Finance -- Statistical methods. ; Electronic books.
    Description / Table of Contents: This book uniquely presents the theoretical treatment of random processes in physics and finance, including applications to laser and semiconductor physics, light propagation in scattering media and investment decisions.
    Type of Medium: Online Resource
    Pages: 1 online resource (342 pages)
    Edition: 1st ed.
    ISBN: 9780191513787
    Series Statement: Oxford Finance Series
    DDC: 530.15828
    Language: English
    Note: Intro -- Contents -- A Note from Co-authors -- 1 Review of probability -- 1.1 Meaning of probability -- 1.2 Distribution functions -- 1.3 Stochastic variables -- 1.4 Expectation values for single random variables -- 1.5 Characteristic functions and generating functions -- 1.6 Measures of dispersion -- 1.7 Joint events -- 1.8 Conditional probabilities and Bayes' theorem -- 1.9 Sums of random variables -- 1.10 Fitting of experimental observations -- 1.11 Multivariate normal distributions -- 1.12 The laws of gambling -- 1.13 Appendix A: The Dirac delta function -- 1.14 Appendix B: Solved problems -- 2 What is a random process -- 2.1 Multitime probability description -- 2.2 Conditional probabilities -- 2.3 Stationary, Gaussian and Markovian processes -- 2.4 The Chapman-Kolmogorov condition -- 3 Examples of Markovian processes -- 3.1 The Poisson process -- 3.2 The one dimensional random walk -- 3.3 Gambler's ruin -- 3.4 Diffusion processes and the Einstein relation -- 3.5 Brownian motion -- 3.6 Langevin theory of velocities in Brownian motion -- 3.7 Langevin theory of positions in Brownian motion -- 3.8 Chaos -- 3.9 Appendix A: Roots for the gambler's ruin problem -- 3.10 Appendix B: Gaussian random variables -- 4 Spectral measurement and correlation -- 4.1 Introduction: An approach to the spectrum of a stochastic process -- 4.2 The definitions of the noise spectrum -- 4.3 The Wiener-Khinchine theorem -- 4.4 Noise measurements -- 4.5 Evenness in & -- #969 -- of the noise? -- 4.6 Noise for nonstationary random variables -- 4.7 Appendix A: Complex variable notation -- 5 Thermal noise -- 5.1 Johnson noise -- 5.2 Equipartition -- 5.3 Thermodynamic derivation of Johnson noise -- 5.4 Nyquist's theorem -- 5.5 Nyquist noise and the Einstein relation -- 5.6 Frequency dependent diffusion constant -- 6 Shot noise -- 6.1 Definition of shot noise. , 6.2 Campbell's two theorems -- 6.3 The spectrum of filtered shot noise -- 6.4 Transit time effects -- 6.5 Electromagnetic theory of shot noise -- 6.6 Space charge limiting diode -- 6.7 Rice's generalization of Campbell's theorems -- 7 The fluctuation-dissipation theorem -- 7.1 Summary of ideas and results -- 7.2 Density operator equations -- 7.3 The response function -- 7.4 Equilibrium theorems -- 7.5 Hermiticity and time reversal -- 7.6 Application to a harmonic oscillator -- 7.7 A reservoir of harmonic oscillators -- 8 Generalized Fokker-Planck equation -- 8.1 Objectives -- 8.2 Drift vectors and diffusion coefficients -- 8.3 Average motion of a general random variable -- 8.4 The generalized Fokker-Planck equation -- 8.5 Generation-recombination (birth and death) process -- 8.6 The characteristic function -- 8.7 Path integral average -- 8.8 Linear damping and homogeneous noise -- 8.9 The backward equation -- 8.10 Extension to many variables -- 8.11 Time reversal in the linear case -- 8.12 Doob's theorem -- 8.13 A historical note and summary (M. Lax) -- 8.14 Appendix A: A method of solution of first order PDEs -- 9 Langevin processes -- 9.1 Simplicity of Langevin methods -- 9.2 Proof of delta correlation for Markovian processes -- 9.3 Homogeneous noise with linear damping -- 9.4 Conditional correlations -- 9.5 Generalized characteristic functions -- 9.6 Generalized shot noise -- 9.7 Systems possessing inertia -- 10 Langevin treatment of the Fokker-Planck process -- 10.1 Drift velocity -- 10.2 An example with an exact solution -- 10.3 Langevin equation for a general random variable -- 10.4 Comparison with Ito's calculus lemma -- 10.5 Extending to the multiple dimensional case -- 10.6 Means of products of random variables and noise source -- 11 The rotating wave van del Pol oscillator (RWVP) -- 11.1 Why is the laser line-width so narrow?. , 11.2 An oscillator with purely resistive nonlinearities -- 11.3 The diffusion coefficient -- 11.4 The van der Pol oscillator scaled to canonical form -- 11.5 Phase fluctuations in a resistive oscillator -- 11.6 Amplitude fluctuations -- 11.7 Fokker-Planck equation for RWVP -- 11.8 Eigenfunctions of the Fokker-Planck operator -- 12 Noise in homogeneous semiconductors -- 12.1 Density of states and statistics of free carriers -- 12.2 Conductivity fluctuations -- 12.3 Thermodynamic treatment of carrier fluctuations -- 12.4 General theory of concentration fluctuations -- 12.5 Influence of drift and diffusion on modulation noise -- 13 Random walk of light in turbid media -- 13.1 Introduction -- 13.2 Microscopic statistics in the direction space -- 13.3 The generalized Poisson distribution p[sub(n)](t) -- 13.4 Macroscopic statistics -- 14 Analytical solution of the elastic transport equation -- 14.1 Introduction -- 14.2 Derivation of cumulants to an arbitrarily high order -- 14.3 Gaussian approximation of the distribution function -- 14.4 Improving cumulant solution of the transport equation -- 15 Signal extraction in presence of smoothing and noise -- 15.1 How to deal with ill-posed problems -- 15.2 Solution concepts -- 15.3 Methods of solution -- 15.4 Well-posed stochastic extensions of ill-posed processes -- 15.5 Shaw's improvement of Franklin's algorithm -- 15.6 Statistical regularization -- 15.7 Image restoration -- 16 Stochastic methods in investment decision -- 16.1 Forward contracts -- 16.2 Futures contracts -- 16.3 A variety of futures -- 16.4 A model for stock prices -- 16.5 The Ito's stochastic differential equation -- 16.6 Value of a forward contract on a stock -- 16.7 Black-Scholes differential equation -- 16.8 Discussion -- 16.9 Summary -- 17 Spectral analysis of economic time series -- 17.1 Overview. , 17.2 The Wiener-Khinchine and Wold theorems -- 17.3 Means, correlations and the Karhunen-Loeve theorem -- 17.4 Slepian functions -- 17.5 The discrete prolate spheroidal sequence -- 17.6 Overview of Thomson's procedure -- 17.7 High resolution results -- 17.8 Adaptive weighting -- 17.9 Trend removal and seasonal adjustment -- 17.10 Appendix A: The sampling theorem -- Bibliography -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- Z.
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  • 2
    Online Resource
    Online Resource
    Singapore : Springer Singapore | Singapore : Imprint: Springer
    Keywords: Remote sensing. ; Environmental monitoring. ; Environmental health. ; Epidemiology.
    Description / Table of Contents: Geographical characteristics of Study area -- Datasets and data preparation -- Flooding identification by vegetation index -- Flood identification by Support Vector Machine (SVM) -- Improved support vector machine classifier by Particle filter algorithm -- Flood related parameters affecting waterborne diseases -- Measure of Disease Risk -- Modeling Outbreak Risk based on Back Propagation Neural Network (BPNN) algorithm -- Application of surveillance communicable diseases risk using Expert system -- Conclusions.
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource(XI, 148 p. 55 illus., 38 illus. in color.)
    Edition: 1st ed. 2021.
    ISBN: 9789811582028
    Language: English
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 53 (1988), S. 507-515 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Chinese Astronomy and Astrophysics 17 (1993), S. 362 
    ISSN: 0275-1062
    Keywords: Sun-coronal loop-plasma
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cancer chemotherapy and pharmacology 21 (1988), S. 191-196 
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Carboplatin and iproplatin, two new analogues of cisplatin, appear to have comparable activity in the treatment of advanced ovarian cancer, but minimal nephro- and neurotoxicities. Hyperthermia can potentiate the cytoxicity of cisplatin in vitro and in vivo, but systemic treatment with the combination has proven unsafe in patients. To provide the rationale for an alternative approach, we evaluated the relative degree of additivity between hyperthermia and the three platinum analogues in vitro against a human ovarian adenocarcinoma cell line, UACC-66. All drug and heat treatments were simultaneous for 1 h. Platinum analogue concentrations covered a five-log range from 0.001 to 100 μg/ml and hyperthermia temperatures included 38.5°, 40°, 41.5°, and 43° C. A tumor clonogenic assay was used to quantitate heat-drug interactive effects against the UACC-66 cells, and statistical analysis was performed using the median-effect equation of Chou. When combined with heat, the in vitro concentrations of the three platinum analogues were between 5% and 25% of those required at 37° C to inhibit 50%–70% of the UACC-66 tumor colony-forming units. For each drug when combined with heat, a 3° C incremental increase in temperature (i.e., from 37° C to 40° C or from 40° C to 43° C) was associated with a ten-fold decrease in ID50 drug concentration. We conclude that the synergistic effects of both carboplatin and iproplatin with hyperthermia at all temperatures above 37° C provide a rationale for design of clinical trials in patients with ovarian cancer using these hyperthermia-drug combinations.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Cleavage of amyloid precursor protein (APP) by the β- and γ-secretases generates the amino and carboxy termini, respectively, of the Aβ amyloidogenic peptides Aβ40 and Aβ42—the major constituents of the amyloid plaques in the brain parenchyma of Alzheimer's ...
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Doxorubicin, cisplatin, and cyclophosphamide are the three drugs most commonly used in the treatment of ovarian cancer, but no effect greater than additivity was observed for any combination of these drugs in the present study. Only a few studies have been reported concerning the degree of their additivity or their best order of sequencing. In our in vitro studies, cisplatin in combination with doxorubicin or 4-hydroperoxycyclophosphamide (4HC) was tested against seven human gynecologic tumor-cell lines in different sequences, using a double-agar layer tissue-culture system. Drug interactions with respect to inhibition of tumor clonogenicity were evaluated by isobologram and fractional survival methods. Doxorubicin and 4HC were sequenced simultaneously and at 1, 6 and 24 h after cisplatin, and cisplatin was sequenced at 1, 6 and 24 h after 4HC. The isobolograms constructed for doxorubicin or 4HC plus cisplatin revealed strict additivity between these agents against ovarian cancer clonogenicity. Both doxorubicin and 4HC showed the greatest additivity when used simultaneously and at 1 h vs 6 or 24 h after cisplatin. Although the mechanisms by which these sequencing effects occur are unknown, these studies provide new leads for the design of clinical trials with combinations of these three agents.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0843
    Keywords: Key words Carboplatin ; Ifosfamide ; Doxorubicin ; G-CSF ; Combination regimen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of the addition of G-CSF to carboplatin, ifosfamide and doxorubicin (CIA) at the maximally tolerated dose (MTD) was studied in a phase I clinical trial. Nine patients with incurable solid tumors were treated: six endometrial and epithelial ovarian cancers, one colon cancer with pelvic masses and two unknown primary cancers. The carboplatin dose was calculated using the Calvert formula and administered in a standard 30-min intravenous infusion. The initial carboplatin dose was AUC 4.0 mg/ml per min. Fixed doses of ifosfamide (1.25 g/m2 per day), mesna (1.0 g/m2 per day, and doxorubicin (15 mg/m2 per day) were combined and given as a 4-day continuous intravenous infusion in an attempt to decrease nonhematologic toxicity. The dose-limiting toxicity of CIA was myelosuppression, mainly neutropenia and thrombocytopenia. Nonhematologic toxicities were hemorrhagic cystitis, weakness, fatigue, and nausea and vomiting. The MTD for CIA was established at the first dose level of carboplatin (4.0 mg/ml per min). Following this, G-CSF was added to the regimen in an unsuccessful effort to escalate the carboplatin dose. Free and total carboplatin pharmacokinetics were determined using flameless atomic absorption spectroscopy. There was one complete response and one partial response among eight evaluable patients. Both responding patients had advanced ovarian cancer. We conclude that carboplatin dose intensification beyond an AUC of 4.0 mg/ml per min is not made feasible by the addition of G-CSF to infusional doxorubicin and ifosfamide in patients with advanced gynecologic cancer.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1618-2545
    Keywords: amphotericin B ; Aspergillus fumigatus ; biocell-tracer ; 5-fluorocytosine ; synergistic effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The biocell-tracer system is a microscopical system to measure the growth rate of a single fungal hypha. The synergistic effect of amphotericin B (AMPH) and 5-fluorocytosine (5-FC) on the growth of hyphae ofAspergillus fumigatus was studied by using this system. Although neither 2µg/ml of AMPH nor 250µg/ml of 5-FC alone showed any effect on the hyphal growth, their combination at these concentrations showed a distinct inhibitory activity. The biocell-tracer system is useful for antifungal activity testing in filamentous fungi.
    Type of Medium: Electronic Resource
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  • 10
    Publication Date: 2018-03-26
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Format: application/pdf
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