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  • 1
    Online Resource
    Online Resource
    Baycinar Tibbi Yayincilik ; 2022
    In:  Turkish Journal of Physical Medicine and Rehabilitation Vol. 68, No. 1 ( 2022-03-01), p. 19-29
    In: Turkish Journal of Physical Medicine and Rehabilitation, Baycinar Tibbi Yayincilik, Vol. 68, No. 1 ( 2022-03-01), p. 19-29
    Abstract: Objectives: In this study, we aimed to investigate whether quality of life (QoL) before intensive care unit (ICU) admission could predict ICU mortality in critically ill patients. Patients and methods: Between January 2019 and April 2019, a total of 105 ICU patients (54 males, 51 females; mean age: 58 years; range, 18 to 91 years) from two ICUs of a tertiary care hospital were included in this cross-sectional, prospective study. Pre-admission QoL was measured by the Short Form (SF)-12- Physical Component Scores (PCS) and Mental Component Scores (MCS) and EuroQoL five-dimension, five-level scale (EQ-5D-5L) within 24 h of ICU admission and mortality rates were estimated. Results: The overall mortality rate was 28.5%. Pre-admission QoL was worse in the non-survivors independent from age, sex, socioeconomic and education status, and comorbidities. During the hospitalization, the rate of sepsis and ventilator/hospital-acquired pneumonia were similar among the two groups (p 〉 0.05). Logistic regression analysis adjusted for sex, age, education status, and Acute Physiology and Chronic Health Evaluation II (APACHE II) scores showed that pre-admission functional status as assessed by the SF-12 MCS (odds ratio [OR]: 14,2; 95% confidence interval [CI] : 2.5-79.0), SF-12 PCS (OR: 10.6; 95% CI: 1.8-62.7), and EQ-5D-5L (OR: 8.0; 95% CI: 1.5-44.5) were found to be independently associated with mortality. Conclusion: Worse pre-admission QoL is a strong predictor of mortality in critically ill patients. The SF-12 and EQ-5D-5L scores are both valuable tools for this assessment. Not only the physical status, but also the mental status before ICU admission should be evaluated in terms of QoL to better utilize ICU resources.
    Type of Medium: Online Resource
    ISSN: 2587-1250
    Language: English
    Publisher: Baycinar Tibbi Yayincilik
    Publication Date: 2022
    detail.hit.zdb_id: 2712472-1
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  • 2
    In: Infectious Diseases in Clinical Practice, Ovid Technologies (Wolters Kluwer Health), Vol. 19, No. 2 ( 2011-03), p. 105-110
    Type of Medium: Online Resource
    ISSN: 1056-9103
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2011
    detail.hit.zdb_id: 2062211-9
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  • 3
    Online Resource
    Online Resource
    Wiley ; 2022
    In:  Therapeutic Apheresis and Dialysis Vol. 26, No. 1 ( 2022-02), p. 115-121
    In: Therapeutic Apheresis and Dialysis, Wiley, Vol. 26, No. 1 ( 2022-02), p. 115-121
    Abstract: Our aim was to determine the relationship between the modality of renal replacement therapy and inflammation markers, BP control, and quality of life (QoL). Sixteen hemodialysis, 17 peritoneal dialysis patients, and 27 kidney transplant receivers (KTr) have been included in this study. Short Form‐36 (SF‐36) for the evaluation of QoL and ambulatory BP monitoring were performed on the same day. Erythrocyte sedimentation rate, CRP, IL‐6, and IL‐10 were measured. While the mean IL‐10, IL‐6, and CRP levels were the highest in the dialysis groups, there were no significantly differences any parameters for all groups. QoL was better in the KTr almost as in healthy controls but worse in the dialysis patients. It should be taken into account that hypertension may occur at night even if the daytime BP is normal in KTr.
    Type of Medium: Online Resource
    ISSN: 1744-9979 , 1744-9987
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2010864-3
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  • 4
    Online Resource
    Online Resource
    Elsevier BV ; 2010
    In:  European Journal of Radiology Vol. 75, No. 2 ( 2010-8), p. 245-247
    In: European Journal of Radiology, Elsevier BV, Vol. 75, No. 2 ( 2010-8), p. 245-247
    Type of Medium: Online Resource
    ISSN: 0720-048X
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2010
    detail.hit.zdb_id: 2005350-2
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  • 5
    In: Cancer Investigation, Informa UK Limited, Vol. 39, No. 6-7 ( 2021-08-09), p. 473-481
    Type of Medium: Online Resource
    ISSN: 0735-7907 , 1532-4192
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2043112-0
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  • 6
    In: International Journal of Gynecologic Cancer, BMJ, Vol. 26, No. 8 ( 2016-10), p. 1480-1484
    Abstract: The aim of this study is to evaluate the results of radical surgery in patients with stage IB2 to IIA2 cervical cancer who were operated on at our center between 2002 and 2015. Materials and Methods Forty-seven cases of patients with stage IB2/IIA2 cervical cancer who underwent primary radical surgery between 2002 and 2015 were enrolled in this study. Patients’ files and pathological reports were retrospectively reviewed. Surgical, pathological, and clinical variables were analyzed and their impact on survival period was researched. Disease-free survival and overall survival periods were determined using the Kaplan-Meier test. The P value was considered significant if less than 0.05. Results Type C2 radical hysterectomy with lymphadenectomy (5 pelvic, 42 pelvic and para-aortic) was performed for all of the 47 patients in accordance with the Querleu-Morrow classification. Thirty-three of the cases were stage Ib2 and 14 cases were IIa2. Five years of overall survival was 80%. Recurrence was noted in 10 (7 pelvic, 3 extrapelvic) patients. Adjuvant therapies were needed for 83% of the patients. A univariate analysis was made for all included variables in this research and, other than recurrence, none of them was found to be statistically significant on OS and DFS. Conclusions Although adjuvant therapies are often resorted to, primary radical surgery is also a reasonable treatment option for stage IB2/IIA2 cervical cancer, especially in young premenopausal patients when preserving ovarian functions is desired.
    Type of Medium: Online Resource
    ISSN: 1048-891X , 1525-1438
    Language: English
    Publisher: BMJ
    Publication Date: 2016
    detail.hit.zdb_id: 2009072-9
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  • 7
    In: American Journal of Nephrology, S. Karger AG, Vol. 20, No. 4 ( 2000), p. 319-323
    Abstract: 〈 i 〉 Background/aims: 〈 /i 〉 The aim of this study was to examine a plausible correlation between venous and arterial blood gas values in acidotic patients with chronic uremia or diabetic ketoacidosis (DKA). 〈 i 〉 Methods: 〈 /i 〉 A total of 152 arterial and 152 venous blood samples from uremic patients (n = 100), DKA patients (n = 21) and healthy controls (n = 31) were analyzed for measurements of blood gas and acid-base status. 〈 i 〉 Results: 〈 /i 〉 The means of arterial and venous pH, and arterial and venous HCO 〈 sup 〉 – 〈 /sup 〉 〈 sub 〉 3 〈 /sub 〉 values for the uremic patients were 7.17 ± 0.14, 7.13 ± 0.14, 10.13 ± 4.26 and 11.86 ± 4.23 mmol/l, respectively. The respective mean differences between arterial and venous pH values and arterial and venous HCO 〈 sup 〉 – 〈 /sup 〉 〈 sub 〉 3 〈 /sub 〉 values were 0.04 ± 0.02 and –1.72 ± 0.42 mmol/l, respectively, for these patients. The means of the laboratory findings of DKA patients were arterial pH, 7.15 ± 0.15; venous pH, 7.10 ± 0.15; arterial HCO 〈 sup 〉 – 〈 /sup 〉 〈 sub 〉 3 〈 /sub 〉 , 8.57 ± 5.71 mmol/l and venous HCO 〈 sup 〉 – 〈 /sup 〉 〈 sub 〉 3 〈 /sub 〉 , 10.46 ± 5.73 mmol/l. The respective mean differences between arterial and venous pH and arterial and venous HCO 〈 sup 〉 – 〈 /sup 〉 〈 sub 〉 3 〈 /sub 〉 for this group were calculated to be 0.05 ± 0.01 and –1.88 ± 0.41 mmol/l. In the healthy controls, the means of arterial and venous pH, and arterial and venous HCO 〈 sup 〉 – 〈 /sup 〉 〈 sub 〉 3 〈 /sub 〉 values were 7.39 ± 0.02, 7.34 ± 0.02, 24.91 ± 0.82 and 26.57 ± 0.83 mmol/l, respectively. For the healthy controls the mean differences between the respective values in arterial and venous pH, and arterial and venous HCO 〈 sup 〉 – 〈 /sup 〉 〈 sub 〉 3 〈 /sub 〉 were 0.05 ± 0.01 and –1.66 ± 0.58 mmol/l. Although in healthy controls the correlation between arterial and venous pH values (r 〈 sup 〉 2 〈 /sup 〉 : 0.595) and arterial and venous HCO 〈 sup 〉 – 〈 /sup 〉 〈 sub 〉 3 〈 /sub 〉 values (r 〈 sup 〉 2 〈 /sup 〉 : 0.552) were moderate, these correlations were significantly increased in both the acidotic patient group (r 〈 sup 〉 2 〈 /sup 〉 : 0.979 and 0.990) and the DKA group (r 〈 sup 〉 2 〈 /sup 〉 : 0.989 and 0.995) 〈 i 〉 Conclusion: 〈 /i 〉 A venous blood sample can be used to evaluate the acid-base status in uremic and DKA patients.
    Type of Medium: Online Resource
    ISSN: 0250-8095 , 1421-9670
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2000
    detail.hit.zdb_id: 1468523-1
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  • 8
    Online Resource
    Online Resource
    S. Karger AG ; 2005
    In:  Urologia Internationalis Vol. 74, No. 1 ( 2005), p. 68-73
    In: Urologia Internationalis, S. Karger AG, Vol. 74, No. 1 ( 2005), p. 68-73
    Abstract: 〈 i 〉 Introduction: 〈 /i 〉 We investigated whether CA9 protein could be used as a prognostic tumor marker as well as a diagnostic biomarker in renal clear cell carcinoma. 〈 i 〉 Materials and Methods: 〈 /i 〉 Nephrectomy specimens from 92 patients were used in this study. 80 of these were renal cell carcinomas, 10 adenomas and 2 oncocytomas. Of the renal cell carcinomas, 67 were clear cell carcinomas. Immunohistochemical analysis using CA9 monoclonal antibody (M75) was performed on paraffin-embedded specimens. CA9 staining was correlated with tumor stage, grade, lymph node involvement, distant metastasis and cumulative survival time. 〈 i 〉 Results: 〈 /i 〉 CA9 was present in 91.2% of clear cell carcinomas. Low staining was a poor prognostic factor, and conversely high staining a good prognostic one. CA9 expression was found to be the best prognostic factor when compared with T stage and grade. Even in low-grade and stage tumors, the presence of low expression correlated with lowered survival times. 〈 i 〉 Conclusions: 〈 /i 〉 On the basis of our study, CA9 is a significant molecular marker in renal clear cell carcinomas. Decreased CA9 expression is independently associated with poor survival. CA9 can be used to predict clinical outcome and identify high-risk patients in need for adjuvant immunotherapy and CA9 targeted therapies.
    Type of Medium: Online Resource
    ISSN: 0042-1138 , 1423-0399
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2005
    detail.hit.zdb_id: 1464417-4
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  • 9
    Online Resource
    Online Resource
    S. Karger AG ; 2017
    In:  International Archives of Allergy and Immunology Vol. 173, No. 3 ( 2017), p. 178-182
    In: International Archives of Allergy and Immunology, S. Karger AG, Vol. 173, No. 3 ( 2017), p. 178-182
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 Although it is known that there has been an increase in asthma and allergic diseases among school-aged children, results vary between countries. The aim of this study was to examine trends in the prevalence of these diseases in the city of Adana (south Turkey) over the last 20 years based on the results of 3 cross-sectional studies. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Three cross-sectional surveys were performed 10 years apart in south Turkey. Here, we compare the surveys conducted among children between the ages of 6 and 14 years from 1994, 2004, and 2014. The participants were randomly chosen among children attending participating primary schools in Adana. The questionnaire in the first survey contained almost the same questions as the ISAAC. In the 2 latter surveys, we used the ISAAC questionnaire to investigate the prevalence of asthma and other allergic diseases. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 A total of 2,334 children in 1994, 3,728 children in 2004, and 3,209 children in 2014 were included in the final analysis. The results showed a statistically significant increase in the prevalence of physician-diagnosed allergic diseases across the years, respectively: asthma (5, 4.6, and 8.9%), allergic rhinitis (8.8, 11.4, and 15.6%), and atopic dermatitis (5, 9.9, and 7%). In contrast, the prevalence of parent-reported current wheeze (16.2, 13.2%) decreased in the last 10 years. 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 Our findings were consistent with the increased prevalence of childhood asthma and other allergic diseases. However, this pattern did not occur in respiratory symptoms.
    Type of Medium: Online Resource
    ISSN: 1018-2438 , 1423-0097
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2017
    detail.hit.zdb_id: 1482722-0
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  • 10
    Online Resource
    Online Resource
    S. Karger AG ; 2005
    In:  Medical Principles and Practice Vol. 14, No. 3 ( 2005), p. 189-193
    In: Medical Principles and Practice, S. Karger AG, Vol. 14, No. 3 ( 2005), p. 189-193
    Abstract: 〈 i 〉 Abstract: 〈 /i 〉 The aim of this study was to determine the reference ranges of lymphocyte subsets in serologically HIV-negative healthy adults in Turkey. 〈 i 〉 Materials and Methods: 〈 /i 〉 Blood samples from 220 healthy adults, 105 female and 115 male, collected into tubes containing EDTA were investigated for lymphocyte subsets using flow cytometry. The age range was 18–80 years (44.80 ± 16.69). 〈 i 〉 Results: 〈 /i 〉 The mean percentage and absolute values of the lymphocyte subsets were as follows: CD3: 72.70 ± 8.44%, 1,680 ± 528 cells/µl; CD4: 47.37 ± 9.10%, 1,095 ± 391 cells/µl; CD8: 28.99 ± 5.99%, 669 ± 239 cells/µl; CD19: 10.96 ± 4.44%, 254 ± 122 cells/µl and CD56: 7.03 ± 3.26%, 161 ± 92 cells/µl, respectively. The ratio of CD4/CD8 was 1.68 ± 0.43. There was no statistically significant difference in the percentages and absolute value 〈 i 〉 s 〈 /i 〉 of lymphocyte subsets between the genders (p 〉 0.05). 〈 i 〉 Conclusion: 〈 /i 〉 Immunophenotyping has been used to establish reference values of lymphocyte subsets in normal healthy adults in Turkey.
    Type of Medium: Online Resource
    ISSN: 1011-7571 , 1423-0151
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2005
    detail.hit.zdb_id: 1482963-0
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