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  • 1
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    Online Resource
    Affective and cognitive theory of mind in posttraumatic stress, major depressive, and somatic symptom disorders: Association with childhood trauma
    Wiley ; 2022
    In:  British Journal of Clinical Psychology Vol. 61, No. 3 ( 2022-09), p. 680-700
    Details
    In: British Journal of Clinical Psychology, Wiley, Vol. 61, No. 3 ( 2022-09), p. 680-700
    Abstract: Childhood trauma constitutes a major risk factor for adult psychopathology, including posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and somatic symptom disorder (SSD). One potential mechanism linking childhood trauma to adult psychopathology may be alterations in theory of mind (ToM). Given the lack of transdiagnostic studies on the association between childhood trauma and ToM, further research is needed to elucidate whether and how childhood trauma relates to ToM impairments across and within diagnostic boundaries. Design A cross‐sectional study design was applied. Methods A total of 137 individuals with varying levels of childhood trauma took part in this study, encompassing individuals with PTSD ( n  = 33), MDD ( n  = 33), SSD ( n  = 36), and healthy volunteers (HVs; n  = 35). To assess ToM performance and childhood trauma, the Movie for the Assessment of Social Cognition was administered along with the Childhood Trauma Questionnaire. Results Only individuals with PTSD, but not individuals with MDD or SSD, showed a worse ToM performance compared to HVs. In the whole sample, childhood trauma correlated negatively with ToM performance. Exploratory group‐specific analyses revealed higher levels of childhood trauma to be associated with more excessive ToM errors in individuals with SSD, and notably with an enhanced ToM performance in individuals with MDD. Conclusions Our results indicate associations between childhood trauma and ToM impairments in a large, transdiagnostic sample. Provided replication in future studies, our findings suggest ToM capacities as a promising treatment target for individuals exposed to severe childhood trauma, at least or particularly with a diagnosis of PTSD. Practitioner points Our results suggest that individuals with a history of severe childhood trauma, at least or particularly with a clinical diagnosis of posttraumatic stress disorder, may benefit from therapeutic approaches targeting theory of mind capacities. Our findings indicate that higher levels of childhood trauma may be linked to a specific ‘hypermentalizing’ bias in somatic symptom disorder. Our findings further point towards an association between higher levels of childhood trauma and a heightened – rather than a diminished – sensitivity towards interpersonal cues in major depressive disorder. Provided further confirmatory evidence, our findings may support diagnosis‐specific approaches in ameliorating theory of mind abilities in individuals with different mental disorders and a history of severe childhood trauma.
    Type of Medium: Online Resource
    ISSN: 0144-6657 , 2044-8260
    URL: Issue
    URL: Article
    DOI: 10.1111/bjc.v61.3
    DOI: 10.1111/bjc.12357
    RVK:
    CL 1000
    Language: English
    Publisher: Wiley
    Publication Date: 2022
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  • 2
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    Heartbeat evoked potentials in patients with post-traumatic stress disorder: an unaltered neurobiological regulation system?
    Informa UK Limited ; 2021
    In:  European Journal of Psychotraumatology Vol. 12, No. 1 ( 2021-01-01)
    Details
    In: European Journal of Psychotraumatology, Informa UK Limited, Vol. 12, No. 1 ( 2021-01-01)
    Type of Medium: Online Resource
    ISSN: 2000-8066
    URL: Article
    DOI: 10.1080/20008198.2021.1987686
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2586642-4
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  • 3
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    An eye-tracking study of interpersonal threat sensitivity and adverse childhood experiences in borderline personality disorder
    Springer Science and Business Media LLC ; 2021
    In:  Borderline Personality Disorder and Emotion Dysregulation Vol. 8, No. 1 ( 2021-12)
    Details
    In: Borderline Personality Disorder and Emotion Dysregulation, Springer Science and Business Media LLC, Vol. 8, No. 1 ( 2021-12)
    Abstract: Previous eye-tracking studies provide preliminary evidence for a hypersensitivity to negative, potentially threatening interpersonal cues in borderline personality disorder (BPD). From an etiological point of view, such interpersonal threat hypersensitivity might be explained by a biological vulnerability along with a history of early life adversities. The objective of the current study was to investigate interpersonal threat hypersensitivity and its association with adverse childhood experiences (ACE) in patients with BPD employing eye-tracking technology. Methods We examined a sample of 46 unmedicated, adult female patients with BPD and 25 healthy female volunteers, matched on age and intelligence, with a well-established emotion classification paradigm with angry, fearful, happy, and neutral facial expressions. ACE were assessed retrospectively with the Childhood Trauma Questionnaire. Results Patients as compared to healthy volunteers reflexively directed their gaze more quickly towards the eyes of emotional and neutral faces and did not adapt their fixation patterns according to the facial expression presented. Misclassifying emotional and neutral faces as angry correlated positively with the patients’ self-reported ACE. Conclusions Building on and extending earlier findings, our results are likely to suggest a visual hypervigilance towards the eyes of emotional and neutral facial expressions and a childhood trauma-related anger bias in patients with BPD. Given the lack of a clinical control group, the question whether these findings are specific for BPD has to remain open. Thus, further research is needed to elucidate the specificity of altered visual attention allocation and the role of ACE in anger recognition in patients with BPD.
    Type of Medium: Online Resource
    ISSN: 2051-6673
    URL: Article
    DOI: 10.1186/s40479-020-00141-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
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  • 4
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    Your smile won’t affect me: Association between childhood maternal antipathy and adult neural reward function in a transdiagnostic sample
    Springer Science and Business Media LLC ; 2023
    In:  Translational Psychiatry Vol. 13, No. 1 ( 2023-02-24)
    Details
    In: Translational Psychiatry, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2023-02-24)
    Abstract: Aberrant activation in the ventral striatum (VS) during reward anticipation may be a key mechanism linking adverse childhood experiences (ACE) to transdiagnostic psychopathology. This study aimed to elucidate whether retrospectively reported ACE, specifically maternal antipathy, relate to monetary and social reward anticipation in a transdiagnostic adult sample. A cross-sectional neuroimaging study was conducted in 118 participants with varying levels of ACE, including 25 participants with posttraumatic stress disorder (PTSD), 32 with major depressive disorder (MDD), 29 with somatic symptom disorder (SSD), and 32 healthy volunteers (HVs). Participants underwent functional magnetic resonance imaging during a monetary and social incentive delay task, and completed a self-report measure of ACE, including maternal antipathy. Neural correlates of monetary and social reward anticipation and their association with ACE, particularly maternal antipathy, were analyzed. Participants showed elevated activation in brain regions underlying reward processing, including the VS, only while anticipating social, but not monetary rewards. Participants reporting higher levels of maternal antipathy exhibited reduced activation in the brain reward network, including the VS, only during social, but not monetary reward anticipation. Group affiliation moderated the association between maternal antipathy and VS activation to social reward anticipation, with significant associations found in participants with PTSD and HVs, but not in those with MDD and SSD. Results were not associated with general psychopathology or psychotropic medication use. Childhood maternal antipathy may confer risk for aberrant social reward anticipation in adulthood, and may thus be considered in interventions targeting reward expectations from social interactions.
    Type of Medium: Online Resource
    ISSN: 2158-3188
    URL: Article
    DOI: 10.1038/s41398-023-02364-y
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2609311-X
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  • 5
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    Measuring types and timing of childhood maltreatment: The psychometric properties of the KERF-40+
    Public Library of Science (PLoS) ; 2022
    In:  PLOS ONE Vol. 17, No. 9 ( 2022-9-8), p. e0273931-
    Details
    In: PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 9 ( 2022-9-8), p. e0273931-
    Abstract: Childhood maltreatment, specifically during sensitive developmental periods, is a major risk factor for poor physical and mental health. Despite its enormous clinical relevance, there is still a lack of scales measuring different types, timing, and duration of childhood maltreatment. The current study sought to validate and determine the psychometric properties of the brief German version of the Maltreatment and Abuse Chronology of Exposure (MACE) scale, the KERF-40. The KERF-40 was administered as an interview (i.e., KERF-40-I) to 287 adult participants with and without mental disorders. Based on item response theory, items of the KERF-40-I were assigned to different types of maltreatment, resulting in a scaled version, the KERF-40+. Test-retest reliability was assessed in a small subsample ( n = 14). Convergent and relative predictive validity were measured with correlations of the KERF-40+ and the Childhood Trauma Questionnaire (CTQ) as well as self-report measures of general and trauma-related psychopathology. Rasch analysis and fit statistics yielded a 49-item version, encompassing ten different types of maltreatment. The test-retest reliability of the KERF-40+ was shown to be acceptable to excellent for almost all global and subscale scores (.74 ≤ ρ ≤ 1.00), with the exception of the subscale emotional neglect (ρ = .55). Convergent validity with the CTQ was confirmed for both KERF-40+ global scores (.72 ≤ r ≤ .87) and corresponding subscale scores (.56 ≤ r ≤ .78). Relative predictive validity was reflected by significant small-to-moderate correlations between KERF-40+ global scores and indices of general and trauma-related psychopathology (.24 ≤ r ≤ .45). Taken together, the KERF-40+ appears to be suited for clinicians and researchers interested in retrospectively assessing different types, timing, and duration of childhood maltreatment experiences during sensitive periods in adults.
    Type of Medium: Online Resource
    ISSN: 1932-6203
    URL: Article
    URL: Article
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    DOI: 10.1371/journal.pone.0273931
    DOI: 10.1371/journal.pone.0273931.g001
    DOI: 10.1371/journal.pone.0273931.t001
    DOI: 10.1371/journal.pone.0273931.t002
    DOI: 10.1371/journal.pone.0273931.t003
    DOI: 10.1371/journal.pone.0273931.t004
    DOI: 10.1371/journal.pone.0273931.t005
    DOI: 10.1371/journal.pone.0273931.s001
    DOI: 10.1371/journal.pone.0273931.s002
    DOI: 10.1371/journal.pone.0273931.s003
    DOI: 10.1371/journal.pone.0273931.s004
    Language: English
    Publisher: Public Library of Science (PLoS)
    Publication Date: 2022
    detail.hit.zdb_id: 2267670-3
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  • 6
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    Childhood maltreatment and amygdala response to interpersonal threat in a transdiagnostic adult sample: The role of trait dissociation
    Elsevier BV ; 2024
    In:  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging ( 2024-1)
    Details
    In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, Elsevier BV, ( 2024-1)
    Type of Medium: Online Resource
    ISSN: 2451-9022
    URL: Article
    DOI: 10.1016/j.bpsc.2024.01.003
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2024
    detail.hit.zdb_id: 2879089-3
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  • 7
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    The impact of traumatic childhood experiences on interoception: disregarding one’s own body
    Springer Science and Business Media LLC ; 2023
    In:  Borderline Personality Disorder and Emotion Dysregulation Vol. 10, No. 1 ( 2023-02-15)
    Details
    In: Borderline Personality Disorder and Emotion Dysregulation, Springer Science and Business Media LLC, Vol. 10, No. 1 ( 2023-02-15)
    Abstract: Deficient interoception, the processing and perception of internal bodily signals, has been discussed as a mechanism underlying various mental disorders. First results indicate a mediating role of interoception in the interplay of traumatic childhood experiences and adult mental disorders. Traumatic childhood experiences may hinder the adequate processing, integration, and trust in bodily signals that are important in order to understand and regulate own needs and emotions, thereby increasing the vulnerability for mental disorders. However, an overarching study investigating alterations in different interoceptive measures and trauma-related disorders as well as their mediating role between early trauma and emotion dysregulation is still missing. Methods One hundred thirty-six individuals with varying levels of traumatic childhood experiences who either had a current diagnosis of major depression, posttraumatic stress disorder, or somatic symptom disorder, or no mental disorder, took part in a multidimensional assessment of interoceptive processes, including interoceptive accuracy, sensibility, and awareness. Kruskal–Wallis tests were used to compare groups regarding interoceptive processes and associations with traumatic childhood experiences and emotion dysregulation were analyzed with Spearman correlations. Furthermore, mediation analyses were computed to examine and compare interoceptive processes as potential mediators between traumatic childhood experiences and emotion dysregulation. Results Only body dissociation, a measure for interoceptive sensibility, was significantly reduced in individuals with a current mental disorder. Body dissociation was also the only interoceptive measure significantly associated with traumatic childhood experiences and emotion dysregulation and the only significant mediator in the relationship between traumatic childhood experiences and emotion dysregulation across groups. Conclusion Results suggest body dissociation, but not other interoceptive measures, as an important feature linking traumatic childhood experiences to current emotion dysregulation, an important transdiagnostic feature. As body dissociation refers to a habitual non-attendance or disregard of interoceptive signals, integrative therapeutic interventions could help affected individuals to overcome difficulties in emotion perception and regulation. Trial registration The general study design was preregistered; see the German Clinical Trials Register (DRKS-ID: DRKS00015182). This study’s analysis plan was not preregistered.
    Type of Medium: Online Resource
    ISSN: 2051-6673
    URL: Article
    DOI: 10.1186/s40479-023-00212-5
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
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  • 8
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    A Prospective Study of Mental Health During the COVID‐19 Pandemic in Childhood Trauma–Exposed Individuals: Social Support Matters
    Wiley ; 2021
    In:  Journal of Traumatic Stress Vol. 34, No. 3 ( 2021-06), p. 477-486
    Details
    In: Journal of Traumatic Stress, Wiley, Vol. 34, No. 3 ( 2021-06), p. 477-486
    Abstract: JOTS‐20‐0330.R2_Seitz_Cantonese Traditional Chinese 新冠疫症大流行期間兒童創傷暴露個體心理健康的前瞻性研究: 社會支持問題 摘要: 2019年新型冠狀病毒(COVID‐19)大流行及其前所未有的社會限制可能會對心理健康產生嚴重影響, 特別是對那些經歷過童年創傷經歷(CTE)的臨床治療者。這項前瞻性研究旨在調查與大約1年前收集的大流行前的基線數據相比, 疫症期間一般心理病理學和創傷後壓力症(PTSD)症狀嚴重程度是否增加。此外, 我們還調查了症狀的增加是否與CTE有關, 以及是否由缺乏感知的社會支持和對新冠疫症的恐懼所調解。在德國社會限制最嚴重的時期, 我們對85人進行了在線調查, 包括患有創傷後壓力症、嚴重抑鬱症或軀體症狀障礙的參與者(n = 63)和健康志願者(n = 22)。調查包括《兒童創傷問卷》、《簡易症狀表》、《第五版創傷後壓力症調查表》、《充實社會支持量表》和《新冠疫症恐懼調查表》。在整個樣本中, 我們發現在新冠疫症大流行期間, 一般心理病理學和創傷後壓力症症狀嚴重程度比之前有明顯的增加, ω2=0.07‐0.08, 其中CTE預測創傷後壓力症症狀嚴重程度增加, β=0.245, p=0.042。這一效應是由缺乏感知的社會支持所調解的, 間接效應=0.101, 95%CI[.013, .209] , 但不是對新冠疫症的恐懼, 間接效應=0.060, 95%CI[‐.035, .167]。這些發現強調了促進社會包容的干預措施的重要性, 以減輕針對新冠疫症大流行病實施的公共衛生行動對童年創傷經歷臨床治療者的潛在不利影響。 Simplified Chinese 新冠疫症大流行期间儿童创伤暴露个体心理健康的前瞻性研究: 社会支持问题 摘要: 2019年新型冠状病毒(COVID‐19)大流行及其前所未有的社会限制可能会对心理健康产生严重影响, 特别是对那些经历过童年创伤经历(CTE)的临床治疗者。这项前瞻性研究旨在调查与大约1年前收集的大流行前的基线数据相比, 疫症期间一般心理病理学和创伤后压力症(PTSD)症状严重程度是否增加。此外, 我们还调查了症状的增加是否与CTE有关, 以及是否由缺乏感知的社会支持和对新冠疫症的恐惧所调解。在德国社会限制最严重的时期, 我们对85人进行了在线调查, 包括患有创伤后压力症、严重抑郁症或躯体症状障碍的参与者(n = 63)和健康志愿者(n = 22)。调查包括《儿童创伤问卷》、《简易症状表》、《第五版创伤后压力症调查表》、《充实社会支持量表》和《新冠疫症恐惧调查表》。在整个样本中, 我们发现在新冠疫症大流行期间, 一般心理病理学和创伤后压力症症状严重程度比之前有明显的增加, ω2=0.07‐0.08, 其中CTE预测创伤后压力症症状严重程度增加, β=0.245, p=0.042。这一效应是由缺乏感知的社会支持所调解的, 间接效应=0.101, 95%CI[.013, .209], 但不是对新冠疫症的恐惧, 间接效应=0.060, 95%CI[‐.035, .167] 。这些发现强调了促进社会包容的干预措施的重要性, 以减轻针对新冠疫症大流行病实施的公共卫生行动对童年创伤经历临床治疗者的潜在不利影响。
    Type of Medium: Online Resource
    ISSN: 0894-9867 , 1573-6598
    URL: Issue
    URL: Article
    DOI: 10.1002/jts.v34.3
    DOI: 10.1002/jts.22660
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2017312-X
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  • 9
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    The association between psychopathology, childhood trauma, and emotion processing.
    American Psychological Association (APA) ; 2022
    In:  Psychological Trauma: Theory, Research, Practice, and Policy ( 2022-05-05)
    Details
    In: Psychological Trauma: Theory, Research, Practice, and Policy, American Psychological Association (APA), ( 2022-05-05)
    Type of Medium: Online Resource
    ISSN: 1942-969X , 1942-9681
    URL: Article
    DOI: 10.1037/tra0001261
    Language: English
    Publisher: American Psychological Association (APA)
    Publication Date: 2022
    detail.hit.zdb_id: 2497028-1
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  • 10
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    Negative affect provides a context for increased distrust in the daily lives of individuals with a history of childhood maltreatment
    Wiley ; 2023
    In:  Journal of Traumatic Stress Vol. 36, No. 4 ( 2023-08), p. 808-819
    Details
    In: Journal of Traumatic Stress, Wiley, Vol. 36, No. 4 ( 2023-08), p. 808-819
    Abstract: Evidence on individuals affected by posttraumatic stress disorder (PTSD) following childhood maltreatment (CM) supports cognitive models suggesting that trauma engenders distrust and interpersonal threat sensitivity. We examined the associations between CM and both distrust and interpersonal threat sensitivity in daily life and investigated whether momentary negative affect (NA) provides a context that strengthens this association. Hypotheses were based on cognitive models of trauma and the feelings‐as‐information theory. In a 7‐day ambulatory assessment study with six semirandom daily prompts (2,295 total), we measured self‐reported momentary NA and assessed behavioral trust as well as interpersonal threat sensitivity via facial emotion ratings with two novel experimental paradigms in 61 participants with varying levels of CM (45,900 total trials). As hypothesized, NA was associated with increased momentary distrust, β = .03, p = .002, and interpersonal threat sensitivity, β = −.01, p = .021. Higher levels of CM were associated with more negative emotion ratings, independent of affective context, β = −.07, p = .003. Momentary behavioral distrust was associated with CM at high levels of momentary NA, β = .02, p = .027. The findings for both tasks support the feelings‐as‐information theory and suggest that cognitive alterations surrounding distrust and interpersonal threat, which were originally proposed for PTSD, likely also affect individuals with a history of CM.
    Type of Medium: Online Resource
    ISSN: 0894-9867 , 1573-6598
    URL: Issue
    URL: Article
    DOI: 10.1002/jts.v36.4
    DOI: 10.1002/jts.22951
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2017312-X
    SSG: 2,1
    SSG: 5,2
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