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  • 1
    In: Family Practice, Oxford University Press (OUP), Vol. 38, No. 3 ( 2021-06-17), p. 225-230
    Abstract: Impact of heart disease (HD) on pregnancy is significant. Objective We aimed to evaluate the feasibility of integrating screening echocardiography (echo) into the Brazilian prenatal primary care to assess HD prevalence. Methods Over 13 months, 20 healthcare workers acquired simplified echo protocols, utilizing hand-held machines (GE-VSCAN), in 22 primary care centres. Consecutive pregnant women unaware of HD underwent focused echo, remotely interpreted in USA and Brazil. Major HD was defined as structural valve abnormalities, more than mild valve dysfunction, ventricular systolic dysfunction/hypertrophy, or other major abnormalities. Screen-positive women were referred for standard echo. Results At total, 1 112 women underwent screening. Mean age was 27 ± 8 years, mean gestational age 22 ± 9 weeks. Major HD was found in 100 (9.0%) patients. More than mild mitral regurgitation was observed in 47 (4.2%), tricuspid regurgitation in 11 (1.0%), mild left ventricular dysfunction in 4 (0.4%), left ventricular hypertrophy in 2 (0.2%) and suspected rheumatic heart disease in 36 (3.2%): all, with mitral valve and two with aortic valve (AV) involvement. Other AV disease was observed in 11 (10%). In 56 screen-positive women undergoing standard echo, major HD was confirmed in 45 (80.4%): RHD findings in 12 patients (all with mitral valve and two with AV disease), mitral regurgitation in 40 (14 with morphological changes, 10 suggestive of rheumatic heart disease), other AV disease in two (mild/moderate regurgitation). Conclusions Integration of echo screening into primary prenatal care is feasible in Brazil. However, the low prevalence of severe disease urges further investigations about the effectiveness of the strategy.
    Type of Medium: Online Resource
    ISSN: 1460-2229
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 1484852-1
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  • 2
    In: Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Revista Brasileira de Farmacia Hospitalar e Servicos de Saude, Vol. 13, No. 4 ( 2022-12-23), p. 874-
    Abstract: Objetivo: Avaliar o desempenho de termos trigger tools na detecção de internações de pacientes idosos com potencial delirium hiperativo em uma unidade de emergência. Métodos: Um estudo transversal foi realizado com todos os pacientes com idade ≥ 60 anos internados em unidade de emergência de um hospital universitário brasileiro em 2018. A triagem de potencial delirium hiperativo foi feita com as seguintes trigger tools: prescrição instra-hospitalar de antipsicóticos, códigos do 10° Código Internacional de Doenças (CID-10) proposto pela 5ª edição do Manual Diagnóstico e Estatístico de Transtornos Mentais, e palavras-chave relacionadas com delirium hiperativo registradas em prontuários médicos por profissionais da saúde. O valor preditivo positivo (VPP) foi calculado para avaliar a performance de cada trigger tool. Resultados: A maioria das hospitalizações (192/286) foi triada por pelo menos um dos trigger tools, das quais 49.2% mostrou potencial delirium hiperativo. O trigger tool de CID-10 mostrou uma melhor performance (VPP=0.71), no entanto, essa estratégia subestimou a detecção de casos potenciais [2.6% (5/193)]. A despeito da performance de das prescrições intra-hospitalares de antipsicóticos e palavras-chave ter sido mais baixa (VPP=0.69, e VPP=0.48, respectivamente), a prevalência de potencial delirium hiperativo identificado foi maior com estes métodos [30.0% (58/193); e 47.1% (91/193); respectivamente] . Conclusão: O uso de trigger tools detectou uma a cada três hospitalizações de idosos com potencial delirium hiperativo. A combinação das estratégias pode contribuir para o reconhecimento da síndrome em unidade de emergência. Os dados sugerem que a triagem pode ser realizada por farmacêuticos em associação com abordagens multicomponentes e interprofissionais para melhorar a segurança do paciente.
    Type of Medium: Online Resource
    ISSN: 2316-7750 , 2179-5924
    Language: Unknown
    Publisher: Revista Brasileira de Farmacia Hospitalar e Servicos de Saude
    Publication Date: 2022
    detail.hit.zdb_id: 3101118-4
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  • 3
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 142, No. Suppl_3 ( 2020-11-17)
    Abstract: Introduction: Morbidity and mortality associated with advanced heart disease (HD) is significant in Brazil. Underserved populations often experience long delays in diagnosis, with long waiting lines for echocardiography (echo). We aimed to evaluate the feasibility of integrating screening echocardiography (echo) with remote interpretation in the Brazilian primary care (PC), and to assess HD prevalence. Methods: In 36 months, 25 healthcare workers at 40 PC units were trained on simplified handheld (GE VSCAN) echo protocols. Screening (SC) groups, including patients aged 17-20, 35-40 and 60-65 years, and patients referred (RF) for clinical indications, in waiting lines, answered a clinical questionnaire and underwent focused echo, interpreted in US and Brazil by telemedicine. Significant HD was defined as moderate/severe valve disease, ventricular dysfunction/hypertrophy, pericardial effusion or wall-motion abnormalities. A study-derived score including clinical variables (sex, body mass, hypertension, coronary disease, heart failure, heart surgery, valve disease and Chagas disease: low ( 〈 13%), intermediate (13% - 69%) and high-risk (≥70%)) was applied to predict HD in echo screening. Results: From January 2017 to November 2019, 4425 patients underwent echo; 1338 (30%) in SC group. Mean age was 54±18 years, 63.7% were females; 57.8% had hypertension and 20.1% diabetes. The most frequent symptoms were chest pain (32.3%), dyspnea (32.3%) and palpitations (25.6%). Significant HD was found in 1409 (31.8%) patients, (28.8% in SC vs. 33.2% in RF group, p=0.004). Comparing SC to RF, severe left ventricular dysfunction was observed in 2.6% vs. 3.1%, p=0.45, severe aortic or mitral regurgitation in 1.5% vs. 1.0%, p=0.17. Prevalence was higher in high-risk patients according to the clinical score, compared to intermediate/low risk (45.3% vs. 26.6%, p 〈 0.001). The continuous risk score was strongly associated with HD (odds ratio=25.8, 95% IC 16.5 - 40.4, p 〈 0.001), with area under ROC curve=0.61. Conclusions: Integration of screening echo into PC is feasible in Brazil as a strategy to prioritize cardiovascular care in low income areas through task-shifting. In association with clinical variables, this tool may improve early diagnosis and referrals.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 1466401-X
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