Note: Front Cover -- Molecular Regulation of Nuclear Events in Mitosis and Meiosis -- Copyright Page -- Table of Contents -- Preface -- Chapter 1. Development of Cytoplasmic Activities That Control Chromosome Cycles during Maturation of Amphibian Oocytes -- I. INTRODUCTION -- II. OOCYTE MATURATION -- III. MATURATION-PROMOTING FACTOR (MPF) -- IV. CYTOSTATIC FACTOR (CSF) -- V. CONCLUDING REMARKS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 2. Dynamics of the Nuclear Lamina during Mitosis and Meiosis -- I. INTRODUCTION -- II. DYNAMICS OF THE NUCLEAR LAMINA IN MITOSIS -- III. DYNAMICS OF THE NUCLEAR LAMINA DURING MEIOTIC PROPHASE -- IV. DYNAMICS OF THE NUCLEAR LAMINA DURING EGG MATURATION AND EARLY DEVELOPMENT -- V. COMPARISON OF THE DYNAMICS OF THE NUCLEAR LAMINA DURING MITOSIS AND MEIOSIS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 3. Regulation of Nuclear Formation and Breakdown in Cell-Free Extracts of Amphibian Eggs -- I. INTRODUCTION -- IL REGULATION OF PRONUCLEAR FORMATION -- III. REGULATION OF CHROMOSOME CONDENSATION -- IV. THE ROLE OF MPF, Ca2+ IONS, AND PROTEINPHOSPHORYLATION IN CONTROLLING NUCLEAR ENVELOPE BREAKDOWN, CHROMOSOME CONDENSATION, AND SPINDLE ASSEMBLY IN CELL-FREE EXTRACTS -- V. SUMMARY -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 4. Role of Protein Phosphorylation in Xenopus Oocyte Meiotic Maturation -- I. INTRODUCTION -- II. MATURATION-INHIBITING PHOSPHOPROTEINS (Mp-P) AND cAMP -- III. PROTEIN PHOSPHORYLATION AND MATURATION-PROMOTING FACTOR (MPF) ACTIVITY -- IV. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 5. Maintenance of Oocyte Meiotic Arrest by Follicular Fluid Factors -- I. INTRODUCTION -- II. CHARACTERIZATION OF FOLLICULAR FLUID OOCYTE MATURATION INHIBITOR (OMI) BY USE OF ISOLATED MAMMALIAN OOCYTES. , III. HYPOXANTHINE IN PIG FOLLICULAR FLUID AS THE PRINCIPAL INHIBITOR OF MOUSE OOCYTE MATURATION AND THE PREVENTION OF FOLLICLE STIMULATING HORMONE (FSH) REVERSAL OF cAMP-MAINTAINED MEIOTIC ARREST -- IV. ASSAY FOR AND CHARACTERIZATION OF HUMAN FOLLICULAR FLUID OMI BY USE OF OOCYTES FROM THE AMPHIBIAN , XENOPUS LAEVIS -- V. FAILURE TO INHIBIT XENOPUS OOCYTE MATURATION BY USE OF EXOGENOUS HYPOXANTHINE IN COMBINATION WITH N6,2' -O-DIBUTYRYL-cAMP (Bt2-CYCLIC AMP) -- VI. HOW DO THE INHIBITORY FACTORS PRESENT IN FOLLICULAR FLUID MAINTAIN MEIOTIC ARREST IN OOCYTES? -- VII. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 6. Regulation of Chromatin Condensation and Decondensation in Sea Urchin Pronuclei -- I. INTRODUCTION -- II. MITOTIC AND PREMATURE CHROMOSOME CONDENSATION -- III. MALE PRONUCLEAR DECONDENSATION -- IV. CONCLUSIONS -- ADDENDUM -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 7. Regulation of Mitosis by Nonhistone Protein Factors in Mammalian Cells -- I. INTRODUCTION -- II. THE MITOTIC FACTORS -- III. INHIBITORS OF THE MITOTIC FACTORS -- IV. ROLE OF PROTEIN PHOSPHORYLATION AND DEPHOSPHORYLATION IN THE REGULATION OF NUCLEAR EVENTS ASSOCIATED WITH MITOSIS AND MEIOSIS -- V. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 8. Mitosis-Specific Cytoplasmic Protein Kinases -- I. INTRODUCTION -- II. IDENTIFICATION OF PROTEIN KINASES IN CELLULAR EXTRACTS -- III. CELL CYCLE SPECIFICITY OF KINASE ACTIVITIES -- IV. COMPARISON OF KINASE ACTIVITIES WITH PROTEIN KINASES IMPLICATED IN MITOTIC EVENTS -- V. COMPARISON OF KINASE ACTIVITIES WITH MITOTIC FACTORS -- VI. CONCLUSIONS AND PERSPECTIVES -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 9. Antibodies to Mitosis-Specific Phosphoproteins -- I. INTRODUCTION -- II. MONOCLONAL ANTIBODIES TO CELLS IN MITOSIS -- III. CHARACTERIZATION OF ANTIGENS REACTIVE WITH MPM-1 AND MPM-2. , IV. CYTOLOGICAL LOCALIZATION OF ANTIGENS REACTIVE WITH MPM-1 AND MPM-2 -- V. BIOLOGICAL ACTIVITY OF MPM-1 AND MPM-2 ANTIBODIES -- VI. DISCUSSION -- REFERENCES -- Chapter 10. Mitosis-Specific Protein Phosphorylation Associated with Premature Chromosome Condensation in a ts Cell Cycle Mutant -- I. INTRODUCTION -- II. ISOLATION AND PRELIMINARY CHARACTERIZATIONOF THE tsBN2 CELL LINE -- III. INDUCTION OF PREMATURE CHROMOSOME CONDENSATION (PCC) IN tsBN2 CELLS AT THE NONPERMISSIVE TEMPERATURE -- IV. INDUCTION OF MITOSIS-SPECIFIC PHOSPHORYLATION IN tsBN2 CELLS BY TEMPERATURE SHIFT -- V. NEWLY SYNTHESIZED PROTEIN(S) IN tsBN2 CELLS SHOWING PCC -- VI. DISCUSSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 11. Chromatin Structure and Histone Modifications through Mitosis in Plasmodia of Physarum polycephalum -- I. INTRODUCTION -- II. CHROMATIN STRUCTURE AND ORGANIZATION -- III. CONTROL OF CHROMOSOME CONDENSATION -- IV. CELL CYCLE STUDIES OF HISTONE MODIFICATIONS -- V. HISTONE H1° -- VI. HISTONE H1 KINASES -- VII. DISCUSSION -- ACKNOWLEDGMENTS -- REFERENCES -- Index.