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  • 1
    Electronic Resource
    Electronic Resource
    Nonlinear Geometric Warping of the Mask Image: A New Method for Reducing Misregistration Artifacts in Digital Subtraction Angiography (1998)
    Springer
    CardioVascular & interventional radiology 21 (1998), S. 138-141 
    Details
    ISSN: 1432-086X
    Keywords: Key words: Angiography, technology—Digital subtraction angiography, technology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: Misregistration artifact is the major cause of image degradation in digital subtraction angiography (DSA). The purpose of this study was to evaluate the efficacy of a newly developed nonlinear geometric warping method to reduce misregistration artifact in DSA. Methods: The processing of the images was carried out on a workstation with a fully automatic computerized program. After making differential images with a lapracian filter, 49 regions of interest (ROIs) were set in the image to be processed. Each ROI of the live image scanned the corresponding ROI of the mask image searching for the best position to match itself. Each pixel of the mask image was shifted individually following the data calculated from the shifts of the ROIs. Five radiologists compared the images produced by the conventional parallel shift technique and those processed with this new method in 16 series of cerebral DSA. Results: In 14 of 16 series (88%), more radiologists judged the images processed with the new method to be better in quality. Small arteries near the skull base and veins of low density were clearly visualized in the images processed by the new method. Conclusion: This newly proposed method could be a simple and practical way to automatically reduce misregistration artifacts in DSA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002709900230
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A flexible random allocation program for multi-institutional clinical trials (1994)
    Springer
    Journal of medical systems 18 (1994), S. 39-53 
    Details
    ISSN: 1573-689X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper describes a flexible random allocation program that assigns treatments to patients according to their prognostic factors in multi-institutional clinical trials. The source lists are available in the appendix of this paper. This program is based on Pocock and Simon's minimization method and Zelen's method for institution balancing. The numbers of institutions, treatments, and prognostic factors can be set arbitrarily. The maximum number of institutions, treatments, or prognostic factors that can be accommodated by the program is limited only by the size of the main memory. For example, an IBM-PC with a 640KB main memory can run a program of 1500 institutions, 4 treatments and 20 prognostic factors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00999323
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A visual data analysis system for the medical image processing (1994)
    Springer
    Journal of medical systems 18 (1994), S. 151-157 
    Details
    ISSN: 1573-689X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We developed a visual data analysis system that can easily manage a large volume of medical imaging data. This system can analyze sets of imaging data using general image processing methods, so that various kinds of medical imaging data such as ECG charts, X ray image films, and MRI images, can be processed. The system has a graphical user interface (GUI). A physician who is novice at the system can manipulate the imaging data intuitively by pull down menus, pop up menus and buttons within the window system. The system can run on a standard UNIX workstation which is faster and more powerful than most personal computers. The system needs an X window system/Motif and C compiler. These are standard system programs already available on most UNIX workstations. The source code of the system can be retrieved from our anonymous ftp site via Internet.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00997293
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    A quantitative color recognition measurement system using multimedia computer environment (1995)
    Springer
    Journal of medical systems 19 (1995), S. 475-483 
    Details
    ISSN: 1573-689X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We developed a quantitative measurement system that tests the degree of dysgnosia resulting from Obsessive-Compulsive Disorder (OCD). The system outputs a stimulation word that had been set in advance using the voice output facility of the personal computer, then displays a color chart and waits for input from the subject. When the subject touches the CRT screen or clicks the mouse, the system records the response time and coordinates of input position. There were 30 stimulation words in the system. After 30 measurements of response time and input coordinates, the system outputs a results file that includes each response time and input coordinates. This test is easier and simpler than other psychological tests such as MMPI. The influence of the examiner can be reduced to the minimum with this system because it is a computer-based automatic measurement system. To use the computer system, an examiner can easily standardize the environment of the illumination, etc. Moreover, the system can save labor in testing, and can manage large amounts of data easily using the file management facility.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02260851
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    A general purpose neural network simulator system for medical data processing (1994)
    Springer
    Journal of medical systems 18 (1994), S. 305-314 
    Details
    ISSN: 1573-689X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We developed a general purpose neural network simulator system for medical data processing. This system has a flexible network definition language. Users can define arbitrary hierarchical neural networks using the definition language to analyze medical data that contains some complex patterns. The learning algorithm used in this system is back propagation. Learning curves are displayed on multiple windows. This is a general purpose system, so it can be used for various kinds of medical data processing such as one dimensional signal processing or two dimensional image processing. The system can run on a standard UNIX workstation, which is faster and more powerful than most personal computers. The system needs an X window system/Motif Motif and C compiler. These are standard system programs already available on most UNIX workstations. The source code of the system can be retrieved from our anonymous ftp site via Internet.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00999272
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Role of the suprachiasmatic nuclei of the hypothalamus on diurnal rhythm in cardiac arrhythmias (1986)
    Springer
    Heart and vessels 2 (1986), S. 15-22 
    Details
    ISSN: 1615-2573
    Keywords: Cardiac bradyarrhythmias ; Diurnal rhythm ; Suprachiasmatic nucleus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ambulatory EGG and EEG recordings were recorded under a 14/10-h light-dark illumination schedule using rats. The rats consisted of two groups: a suprachiasmatic (Sch) lesioned group (n=5) and a normal control group (n=5). Bilateral Sch nuclei were lesioned electrically (DC, 2.5 mA, 30 s for each) using a pair of platinum electrodes 0.3 mm in diameter. After recovery from surgery, recordings of ECGs (leads I, II, and III) and EEGs from the cortex and the left dorsal hippocampus were continued for 6 days. Diurnal periodicity in bradyarrhythmia (sinoatrial block, atrioventricular block) and heart rate was analyzed by the least square fit of 24-h cosines. Significant diurnal rhythm was observed in control rats, whereas Sch-lesioned rats showed no significant diurnal rhythm. The integrity of the Sch nuclei, therefore, is necessary for the generation and/or the expression of diurnal periodicity in bradyarrhythmia in rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02060239
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    Paper (German National Licenses)
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