ISSN:
1476-4687
Quelle:
Nature Archives 1869 - 2009
Thema:
Biologie
,
Chemie und Pharmazie
,
Medizin
,
Allgemeine Naturwissenschaft
,
Physik
Notizen:
[Auszug] XPF–ERCC1 endonuclease is required for repair of helix-distorting DNA lesions and cytotoxic DNA interstrand crosslinks. Mild mutations in XPF cause the cancer-prone syndrome xeroderma pigmentosum. A patient presented with a severe XPF mutation leading to profound crosslink sensitivity and ...
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1038/nature05456
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