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1

Digitale Medien

Serum levels of pregnancy specific protein SP-1 in suspected ectopic pregnancy (1981)

Tatra, G. ; Polak, S. ; Nasr, F. ; [weitere]

Springer

Archives of gynecology and obstetrics 230 (1981), S. 293-297

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ISSN: 1432-0711

Schlagwort(e): Schwangerschaftsspezifisches Protein SP-1 ; Tubargravidität ; Enzym-Immunoassay ; Pregnancy specific protein SP-1 ; Tubal pregnancy ; Enzyme immunoassay

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Beschreibung / Inhaltsverzeichnis: Summary Serum pregnancy specific protein (SP-1) levels were measured preoperatively in 26 women with suspected ectopic pregnancy. We used an enzyme immunoassay with a sensitivity of 2 ng/ml. SP-1 was detected in all 23 patients with a tubal pregnancy, but not in three nonpregnant women with ovarian cysts. Tests for urinary HCG with a sensitivity of 1,000 IU/l were negative in seven of 19 patients with an ectopic pregnancy.

Notizen: Zusammenfassung Mit Hilfe des Enzym-Immunoassays Enzygnost-SP-1 wurde die Serumkonzentration von SP-1 bei 26 Frauen, die unter der Verdachtsdiagnose Tubargravidität operiert wurden, praeoperativ bestimmt. Bei allen 23 Patientinnen mit verifizierter Tubargravidität war SP-1 im Serum nachweisbar, während bei drei nicht graviden Frauen mit Ovarialcysten die Werte von SP-1 unter 2 ng/ml lagen. Routinemäßig durchgeführte Schwangerschaftsteste im Harn hingegen waren in sieben von 19 Fällen mit Tubargravidität negativ. Offenbar kann durch die Messung der SP-1 Serumkonzentration bei Fällen mit Verdacht auf Extrauteringravidität die Diagnostik entscheidend verbessert werden.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02199677

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2

Digitale Medien

An analysis of the sequence of part of the right arm of chromosome II of S. cerevisiae reveals new genes encoding an amino-acid permease and a carboxypeptidase (1994)

Nasr, F. ; Bécam, A. -M. ; Grzybowska, E. ; [weitere]

Springer

Current genetics 26 (1994), S. 1-7

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ISSN: 1432-0983

Schlagwort(e): Yeast ; Sequence ; Amino-Acid Permease ; Carboxypeptidase

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Abstract We have analysed two new genes, YBR1007 and YBR1015, discovered during the systematic sequencing of chromosome II of S. cerevisiae. YBR1007 shows strong similarities to amino-acid permeases, in particular the high-affinity proline permeases of S. cerevisiae and A. nidulans. The number and position of the predicted membrane-spanning domains suggest a conserved structure for these proteins, with 12 trans-membrane domains. YBR1015 shows strong similarities to serine carboxypeptidases; all three residues of the “catalytic triad” typical of this family of enzymes are conserved in the YBR1015 protein. In a preliminary functional analysis we have created a null allele of the YBR1015 gene, and shown that it is not essential for cellular viability.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00326297

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3

Digitale Medien

New trend of the use ofmetarhizium anisopliae (metschnikoff) sokorin andverticillium indicum (petch) gams as entomopathogens to the termiteCryptotermes brevis (Walker) (Isoptera, Kalotermitidae) (1997)

Nasr, F. N. ; Moein, S. I. M.

Springer

Journal of pest science 70 (1997), S. 13-16

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ISSN: 1612-4766

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft

Notizen: Abstract Laboratory bioassay of the two fungiMetarbizium anisopliae (Metschnikoff) Sorokin andVerticillium indicum (Petch) Gams was carried out under 26±1 C° and 75±2% R. H. This is the first study on the efficiency of both mycopathogens against the termiteCryptotermes brevis (Walker). Using the highest concentration ofM. anisopliae (43.5 × 105 V.S/ml), percentages of mortality after 4 weeks from treatment of the termiteC. brevis fed on filter paper or wood were 100 and 93.33, respectively. On the same time, the highest concentration of the fungiV. indicum (34.3 × 105 V.S/ml) resulted in the mortality percentages of 83.33 and 70, respectively, fed on filter paper and wood. In general, the data indicated more susceptibility of the termiteC. brevis to the entomopathogenic fungusM. anisopliae than to the fungusV. indicum. M. anisopliae could be considered as a promising potential mycopathogen against the termiteC. brevis. This study, presenting new approach of the alternative dry wood termite control, might be applied in the future.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02009610

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4

Digitale Medien

Artificial antisense RNA regulation of YBR1012 (YBR136w ), an essential gene from Saccharomyces cerevisiae which is important for progression through G1/S (1995)

Nasr, F. ; Bécam, A. -M. ; Slonimski, P. P. ; [weitere]

Springer

Molecular genetics and genomics 249 (1995), S. 51-57

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ISSN: 1617-4623

Schlagwort(e): Antisense RNA ; YBR1012/YBR136w/MEC1/ESR1 ; Saccharomyces cerevisiae ; Flow cytometry ; Cell cycle

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Abstract YBR1012 (YBR136w) is an essential gene from Saccharomyces cerevisiae identified during the systematic sequencing of part of the right arm of chromosome II. We previously constructed a conditional allele of YBR1012 based on antisense RNA, by inserting a small fragment of this gene downstream from the inducible UASGAL10-CYC1 promoter. Several other antisense RNA constructions have since been made and their activity tested. The response of the system appears to be very delicate, as the presence or absence of 13 nucleotides of polylinker in the 300 nucleotide antisense transcript can dramatically modify its effectiveness. The most effective antisense RNA construction was used in flow cytometry studies to investigate the role of ybr1012p. The results show that during the antisense RNA block some 80% of the cells are arrested with their DNA unreplicated, suggesting that Ybr1012p is needed for progression through G1 or early S phase.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00290235

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5

Digitale Medien

II. Yeast Sequencing Reports. The sequence of 29·7 kb from the right arm of chromosome II reveals 13 complete open reading frames, of which ten correspond to new genes (1994)

Bécam, A.-M. ; Cullin, C. ; Grzybowska, E. ; [weitere]

New York, NY [u.a.] : Wiley-Blackwell

Yeast 10 (1994), S. S1

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ISSN: 0749-503X

Schlagwort(e): Saccharomyces cerevisiae ; chromosome II ; genome sequencing ; CIF1 ; ATPsv ; CKS1 ; Life and Medical Sciences ; Genetics

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie

Notizen: We have determined the complete nucleotide sequence of a 29·7 kb segment from the right arm of chromosome II carried by the cosmid α61. The sequence encodes the 3′ region of the IRA1 gene and 13 complete open reading frames, of which ten correspond to new genes and three (CIF1, ATPsv and CKS1) have been sequenced previously. The density of protein coding sequences is particularly high and corresponds to 84% of the total length. Two new genes encode membrane proteins, one of which is particularly large, 273 kDa. In one case (ATPsv), the comparison of our sequence and the published sequence reveals significant differences. The sequence has been deposited in the EMBL data library under the Accession Number X75891.

Zusätzliches Material: 2 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/yea.320100002

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6

Digitale Medien

The sequence of 36·8 kb from the left arm of chromosome XIV reveals 24 complete open reading frames: 18 correspond to new genes, one of which encodes a protein similar to the human myotonic dystrophy kinase (1996)

Nasr, F. ; Becam, A.-M. ; Herbert, C. J.

New York, NY [u.a.] : Wiley-Blackwell

Yeast 12 (1996), S. 169-175

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ISSN: 0749-503X

Schlagwort(e): genome sequencing ; chromosome XIV ; Saccharomyces cerevisiae ; Myotonic Dystrophy Kinase ; Life Sciences ; Life Sciences (general)

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie

Notizen: We have determined the complete nucleotide sequence of a 36·8 kb segment from the left arm of chromosome XIV carried by the cosmid 14-11. The sequence encodes the 5′ coding region of the PSD1 gene, the 3′ coding region of an unknown gene and 24 complete open reading frames, of which 18 correspond to new genes and six (SKO1, SCL41A, YGP1, YCK2, RPC31 and MFA2) have been sequenced previously. Of the 24 new genes, five show significant similarities to sequences present in the databanks. These include elongation factors 2 and the human myotonic dystrophy kinase. The sequence has been deposited in the EMBL databank under the Accession Number X92517.

Zusätzliches Material: 4 Ill.

Materialart: Digitale Medien

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7

Digitale Medien

The sequence of 12·8 kb from the left arm of chromosome XIV reveals a sigma element, a pro-tRNA and six complete open reading frames, one of which encodes a protein similar to the human leukotriene A4 hydrolase (1996)

Nasr, F. ; Bécam, A.-M. ; Herbert, C. J.

New York, NY [u.a.] : Wiley-Blackwell

Yeast 12 (1996), S. 493-499

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ISSN: 0749-503X

Schlagwort(e): Saccharomyces cerevisiae ; genome sequencing ; chromosome XIV ; leukotriene A4 hydrolase ; Life Sciences ; Life Sciences (general)

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie

Notizen: We have determined the nucleotide sequence of a 12·8 kb fragment from the left arm of chromosome XIV carried by the cosmid 14-16d. An analysis of the sequence reveals the presence of a sigma element, a pro-tRNA gene and eight open reading frames, six of which are complete. All of the eight open reading frames correspond to new genes. Of the eight new genes, two show strong similarities to a pair of new genes from chromosome IX, suggesting an ancestral duplication, and one gene encodes a protein similar to mammalian leukotriene A4 hydrolase. The sequence has been deposited in the EMBL data bank under the Accession Number X94547.

Zusätzliches Material: 6 Ill.

Materialart: Digitale Medien

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8

Unbekannt

eIF4F suppression in breast cancer affects maintenance and progression (2013)

Z Nasr; F Robert; J A Porco; W J Muller; J Pelletier

Nature Publishing Group (NPG)

In: Oncogene

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Publikationsdatum: 2013-02-15

Beschreibung: eIF4F suppression in breast cancer affects maintenance and progression Oncogene 32, 861 (14 February 2013). doi:10.1038/onc.2012.105 Authors: Z Nasr, F Robert, J A Porco, W J Muller & J Pelletier

Schlagwort(e): eIF4EeIF4APyMT mouse modelbreast cancerpulmonary metastasis

Print ISSN: 0950-9232

Thema: Medizin

Publiziert von Nature Publishing Group (NPG)

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