In:
PLOS Neglected Tropical Diseases, Public Library of Science (PLoS), Vol. 15, No. 10 ( 2021-10-19), p. e0009754-
Abstract:
Brazil presents one of the highest COVID-19 death tolls in the world. The initial SARS-CoV-2 epicenter was São Paulo city. As of 2019, the homeless population of São Paulo city was estimated at 24,344 individuals, the largest national homeless population. The present study aimed to concomitantly assess the molecular and serological prevalence and associated risk factors of SARS-CoV-2 infection in a homeless population and related shelter workers from a day-shelter. Serum samples, nasopharyngeal and oropharyngeal swabs of persons who are homeless and shelter workers collected from August 25 th to 27 th , 2020 were tested for the presence of anti-SARS-CoV-2 IgM and IgG antibodies by ELISA and SARS-CoV-2 RNA by RT-qPCR, respectively. All swab samples tested negative by RT-qPCR. Seropositivity of IgM and IgG was 5/203 (2.5%) and 111/203 (54.7%) in persons who are homeless, and 5/87 (5.7%) and 41/87 (47.1%) in shelter workers, respectively, with no statistical differences between groups. The high seroprevalence found herein indicates early environmental and urban spreading of SARS-CoV-2, associated with sociodemographic and economic vulnerability.
Type of Medium:
Online Resource
ISSN:
1935-2735
DOI:
10.1371/journal.pntd.0009754
DOI:
10.1371/journal.pntd.0009754.g001
DOI:
10.1371/journal.pntd.0009754.g002
DOI:
10.1371/journal.pntd.0009754.g003
DOI:
10.1371/journal.pntd.0009754.t001
DOI:
10.1371/journal.pntd.0009754.t002
DOI:
10.1371/journal.pntd.0009754.t003
DOI:
10.1371/journal.pntd.0009754.t004
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2429704-5
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