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  • 1
    Electronic Resource
    Electronic Resource
    Trypsin activity (1994)
    Springer
    Digestive diseases and sciences 39 (1994), S. 2634-2638 
    Details
    ISSN: 1573-2568
    Keywords: acute pancreatitis ; alcohol ; trypsin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A normal serum amylase level is found in up to 32% of patients with acute alcoholic pancreatitis. This underlines the need for more sensitive diagnostic tests in this frequent cause of pancreatitis. Animal and human studies have shown that chronic alcohol consumption leads to important modifications in trypsinogen metabolism. The present work has prospectively analyzed admission serum trypsin activity with a new biochemical test and usual markers such as amylase, lipase, and immunoreactive trypsin in 32 attacks of acute pancreatitis. Seventeen were due to alcohol and 15 to other causes, including 11 with gallstone pancreatitis. High trypsin activity (median: 235 units/liter; range: 165–853) was found in all patients with acute alcoholic pancreatitis even when the amylase level was normal on admission (3/17: 18%). Trypsin activity did not differ between nonalcoholic pancreatitis (N=15): 84 units/liter (42–98), alcoholic controls (N=15): 77 units/liter (40–122), and healthy controls (N=62): 81 units/liter (15–143). The difference was not related to the severity of disease or circulating α2-macroglobulin, α1-protease inhibitor, or immunoreactive trypsinogen levels. Lipase/amylase ratio was less discriminant than trypsin activity between alcoholic and nonalcoholic diseases. We conclude that serum trypsin activity seems specific to acute alcoholic pancreatitis and should be included in new prospective studies assessing biochemical testing of alcohol-related pancreatic diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02087701
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    Paper (German National Licenses)
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  • 2
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    Unknown
    From the northern ice shield to the Alpine glaciations (2012)
    Geozon Science Media
    Details
    Publication Date: 2021-03-29
    Description: The route of the field trip described in this excursion guide follows a section through Germany from North to South, from the area of the Northern glaciation, to the Alpine glacial advances. It includes several places of historical importance, where milestones in Quaternary research have been achieved in the past, as well as new interesting sites where results of recent research is presented.
    Description: excursionguide
    Keywords: 551 ; V 000 ; VCA 520 ; Geologische Wissenschaften ; Quartärgeologie ; coastal evolution; Rügen ; Geopark Mecklenburg Ice Age Landscape ; tourism ; quaternary ; Halle ; Main ; sedimentology ; landslide ; natural hazards ; danube ; rhine ; pleistocene ; holocene ; geology
    Language: English
    Type: anthology , publishedVersion
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    CITATION GEO-LEO
  • 3
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    Millennial-timescale quantitative estimates of climate dynamics in central Europe from earthworm calcite granules in loess deposits (2022)
    Nature Research
    Details
    Publication Date: 2024-02-07
    Description: Ice core and marine archives provide detailed quantitative records of last glacial climate changes, whereas comparable terrestrial records from the mid-latitudes remain scarce. Here we quantify warm season land-surface temperatures and precipitation over millennial timescales for central Europe for the period spanning 45,000–22,000 years before present that derive from two temporally overlapping loess-palaeosol-sequences, dated at high resolution by radiocarbon on earthworm calcite granules. Interstadial temperatures were 1–4 °C warmer than stadial climate, a temperature difference which is strongly attenuated compared to Greenland records. We show that climate in the Rhine Valley was significantly cooler during the warm season and overall drier with annual precipitation values reduced by up to 70% compared to the present day. We combine quantitative estimates with mesoscale wind and moisture transport modelling demonstrating that this region was dominated by westerlies and thereby inextricably linked to North Atlantic climate forcing, although ameliorated.
    Type: Article , PeerReviewed
    Format: text
    Format: text
    Format: other
    Format: other
    Format: other
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    OceanRep: Article in a Scientific Journal - peer-reviewed
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