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  • 1
    Book
    Book
    The geology of North America; Vol. C-1: Geology of the precambrian superior and Grenville provinces and precambrian fossils in North America / co-ordinated by S. B. Lucas ..., [Plates] (1998)
    [Ottawa [u.a.]] : [Geological Survey of Canada]
    Associated volumes
    Details Availability
    In: Vol. C-1, [Plates]
    Type of Medium: Book
    Pages: 10 lose Kt
    ISBN: 0660131358
    Series Statement: Geology of Canada 7
    Language: English
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  • 2
    Book
    Book
    The geology of North America; Vol. C-1: Geology of the precambrian superior and Grenville provinces and precambrian fossils in North America / co-ordinated by S. B. Lucas ..., [Hauptbd.] (1998)
    Ottawa [u.a.] : Geological Survey of Canada
    Associated volumes
    Details Availability
    In: Vol. C-1, [Hauptbd.]
    Type of Medium: Book
    Pages: 387 S , Ill., graph. Darst., Kt
    ISBN: 0660131358
    Series Statement: Geology of Canada 7
    Language: English
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  • 3
    Electronic Resource
    Electronic Resource
    On the Weston Cell (1904)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 8 (1904), S. 196-207 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j150057a002
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  • 4
    Electronic Resource
    Electronic Resource
    Evolution of regional metamorphism in the Cape Smith Thrust Belt (northern Quebec, Canada): interaction of tectonic and thermal processes (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of metamorphic geology 9 (1991), S. 0 
    Details
    ISSN: 1525-1314
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Abstract Syn-metamorphic re-imbrication of the internal part of thrust belts can result in distinct pressure–temperature–time–deformation (P–T–t–d) pathways for different structural–metamorphic domains. In the early Proterozoic Cape Smith Thrust Belt (Canada), an external (piggyback-sequence thrusting) domain is characterized by thermal peak metamorphism occurring after deformation. In contrast, thermal peak metamorphism in an internal domain occurred during re-imbrication by out-of-sequence thrusting. The interactions of tectonic and thermal processes have been studied using three methods: (i) qualitative evaluation of the timing between mineral growth and deformation; (ii) analytical P–T paths from growth-zoned garnet porphyroblasts; and (iii) numerical modelling of vertical heat conduction. Derived P–T–t–d pathways suggest that uplift in the external domain resulted in part from erosion and isostatic unloading. In contrast, paths for the internal domain indicate that the out-of-sequence portion of the thrust belt may have experienced faster unroofing relative to the external domain. This is attributed to thickening by out-of-sequence thrusting and possibly to extensional faulting at (now eroded) higher structural levels. Observations on the timing of metamorphism, coupled with numerical modelling, suggest that the thermal peak metamorphism documented in the external domain is a consequence of the emplacement of the out-of-sequence thrusts stack in the internal portion of the thrust belt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1525-1314.1991.tb00545.x
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  • 5
    Electronic Resource
    Electronic Resource
    Large-scale fluid infiltration, metasomatism and re-equilibration of Archaean basement granulites during Palaeoproterozoic thrust belt construction, Ungava Orogen, Canada (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of metamorphic geology 13 (1995), S. 0 
    Details
    ISSN: 1525-1314
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Abstract The metamorphic history of the Archaean Superior Province crystalline basement in the Palaeoproterozoic Ungava Orogen attests to the importance of structural and geohydrological controls on a retrograde amphibolite-granulite transition. Two distinct metamorphic suites, separated in age by nearly one billion years, are recognized in extensively exposed tonalitic to dioritic metaplutonic gneisses. The older suite comprises c. 2.7-Ga granulite facies assemblages (orthopyroxene-clinopyroxene-hornblende-plagioclase-ilmenite ± biotite ± quartz) that record moderate pressures (±5 kbar) and high temperatures (±800° C). A younger, c. 1.8-Ga suite resulted from amphibolitization of the granulites and is characterized by regionally extensive amphibolite facies mineral zones that broadly parallel the basal décollement of the overlying Proterozoic Cape Smith Thrust Belt. Deformation/mineral growth relationships in the amphibolitized basement indicate that extensive hydration and re-equilibration of the Archaean granulites occurred during thrust belt deformation. The transition from granulite facies to amphibolite facies assemblages is characterized by the growth of garnet-hornblende-quartz ° Cummingtonite coronas between plagioclase and orthopyroxene-clinopyroxene, as well as titanite coronas on ilmenite. Multi-equilibrium thermobarometry on the coronitic assemblages documents re-equilibration of the granulitic gneiss to 7.7 kbar at 644° C in the south and 9.8 kbar at 700° C in the north. The variably deformed, amphibolite facies domain sandwiched between the coronitic garnet zone and the basal décollement is marked by significant metasomatic changes in major element concentrations within tonalite. These changes are compatible with equilibrium flow of an aqueous-chloride fluid down a temperature gradient. The source of fluids for basement hydration/metasomatism is interpreted to be dehydrating clastic rocks in the overlying thrust belt, with fluid flow probably focused along the basal décollement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1525-1314.1995.tb00238.x
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  • 6
    Electronic Resource
    Electronic Resource
    Helicobacter pylori clearance in the treatment of non-ulcer dyspepsia (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 6 (1992), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: One hundred and thirty north Nigerian patients with non-ulcer dyspepsia were treated with tripotassium dicitrato bismuthate and amoxycillin, or antacid. Symptoms resolved in 28 (33%) of bismuth and amoxycillin recipients completing the trial compared with 1 (4%) of the antacid recipients. Symptomatic improvement did not relate to clearance of Helicobacter pylori.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.1992.tb00552.x
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  • 7
    Electronic Resource
    Electronic Resource
    Splenic marginal zone atrophy and progressive CD8+ T-cell lymphocytosis in HIV infection: a study of adult post-mortem spleens from Côte d'Ivoire (2003)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 42 (2003), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims:  Progressive changes have been reported in lymph nodes in HIV infection, but few accounts describe altered splenic histology at different stages of the disease. Investigation of splenic changes accompanying the progressive CD4+ T-cell depletion that occurs in HIV infection could shed light on normal immunological interactions in this organ. Therefore, we assessed the amount and distribution of lymphoid tissue in spleens from adults with documented early or advanced HIV disease.Methods and results:  Immunohistochemistry was used to study splenic tissue collected in an extensive autopsy survey of HIV+ adults in West Africa. Compared with post-mortem spleens from HIV– West African adults and control UK spleens, those from HIV-infected patients showed severe atrophy of white pulp B- and T-cell compartments. In early and advanced HIV disease, marginal zone atrophy was significant. Peri-arteriolar lymphoid sheaths contained increased numbers of CD8+/CD45RO+ T-cells in advanced HIV disease. In red pulp, early and advanced cases showed a lymphocytosis of CD8+/CD45RO– T-lymphocytes.Conclusions:  Atrophic changes were more extreme in advanced than early HIV infection. Reduced marginal zone function possibly explains the known predisposition of HIV+ patients to infection by encapsulated bacteria. Possible immunological consequences of these CD8+/CD45RO+ (peri-arteriolar lymphoid sheaths) and CD8+/CD45RO– (red pulp) responses deserve further study. Comparison of West African and UK control spleens indicated that there were no major ethnic differences in spleen structure to prevent extrapolation of our results to European adults.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2559.2003.01569.x
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  • 8
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of high-dose cyclophosphamide in patients with metastatic bronchogenic carcinoma (1983)
    Springer
    Cancer chemotherapy and pharmacology 11 (1983), S. 196-199 
    Details
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cyclophosphamide (CP) was administered to eight patients with metastatic bronchial carcinoma in escalating doses of 1.5, 2.5, and 3.5 g/m2 at intervals of 3 weeks. The proportion of the administered dose converted into alkylating metabolites was similar for each dose and there was no evidence to suggest that the enzyme system responsible for activating CP was saturated even with the highest dose. Considerable between-patient variation in drug metabolism was observed, but within each patient the fraction metabolised remained constant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00254204
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  • 9
    Electronic Resource
    Electronic Resource
    Deep seismic profile across a Proterozoic collision zone: surprises at depth (1993)
    [s.l.] : Nature Publishing Group
    Nature 363 (1993), S. 339-342 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The Trans-Hudson orogen (THO) forms part of a worldwide network of Proterozoic orogens that weld together Archaean provinces, and formed the connective tissue of a Proterozoic supercontinent9'13. In the study area, the THO is distinguished by the largest exposure of juvenile, arc-derived ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/363339a0
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  • 10
    Electronic Resource
    Electronic Resource
    Distribution of measles virus in the central nervous system of HIV-seropositive children (1998)
    Springer
    Acta neuropathologica 96 (1998), S. 637-642 
    Details
    ISSN: 1432-0533
    Keywords: Key words HIV ;  Measles ; Central nervous system ; Opportunistic infections
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In an autopsy study the distribution of measles virus (MV) in the central nervous system (CNS) of 18 measles-infected children (13 HIV seropositive, 5 HIV seronegative), in Abidjan, Ivory Coast was examined using immunocytochemistry and in situ hybridization. Of these children 17 died from measles giant cell pneumonia. In 3 of the 13 HIV-seropositive patients MV antigens and genomic RNA was detected in the CNS. One of these positive patients had an MV encephalitis with abundant virus throughout most of the CNS. MV was not detected in the CNS of any of the 5 HIV-seronegative patients. These findings, albeit in a small number of cases, would suggest there may be an increased susceptibility to infection of the CNS with MV in HIV-positive children. In this respect entry and growth of MV in the CNS in HIV-seropositive individuals may be similar to the occurrence of measles inclusion body encephalitis in immunocompromised individuals. Furthermore, comparison of the HIV-MV encephalitis patient with two patients with subacute sclerosing panencephalitis (SSPE) demonstrated a paucity of virus in neuronal processes in the HIV-MV encephalitis. Unlike in SSPE, MV maturation by budding through the plasma membrane may occur, thereby minimizing build up of and intracellular movement of incomplete virus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050945
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