ISSN:
1572-879X
Keywords:
microwave irradiation
;
basic catalysis
;
propargylation
;
magnesium oxide
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The alkylation of imidazole (C3H4N2) with propargyl bromide (C3H3Br) using some magnesium oxides as catalysts under microwave irradiation was carried out with a high activity and selectivity. It has been found that it is possible to prepare efficiently N-alkyl derivatives of heterocycles under microwave irradiation in absence of solvent. Under these experimental conditions N-alkylated heterocycles can be obtained with higher selectivities than when using other basic media.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00816318
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