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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of chemical & engineering data 15 (1970), S. 510-513 
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1540-8191
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: The incidence of coronary artery bypass surgery has been increasing annually with increasing pressure on the health care system. Fast track has been proposed as a means to increase efficiency and volume, without an increase in hospital re-sources. To date this approach has not been critically assessed in Canada. Methods: We examined 617 consecutive patients undergoing isolated CABG surgery. The patients were divided into (1) fast track (FT) recovery (n = 219), without admission to an ICU, and (2) nonfast track (NFT) recovery (n = 398) with direct admission to the ICU. There were no differances in age, gender, timing of surgery, left main stenosis, preoperative myocardial infarction, renal failure, diabetes, peripheral vascular disease, or in the incidence of chronic obstructive pulmonary disease between the two groups. The NFT group had a higher proportion of patients with NYHA Class III/IV symptoms preoperatively (65.7% vs. 57.3%, p = 0.048), in patients with an ejection fraction 〈 40% (42.5% vs. 30.6%, p = 0.004), or in the number of individuals with an IABP inserted before surgery (13 vs. 1, p 〈 0.001). Results: In the FT group the average period of aortic occlusion (40.7 ± 15.2 min vs. 71.8 ± 26.5 min, p 〈 0.001) and perfusion time (67.8 ± 24.5 min vs. 117.5 ± 40.2 min, p 〈 0.001) were significantly less than in the NFT group. The number of grafts per patient was 3.3 ± 1.0 vs. 3.2 ± 1.0, respectively (p = 0.38). Operative mortality was 0.9% in the FT group and 1.3% in the NFT group (p = 1.0). Significant differences were seen in the proportion of patients that suffered from postoperative ventilatory failure (3.2% in FT vs. 12.1% in NFT, p 〈 0.001), and the proportion of patients that suffered any postoperative complication was significantly higher in the NFT group (21.4%) than in the FT group (9.1%, p 〈 0.001). The differences in postoporative complications resulted in a shorter length of stay (LOS) in FT patients (5.6 ± 4.1 days vs. 9.7 ± 9.4 days NFT, p 〈 0.001). Only 4.1% of patients that entered the FT group failed and required admission to the ICU. Multivariate stepwise logistic regression analysis identified non-fast track recovery as an independent predictor of morbidity in CABG surgery patients. Conclusions: The data indicate it is possible to perform isolated CABG surgery, in a large proportion of the population, without the need for admission to an ICU for postoperative care.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Pacing and clinical electrophysiology 22 (1999), S. 0 
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Entre 1972 et 1976, 140 malades ont subi un remplacement de valve aortique avec une prothèse de Lillehei-Kaster (LK) et 18 autres un remplacement valvulaire aortique combiné à un bypass coronaire: 98% des cas ont été suivis. La mortalité postopératoire est de 7.5%. La survie actuarielle à 5 ans est de 79%. Il y a eu 2 épisodes de thrombo-embolie sur 3,645 mois/malades. Il n'y a eu ni malfonction de la prothèse, ni hémolyse significative. Le cathétérisme postopératoire montre une surface fonctionnelle de la valve de 0.81 cm2 pour les prothèses 14A et de 1.1 cm2 pour les autres valves. Nous recommandons l'emploi de valves aortiques LK de tailles supérieures à 14A avec anticoagulation par warfarine.
    Notes: Abstract From 1972 through 1976, 140 patients underwent aortic valve replacement (AVR) with the Lillehei-Kaster (LK) prosthesis and 18 additional patients had AVR plus coronary bypass procedures. Follow- up information was obtained in 98% of the patients. The operative mortality rate was 7.5% and the actuarial 5- year survival rate was, 79%. Two episodes of thromboembolism occurred in 3,645 patient-months. Prosthesis malfunction or significant hemolysis has not occurred. Postoperative catheterization studies revealed a functional valve area of 0.81 cm2 with the 14A prosthesis; all other valve areas were greater than 1.1 cm2. Continued use of the LK aortic valve prosthesis with warfarin anticoagulation is recommended in sizes greater than 14A.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pneumopericardium occurred in 28 neonates with respiratory distress syndrome at the University of Minnesota Hospitals and St. Paul Children's Hospital from July 1, 1972 through June 30, 1976. All patients developed this complication while on mechanical ventilatory support with positive end-expiratory pressure (2–12 cm water). In 23 patients, pneumopericardium resulted in clinical pericardial tamponade that necessitated cardiac resuscitation. The clinical presentation of pericardial tamponade consisted of muffled, distant heart sounds, hypotension, bradycardia, and hypoxia with cyanosis. The diagnosis was confirmed by chest x-ray. Pneumothorax, pneumomediastinum, and/or pneumoperitoneum were associated with the appearance of pneumopericardium in 93% of the cases. Treatment consisted of: (a) needle pericardial aspiration in 7 patients, of which 5 survived; (b) pericardial tube placement with application of suction in 10 patients, of which 8 survived; (c) no treatment in 16 patients, of which 5 survived. Overall, 13 patients (46%) survived pneumopericardium and 15 patients (54%) died. Complications of treatment developed in 5 patients; 3 developed pneumothorax and 2 developed myocardial lacerations from percutaneous placement of a plastic drainage catheter. Of 5 asymptomatic patients, 2 (40%) died as a result of pneumopericardium. Based on our experience, it is recommended that pneumopericardium be evacuated whenever it is diagnosed. Initially, needle aspiration of the pericardial sac should be performed to manage the acute episode and stabilize the patient, and then a chest catheter of No. 10 Fr. caliber should be placed under direct vision into the pericardial sac and maintained on suction until positive end-expiratory pressure ventilation has been discontinued.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The hominoid partial skull and several postcranial elements (to be described elsewhere) were discovered at locality 12 (40° 15' 02" N, 32° 38' 58" E) on the southernmost hilltop of Deli-kaymcak Tepe, a prominent ridge located about 2.5 km north of the village of Yassioren. Fossils have been ...
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  • 7
    ISSN: 1573-5028
    Keywords: copper detoxification ; metallothionein ; metal tolerance ; pea ; Pisum sativum ; PsMT A
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The PsMT A gene from pea (Pisum sativum) shares similarity with metallothionein (MT) genes and related sequences have also been isolated from a number of other higher-plant species. The proteins encoded by these genes have not yet been purified from plants and their functions remain unclear although, by analogy to MT, roles in the metabolism and detoxification of metal ions have been proposed. By contrast, correlation between transcript abundance and Fe availability has led to an alternative proposal that these genes are involved in mechanisms of Fe efficiency. Phenotypic effects of constitutive PsMT A expression were examined in Escherichia coli and Arabidopsis thaliana. Copper accumulation by E. coli cells expressing recombinant PsMTA protein was approximately 8-fold greater than in control cells. No significant effects on the accumulation of Zn or Cd were detected. In segregating A. thaliana progeny, derived from a transgenic F1 parent containing the PsMT A gene under the control of a CaMV 35S promoter, 75% of individuals accumulated more Cu (several-fold in some plants) than untransformed, control plants. These data suggest that PsMTA protein binds Cu in planta and that uncoupled (constitutive) expression of the PsMT A gene causes enhanced Cu accumulation. Roots of P. sativum plants grown under conditions of low Fe availability showed elevated activity of root surface Fe(III) reductase and accumulated more Cu than roots of plants grown in an Fe-supplemented solution. Changes in the expression of MT-like genes, coincident with changes in Fe availability, are consistent with a role in Cu homoeostasis.
    Type of Medium: Electronic Resource
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  • 8
    Publication Date: 2021-04-25
    Description: The first starfish bed to be recognized from the Antilles is a lensoid body in the middle Miocene Grand Bay Formation of Carriacou, The Grenadines (West Indies). This unit was deposited in a turbidite basin in a region of active volcanism fed from one centre and preserves common deep-water taxa more typical of the Palaeozoic, such as crinoids and brachiopods. The starfish bed is a channel-fill deposit laid down in at least 150–200 m water depth, although the specimens may have been derived from shallower water. A goniasterid asteroid and an ophiacanthid ophiuroid have been recognized. The first articulated asteroid from the Antillean fossil record is Paragonaster(?) haldixoni sp. nov. In all skeletal features it appears close to the extant Atlantic species Paragonaster grandis H. L. Clark and P. subtilis (Perrier), but differs in having a single row of rectangular abactinal ossicles extending to the arm tip; these are longer than wide. The brittlestar, Ophiocamax ventosa sp. nov., is described on the basis of a fragmentary disc and arms from this deposit. The closest similarities are with the extant tropical western Atlantic species Ophiocamax hystrix Lyman and O. austera Verrill. However, the new species has thorns covering the entire surface of dorsal arm plates, while arm spines have a multitude of small thorns, loosely arranged in numerous rows and dorsal arm plate shape differs markedly. The occurrence of O. ventosa sp. nov. suggests that Ophiocamax has been a deep-sea taxon at least since the Miocene.
    Keywords: Asteroidea; Goniasteridae; Ophiuroidea; Ophiocanthidae; deep water ; 551
    Language: German
    Type: article , publishedVersion
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