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  • 1
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Journal of the American Chemical Society 92 (1970), S. 208-209 
    ISSN: 1520-5126
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 57 (2002), S. 0 
    ISSN: 1365-2044
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Inorganic chemistry 7 (1968), S. 1208-1214 
    ISSN: 1520-510X
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Journal of the American Chemical Society 90 (1968), S. 2189-2190 
    ISSN: 1520-5126
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    Computers in Human Behavior 6 (1990), S. 69-81 
    ISSN: 0747-5632
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Informatik , Medizin , Psychologie
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Der Radiologe 36 (1996), S. 855-858 
    ISSN: 1432-2102
    Schlagwort(e): Schlüsselwörter CTA ; Basilarisverschluß ; Basilaristhrombose ; Key words Basilar artery ; Occlusion ; Thrombosis ; Diagnosis ; Spiral CT angiography
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Summary Background and purpose: Without recanalisation, acute basilar artery (BA) occlusion has a mortality of 90 %, which is reduced to 50 % if recanalisation is achieved. Fast diagnosis of BA occlusion is necessary in order to start thrombolytic therapy without delay. We wanted to assess the role of CT angiography (CTA) in the diagnostic evaluation of suspected acute BA occlusion. Materials and methods: Ten patients with clinically suspected BA occlusion were examined with conventional CT and spiral CT angiography. Spiral scanning extended from the foramen magnum to the tip of the basilar artery. For CTA, 130 ml of nonionic contrast media were injected into an antecubital vein. In four patients, transfemoral digital subtraction angiography (DSA) was additionally performed. All but one patient had a follow-up CT examination the next day. Results: CTA demonstrated BA occlusion in six patients and a partially thrombosed megadolichobasilar artery in one patient. In four of the six patients with CT angiographically diagnosed BA occlusion, an additional DSA was performed, which confirmed the CTA findings. In three patients the BA showed normal intravasal contrast, and follow-up CT did not show infarctions in the vertebrobasilar territory. Conclusion: Although the number of cases is still small, CTA seems to be a promising method for the rapid diagnosis of BA occlusion. It may become a valuable tool for therapy decisions in acute BA occlusions.
    Notizen: Zusammenfassung Die Letalität nicht rekanalisierter akuter Basilarisverschlüsse liegt bei 90 %. Erfolgt eine Rekanalisation, sinkt die Mortalität auf etwa 50 %. Eine schnelle Diagnostik eines Basilarisverschlusses ist erforderlich, um gegebenenfalls eine thrombolytische Therapie zu beginnen. Wir berichten über erste Erfahrungen mit der CT-Angiographie (CTA) in der Diagnose akuter Basilarisverschlüsse. Bei 10 Patienten mit klinisch begründetem Verdacht auf einen Basilarisverschluß wurde eine CTA des hinteren Hirnkreislaufs durchgeführt, die bei 6 Patienten einen Verschluß der A. basilaris und bei einem Patienten eine teilthrombosierte Megadolicho-Basilaris zeigte. Bei 4 der 6 Patienten mit CT-angiographisch nachgewiesenem Basilarisverschluß wurde eine DSA durchgeführt, die die Diagnose bestätigte. Bei 3 Patienten, bei denen sich die gesamte A. basilaris in der CTA regelrecht kontrastierte, zeigte das Kontroll-CT keine Infarkte. Wenngleich unsere Fallzahlen noch gering sind, scheint die CTA ein vielversprechendes, schnelles Verfahren zur Diagnostik akuter Basilarisverschlüsse zu sein und könnte ein wichtiges Hilfsmittel bei Therapieentscheidungen werden.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
    ISSN: 1432-1920
    Schlagwort(e): Cerebral ischaemia ; Magnetic resonance imaging ; Contrast media ; Superparamagnetic iron oxide ; Stroke model ; Cerebral blood flow
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract An imaging technique capable of detecting ischaemic cerebral injury at an early stage could improve diagnosis in acute or transient cerebral ischaemia. We compared the ability of superparamagnetically contrastenhanced MRI and conventional T2-weighted MRI to detect ischaemic injury early after unilateral occlusion of the middle cerebral artery in 12 male Wistar rats. Permanent vessel occlusion was achieved by a transvascular approach, which has the advantage of not requiring a craniectomy. At 45–60 min after the procedure, the animals had conventional T2-weighted MRI before and after administration of a superparamagnetic contrast agent (iron oxide particles). Unenhanced images were normal in all animals. After administration of iron oxide particles, the presumed ischaemic area was clearly visible, as relatively increased signal, in all animals; this high signal area corresponded to the area of ischaemic brain infarction seen on histological studies. Magnetic susceptibility effects of iron particles cause low signal in normally perfused cerebral tissue, whereas tissue with reduced or absent blood flow continues to give relatively high signal. Our results suggest that superparamagnetic iron particles may significantly reduce the interval between an ischaemic insult and the appearance of parenchymal changes on MRI.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
    ISSN: 1432-1920
    Schlagwort(e): Cerebral ischaemic ; Ischaemic infarcts ; Cranial computed tomography
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract To determine how early and how reliably ischaemic brain infarcts can be detected on CT within 6 h of the onset of cerebral hemisphere strokes, 44 such studies were interpreted by an experienced neuroradiologist blinded to clinical signs, but aware that the cohort was a stroke population. He was asked to detect and localise an area of parenchymal low density and/or focal brain swelling. A follow-up study showing the definite infarct served as a reference in each case. In 38 patients areas of slightly low density were seen, and in 36 follow-up CT confirmed infarcts in the locations indicated. In 2 patients the reading was false positive. In 6 patients no low density focus could be detected. In these 8 patients examined by CT within 180 min of the stroke, no low density could be identified, even in retrospect with the knowledge of the findings on follow-up. Thus, 42 readings (95%) were true positive or true negative; 2 were false positive; and none was a false negative. CT within 6 h of the onset of symptoms has a mean sensitivity of 82% (36/44) for ischaemic cerebral hemisphere infarcts. By contrast, its sensitivity to ischaemic parenchymal low density is low during the initial 2 h. The early development of hemispheric infarcts can be detected reliably if the radiologist is familiar with the signs.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 9
    ISSN: 1432-1920
    Schlagwort(e): Key words Cerebral ischaemic ; Ischaemic infarcts ; Cranial computed tomography
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract To determine how early and how reliably ischaemic brain infarcts can be detected on CT within 6 h of the onset of cerebral hemisphere strokes, 44 such studies were interpreted by an experienced neuroradiologist blinded to clinical signs, but aware that the cohort was a stroke population. He was asked to detect and localise an area of parenchymal low density and/or focal brain swelling. A follow-up study showing the definite infarct served as a reference in each case. In 38 patients areas of slightly low density were seen, and in 36 follow-up CT confirmed infarcts in the locations indicated. In 2 patients the reading was false positive. In 6 patients no low density focus could be detected. In these 8 patients examined by CT within 180 min of the stroke, no low density could be identified, even in retrospect with the knowledge of the findings on follow-up. Thus, 42 readings (95 %) were true positive or true negative; 2 were false positive; and none was a false negative. CT within 6 h of the onset of symptoms has a mean sensitivity of 82 % (36/44) for ischaemic cerebral hemisphere infarcts. By contrast, its sensitivity to ischaemic parenchymal low density is low during the initial 2 h. The early development of hemispheric infarcts can be detected reliably if the radiologist is familiar with the signs.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 10
    ISSN: 1432-1920
    Schlagwort(e): Key words Fistula ; arteriovenous ; Embolisation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We report our experience in using Guglielmi electrolytically detachable coils (GDC) alone or in combination with other materials in the treatment of intracranial or cervical high-flow fistulae. We treated 14 patients with arteriovenous fistulae on brain-supplying vessels – three involving the external carotid or the vertebral artery, five the cavernous sinus and six the dural sinuses – by endovascular occlusion using electrolytically detachable platinum coils. The fistula was caused by trauma in six cases. In one case Ehlers-Danlos syndrome was the underlying disease, and in the remaining seven cases no aetiology could be found. Fistulae of the external carotid and vertebral arteries and caroticocavernous fistulae were reached via the transarterial route, while in all dural fistulae a combined transarterial-transvenous approach was chosen. All fistulae were treated using electrolytically detachable coils. While small fistulae could be occluded with electrolytically detachable coils alone, large fistulae were treated by using coils to build a stable basket for other types of coil or balloons. In 11 of the 14 patients, endovascular treatment resulted in complete occlusion of the fistula; in the remaining three occlusion was subtotal. Symptoms and signs were completely abolished by this treatment in 12 patients and reduced in 2. On clinical and neuroradiological follow-up (mean 16 months) no reappearance of symptoms was recorded.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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