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  • 1
    Book
    Book
    The geology of North America; Vol. I-1: Geology of the continental margin of eastern Canada / Geological Survey of Canada. Ed. by M. J. Keen ..., [Kt.] (1990)
    Boulder, Colo. : Geological Society of America
    Associated volumes
    Details Availability
    Keywords: Karte
    In: Vol. I-1, [Kt.]
    Type of Medium: Book
    Pages: 17 Kt.
    ISBN: 0660131307
    Series Statement: Geology of Canada 2
    Language: English
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  • 2
    Book
    Book
    The geology of North America; Vol. I-1: Geology of the continental margin of eastern Canada / Geological Survey of Canada. Ed. by M. J. Keen ..., [Hauptbd.] (1990)
    Boulder, Colo. : Geological Society of America
    Associated volumes
    Details Availability
    In: Vol. I-1, [Hauptbd.]
    Type of Medium: Book
    Pages: V, 855 S. , graph. Darst., Kt.
    ISBN: 0660131307
    Series Statement: Geology of Canada 2
    Language: English
    Note: Literaturangaben
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  • 3
    Online Resource
    Online Resource
    An Introduction to Marine Geology. (1968)
    Amsterdam :Elsevier Science & Technology,
    Details
    Keywords: Submarine geology. ; Submarine topography. ; Electronic books.
    Description / Table of Contents: An account of some aspects of marine geology and marine geophysics, comprehensible to those at an early stage in their study of geology and to scientists who are not specialists in these fields. There are many biologists, chemists, mathematicians or physicists who work in the laboratory or on board ship with geologists and geophysicists and this book will help them to understand the aims of their colleages' experiments. Wherever possible, without a loss of necessary precision, terminology is deliberately simplified.
    Type of Medium: Online Resource
    Pages: 1 online resource (231 pages)
    Edition: 1st ed.
    ISBN: 9781483293493
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=1838278
    DDC: 551.4608
    Language: English
    Note: Front Cover -- An Introduction to Marine Geology -- Copyright Page -- Table of Contents -- Preface -- Acknowledgements -- CHAPTER 1. Introduction -- THE GROSS STRUCTURE OF THE EARTH -- THE ROCKS WHICH FORM THE OUTER PART OF THE EARTH -- ROCK-FORMING MINERALS -- IGNEOUS ROCKS -- A CLASSIFICATION OF IGNEOUS ROCKS -- CHAPTER 2. Geophysical Techniques for Exploration of the Sea Floor -- INTRODUCTION -- EXPLOSION SEISMOLOGY -- REFLECTIONS: ECHO-SOUNDING AND SEISMIC-PROFILING -- SEISMOLOGICAL INVESTIGATIONS: EARTHQUAKES -- GRAVITY AT SEA -- THE TOTAL INTENSITY OF THE MAGNETIC FIELDOF THE EARTH -- MEASUREMENT OF HEAT-FLOW -- OTHER METHODS AND DEVELOPMENTS -- CHAPTER 3. The Topography of the Ocean Floor -- THE CONTINENTAL MARGIN -- THE OCEAN BASIN FLOOR -- MID-OCEAN RIDGE SYSTEM -- THE SIGNIFICANCE OF TOPOGRAPHY -- CHAPTER 4. Pelagic Sediments -- INTRODUCTION AND DEFINITIONS -- FAUNA AND FLORA -- DETERMINATION OF THE ABSOLUTE AGE -- MAGNETIZATION OF SEDIMENTS: MAGNETIC STRATIGRAPHY -- MINERALOGY AND GEOCHEMISTRY OF PELAGIC SEDIMENTS -- APPLICATIONS OF STUDIES OF PELAGIC SEDIMENTS -- CHAPTER 5. Abyssal Plain Sediments -- INTRODUCTION -- THE SEDIMENTS OF THE IBERIA ABYSSAL PLAIN -- THE JUNCTION OF THE BISCAY AND IBERIA PLAINS -- TURBIDITES OF FORMER TIMES -- CHAPTER 6. Movements of the Sea Floor -- THE INTEREST -- CORAL REEFS AND GUYOTS -- SUBSIDENCE AND ELEVATION -- LATERAL DISPLACEMENTS: MAGNETIC ANOMALIES IN THE EASTERN PART OF THE PACIFIC OCEAN -- CHAPTER 7. Igneous Rochof the Ocean Basins -- BASIC AND ULTRABASIC IGNEOUS ROCKS -- IGNEOUS ROCKS OF THE OCEAN BASINS -- OCEANIC ISLANDS -- IGNEOUS ROCKS FROM THE MID-OCEAN RIDGES -- BASALTS FROM THE IBERIA ABYSSAL PLAIN -- MANGANESE IN THE OCEAN BASINS -- INHOMOGENEITIES WITHIN THE UPPER MANTLE -- SUMMARY -- CHAPTER 8. The Structure of the Ocean Basins -- THE MID-OCEAN RIDGE SYSTEM -- THE CONTINENTAL MARGINS. , CHAPTER 9. Polar Wandering and Continental Drift -- CONTINENTAL DRIFT: OCEAN-FLOOR SPREADING -- APPENDIX 1: Geological Society ofLondon PhanerozoicTime-scale 1964 -- APPENDIX 2: Rock-forming Silicates -- References -- Index.
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  • 4
    Electronic Resource
    Electronic Resource
    Magnetic Anomalies over the Mid-Atlantic Ridge (1963)
    [s.l.] : Nature Publishing Group
    Nature 197 (1963), S. 888-890 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. Tracks of the flights. The heavy broken line is the approximate position of the crest of the Mid-Atlantic Ridge (see text). The circles correspond to the points on the centre line of Fig. 2 Ewing, Heezen and Hirshman1 have pointed out that work at sea has shown that the crest of the Ridge ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/197888a0
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  • 5
    Electronic Resource
    Electronic Resource
    Size Analyses of Turbidity Current Sediment (1963)
    [s.l.] : Nature Publishing Group
    Nature 197 (1963), S. 372-373 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Size analyses were made on two of the beds of sediment which had been deposited by turbidity currents to see how the grain size of the sediment varies with the depth in the bed. Such an investigation is necessary if quantitative studies are to be made on the settling of sediment from a turbidity ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/197372a0
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  • 6
    Electronic Resource
    Electronic Resource
    Magnetization of Sediment Cores from the Eastern Atlantic Ocean (1960)
    [s.l.] : Nature Publishing Group
    Nature 187 (1960), S. 220-222 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE remanent magnetization of sediments from the continents has been studied extensively ; but only a few studies have been made on sediments from the oceans1,2. This article describes the results of experiments which have been made on two of a number of cores from the eastern Atlantic Ocean. The ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/187220a0
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  • 7
    Electronic Resource
    Electronic Resource
    Possible Edge Effect to explain Magnetic Anomalies off the Eastern Seaboard of the US (1969)
    [s.l.] : Nature Publishing Group
    Nature 222 (1969), S. 72-74 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Smoothed field Fig. 1. Smoothed magnetic anomaly field. 100 gamma contour interval. Ordinates, latitude X and longitude W, degrees. Limit of smoothed data to the east shown by jagged line. Dashed line on right, 4,000 m depth contour. Line of squares on left, 2,000 m depth contour. Inset, area of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/222072a0
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  • 8
    Electronic Resource
    Electronic Resource
    Ocean-ridge basalt compositions correlated with palaeobathymetry (1990)
    [s.l.] : Nature Publishing Group
    Nature 345 (1990), S. 423-426 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The Ocean Drilling Program's Hole 647A in the extinct mid-ocean ridge of the Labrador Sea illustrates our approach (Figs 1 and 2). Basalts were encountered at 4,561 m below sea level, beneath 699 m of sediment3'4. They are typical mid-ocean-ridge basalts (MORB), 56 Myr old, but still fresh5. Values ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/345423a0
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  • 9
    Electronic Resource
    Electronic Resource
    Adaptation of cholesterol-requiring NS0 mouse myeloma cells to high density growth in a fully defined protein-free and cholesterol-free culture medium (1995)
    Springer
    Cytotechnology 17 (1995), S. 203-211 
    Details
    ISSN: 1573-0778
    Keywords: NS0 ; mouse myeloma ; cholesterol-free ; cholesterol auxotroph ; protein-free
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract NS0 has been used as a fusion partner for the production of hybridomas and has more recently been engineered to produce recombinant protein. A protein-free culture medium, designated W38 medium, has previously been developed which supported high density growth of rat myeloma and hybridoma cell lines. NS0 cells failed to grow in W38 medium and in a number of protein-free culture media which support the growth of other myeloma cell lines. NS0 cells are derived from the NS-1 cell line, which is known to require exogencus cholesterol. It was found that NS0 cells grew in W38 medium supplemented with phosphatidylcholine, cholesterol, and albumin and that NS0 were auxotrophic for cholesterol. Protein-free growth of NS0 cells was achieved by using β-cyclodextrin to replace albumin as a lipid carrier. The maximal cell density reached in this protein-free medium was in excess of 1.5×106 cell ml−1. The lipid supplements in the medium precipitated after a few days storage at +4°C. In order to overcome this problem a protocol was developed which allowed NS0 cells to be adapted to cholesterol-independent growth in W38 medium. NS0.CF (cholesterol-independent NS0 cells) were cultured continuously in W38 medium for several months. In shake flask culture a cell density of 2.4×106 cells ml−1 was achieved in W38 medium compared with 1.41×106 cells ml−1 in RPMI 1640 medium containing 10% foetal bovine serum. NS0.CF cells readily grew in a 1 litre stirred bioreactor using W38 medium supplemented with Pluronic F68 reaching a density of 3.24×106 cells ml−1. NS0.CF were cloned protein-free by limiting dilution in W38 medium, giving colonies in wells that were seeded at an average density of 0.32 cells per 200 μl. This study has demonstrated for the first time the growth of a cholesterol-requiring mouse myeloma cell line in a completely defined protein-free medium and its subsequent adaptation to cholesterol-independence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00749658
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  • 10
    Electronic Resource
    Electronic Resource
    The use of serum-free medium for the production of functionally active humanised monoclonal antibody from NS0 mouse myeloma cells engineered using glutamine synthetase as a selectable marker (1995)
    Springer
    Cytotechnology 18 (1995), S. 207-217 
    Details
    ISSN: 1573-0778
    Keywords: serum-free ; mouse myeloma ; NS0 cells ; humanised monoclonal antibody ; glutamine synthetase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A protein-free growth medium (W38 medium) had previously been developed for the NS0 mouse myeloma cell line which is cholesterol-auxotrophic. This paper describes the development of a protein-free growth medium for NS0 cells expressing humanised monoclonal antibody using GS (glutamine synthetase) as a selectable marker. Several GS-engineered NS0 cell lines expressing humanised monoclonal antibody grew in a modification of W38 medium which maintained GS-selection, supplemented with cholesterol, phosphatidylcholine and β-cyclodextrin. Further studies showed that additional glutamic acid, asparagine, ribonucleosides and choline chloride improved cell growth. Amino acid analysis identified a number of amino acids that were being depleted from the culture medium. NS0 cell lines 9D4 and 2H5 expressing CAMPATH-1H* were adapted to enable them to grow serum-free in the absence of cholesterol and β-cyclodextrin. Cholesterol-independent 9D4 (9D4.CF) cells grown in shake flask culture using an enriched protein-free medium (WNSD medium), supplemented with human recombinant insulin (Nucellin), reached a maximum cell density to 1.86×106 cells ml−1 producing 76.6 mg l−1 of antibody. CAMPATH-1H antibody produced using serum-free medium was found to be functionally activein vitro in the Antibody Dependant Cellular Cytotoxicity (ADCC) assay.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00767768
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