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  • 1
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    Finite frequency effects on apparent S-wave splitting in the D'' layer: comparison between ray theory and full-wave synthetics (2016)
    Oxford University Press
    Details
    Publication Date: 2016-08-05
    Description: We conduct a numerical experiment to investigate potential bias in measurements of S -wave splitting (apparent differences between the arrival times of SH and SV phases) for waves propagating close to the core–mantle boundary (CMB) in the D'' layer. The bias is defined as the discrepancy between shear wave splitting measured from finite frequency synthetic seismograms (‘apparent splitting’) and the splitting predicted by ray theory, which is a high-frequency approximation. For simple isotropic models, we find biases which are typically between 0.5 and 4 s, depending on the model, the Q structure and the dominant period of the synthetics. The bias increases for lower frequencies or lower Q values. The epicentral distance at which the bias starts depends on the frequency and the Q structure. We also compute synthetics for models based on mineral physics (using the elastic constants under lower-mantle pressure and temperature conditions, taking into account the phase transition from Mg-perovskite to Mg-post-perovskite) and geodynamics (the thermal boundary layer) and find that the depth of the positive velocity jump associated with the phase transition and the depth range over which the velocity decreases (due to temperature increases) in the thermal boundary layer significantly influence the wavefield in the lowermost mantle. For example, in cold regions beneath subduction zones, wavefields for SH and SV differ greatly due to the steep velocity decrease close to the CMB. For complex models, apparent splitting can also arise from the possibility that low amplitude direct phases might be overlooked, and larger amplitude later phases might instead incorrectly be picked as the direct arrival. Biases of the type investigated in this study combine with other sources of uncertainty for splitting in D'' (e.g. the correction for upper-mantle anisotropy and the difference between SH and SV ray paths) to make a precise evaluation of the anisotropy in D'' difficult.
    Keywords: Seismology
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 2
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    Waveform inversion for localized three-dimensional seismic velocity structure in the lowermost mantle beneath the Western Pacific (2014)
    Oxford University Press
    Details
    Publication Date: 2014-09-30
    Description: We infer 3-D localized shear velocity structure in the lowermost 400 km of the mantle at the western edge of the Pacific large low shear velocity province (LLSVP) by applying waveform inversion to transverse component body-wave waveforms from the F-net seismic array in Japan. Our data set consists of relatively long period (12.5–200 s) broad-band seismic waveforms of Tonga-Fiji deep focus and intermediate deep earthquakes. We conduct several tests to confirm the robustness of the inversion results. We find two low-velocity zones at the bottom of the target region, with a high-velocity zone in the middle, and a low-velocity zone above the high-velocity zone and contiguous with the two deeper low-velocity zones at a depth of 200–300 km above the core-mantle boundary (CMB). This supports the idea that the Pacific LLSVP may be an aggregation of small upwelling plumes rather than a single large thermochemical pile.
    Keywords: Seismology
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 3
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    Prognostic index for chronic- and smoldering-type adult T-cell leukemia-lymphoma (2017)
    American Society of Hematology (ASH)
    In: Blood
    Details
    Publication Date: 2017-07-07
    Description: Adult T-cell leukemia-lymphoma (ATL) has been divided into 4 clinical subtypes: acute, lymphoma, chronic, and smoldering. The aim of this study is to develop a novel prognostic index (PI) for chronic and smoldering ATL. We conducted a nationwide retrospective survey on ATL patients, and 248 fully eligible individuals were used in this analysis. In the univariate analysis, sex, performance status, log 10 (soluble interleukin-2 receptor [sIL-2R]), neutrophils count, and lymphadenopathy showed values of P 〈 .05 in training samples. A multivariate analysis was performed on these factors, and only log 10 (sIL-2R) was identified as an independent prognostic factor in training samples. Using a regression coefficient of this variable, a prognostic model was formulated to identify different levels of risk: indolent ATL-PI (iATL-PI) = 1.51 x log 10 (sIL-2R [U/mL]). The values calculated by iATL-PI were divided into 3 groups using a quartile point. In the validation sample, median survival times (MSTs) were 1.6 years, 5.5 years, and not reached for patients in the high-, intermediate-, and low-risk groups, respectively ( P 〈 .0001). To make the scoring system clinically practicable, we simplified iATL-PI according to trichotomizing sIL-2R at 1000 and 6000 U/mL, using a quartile point. Patients with more than 6000 U/mL sIL-2R were categorized into the high-risk group, less than and equal to 1000 U/mL into the low-risk group, and the others into the intermediate-risk group, and MSTs were 1.6 years, not reached, and 5.5 years, respectively ( P 〈 .0001). iATL-PI has potential as a novel tool for a risk-adapted therapeutic approach.
    Keywords: Free Research Articles, Lymphoid Neoplasia, Clinical Trials and Observations
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
    Published by American Society of Hematology (ASH)
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  • 4
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    Proline dehydrogenase promotes senescence through the generation of reactive oxygen species [Articles of interest in other COB journals] (2017)
    The Company of Biologists
    Details
    Publication Date: 2017-05-03
    Description: Taiki Nagano, Akio Nakashima, Kengo Onishi, Kosuke Kawai, Yuto Awai, Mizuki Kinugasa, Tetsushi Iwasaki, Ushio Kikkawa, and Shinji Kamada
    Print ISSN: 0950-1991
    Electronic ISSN: 1477-9129
    Topics: Biology
    Published by The Company of Biologists
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  • 5
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    Temperature effects on pathogenicity of selected Edwardsiella tarda strain to Japanese eel, Anguilla japonica (2021)
    In:  http://aquaticcommons.org/id/eprint/18985 | 12051 | 2015-12-01 21:12:26 | 18985 | Bangladesh Fisheries Research Institute
    Details
    Publication Date: 2021-07-12
    Description: Temperature effect on the pathogenicity of selected Edwardsiella tarda V-1 strain to Japanese eel, Anguilla japonica was investigated. To evaluate the effects of both pathogen incubation temperature and fish cultivation temperature on pathogen pathogenicity a two-factor design was conducted. E. tarda was incubated at 15, 20, 25, 30 and 37±1°C, and the fish (mean weight: 100g) were reared at 15, 20, 25 and 28±1°C respectively. The fish reared at different temperatures were infected with the E. tarda incubated at different temperatures. The results of a 4-day LD50 test showed that temperature significantly affected the pathogenicity of E. tarda (p〈0.01) and the interaction between the two factors was also significant (p〈0.01). For fish reared at 20°C the pathogenicity of E. tarda was the highest at 30°C of pathogen incubation. When the fish rearing temperature was raised to 25 and 28°C, the pathogenicity of E. tarda incubated at all temperatures increased. Isolation testing demonstrated results similar to those of LD50. The selected isolate was virulent to eel, but pathogenicity varied with temperature.
    Keywords: Aquaculture ; Fisheries ; Health ; Edwardsiella tarda ; pathogenicity ; Japanese eel ; Anguilla japonica
    Repository Name: AquaDocs
    Type: article
    Format: application/pdf
    Format: application/pdf
    Format: 65-73
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  • 6
    Electronic Resource
    Electronic Resource
    Electronic structure of some I–III–VI2 chalcopyrite semiconductors studied by synchrotron radiation (1992)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 71 (1992), S. 441-447 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Photoemission spectra were measured for the I–III–IV2 chalcopyrite semiconductors CuInSe2, CuInS2, CuInTe2, and CuGaS2 with various photon energies (32 to 140, and 1253 eV). The partial density-of-states (DOS) of Cu 3d orbital is selectively observed at the photon energies beyond 100 eV. The DOS of Cu 3d spreads from the top of valence band (VB) to 5 or 6 eV below. Three dominant peaks are labeled as A, B, and C, the structures of which are interpreted as antibonding, nonbonding, and bonding states. Reflection spectra were also measured for CuInSe2 from 2 to 100 eV at room temperature and 98.5 K. The In 4d core reflection is observed at 17.5, 18.9, 19.8, and 21.2 eV at 98.5 K; very similar characteristics are also observed at 5.28, 6.21, 7.35, and 8.67 eV. These contributions are due to the Cu 3d nonbonding electrons. Photoemission and reflection experiments thus confirm conclusively the existence of nonbonding Cu 3d states in I–III–VI2 chalcopyrites. This result proves the theoretical model that attributes the upper VB to the antibonding state, in contrast with the bonding state of sp3-hybridized semiconductors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.350675
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  • 7
    Electronic Resource
    Electronic Resource
    Generation of poloidally rotating spheromaks by the conical theta pinch (1987)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 30 (1987), S. 2561-2568 
    Details
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Spatially resolved spectroscopic measurements revealed the existence of poloidal vortex motion in spheromaks produced in a conical theta pinch. The poloidal velocity on the axis was estimated to be 5 cm/μsec. Large Doppler broadening, which previously was inferred as high ion temperature, is attributed to large internal fluid velocity. A possible effect of the vortex motion in a spheromak merging experiment is studied and found to enhance the fusion reaction rate as a finite temperature beam collider.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.866094
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  • 8
    Electronic Resource
    Electronic Resource
    Raman spectral study on the solution structure of the chromium(III)-EDTA complex (1986)
    s.l. : American Chemical Society
    Inorganic chemistry 25 (1986), S. 3711-3713 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic00240a041
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  • 9
    Electronic Resource
    Electronic Resource
    Effect of different proton pump inhibitors, differences in CYP2C19 genotype and antibiotic resistance on the eradication rate of Helicobacter pylori infection by a 1-week regimen of proton pump inhibitor, amoxicillin and clarithromycin (2003)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 17 (2003), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aim : To investigate the effect of different proton pump inhibitors, S-mephenytoin 4′-hydroxylase (CYP2C19) genotype and antibiotic susceptibility on the eradication rate of Helicobacter pylori.Methods : One hundred and eighty-seven H. pylori-infected peptic ulcer patients were randomly treated with either rabeprazole (10 mg b.d.) or lansoprazole (30 mg b.d.) plus amoxicillin (750 mg b.d.) and clarithromycin (400 mg b.d.) for 1 week. The antibiotic susceptibility and CYP2C19 genotype (extensive or poor metabolizer) were investigated.Results : The eradication rates in the rabeprazole–amoxicillin–clarithromycin (RAC) and lansoprazole–amoxicillin–clarithromycin (LAC) groups were 75% and 69%, respectively, on an intention-to-treat basis, and 80% and 75%, respectively, on a per protocol basis. The eradication rate for clarithromycin-resistant strains was significantly lower than that for clarithromycin-sensitive strains (24% vs. 86%, P 〈 0.05). For clarithromycin-sensitive strains in the LAC group, there was a tendency for a lower eradication rate in extensive than poor metabolizers. The eradication rate in extensive metabolizers in the RAC group tended to be higher than that in extensive metabolizers in the LAC group (89% vs. 78%, P = 0.079726).Conclusions : The success of the 1-week proton pump inhibitor–amoxicillin–clarithromycin regimen depends on the susceptibility of H. pylori to clarithromycin. Moreover, differences in CYP2C19 genotype influence the eradication rates of lansoprazole-based therapy, and the rabeprazole-based regimen has an advantage especially in extensive metabolizers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2003.01406.x
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  • 10
    Electronic Resource
    Electronic Resource
    CD56-negative blastic natural killer-cell lymphoma (agranular CD4+/CD56+ haematodermic neoplasm)? (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 152 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.06296.x
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