In:
European Journal of Organic Chemistry, Wiley, Vol. 2010, No. 28 ( 2010-10), p. 5489-5497
Kurzfassung:
An effective protocol has been developed for the construction of 3,3‐disubstituted indol‐2‐ones from isatylidenes by utilizing amphiphilic bis‐π‐allylpalladium and related intermediates. The developed strategy is a new method for the quaternization of position 3 of the indol‐2‐one towards disubstituted functionalized indol‐2‐ones. These products were subjected to ring‐closing metathesis towards the synthesis of spiro[cyclohexene‐1,3′‐indol]‐2′‐ones and spiro[oxep‐5‐ene‐2,3′‐indol] ‐2′‐ones, which are of biological interest.
Materialart:
Online-Ressource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2010:28
DOI:
10.1002/ejoc.201000604
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2010
ZDB Id:
1475010-7
Permalink